Abstract:
:A dental appointment commonly prompts fear of a painful experience, yet we have never fully understood how our brains react to the expectation of imminent tooth pain once in a dental chair. In our study, 21 patients with hypersensitive teeth were tested using nonpainful and painful stimuli in a clinical setting. Subjects were tested in a dental chair using functional near-infrared spectroscopy to measure cortical activity during a stepwise cold stimulation of a hypersensitive tooth, as well as nonpainful control stimulation on the same tooth. Patients' sensory-discriminative and emotional-cognitive cortical regions were studied through the transition of a neutral to a painful stimulation. In the putative somatosensory cortex contralateral to the stimulus, 2 well-defined hemodynamic peaks were detected in the homuncular orofacial region: the first peak during the nonpainful phase and a second peak after the pain threshold was reached. Moreover, in the upper-left and lower-right prefrontal cortices, there was a significant active hemodynamic response in only the first phase, before the pain. Subsequently, the same prefrontal cortical areas deactivated after a painful experience had been reached. Our study indicates for the first time that pain perception and expectation elicit different hemodynamic cortical responses in a dental clinical setting.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Racek AJ,Hu X,Nascimento TD,Bender MC,Khatib L,Chiego D Jr,Holland GR,Bauer P,McDonald N,Ellwood RP,DaSilva AFdoi
10.1177/0022034515581642subject
Has Abstractpub_date
2015-07-01 00:00:00pages
998-1003issue
7eissn
0022-0345issn
1544-0591pii
0022034515581642journal_volume
94pub_type
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