Abstract：
:The aims of this work were (a) to assess the oral bioavailability of fluoride delivered from dentifrices and (b) to test for a possible link between the results and clinical data obtained with the same dentifrices. Oral fluoride concentrations were measured in samples of saliva and plaque taken from seven subjects, after use of dentifrices which contained 0, 1000, 1500, and 2500 micrograms F/g as sodium monofluorophosphate. Salivary fluoride in samples obtained within the first few hours after a single dentifrice application, or up to 20 h after four weeks' daily use, increased with increasing F content of the dentifrice. For example, the mean zero-time intercepts of the second phase of salivary fluoride clearance curves for the above dentifrices were 0.46, 1.48, 1.88, and 3.03 mumol F/L, respectively. Plaque fluoride measured after four weeks' daily use of the dentifrices exhibited similar dose-response behavior. Linear regression analysis showed these trends to be statistically significant for both saliva (p less than 0.001) and plaque (p less than 0.025). Mean saliva and plaque fluoride concentrations were inversely associated with mean three-year caries increments for the three fluoride-containing dentifrices obtained in a recent clinical trial: DMFS scores 6.80, 6.33, and 5.71, respectively (Stephen et al., 1988). This suggests that oral fluoride measurements are a valuable in vivo method for the evaluation of the potential anti-caries efficacy of fluoride-containing dental products.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Duckworth RM,Morgan SN,Gilbert RJdoi
10.1177/002203459207100S09keywords:
subject
Has Abstractpub_date
1992-04-01 00:00:00pages
836-40eissn
0022-0345issn
1544-0591journal_volume
71 Spec Nopub_type
临床试验,杂志文章,评审abstract：:The effect of pH on the growth and proteolytic activity of the type strain and fresh isolates of Porphyromonas gingivalis and Bacteroides intermedius was investigated. B. intermedius strains grew with and without glucose at a pH as low as 5.0. These bacteria grew almost as well as Streptococcus mutans at pH 5.0 and be...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345900690060801
更新日期：1990-06-01 00:00:00
abstract：:Teeth to be extracted for orthodontic reasons were filled in vivo with regular and fine-cut silver amalgams containing 1% and 5% SnF2. The teeth were extracted after 15 or 30 d, and the in vivo fluoride release and uptake by the dental tissues were studied using an electron microprobe analysis technique. The obtained ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345810600020101
更新日期：1981-02-01 00:00:00
abstract：:Autosomal dominant mutations in PTH1R segregate with primary failure of eruption (PFE), marked by clinical eruption failure of adult teeth without mechanical obstruction. While the diagnosis of PFE conveys a poor dental prognosis, there are no reports of PFE patients who carry PTH1R mutations and exhibit any other ske...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513513588
更新日期：2014-02-01 00:00:00
abstract：:Heterozygous mutations in the RUNX2 (CBFA1) gene cause cleidocranial dysplasia, characterized by multiple supernumerary teeth. This suggests that Runx2 inhibits successional tooth formation. However, in Runx2 knockout mice, molar development arrests at the late bud stage, and lower molars are more severely affected th...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910508400206
更新日期：2005-02-01 00:00:00
abstract：:The aim of this meta-analysis was to examine the clinical effectiveness of miniscrew implants (MI) used for anchorage reinforcement compared with that of conventional orthodontic means, as well as to assess the success rates of MIs and the possible risk factors affecting their clinical effectiveness. Literature search...
journal_title：Journal of dental research
pub_type： 杂志文章,meta分析,评审
doi：10.1177/0022034511409236
更新日期：2011-08-01 00:00:00
abstract：:Intra-oral wounds, like wounds in children, demonstrate privileged healing when compared with adult wounds at extra-oral sites. This study investigated whether this preferential healing is related to an increased ability of oral mucosal fibroblasts to reorganize extracellular matrix (ECM) when compared with their derm...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345960750060601
更新日期：1996-06-01 00:00:00
abstract：:Caregivers' health literacy has emerged as an important determinant of young children's health care and outcomes. We examined the hypothesis that caregivers' health literacy influences children's oral-health-care-related expenditures. This was a prospective cohort study of 1,132 child/caregiver dyads (children's mean ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513484335
更新日期：2013-07-01 00:00:00
abstract：:An adhesive opaque resin for veneering on cast metal was developed with 4-methacryloxyethyl trimellitate anhydride and poly (methyl methacrylate)-coated titanium dioxide prepared by aqueous phase polymerization. The opaque resin was a modified 4-META/MMA-TBB resin. The powder consisted of 20% of the encapsulated mater...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670010501
更新日期：1988-01-01 00:00:00
abstract：:The frequency and impact of temporomandibular joint (TMJ) disorders necessitate research in characterizing the joint's function. The 6 discal attachments have not yet been systematically characterized under tension. Understanding their role in joint function may guide our study of TMJ pathologies, including disc displ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513494817
更新日期：2013-08-01 00:00:00
abstract：:Enamel abraders used in two-body wear tests suffer the disadvantage that standardization is difficult or impossible to obtain. The aim of this study was to test whether steatite (a ceramic material with a Vickers Hardness similar to that of enamel) could be used as a satisfactory human enamel analogue. The friction an...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345940730091001
更新日期：1994-09-01 00:00:00
abstract：:Temperature elevations were measured in the pulp chamber of full cast crown preparations during impression taking with modelling compound in copper bands. Uncontrolled flaming, controlled flaming, and water heating of the bands produced temperatures of 53, 44, and 41.5 C, respectively. The time involved in restoring t...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：:The effect of toothbrushes on soft tissue abrasion was measured using hamster cheek pouch tissue brushed mechanically for various intervals. The detection of protein removed during brushing was used as an index of tissue abrasion. The method was found to be sensitive in detecting the effects of brush load, number of s...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560070301
更新日期：1977-07-01 00:00:00
abstract：:Fungal infections in the oral cavity are mainly caused by C. albicans, but other Candida species are also frequently identified. They are increasing in prevalence, especially in denture-wearers and aging people, and may lead to invasive infections, which have a high mortality rate. Attachment to mucosal tissues and to...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034508329273
更新日期：2009-02-01 00:00:00
abstract：:Cultures of Streptococcus mutans MFe28 (serotype h) were grown with differing extracellular polysaccharide (EPS) content. Biochemical and physicochemical characteristics considered relevant to caries were measured. Acid production parameters measured in a pH-stat were: Vm = 0.76 +/- 0.14 mumol/g/sec (wet weight); appa...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670060101
更新日期：1988-06-01 00:00:00
abstract：:We conducted a school-based parallel cluster randomized controlled trial with 36-month follow-up of children aged 7 to 8 years. Primary schools were randomly assigned to 2 groups: 3 applications of fluoride varnish (22,600 ppm) each year or no intervention. The primary outcome was DFS increment in the first permanent ...
journal_title：Journal of dental research
pub_type： 杂志文章,随机对照试验
doi：10.1177/0022034511422063
更新日期：2011-11-01 00:00:00
abstract：:A model system consisting of vacuum-deposited aluminum on glass was developed to demonstrate the effectiveness of cavitational activity (occurring within the cooling water supply of a dental ultrasonic scaler) in the removal of particulate material from solid surfaces. The amount of solid material removed from the mod...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630091401
更新日期：1984-09-01 00:00:00
abstract：:Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these enzymes regulate the tiss...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034508330861
更新日期：2009-03-01 00:00:00
abstract：:The aim of the present study was to describe the patterns of dental fluorosis in the primary and the permanent dentition of children born and reared in two different fluoridated areas, one in which powdered milk suspended in tap water was commonly used (Narssaq, Greenland: 1.1 ppm fluoride in the water) and one in whi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670050501
更新日期：1988-05-01 00:00:00
abstract：:Candida colonization of the oral cavity increases in the elderly. A major predisposing condition is denture use, which also increases in the elderly. To test whether the increase in colonization is age-related in a fashion independent of denture use, we analyzed the frequency (incidence) of carriage, the intensity of ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345990780040601
更新日期：1999-04-01 00:00:00
abstract：:Ten dental casting alloys were tested for alloy-element release into cell-culture medium, and this release was related to alloy composition, alloy microstructure, and alloy cytotoxicity (previously determined). Cell-culture medium was analyzed for alloy elements by flame atomic absorption. Concentrations of elements i...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345910700060301
更新日期：1991-06-01 00:00:00
abstract：:The effect of a topical fluoride regimen consisting of a four-minute pre-treatment with a saturated dicalcium phosphate dihydrate (DCPD) solution followed by a four-minute application of APF was compared with that of a four-minute application of APF alone with respect to the deposition of fluoride in enamel in an apat...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650030201
更新日期：1986-03-01 00:00:00
abstract：:Dental caries is a microbially mediated disease that can result in significant tooth structure degradation. Although the preponderance of lesions is treated by surgical intervention, various strategies have been developed for its noninvasive management. Here, we use a novel approach for noninvasive treatment based on ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515619370
更新日期：2016-03-01 00:00:00
abstract：:The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts and cementoblasts. We hypothesized that stem cells may be present in the DF and be capable of differentiating into cells of the periodontium. Stem cells ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910808700801
更新日期：2008-08-01 00:00:00
abstract：:The effects of substituting gluconate for extracellular Cl, and of treatment with various ion transport blockers, on cytosol pH (pHi) and secretion by the acetylcholine stimulated rat mandibular gland were studied in vitro. Gluconate replacement increased pHi from 7.12 +/- 0.02 to 7.27 +/- 0.04, caused secretory rate ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345870660022401
更新日期：1987-02-01 00:00:00
abstract：:The human temporalis and masseter muscles are not activated homogeneously during static bite force tasks. In this study, we studied the possible existence of regional differences in these muscles under dynamic conditions. Electromyographic (EMG) activity was recorded by means of bipolar fine-wire electrodes. Six elect...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345950740061201
更新日期：1995-06-01 00:00:00
abstract：:The balance between bone resorption and bone formation is vital for maintenance and regeneration of alveolar bone and supporting structures around teeth and dental implants. Tissue regeneration in the oral cavity is regulated by multiple cell types, signaling mechanisms, and matrix interactions. A goal for periodontal...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034515618887
更新日期：2016-03-01 00:00:00
abstract：:The inhibitory activity of 2-phosphono-butane 1,2,4 tricarboxylic acid (PBTA) in the formation of hydroxyapatite (HA) was studied in vitro and in vivo. PBTA, at 4 ppm, inhibited the spontaneous formation of HA in vitro from a supersaturated solution. PBTA, at 2 ppm, completely inhibited the crystal growth of HA; at lo...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345850640011201
更新日期：1985-01-01 00:00:00
abstract：:Thermal diffusivity, a property related to the thermal insulative efficiency of a material, was measured in nine glass-ionomer cements and compared with results from a silicate and a polycarboxylate cement. Each cement was mixed at various powder-liquid ratios (P/L) and moulded into a rectangular prism of approximate ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345870660051001
更新日期：1987-05-01 00:00:00
abstract：:Attempts to produce resin composite with antibacterial properties by incorporation of an antibacterial agent such as chlorhexidine have been reported, but problems can arise due to release of the inhibitory agent from the composite. Such problems may include toxic effects, influence on mechanical properties, and loss ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345940730080701
更新日期：1994-08-01 00:00:00
abstract：:The field of dental materials has undergone more of a revolution than an evolution over the past 100 y. The development of new products, especially in the past half century, has occurred at a staggering pace, and their introduction to the market has been equally impressive. The movement has mostly come in the area of ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034518822808
更新日期：2019-03-01 00:00:00
