Fluoride inhibition of polymorphonuclear leukocytes.

Abstract:

:Significant inhibition of PMN metabolic activity by F- occurred at 0.1, 0.5 and 0.0 mM F- for O2- generation, 1-C14 CO2 release labeled glucose and NBT-reduction respectively. This inhibition resulted primarily from F- suppression of nonoxidative glucose metabolism. As the concentration of F- in the O2- generating system increased beyond 10 mM, a rise in production of O2- anion occurred, peaking at 20 mM F-, followed by a rapid decline.

journal_name

J Dent Res

authors

Gabler WL,Leong PA

doi

10.1177/00220345790580092101

subject

Has Abstract

pub_date

1979-09-01 00:00:00

pages

1933-9

issue

9

eissn

0022-0345

issn

1544-0591

journal_volume

58

pub_type

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