Abstract:
:During the polymerization of multifunctional monomers for dental restorations, typical final double-bond conversions range from 55 to 75%. The low conversion results in a large amount of extractable monomer, reduced adhesion to the filler, and the potential for increased swelling. In this work, the ability to increase the maximum conversion by optimizing the copolymer composition is explored. A series of multi-ethylene glycol dimethacrylate monomers of various lengths was used as a model system to determine how the copolymer composition affects the final conversion, the mechanical properties, and the predicted shrinkage. It was found that the ultimate conversion can be significantly increased, shrinkage decreased, and mechanical properties maintained. It was found that up to 30 wt% of poly(ethylene glycol) 600 dimethacrylate could be added to diethylene glycol dimethacrylate without reducing the strength and increasing the conversion. Results for other comonomer combinations were similar.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Anseth KS,Goodner MD,Reil MA,Kannurpatti AR,Newman SM,Bowman CNdoi
10.1177/00220345960750081301subject
Has Abstractpub_date
1996-08-01 00:00:00pages
1607-12issue
8eissn
0022-0345issn
1544-0591journal_volume
75pub_type
杂志文章abstract::The cartilaginous nasal septa of 28 albino rats were marked with pairs of wire implants. Measurements obtained from cephalometric radiographs taken at 30 and 60 days revealed that the implants invariably separatd and did so at a rate that was highly correlated with the growth of the rest of the snout. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590081601
更新日期:1980-08-01 00:00:00
abstract::The effect of a topical fluoride regimen consisting of a four-minute pre-treatment with a saturated dicalcium phosphate dihydrate (DCPD) solution followed by a four-minute application of APF was compared with that of a four-minute application of APF alone with respect to the deposition of fluoride in enamel in an apat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650030201
更新日期:1986-03-01 00:00:00
abstract::Although the tripeptides Glu-O-Phosphoserine-Tyr and Glu-O-Phosphoserine-Leu have been identified in embryonic bovine enamel proteins, 1, 2 the issue of whether both sequences occur in each of the phosphopeptides, or whether certain sequences occur in specific peptides only, has recently been resolved by isolating hom...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580023101
更新日期:1979-03-01 00:00:00
abstract::Known antimalarial compunds from several chemical classes were tested for their ability to inhibit in vitro growth of microorganisms causing dental plaque and to prevent the development of plaque in a hamster model. Approximately a third of the compounds tested inhibited in vitro growth; however, none prevented develo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345750540030901
更新日期:1975-05-01 00:00:00
abstract::The anticaries effect of professional fluoride (F) application has been attributed to calcium-fluoride-like deposits (CaF(2)) formed on enamel, but this has not been clearly demonstrated. We hypothesized that CaF(2) formed on plaque-free enamel by F application would reduce enamel demineralization due to the increase ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808701105
更新日期:2008-11-01 00:00:00
abstract::A frameshift mutation recently identified within the paired domain of the transcription factor, PAX9, has been linked to a unique form of oligodontia in a single, multigenerational family (Stockton et al., 2000). We now describe the phenotypic and segregation analyses of this remarkable kindred, the initial approach t...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790070701
更新日期:2000-07-01 00:00:00
abstract::Short-chain carboxylic acids (e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which can accumulate in the gingival crevice. It is of no small consequence, therefore, that 1- to 5-mM concentrations of these acids exhibit significant biological activity, including the a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760010801
更新日期:1997-01-01 00:00:00
abstract::Amylase activity in various tissues--i.e., submandibular/sublingual and parotid glands, the pancreas, saliva, and serum--in rats was measured after injection of isoproterenol, pilocarpine, and acetylcholine. All agents reduced amylase activity in the parotid gland and increased the enzyme activity in the submandibular...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620011201
更新日期:1983-01-01 00:00:00
abstract::This study contains the first part of a research project in which the applicability of fracture mechanics parameters to predict failure of a restored tooth was investigated. Fracture mechanics parameters have been used in dental research before, but were restricted to comparative studies between various brands of comp...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670060601
更新日期:1988-06-01 00:00:00
abstract::Erupting first permanent molars of 5 1/2 to 6 1/2 year-olds are eminently suited for the clinical testing of potential caries-inhibiting techniques. Due to the rapid onset of caries in these teeth, accurate monitoring of new materials/regimes can be instituted and meaningful data obtained within one year of trial comm...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/002203457705600301011
更新日期:1977-10-01 00:00:00
abstract::Morphogenesis (germ-tube formation) in Candida albicans was induced gratuitously by N-acetylhexosamine derivatives (N-acetyl-glucosamine covalently linked to agarose, N-acetylmannosamine, hyaluronic acid, colloidal chitin, and mucin). These compounds were not taken up by the yeast cells and did not support growth. 2-D...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630031501
更新日期:1984-03-01 00:00:00
abstract::The tongue exerts crucial functions in our daily life. However, we know very little about the regulatory mechanisms of mammalian tongue development. In this review, we summarize recent findings of the molecular and cellular mechanisms that control tissue-tissue interactions during tongue morphogenesis. Specifically, c...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034511434055
更新日期:2012-06-01 00:00:00
abstract::The goal of this study was to assess the ability of a scintillation camera method to detect areas of active bone loss due to periodontitis. Technetium 99m methylene diphosphonate was used as the bone-seeking radiopharmaceutical. Bone-seeking radiopharmaceutical uptake (BSRU) was imaged and quantified in alveolar bone ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345910700010801
更新日期:1991-01-01 00:00:00
abstract::It was recently reported that human periapical cysts (hPCys), a commonly occurring odontogenic cystic lesion of inflammatory origin, contain mesenchymal stem cells (MSCs) with the capacity for self-renewal and multilineage differentiation. In this study, periapical inflammatory cysts were compared with dental pulp to ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515570316
更新日期:2015-06-01 00:00:00
abstract::The fluid in and gingival tissue lining periodontal pockets were collected from male patients undergoing periodontal therapy. The collagenolytic activity of the crevicular fluid, and the ability of the gingiva in culture to degrade (a) an exogenous collagen substrate, and (b) endogenous collagen newly synthesized and ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580111601
更新日期:1979-11-01 00:00:00
abstract::A method of articulator comparison and a technique demonstrating the effects of three occlusal determinants were demonstrated and proved successful. The techniques used could be used in dental research circumstances and in dental schools as a means to study the determinants of occlusion. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550060601
更新日期:1976-11-01 00:00:00
abstract::Dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) are expressed as a single mRNA transcript coding for a large precursor protein termed dentin sialophosphoprotein (DSPP). DSP, DPP, and DSPP have been considered to be tooth-specific. To test for the expression of the dspp gene in bone, we performed Western immu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910208100607
更新日期:2002-06-01 00:00:00
abstract::Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in adults and occurs in about 50% of the US population. In addition to the clinical challenges associated with treating periodontitis, the pro...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515611876
更新日期:2016-02-01 00:00:00
abstract::Histone deacetylases (HDACs) are important regulators of gene expression that are aberrantly regulated in several inflammatory and infectious diseases. HDAC inhibitors (HDACi) suppress inflammatory activation of various cell types through epigenetic and non-epigenetic mechanisms, and ameliorate pathology in a mouse mo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034519885088
更新日期:2020-01-01 00:00:00
abstract::There is a large variability between and among individuals in the physiology of mastication, but it is not known whether this produces a similar variability in the particle sizes of food boluses at the end of the chewing process. Food boluses obtained just before swallowing were analyzed in ten subjects (aged 36.7 +/-...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/154405910408300713
更新日期:2004-07-01 00:00:00
abstract::Vitamin D, an anti-inflammatory mediator, has potential benefits for physical and oral health. Although it is produced endogenously, some individuals have a greater need for dietary and supplemental sources. This repeated-measures cross-sectional study assessed associations between total vitamin D intake and periodont...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513495239
更新日期:2013-08-01 00:00:00
abstract::Odontoblasts and fibroblasts are suspected to influence the innate immune response triggered in the dental pulp by micro-organisms that progressively invade the human tooth during the caries process. To determine whether they differ in their responses to oral pathogens, we performed a systematic comparative analysis o...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700304
更新日期:2008-03-01 00:00:00
abstract::The acquired enamel pellicle is an oral, fluid-derived protein layer that forms on the tooth surface. It is a biologically and clinically important integument that protects teeth against enamel demineralization, and abrasion. Tooth surfaces are exposed to different proteinaceous microenvironments depending on the enam...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516680771
更新日期:2017-04-01 00:00:00
abstract::Reporting the economic burden of oral diseases is important to evaluate the societal relevance of preventing and addressing oral diseases. In addition to treatment costs, there are indirect costs to consider, mainly in terms of productivity losses due to absenteeism from work. The purpose of the present study was to e...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515602879
更新日期:2015-10-01 00:00:00
abstract::The effect of combined administration of chlorhexidine and fluoride in the drinking water of hamsters on plaque and caries prevention was studied. Plaque indices of the hamsters receiving chlorhexidine either alone or simultaneously with fluoride were significantly lower than those of the control and fluoride only tre...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560111401
更新日期:1977-11-01 00:00:00
abstract::The main goal of peri-implantitis treatment is to control infection and arrest bone loss, which requires the removal of polymicrobial biofilms on the implant surface and the reduction of tissue invasion. Additionally, prognosis can be improved if reosseointegration occurs on previously contaminated implants. To evalua...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520913873
更新日期:2020-07-01 00:00:00
abstract::This study has identified and characterized class II (Ia) antigen-expressing cells in the normal rat incisor pulp by immunohistochemistry and flow cytometry. Two types of Ia-expressing cells occurred: one with a pronounced dendritic appearance located primarily in the periphery of the pulp, and one with morphological ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670100301
更新日期:1988-10-01 00:00:00
abstract::The uptake patterns of 90Sr in developing rat molar enamel were studied in vivo and in vitro. Autoradiographic methods were used that preclude loss or translocation of tracers associated with water-soluble compounds in the sections. In eight-day-old rats injected with the tracer, 90Sr uptake in the enamel was signific...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590121301
更新日期:1980-12-01 00:00:00
abstract::The inhibitory activity of 2-phosphono-butane 1,2,4 tricarboxylic acid (PBTA) in the formation of hydroxyapatite (HA) was studied in vitro and in vivo. PBTA, at 4 ppm, inhibited the spontaneous formation of HA in vitro from a supersaturated solution. PBTA, at 2 ppm, completely inhibited the crystal growth of HA; at lo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345850640011201
更新日期:1985-01-01 00:00:00
abstract::This randomized controlled trial aimed to evaluate the duration and outcome quality of orthodontic treatment with a customized fixed appliance system versus a noncustomized system. Patients ( n = 180) were randomized and received orthodontic treatment with the Insignia customized orthodontic system or the Damon Q nonc...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/0022034517720913
更新日期:2017-12-01 00:00:00