Clinical and genetic analysis of a large North European Caucasian family affected by early-onset periodontitis.

abstract：:With clinical oral examinations not always possible in health surveys, researchers may instead be invited to add questions to a wider health survey. In such situations, an item is needed which adequately represents both clinical and self-reported oral health. This study investigated the clinical validity of Locker's g...

journal_title：Journal of dental research

authors： Thomson WM,Mejia GC,Broadbent JM,Poulton R

更新日期：2012-11-01 00:00:00

abstract：:In this study, we sought to determine the association between tooth agenesis and DNA sequence variation in the genes MSX1 and PAX9 in an ethnically diverse human population. Since cleft lip/palate is also associated with both tooth agenesis and the gene TGFA, we included TGFA in the analysis as well. Cheek swab sample...

journal_title：Journal of dental research

authors： Vieira AR,Meira R,Modesto A,Murray JC

更新日期：2004-09-01 00:00:00

abstract：:This study investigated the association between caries status and sealant need at a prior survey and subsequent sealant use in a Medicaid program. Clinical data from a 1986-87 statewide epidemiological survey (N = 8026) representative of North Carolina (NC) schoolchildren (grades K-12) were linked with all NC Medicaid...

journal_title：Journal of dental research

authors： Robison VA,Rozier RG,Weintraub JA,Koch GG

更新日期：1997-12-01 00:00:00

abstract：:Stress-induced changes imparted in a 'dentin-bonded-crown' material during sintering, annealing, pre-cementation surface modification, and resin coating have been visualized by profilometry. The hypothesis tested was that operative techniques modify the stressing pattern throughout the material thickness. We polished ...

journal_title：Journal of dental research

authors： Isgró G,Addison O,Fleming GJ

更新日期：2010-01-01 00:00:00

abstract：:Significant inhibition of PMN metabolic activity by F- occurred at 0.1, 0.5 and 0.0 mM F- for O2- generation, 1-C14 CO2 release labeled glucose and NBT-reduction respectively. This inhibition resulted primarily from F- suppression of nonoxidative glucose metabolism. As the concentration of F- in the O2- generating sys...

journal_title：Journal of dental research

authors： Gabler WL,Leong PA

更新日期：1979-09-01 00:00:00

abstract：:Although it is known that diabetes impairs oral wound healing, relatively little is known about the cellular parameters affected, particularly in connective tissue. This study investigated the hypothesis that diabetes impairs connective tissue formation in healing gingiva, and that impaired healing is associated with ...

journal_title：Journal of dental research

authors： Desta T,Li J,Chino T,Graves DT

更新日期：2010-06-01 00:00:00

abstract：:Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...

journal_title：Journal of dental research

authors： Yamada S,Ozaki N,Tsushima K,Yamaba S,Fujihara C,Awata T,Sakashita H,Kajikawa T,Kitagaki J,Yamashita M,Yanagita M,Murakami S

更新日期：2016-08-01 00:00:00

abstract：:The purpose of this study was to evaluate the Bruxcore Plate (BP) as a dependent measure of nocturnal bruxing activity. As part of a bruxism treatment study, we evaluated 100 nocturnal bruxers for bruxing activity before, during, and immediately after treatment and again at a six-month recall. The first 40 subjects wo...

journal_title：Journal of dental research

authors： Pierce CJ,Gale EN

更新日期：1989-06-01 00:00:00

abstract：UNLABELLED:The aim of this cross-over, randomized, single-blinded trial was to examine whether intra-esophageal acidification induces sleep bruxism (SB). Polysomnography with electromyogram (EMG) of masseter muscle, audio-video recording, and esophageal pH monitoring were performed in a sleep laboratory. Twelve healthy...

journal_title：Journal of dental research

authors： Ohmure H,Oikawa K,Kanematsu K,Saito Y,Yamamoto T,Nagahama H,Tsubouchi H,Miyawaki S

更新日期：2011-05-01 00:00:00

abstract：:The whisker pad area (WP) is innervated by the second branch of the trigeminal nerve and experiences allodynia and hyperalgesia following transection of the mental nerve (MN; the third branch of the trigeminal nerve). However, the mechanisms of this extra-territorial pain remain unclear. The ionotropic P2X(7) ATP rece...

journal_title：Journal of dental research

authors： Murasaki K,Watanabe M,Takahashi K,Ito G,Suekawa Y,Inubushi T,Hirose N,Uchida T,Tanne K

更新日期：2013-03-01 00:00:00

abstract：:Local anesthetic agents may be classified according to their intrinsic anesthetic potency and duration of activity. Procaine and chloroprocaine are relatively weak, short-acting drugs. Lidocaine, mepivacaine, and prilocaine represent agents of intermediate potency and duration of action. Tetracaine, bupivacaine, and e...

journal_title：Journal of dental research

authors： Covino BG,Giddon DB

更新日期：1981-08-01 00:00:00

abstract：:The size of a bolus determines how it will be manipulated in the mouth and swallowed. We hypothesized that mucosal sensitivity would be important for masticatory function. The accuracy of solid object size perception, spatial acuity, and food particle size reduction during mastication were measured in 22 healthy adult...

journal_title：Journal of dental research

authors： Engelen L,van der Bilt A,Bosman F

更新日期：2004-05-01 00:00:00

abstract：:For practical reasons, evaluation of topical fluoride products must depend upon clinical and laboratory assessments. While not always a good predictor of clinical efficacy by itself, fluoride uptake is the most commonly used laboratory test. A consideration of the relationship between possible anticaries mechanisms of...

journal_title：Journal of dental research

authors： Mellberg JR

更新日期：1990-02-01 00:00:00

abstract：:Antigenic alterations to the dentin organic matrix may be detected by an immunohistochemical approach. We hypothesized that alterations in the antigenicity of type I collagen and proteoglycans occur in sclerotic dentin under caries lesions. Transverse sections were prepared from carious teeth in the sclerotic zone and...

journal_title：Journal of dental research

authors： Suppa P,Ruggeri A Jr,Tay FR,Prati C,Biasotto M,Falconi M,Pashley DH,Breschi L

更新日期：2006-02-01 00:00:00

abstract：:Wavelength-independent Microradiography (WIM), described in this paper, used polychromatic, high-energy (less than or equal to 60 kV) x-rays for determination of mineral concentrations in tooth material non-destructively. This was done with the aid of a reference step-wedge made of 94% aluminum, 6% zinc. The mass atte...

journal_title：Journal of dental research

authors： Herkströter FM,Ten Bosch JJ

更新日期：1990-08-01 00:00:00

abstract：:It has not been established whether transmission of mutans streptococci occurs between unrelated children older than 4 years of age. The aim of the study was to investigate the possible transmission of mutans streptococci genotypes from child to child in kindergarten. We studied 96 children (ages 5-6 yrs) in three San...

journal_title：Journal of dental research

authors： Doméjean S,Zhan L,DenBesten PK,Stamper J,Boyce WT,Featherstone JD

更新日期：2010-01-01 00:00:00

abstract：:The experiment was designed to determine the pathway taken to the brain stem by periodontal afferents responsible for the digastric jaw-opening reflex induced by tooth-tapping. Cutting the trigeminal sensory roots of anesthetized decerebrate cats eliminated the ipsilateral periodontally-induced reflex, although the st...

journal_title：Journal of dental research

authors： Collier TG,Lund JP

更新日期：1987-10-01 00:00:00

abstract：:The accumulated posteruptive tooth age was calculated for 212 children with Down's syndrome and 124 of their unaffected sibs. Posteruptive tooth age was shown to vary widely with different morphological permanent tooth types at the same chronological age. Girls in both groups had greater accumulated posteruptive tooth...

journal_title：Journal of dental research

authors： Orner G

更新日期：1975-05-01 00:00:00

abstract：:Pilocarpine (P) is of potential utility in the treatment of xerostomia. Because optimal development of P dosage forms for humans requires that its pharmacokinetics and pharmacodynamics be defined, this intravenous study of its disposition and associated salivary responses was performed. In a hospital setting, two heal...

journal_title：Journal of dental research

authors： Tanzer JM,Kramer PA,Schulman P,Willard AK

更新日期：1995-12-01 00:00:00

abstract：:The purpose of this study was to investigate the mechanism of surface layer formation in artificial white spots. Two nondestructive nuclear micro-analysis techniques were employed to analyze windows of human dental enamel at progressive stages of an artificial lesion. Fluoride concentrations were measured to a depth o...

journal_title：Journal of dental research

authors： Crawford AW,de Bruin HJ

更新日期：1983-09-01 00:00:00

abstract：:Adhesion of restorative and protective materials to dentin is an important requirement for operative and preventive dentistry. Wettability and roughness are dentin substrate conditions that are critical to establishing good adhesion. This study examined superficial and deep dentin for variations in water contact angle...

journal_title：Journal of dental research

authors： Rosales JI,Marshall GW,Marshall SJ,Watanabe LG,Toledano M,Cabrerizo MA,Osorio R

更新日期：1999-09-01 00:00:00

abstract：:Defined sets of transcriptional factors can reprogram human somatic cells to induced pluripotent stem (iPS) cells. However, many types of human cells are not easily accessible to minimally invasive procedures. Here we evaluated dental pulp cells (DPCs) as an optimal source of iPS cells, since they are easily obtained ...

journal_title：Journal of dental research

authors： Tamaoki N,Takahashi K,Tanaka T,Ichisaka T,Aoki H,Takeda-Kawaguchi T,Iida K,Kunisada T,Shibata T,Yamanaka S,Tezuka K

更新日期：2010-08-01 00:00:00

abstract：:In the rat parotid acinar cell, methacholine caused an increase in [Ca2+]i as determined by quin-2 fluorescence. The increase in [Ca2+]i was initially independent of, and subsequently dependent on, the presence of extracellular Ca2+, indicating mobilization of intracellular Ca2+, as well as activation of Ca2+ entry. M...

journal_title：Journal of dental research

authors： Aub DL,Putney JW Jr

更新日期：1987-02-01 00:00:00

abstract：:Temporomandibular joint (TMJ) disorders, including degenerative TMJ disease, occur primarily in women of reproductive age. Previous studies showed elevated estrogen levels in subjects with TMJ disorders relative to controls and the presence of estrogen receptors α and β (ERα and ERβ) in TMJ fibrocartilage. Additionall...

journal_title：Journal of dental research

authors： Ahmad N,Chen S,Wang W,Kapila S

更新日期：2018-08-01 00:00:00

abstract：:A procedure for measuring nasal airway resistance using posterior rhinorheometry is described. Baseline nasal airway resistances +/- 1 S.D. at an airflow of 0.5 L/sec were found to be 1.077 +/- 0.683 cm H2O for inhalation and 1.359 +/- 0.792 cm H2O for exhalation. Application of either cold water (4 to 6 C) or warm wa...

journal_title：Journal of dental research

authors： Martin JS,Tansy MF

更新日期：1977-11-01 00:00:00

abstract：:Jaw displacement tremor was investigated. Both tremor amplitude and tremor frequency were found to increase with increasing muscle activation. Co-contraction of jaw elevator and jaw depressor muscles was employed in order to vary muscle activation levels without the teeth being in occlusion. Reproducibility of tremor ...

journal_title：Journal of dental research

authors： McCarroll RS,De Vries JH

更新日期：1988-08-01 00:00:00

abstract：:This study's objective was to identify, in a statistically valid and efficient manner, the risk factors associated with dental implant failure. We hypothesize that factors exist which can be modified by clinicians to enhance outcome. A retrospective cohort study design was used. Cohort members had >or= one implant pla...

journal_title：Journal of dental research

authors： Chuang SK,Wei LJ,Douglass CW,Dodson TB

更新日期：2002-08-01 00:00:00

abstract：:The feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. Forty rhesus monkeys, Macaca mulatta, were used. Cariogenic streptococci, S mutans, were implanted into all the monkeys' mouths. There was no pathological effect resulting from immunization...

journal_title：Journal of dental research

authors： Bahn AN,Shklair IL,Hayashi JA

更新日期：1977-12-01 00:00:00

abstract：:Previous studies have clearly established the down-regulating effect of a sucrose-rich diet on primary dentinogenesis in rat molars. Earlier observation of the negative effect of a high-sucrose diet on a parotid function involved in the control of intradentinal solute movement led us to hypothesize that parotid gland ...

journal_title：Journal of dental research

authors： Leonora J,Tjäderhane L,Tieche JM

更新日期：2002-04-01 00:00:00

abstract：:Previous reports have linked the prevalence of tooth abnormalities with high caries experience in the different types of epidermolysis bullosa (EB). However, it is not known to what extent the apparent susceptibility to enamel caries is due to disease-related altered enamel chemistry in these cases. The aim of this st...

journal_title：Journal of dental research

authors： Kirkham J,Robinson C,Strafford SM,Shore RC,Bonass WA,Brookes SJ,Wright JT

更新日期：1996-09-01 00:00:00