Abstract:
UNLABELLED:The aim of this cross-over, randomized, single-blinded trial was to examine whether intra-esophageal acidification induces sleep bruxism (SB). Polysomnography with electromyogram (EMG) of masseter muscle, audio-video recording, and esophageal pH monitoring were performed in a sleep laboratory. Twelve healthy adult males without SB participated. Intra-esophageal infusions of 5-mL acidic solution (0.1 N HCl) or saline were administered. The frequencies of EMG bursts, rhythmic masticatory muscle activity (RMMA) episodes, grinding noise, and the RMMA/microarousal ratio were significantly higher in the 20-minute period after acidic infusion than after saline infusion. RMMA episodes including SB were induced by esophageal acidification. This trial is registered with the UMIN Clinical Trials Registry, UMIN000002923. ABBREVIATIONS:ASDA, American Sleep Disorders Association; EMG, electromyogram; GER, gastroesophageal reflux; LES, lower esophageal sphincter; NREM, non-rapid eye movement; REM, rapid eye movement; RMMA, rhythmic masticatory muscle activity; SB, sleep bruxism; SD, standard deviation; UES, upper esophageal sphincter.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Ohmure H,Oikawa K,Kanematsu K,Saito Y,Yamamoto T,Nagahama H,Tsubouchi H,Miyawaki Sdoi
10.1177/0022034510393516subject
Has Abstractpub_date
2011-05-01 00:00:00pages
665-71issue
5eissn
0022-0345issn
1544-0591pii
0022034510393516journal_volume
90pub_type
杂志文章,随机对照试验abstract::1. A method has been developed and described for obtaining accurate thermal diffusivity values for dental cements and other restorative materials. This method employs specimens of a short cylindrical geometry which are readily fabricated from simply-constructed molds. 2. Results obtained for polycarboxylate and glass-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600120801
更新日期:1981-12-01 00:00:00
abstract::The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740041001
更新日期:1995-04-01 00:00:00
abstract::Light propagation in human dentin exhibits a strong directional dependence featuring the long-known optical magnification property. We hypothesized that this anisotropic effect is caused by multiple scattering at the dentin tubules, and not by fiberoptic effects, as had been previously assumed. We performed measuremen...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608501017
更新日期:2006-10-01 00:00:00
abstract::Local anesthetic agents may be classified according to their intrinsic anesthetic potency and duration of activity. Procaine and chloroprocaine are relatively weak, short-acting drugs. Lidocaine, mepivacaine, and prilocaine represent agents of intermediate potency and duration of action. Tetracaine, bupivacaine, and e...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600080903
更新日期:1981-08-01 00:00:00
abstract::We have previously reported the clinical and radiographic findings of a trial in dogs of a new dental implant system after a functional period of eight months. The present report consists of the corresponding qualitative and quantitative histological data. The implant system was fabricated from Ti-6A1-4V and employed ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670090801
更新日期:1988-09-01 00:00:00
abstract::The relationship between the serum IgG antibody titer against seven species of Gram-negative periodontopathic bacteria and clinical parameters (including plaque index, gingival index, periodontal pocket depth, and alveolar bone loss) was studied in 38 subjects. IgG antibody titer against the sonicated antigens was det...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345850640111101
更新日期:1985-11-01 00:00:00
abstract::Greater fluoride concentrations were obtained in enamel treated with phosphate/fluoride solutions than in that treated with TiF4 at similar pH's (1.0) and F concentrations (0.6M F and 1.6M F). However, fluoride solution without added phosphate at pH 1.0 and 1.6M F concentration produced lower fluoride concentrations i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580021001
更新日期:1979-02-01 00:00:00
abstract::Amelogenin and ameloblastin, the major enamel matrix proteins, are important for enamel mineralization. To identify their synergistic roles in enamel development, we generated Amel X(-/-)/Ambn(-/-) mice. These mice showed additional enamel defects in comparison with Amel X(-/-) or Ambn(-/-) mice. In 7-day-old Amel X(-...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509334749
更新日期:2009-04-01 00:00:00
abstract::Inferior alveolar nerve (IAN) injury induces persistent ectopic pain which spreads to a wide area in the orofacial region. Its exact mechanism remains unclear. We investigated the involvement of nitric oxide (NO) in relation to ectopic orofacial pain caused by IAN transection (IANX). We assessed the changes in mechani...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513509280
更新日期:2013-12-01 00:00:00
abstract::Our observations confirm the previously reported observation that multinucleated cells develop within a two-week period in cat bone-marrow cultures. Calcitonin induces cytoplasmic contraction in these multinucleated cells, which indicates that they resemble osteoclasts. After seven days of culture, cat bone-marrow cul...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650070201
更新日期:1986-07-01 00:00:00
abstract::The effects of thermal stress on the marginal leakage of resin composite restorations in bovine teeth were investigated by a method that preserved the specimens. The changes in marginal leakage of specimens with increasing numbers of thermal cycles were measured by an electrical conductivity method. Four brands of pos...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345900690100601
更新日期:1990-10-01 00:00:00
abstract::The effect of toothbrushes on soft tissue abrasion was measured using hamster cheek pouch tissue brushed mechanically for various intervals. The detection of protein removed during brushing was used as an index of tissue abrasion. The method was found to be sensitive in detecting the effects of brush load, number of s...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560070301
更新日期:1977-07-01 00:00:00
abstract::Diabetes mellitus is associated with depression of natural defenses against infection and increases the risk of periodontal disease. However, the effects of diabetes on periradicular tissue, which differs structurally from periodontal tissue, are not known. In this study, we evaluated the effects of type 2 diabetes on...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200416
更新日期:2003-04-01 00:00:00
abstract::We evaluated the histopathological response of the periodontal membrane to intentionally-replanted teeth carrying composite (experimental) and silver amalgam (control) restorations in the middle third of each root. The study revealed that the amalgam produced, in the periodontal tissues, an initial localized inflammat...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620011801
更新日期:1983-01-01 00:00:00
abstract::Saliva plays a major role in maintaining oral health. Patients with salivary hypofunction exhibit difficulty in chewing and swallowing foods, tooth decay, periodontal disease, and microbial infections. At this time, treatments for hyposalivation are limited to medications (e.g., muscarinic receptor agonists: pilocarpi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515600157
更新日期:2015-11-01 00:00:00
abstract::Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516645796
更新日期:2016-08-01 00:00:00
abstract::In the absence of active pulmonary disease, mycobacterial infection frequently causes arthritis and can be considered to initiate autoimmune diseases such as rheumatoid arthritis. Temporomandibular disorder (TMD) is a disease in which pain and impaired mandibular movement appear to arise directly from degenerative or ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790100401
更新日期:2000-10-01 00:00:00
abstract::Pain and discomfort are common problems for patients undergoing orthodontic treatment. We have demonstrated that cortical excitation propagation in the somatosensory and insular cortices (IC) induced by electrical stimulation of the periodontal ligament (PDL) is facilitated 1 d after experimental tooth movement (ETM)....
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520962465
更新日期:2020-10-08 00:00:00
abstract::Fungal infections in the oral cavity are mainly caused by C. albicans, but other Candida species are also frequently identified. They are increasing in prevalence, especially in denture-wearers and aging people, and may lead to invasive infections, which have a high mortality rate. Attachment to mucosal tissues and to...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034508329273
更新日期:2009-02-01 00:00:00
abstract::Resin luting of all-ceramic restorations results in increased performance; however, the strengthening mechanism and the role of the mechanical properties of the resin are not fully understood. The hypothesis tested is that ceramic strength enhancement is dependent on the elastic modulus of the resin. Three-point flexu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600606
更新日期:2007-06-01 00:00:00
abstract::PAX9 is a transcription factor expressed in the tooth mesenchyme during tooth morphogenesis. In Pax9-null mice, tooth development is arrested at the bud stage. In humans, heterozygous mutations in PAX9 have been associated with non-syndromic tooth agenesis, predominantly in the molars. Here, we report 2 novel mutation...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513519801
更新日期:2014-03-01 00:00:00
abstract::Experiments were performed to determine the role of the immune response in rat periodontal disease. Germ-free rats were fed defined antigen-free liquid diets or a diet containing ovalbumin(OVA) as a prototype antigen. The OVA-fed rats demonstrated increased gingival lymphocytes (mainly T at early times), OVA-sensitize...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630031801
更新日期:1984-03-01 00:00:00
abstract::Mark Twain provides a humorous and insightful look into the origins of periodontal therapy and anesthesia in "Happy Memories of the Dental Chair". The main character of this story is Dr. John Riggs, the father of periodontics. Dr. Horace Wells, a pioneer in the field of anesthesia, also appears in the story. Twain pre...
journal_title:Journal of dental research
pub_type: 传,历史文章,杂志文章
doi:10.1177/0022034510366677
更新日期:2010-07-01 00:00:00
abstract::Interfacial bonding and stability of gamma-methacryloxypropyltrimethoxysilane with silica surfaces have been studied by means of infrared spectroscopy. The addition of n-propylamine enhances silanization of gamma-methacryloxypropyltrimethoxysilane to silica surfaces in normal aliphatic hydrocarbons, and cyclohexane yi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610121301
更新日期:1982-12-01 00:00:00
abstract::Twenty-two adults, considered to have high caries activity, rinsed for one yr with either SnF2 or acidulated NaF mouthrinses. Total colony-forming units and numbers of S. mutans and lactobacilli were estimated from saliva samples. Large reductions were found in the number of recoverable S. mutans in subjects rinsing w...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620081201
更新日期:1983-08-01 00:00:00
abstract::Adhesive bonding of resins to dentin surfaces requires the removal of the layer of debris caused by the cutting. Certain isotonic acidic solutions can do this rapidly. Five solutions were evaluated using cell cultures and pulp studies in monkeys. At concentrations above 10%, each solution caused the cultured human epi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610081001
更新日期:1982-08-01 00:00:00
abstract::Disks of dentin taken from extracted human teeth demonstrated the optical property of the magnification/reduction effect. When images were transmitted from a pulpal-to-occlusal direction, the images were magnified. When the disks were inverted, the images were reduced in size. The images were slightly distorted but cl...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550041601
更新日期:1976-07-01 00:00:00
abstract::Strength and durability of the dentin-acrylic resin joint cemented with 2-cyanoacrylate esters were studied. Maximum adhesion is obtained with isobutyl 2-cyanoacrylate after 1% acid pretreatment of the dentin. Hydrolytic stability is somewhat improved by addition of polymer to the adhesive or coating around the joint....
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580090901
更新日期:1979-09-01 00:00:00
abstract::The present study investigated a concept for additional cross-linking of dental polymers, by which resistance to wear of resin composites might be increased. Bifunctional ketones were added to monomer mixtures, which were then made light-curing and loaded with filler. The monomer mixtures were varied with respect to t...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345920710111601
更新日期:1992-11-01 00:00:00
abstract::We previously demonstrated that an anti-caries DNA vaccine intranasally administered with recombinant flagellin protein as a mucosal adjuvant enhanced salivary IgA response and conferred better protection against caries. However, the relatively weak immunogenicity of DNA vaccines and the necessity for a large quantity...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512457684
更新日期:2012-10-01 00:00:00