Abstract:
:Erupting first permanent molars of 5 1/2 to 6 1/2 year-olds are eminently suited for the clinical testing of potential caries-inhibiting techniques. Due to the rapid onset of caries in these teeth, accurate monitoring of new materials/regimes can be instituted and meaningful data obtained within one year of trial commencement. In addition, by concentrating on this age-group and by also stratifying for socio-economic status, deciduous caries experience and three-month wide age-bands, different trials' data can be readily compared. A further benefit is that these most caries-prone teeth can be protected thus saving the need for block injections in young subjects and alleviating later orthodontic problems.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Stephen KWdoi
10.1177/002203457705600301011subject
Has Abstractpub_date
1977-10-01 00:00:00pages
104-11eissn
0022-0345issn
1544-0591journal_volume
56 Spec Nopub_type
临床试验,杂志文章abstract::The acute effects of smokeless tobacco (ST) on buccal mucosal transport and barrier function were studied by means of in vivo and in vitro techniques. In humans, in vivo exposure to 0.5 g ST transiently increased the transmural electrical potential difference (PD). However, despite continued exposure, PD returned to b...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670111101
更新日期:1988-11-01 00:00:00
abstract::We have isolated a specific cell wall antigen of high molecular weight which appears to be unique to virulent strains of A viscosus and A naeslundii. The antigen is composed of two parts: a polysaccharide moiety containing 6-DOT as the major sugar and determinant of serologic specificity, and a small peptide bearing s...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/002203457605500111011
更新日期:1976-01-01 00:00:00
abstract::Intra-oral wounds, like wounds in children, demonstrate privileged healing when compared with adult wounds at extra-oral sites. This study investigated whether this preferential healing is related to an increased ability of oral mucosal fibroblasts to reorganize extracellular matrix (ECM) when compared with their derm...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750060601
更新日期:1996-06-01 00:00:00
abstract::Enamel abraders used in two-body wear tests suffer the disadvantage that standardization is difficult or impossible to obtain. The aim of this study was to test whether steatite (a ceramic material with a Vickers Hardness similar to that of enamel) could be used as a satisfactory human enamel analogue. The friction an...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345940730091001
更新日期:1994-09-01 00:00:00
abstract::Adenoviral vectors effectively transfer genes to rat salivary glands. However, potent immune responses limit their use in vivo. Mice offer more opportunities than rats for the study of these immune processes. We first established conditions for infection of mouse salivary glands, with an adenoviral vector. The effects...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790020201
更新日期:2000-02-01 00:00:00
abstract::The balance between bone resorption and bone formation is vital for maintenance and regeneration of alveolar bone and supporting structures around teeth and dental implants. Tissue regeneration in the oral cavity is regulated by multiple cell types, signaling mechanisms, and matrix interactions. A goal for periodontal...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034515618887
更新日期:2016-03-01 00:00:00
abstract::The discovery of the phenomenon "osseointegration," or functional ankylosis, has led to the development of oral implants with high clinical performance. Consequently, the placement of titanium implants has changed the paradigms of restorative dentistry. Implants are used to prevent placing reconstructions anchored on ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034519853574
更新日期:2019-11-01 00:00:00
abstract::The DMF index provides one source of information on past and present dental caries experience; however, important limitations hinder its ability to characterize fully the impact of dental caries. The purpose of this paper is to describe a measure of selected restoration and tooth conditions that supplements informatio...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/002203459607502S06
更新日期:1996-02-01 00:00:00
abstract::Eighteen different Streptococcus strains including S mutans, sanguis, mitis, salivarius, bovis, and 2F2, were assayed for their relative adsorption to synthetic hydroxyapatite and for quantities of lactic acid produced while in the adsorbed state. The results indicated that all S mutans and some S sanguis have an enha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560101401
更新日期:1977-10-01 00:00:00
abstract::Periodontal data typically consist of observations made at multiple sites within each patient. Observations within a patient tend to be positively correlated; hence, standard statistical techniques that assume independence are invalid. Regression techniques for correlated data have been proposed; communicating results...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200705
更新日期:2003-07-01 00:00:00
abstract::Genetic studies of early-onset periodontitis (EOP) are hampered by several factors. These include delayed onset of the trait, an upper age limit of expression of the disease, and lack of phenotypic information for edentulous family members. Segregation analyses of families with EOP support a major locus hypothesis but...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790031201
更新日期:2000-03-01 00:00:00
abstract::Limited cure depth is a drawback of light-activated composites. We hypothesize that curing light transmission and cure depth are influenced by monomer reactivity and filler/resin refractive index mismatch. Light transmission throughout cure was recorded for composites based on strontium (refractive index 1.51) or bari...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700115
更新日期:2008-01-01 00:00:00
abstract::This study investigated irregularities in hinge movement in 113 subjects. These irregularities were analyzed by computer with an instantaneous three-dimensional "screw axis method." The variation in hinge movement was measured by the dispersion of the hinge axis instant centers. Dispersion of instant centers was great...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610010301
更新日期:1982-01-01 00:00:00
abstract::Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in adults and occurs in about 50% of the US population. In addition to the clinical challenges associated with treating periodontitis, the pro...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515611876
更新日期:2016-02-01 00:00:00
abstract::The effects of various additives on the setting of the glass-ionomer cement system was studied by means of cone and plate viscometry. The action of (+)-tartaric acid, the most important additive, on the setting reaction depended on its concentration. Low concentrations accelerated the development of viscosity of the c...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670120101
更新日期:1988-12-01 00:00:00
abstract::When one uses composite resins, the curing contraction, the stiffness of the material, and the strength of the vulnerable dentinal bond are important factors in determining the marginal adaptation of the restoration. Calculations based on these intrinsic material properties have indicated that both bulk placement and ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670050901
更新日期:1988-05-01 00:00:00
abstract::Selected strains of oral bacteria were analyzed for their ability to degrade wheat starch, maltose, maltotriose, and maltoheptaose. S. sanguis IUOM-11M and JC804, S. mutans 6715, S. salivarius IUOM-8, A. viscosus IUOM-62, and A. naeslundii ATCC 12104 degraded all four substrates. S. mutans NCTC 10449 degraded starch, ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670011501
更新日期:1988-01-01 00:00:00
abstract::Incisors of Mg-deficient rats showed a marked inhibition of eruption and a decrease in mitoses of apical tissues. Cortisone administration resulted in some increase in eruption rate and cell division though these remained below the values of Mg-supplemented controls. An improvement in gross condition and a less severe...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560122901
更新日期:1977-12-01 00:00:00
abstract::Debonding rates of 164 resin-bonded prostheses (RBP) placed from 1974 to 1985 were examined at recall. The yearly debond rates were calculated, the cumulative probability of failure was determined for the debonded RBPs, and Weibull distribution parameters were determined. For perforated prostheses, there was a high in...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720081401
更新日期:1993-08-01 00:00:00
abstract::After cheek pouch carcinomas were induced in hamsters by the application of dimethylbenzanthracene (DMBA) to the right pouch for 13 weeks, the animals were divided into four groups and observed for seven more weeks. The control group received no further treatment, two experimental groups had incisional biopsies perfor...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650061401
更新日期:1986-06-01 00:00:00
abstract::Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially responsible for hybrid layer degradation. Since chlorhexidine inhibits MMPs, we hypothesized that chlorhexidine would decelerate the loss of resin-dentin bonds. Class I preparations in extracted th...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/154405910708600115
更新日期:2007-01-01 00:00:00
abstract::This paper aims to present a simple overview of potential new diagnostic methods for dental caries. There are several novel methods of caries detection (with potential application to diagnosis) which have been proposed in the last few years, in addition to those that are gaining some commercial exposure and clinical a...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/154405910408301s18
更新日期:2004-01-01 00:00:00
abstract::Mixtures containing two bacterial species were analyzed using flow cytometric techniques. Light scattering characteristics of Streptococcus mutans and Actinomyces viscosus show unique profiles for pure cultures. However, the light scatter analysis of a mixture containing these two species demonstrates overlapping near...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630080501
更新日期:1984-08-01 00:00:00
abstract::The adsorption isotherms of benzoic acid on synthetic hydroxyapatite (containing about 1.5 monolayers of physisorbed water) were studied from ethanol, dimethylsulfoxide, p-dioxane, methylene chloride, and benzene to discern the role of solvent in the process. The adsorption is reversible from the first three solvents ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650051601
更新日期:1986-05-01 00:00:00
abstract::In this study, we investigated whether selective activation of nociceptive primary afferent fibers by capsaicin would induce modulations on tooth-pulp-evoked sensory or inhibitory masseter reflex responses in healthy human subjects. The contribution of central N-methyl-D-aspartate (NMDA) receptor mechanisms in capsaic...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760090801
更新日期:1997-09-01 00:00:00
abstract::A gravity sintering fabrication technique has been developed for producing Co-Cr-Mo alloy dental implants having a porous coating on the root portion. This process allows for control of pore structure enabling ingrowth of either bone or fibrous tissue. The microstructure and mechanical properties of these materials ha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560050501
更新日期:1977-05-01 00:00:00
abstract::In this study, we sought to determine the association between tooth agenesis and DNA sequence variation in the genes MSX1 and PAX9 in an ethnically diverse human population. Since cleft lip/palate is also associated with both tooth agenesis and the gene TGFA, we included TGFA in the analysis as well. Cheek swab sample...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408300913
更新日期:2004-09-01 00:00:00
abstract::Class II major histocompatilibity complex (MHC)-expressing cells are usually distributed in dental pulp, and it was postulated that the colony-stimulating factor (CSF) derived from dental pulp fibroblasts contributes to the migration of class II MHC-expressing cells into pulp tissue. This study aimed to investigate th...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200204
更新日期:2003-02-01 00:00:00
abstract::A new hydroxyapatite ceramic implant material for restoration of atrophic edentulous ridges was tested in a canine animal model. The structure of this material is unique, in that it is produced from the skeleton of a coral, and in that it is penetrated by a uniform network of interconnected pores. Results indicate tha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620021301
更新日期:1983-02-01 00:00:00
abstract::The number of molars selected for prophylactic removal varies widely among general dental practitioners and oral surgeons. To understand the basis for such variations, we investigated two hypotheses: (1) Individual judgment strategies will differ concerning the use of cues (items of information), and (2) few dentists ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790121101
更新日期:2000-12-01 00:00:00