Influence of experimental esophageal acidification on sleep bruxism: a randomized trial.

Abstract:

UNLABELLED:The aim of this cross-over, randomized, single-blinded trial was to examine whether intra-esophageal acidification induces sleep bruxism (SB). Polysomnography with electromyogram (EMG) of masseter muscle, audio-video recording, and esophageal pH monitoring were performed in a sleep laboratory. Twelve healthy adult males without SB participated. Intra-esophageal infusions of 5-mL acidic solution (0.1 N HCl) or saline were administered. The frequencies of EMG bursts, rhythmic masticatory muscle activity (RMMA) episodes, grinding noise, and the RMMA/microarousal ratio were significantly higher in the 20-minute period after acidic infusion than after saline infusion. RMMA episodes including SB were induced by esophageal acidification. This trial is registered with the UMIN Clinical Trials Registry, UMIN000002923. ABBREVIATIONS:ASDA, American Sleep Disorders Association; EMG, electromyogram; GER, gastroesophageal reflux; LES, lower esophageal sphincter; NREM, non-rapid eye movement; REM, rapid eye movement; RMMA, rhythmic masticatory muscle activity; SB, sleep bruxism; SD, standard deviation; UES, upper esophageal sphincter.

journal_name

J Dent Res

authors

Ohmure H,Oikawa K,Kanematsu K,Saito Y,Yamamoto T,Nagahama H,Tsubouchi H,Miyawaki S

doi

10.1177/0022034510393516

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

665-71

issue

5

eissn

0022-0345

issn

1544-0591

pii

0022034510393516

journal_volume

90

pub_type

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