Degradation of starch and its hydrolytic products by oral bacteria.

abstract：:Gingiva from alloxan and streptozotocin-diabetic rats exhibited markedly enhanced collagenolytic activity in tissue culture. This effect was eliminated by puromycin or by repeated freeze-thawing of the tissue prior to incubation. Soluble extracts of the diabetic gingiva in situ were found to contain breakdown products...

journal_title：Journal of dental research

authors： Golub LM,Schneir M,Ramamurthy NS

更新日期：1978-03-01 00:00:00

abstract：:Because bone reconstruction in irradiated sites is less than ideal, we applied a regenerative gene therapy method in which a cell-signaling virus was localized to biomaterial scaffolds to regenerate wounds compromised by radiation therapy. Critical-sized defects were created in rat calvariae previously treated with ra...

journal_title：Journal of dental research

authors： Hu WW,Ward BB,Wang Z,Krebsbach PH

更新日期：2010-01-01 00:00:00

abstract：:Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects, HPP causes dental...

journal_title：Journal of dental research

authors： Foster BL,Sheen CR,Hatch NE,Liu J,Cory E,Narisawa S,Kiffer-Moreira T,Sah RL,Whyte MP,Somerman MJ,Millán JL

更新日期：2015-05-01 00:00:00

abstract：:The human mandibular condyle has a parasagittal plate-like trabecular structure. We tested the hypothesis that this structure reflects the mechanical loading of the condyle. We developed a finite element model of the condyle to analyze the strains occurring during static compressive loading. The principal strains in t...

journal_title：Journal of dental research

authors： van Ruijven LJ,Giesen EB,van Eijden TM

更新日期：2002-10-01 00:00:00

abstract：:Studies on mechanisms underlying the differentiation of dental pulp stem cells are critical for the understanding of the biology of odontogenesis and for dental tissue engineering. Here, we tested the hypothesis that stem cells from exfoliated deciduous teeth (SHED) differentiate into functional odontoblasts and endot...

journal_title：Journal of dental research

authors： Sakai VT,Zhang Z,Dong Z,Neiva KG,Machado MA,Shi S,Santos CF,Nör JE

更新日期：2010-08-01 00:00:00

abstract：:An adhesive opaque resin for veneering on cast metal was developed with 4-methacryloxyethyl trimellitate anhydride and poly (methyl methacrylate)-coated titanium dioxide prepared by aqueous phase polymerization. The opaque resin was a modified 4-META/MMA-TBB resin. The powder consisted of 20% of the encapsulated mater...

journal_title：Journal of dental research

authors： Matsumura H,Nakabayashi N

更新日期：1988-01-01 00:00:00

abstract：:Growing evidence suggests that individual genetic susceptibility may influence the host's response to infections. The aim of this project was to study whether gene polymorphisms of inflammatory markers are associated with the presence of viable periodontopathogenic bacteria. We extracted genomic DNA from 45 young adul...

journal_title：Journal of dental research

authors： Nibali L,Ready DR,Parkar M,Brett PM,Wilson M,Tonetti MS,Griffiths GS

更新日期：2007-05-01 00:00:00

abstract：:The effects of oral rinses on enamel fluoride uptake, caries, and plaque pH in rats were investigated by use of (1) an acidic calcium phosphate solution (CPS) saturated with dicalcium phosphate dihydrate (DCPD) and (2) a 1% fluoride solution. Osborne-Mendel rats, 19 days of age, were randomly assigned to one of four m...

journal_title：Journal of dental research

authors： Schreiber CT,Shern RJ,Chow LC,Kingman A

更新日期：1988-06-01 00:00:00

abstract：:Restriction endonuclease analysis (REA) was performed on the total cellular DNA from each of 396 strains of mutans streptococci (1) to determine its potential usefulness for the study of transmission of the organism and (2) to document the proportions and variety of strains harbored by members of a small group of fami...

journal_title：Journal of dental research

authors： Kulkarni GV,Chan KH,Sandham HJ

更新日期：1989-07-01 00:00:00

abstract：:Amelogenin gene organization varies from 6 exons (1,2,3,5,6,7) in amphibians and sauropsids to 10 in rodents. The additional exons are exons 4, 8, 9, and "4b", the latter being as yet unidentified in AMELX transcripts. To learn more about the evolutionary origin of these exons, we used an in silico approach to find th...

journal_title：Journal of dental research

authors： Sire JY,Huang Y,Li W,Delgado S,Goldberg M,Denbesten PK

更新日期：2012-01-01 00:00:00

abstract：:The pellicle serves as a multifunctional protective layer, providing, e.g., lubrication and remineralization and also acting as a diffusion barrier. In addition, since the formation of the pellicle precedes the adhesion of micro-organisms, it is also important as a conditioning film. We present a novel approach to stu...

journal_title：Journal of dental research

authors： Sotres J,Pettersson T,Lindh L,Arnebrant T

更新日期：2012-10-01 00:00:00

abstract：:It is shown that the creep behavior of a commercial dispersant-amalgam containing copper is improved by the addition of a manganese-containing alloy. This improvement is apparently obtained without any serious changes in corrosion resistance, provided that no more than 20% of the Mn alloy is added. ...

journal_title：Journal of dental research

authors： Waterstrat RM

更新日期：1978-09-01 00:00:00

abstract：:Using a hydraulic bellows system mounted on a maxillary partial denture, continuous force-displacement data were taken in an edentulous area in the maxillary bicuspid-molar region on ten adults. Both loading and unloading force-displacement curves showed three segments. Two visco-elastic properties - hysteresis and re...

journal_title：Journal of dental research

authors： Ho TP,Weinstein S,Bowley WW

更新日期：1984-10-01 00:00:00

abstract：:Bisphosphonates are a class of agents used to treat osteoporosis and malignant bone metastases. The efficacy of these agents in treating and preventing the significant skeletal complications associated with these conditions has had a major positive impact for patients and is responsible for their widespread use in med...

journal_title：Journal of dental research

authors： Ruggiero SL,Drew SJ

更新日期：2007-11-01 00:00:00

abstract：:The main purpose of this paper is to review the various methods used for evaluation of fluoride retention in saliva, plaque, and enamel following application of topical anti-caries treatments such as F dentifrices and F mouthwashes. Such methods monitor delivery of fluoride to the site of action, the mouth, and so can...

journal_title：Journal of dental research

authors： Duckworth RM,Gilbert RJ

更新日期：1992-04-01 00:00:00

abstract：:This study was undertaken in order to correlate the immune status of persons with various types of immune dysfunctions with the incidence of dental caries. Preliminary data on caries experience and the microbial composition of plaque in these individuals are presented. The findings suggest that persons with immunoglob...

journal_title：Journal of dental research

authors： Cole MF,Arnold RR,Rhodes MJ,McGhee JR

更新日期：1977-03-01 00:00:00

abstract：:Khat-chewing has been associated with oral lesions including oral cancer, but the mechanisms leading to their development are not known. We hypothesized that khat interferes with the physiological processes of the oral mucosa, such as cell proliferation and differentiation, and aimed at investigating the effects of kh...

journal_title：Journal of dental research

authors： Lukandu OM,Neppelberg E,Vintermyr OK,Johannessen AC,Costea DE

更新日期：2010-03-01 00:00:00

abstract：:The efficacy of a new remineralization system was determined in vivo by maintaining a low concentration of approximately 1 ppm fluoride for 48 hrs against a demineralized human tooth. Human subjects were selected who wore removable partial dentures containing two or more of the demineralized teeth with film system. Th...

journal_title：Journal of dental research

authors： Abrahams LJ,Yonese M,Higuchi WI,Fox JL,Charbeneau GT

更新日期：1980-03-01 00:00:00

abstract：:The biochemical function, adenylate energy charge (AEC), correlates with the viable count of S. mutans. AEC may be used to estimate the percent viable fraction of bacteria in dental plaque samples. An interactive computer program designed to process the AEC data is described. ...

journal_title：Journal of dental research

authors： Kemp CW

更新日期：1979-11-01 00:00:00

abstract：:The bactericidal effect of hexylresorcinol was assessed using bacterial aggregates. Increased drug concentration resulted in decreased survival of bacteria when the aggregates were exposed to hexylresorcinol for at least eight hours. This indicates that this drug may be effective against dental plaque only when availa...

journal_title：Journal of dental research

authors： Kraal JH,Hussain AA,Gregorio SB,Akaho E

更新日期：1979-11-01 00:00:00

abstract：:In mineralizing hamster molars, the influence of several inhibitors on p-NPP-ase has been demonstrated, and compared with their effect on PPi-ase, known to belong to the same enzyme. Whereas the latter activity is much more physiological, p-NPP is a better substrate to distinguish between the effects of bivalent catio...

journal_title：Journal of dental research

authors： Wöltgens JH

更新日期：1977-10-01 00:00:00

abstract：:The molecular mechanisms that maintain the equilibrium of odontoblast progenitor cells in dental pulp are unknown. Here we tested whether homeostasis in dental pulp is modulated by Twist-1, a nuclear protein that partners with Runx2 during osteoblast differentiation. Our analysis of Twist-1(+/-) mice revealed phenotyp...

journal_title：Journal of dental research

authors： Galler KM,Yasue A,Cavender AC,Bialek P,Karsenty G,D'Souza RN

更新日期：2007-10-01 00:00:00

abstract：:In a previous experiment, we found that masseter muscle spindles show functional plasticity after 5 to 15 days under increased occlusal vertical dimension (iOVD). In the present study, we hypothesized that spindle function would eventually recover if longer observation periods were allowed. Therefore, in this study we...

journal_title：Journal of dental research

authors： Yabushita T,Zeredo JL,Fujita K,Toda K,Soma K

更新日期：2006-09-01 00:00:00

abstract：:We determined the exposure to mercury from dental amalgam by comparison of blood levels of mercury before and after removal of all amalgams from ten subjects. Baseline concentrations of mercury in whole blood were measured weekly for four to 18 weeks (median = 6.6 weeks) prior to removal. All amalgams were removed in ...

journal_title：Journal of dental research

authors： Snapp KR,Boyer DB,Peterson LC,Svare CW

更新日期：1989-05-01 00:00:00

abstract：:The purpose of this study was to investigate the mechanism of surface layer formation in artificial white spots. Two nondestructive nuclear micro-analysis techniques were employed to analyze windows of human dental enamel at progressive stages of an artificial lesion. Fluoride concentrations were measured to a depth o...

journal_title：Journal of dental research

authors： Crawford AW,de Bruin HJ

更新日期：1983-09-01 00:00:00

abstract：:Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement of the periodontal ligament (PDL) space, and destruction of alveolar bone, leading to occlusal traumatism. We hypothesized that MS induces expression of osteoclastogenesis-associated chemok...

journal_title：Journal of dental research

authors： Goto KT,Kajiya H,Nemoto T,Tsutsumi T,Tsuzuki T,Sato H,Okabe K

更新日期：2011-06-01 00:00:00

abstract：:The benefits of early orthodontic treatment are continuously discussed, but studies are few. We examined whether definite need for orthodontic treatment could be eliminated in public health care by systematically focusing on early intervention. One age cohort living in a rural Finnish municipality (N = 85) was regular...

journal_title：Journal of dental research

authors： Kerosuo H,Väkiparta M,Nyström M,Heikinheimo K

更新日期：2008-06-01 00:00:00

abstract：:Much research has been devoted to the study of etched enamel, since it is critical to bonding. Currently, there are no precise data regarding the etched-enamel specific surface area. The aim of this study was to characterize, by two different methods, the surface of human dental enamel in vitro after being etched. It ...

journal_title：Journal of dental research

authors： Orellana MF,Nelson AE,Carey JP,Heo G,Boychuk DG,Major PW

更新日期：2008-06-01 00:00:00

abstract：:Frequent consumption of cariogenic foods and bacterial infection are risk factors for early childhood caries (ECC). This study hypothesized that a short diet survey focused on frequency of foods, categorized by putative cariogenicity, would differentiate severe ECC (S-ECC) from caries-free children. Children's diets w...

journal_title：Journal of dental research

authors： Palmer CA,Kent R Jr,Loo CY,Hughes CV,Stutius E,Pradhan N,Dahlan M,Kanasi E,Arevalo Vasquez SS,Tanner AC

更新日期：2010-11-01 00:00:00

abstract：:Since the exposure of mutans streptococci to xylitol is known to select for xylitol-resistant (XR) natural mutants, the occurrence and long-term survival of such xylitol-resistant strains was evaluated in a cross-sectional sampling of participants of the Ylivieska xylitol study four years after the original two-year e...

journal_title：Journal of dental research

authors： Trahan L,Söderling E,Dréan MF,Chevrier MC,Isokangas P

更新日期：1992-11-01 00:00:00