Effects of composite restorations on the periodontal membrane in monkeys.

abstract：:In cases of pulp exposure due to deep dental caries or severe traumatic injuries, existing pulp-capping materials have a limited ability to reconstruct dentin-pulp complexes and can result in pulpectomy because of their low potentials to accelerate dental pulp cell activities, such as migration, proliferation, and dif...

journal_title：Journal of dental research

authors： Yoshida S,Wada N,Hasegawa D,Miyaji H,Mitarai H,Tomokiyo A,Hamano S,Maeda H

更新日期：2016-10-01 00:00:00

abstract：:TWIST1 plays a crucial role in dentinogenesis, and its activity depends on both a dimerization partner selection and phosphorylation. Other factors, like Id proteins, can affect the availability of dimerization partners for TWIST1, subsequently leading to diverse biological outcomes. The purpose of this study was to e...

journal_title：Journal of dental research

authors： Maciejewska I,Sakowicz-Burkiewicz M,Pawelczyk T

更新日期：2014-06-01 00:00:00

abstract：:Purinergic signaling is involved in pain generation and modulation in the nociceptive sensory nervous system. Adenosine triphosphate (ATP) induces pain via activation of ionotropic P2X receptors while adenosine mediates analgesia via activation of metabotropic P1 receptors. These purinergic signaling are determined by...

journal_title：Journal of dental research

authors： Liu X,Ma L,Zhang S,Ren Y,Dirksen RT

更新日期：2017-06-01 00:00:00

abstract：:Cardiovascular disease is a common cause of morbidity and premature mortality. Cardiovascular disease can be prevented when risk factors are identified early. Calcified carotid artery atheromas (CCAAs), detected in panoramic radiographs, and periodontitis have both been associated with increased risk of cardiovascular...

journal_title：Journal of dental research

authors： Gustafsson N,Ahlqvist J,Näslund U,Buhlin K,Gustafsson A,Kjellström B,Klinge B,Rydén L,Levring Jäghagen E

更新日期：2020-01-01 00:00:00

abstract：:The discovery of the phenomenon "osseointegration," or functional ankylosis, has led to the development of oral implants with high clinical performance. Consequently, the placement of titanium implants has changed the paradigms of restorative dentistry. Implants are used to prevent placing reconstructions anchored on ...

journal_title：Journal of dental research

authors： Lang NP

更新日期：2019-11-01 00:00:00

abstract：:Inferior alveolar nerve (IAN) injury induces persistent ectopic pain which spreads to a wide area in the orofacial region. Its exact mechanism remains unclear. We investigated the involvement of nitric oxide (NO) in relation to ectopic orofacial pain caused by IAN transection (IANX). We assessed the changes in mechani...

journal_title：Journal of dental research

authors： Sugiyama T,Shinoda M,Watase T,Honda K,Ito R,Kaji K,Urata K,Lee J,Ohara K,Takahashi O,Echizenya S,Iwata K

更新日期：2013-12-01 00:00:00

abstract：:The bactericidal effect of hexylresorcinol was assessed using bacterial aggregates. Increased drug concentration resulted in decreased survival of bacteria when the aggregates were exposed to hexylresorcinol for at least eight hours. This indicates that this drug may be effective against dental plaque only when availa...

journal_title：Journal of dental research

authors： Kraal JH,Hussain AA,Gregorio SB,Akaho E

更新日期：1979-11-01 00:00:00

abstract：:To date, the precise etiology of molar-incisor hypomineralization (MIH) is uncertain. Vitamin D plays a key role in hard tissue formation. Therefore, this study aimed to analyze the relationship between serum 25-hydroxy-vitamin D (25(OH)D) status and dental health data obtained from 1,048 children in a 10-year follow-...

journal_title：Journal of dental research

authors： Kühnisch J,Thiering E,Kratzsch J,Heinrich-Weltzien R,Hickel R,Heinrich J,GINIplus study group.,LISAplus study group.

更新日期：2015-02-01 00:00:00

abstract：:The importance of assessing the impact of treatments for chronic conditions on an individual's quality of life has been well-established. In this randomized clinical trial, oral-health-related quality of life, measured with the Oral Health Impact Profile (OHIP), was compared between two groups of edentulous patients. ...

journal_title：Journal of dental research

authors： Awad MA,Locker D,Korner-Bitensky N,Feine JS

更新日期：2000-09-01 00:00:00

abstract：:Amelogenin and ameloblastin, the major enamel matrix proteins, are important for enamel mineralization. To identify their synergistic roles in enamel development, we generated Amel X(-/-)/Ambn(-/-) mice. These mice showed additional enamel defects in comparison with Amel X(-/-) or Ambn(-/-) mice. In 7-day-old Amel X(-...

journal_title：Journal of dental research

authors： Hatakeyama J,Fukumoto S,Nakamura T,Haruyama N,Suzuki S,Hatakeyama Y,Shum L,Gibson CW,Yamada Y,Kulkarni AB

更新日期：2009-04-01 00:00:00

abstract：:The recent bioengineering of complex tooth structures from pig tooth bud tissues suggests the potential for the regeneration of mammalian dental tissues. We have improved tooth bioengineering methods by comparing the utility of cultured rat tooth bud cells obtained from three- to seven-day post-natal (dpn) rats for to...

journal_title：Journal of dental research

authors： Duailibi MT,Duailibi SE,Young CS,Bartlett JD,Vacanti JP,Yelick PC

更新日期：2004-07-01 00:00:00

abstract：:Recent reports have suggested functional interactions between the masticatory and head motor systems. However, the neurophysiological mechanisms behind these phenomena have not been thoroughly investigated. In this study, the motor unit activity was recorded bilaterally from the dorsal neck splenius muscles (SPL) whil...

journal_title：Journal of dental research

authors： Zeredo JL,Toda K,Soma K

更新日期：2003-05-01 00:00:00

abstract：:The complexity of the periodontal microbiota resembles that of the gastro-intestinal tract, where infectious diseases are treatable via probiotics. In the oropharyngeal region, probiotic or replacement therapies have shown some benefit in the prevention of dental caries, otitis media, and pharyngitis, but their effect...

journal_title：Journal of dental research

authors： Teughels W,Newman MG,Coucke W,Haffajee AD,Van Der Mei HC,Haake SK,Schepers E,Cassiman JJ,Van Eldere J,van Steenberghe D,Quirynen M

更新日期：2007-11-01 00:00:00

abstract：:The inhibitory activity of 2-phosphono-butane 1,2,4 tricarboxylic acid (PBTA) in the formation of hydroxyapatite (HA) was studied in vitro and in vivo. PBTA, at 4 ppm, inhibited the spontaneous formation of HA in vitro from a supersaturated solution. PBTA, at 2 ppm, completely inhibited the crystal growth of HA; at lo...

journal_title：Journal of dental research

authors： Gaffar A,Moreno EC

更新日期：1985-01-01 00:00:00

abstract：:We have investigated the role of the activation of nuclear poly(ADP-ribose) polymerase (PARP) enzyme, a mediator of downstream nitric oxide toxicity, using a combined approach of pharmacological inhibition and genetic disruption in a ligature-induced-periodontitis model in rats and mice. Immunohistochemical analysis r...

journal_title：Journal of dental research

authors： Lohinai Z,Mabley JG,Fehér E,Marton A,Komjáti K,Szabó C

更新日期：2003-12-01 00:00:00

abstract：:Interleukin (IL)-23 is an essential cytokine involved in expansion of the Th17 lineage, which is associated with many immune-related destructive tissue diseases. We hypothesized that the IL-23-induced Th17 pathway plays a role in periodontal pathology and examined the expression of cytokines, and related molecules, in...

journal_title：Journal of dental research

authors： Ohyama H,Kato-Kogoe N,Kuhara A,Nishimura F,Nakasho K,Yamanegi K,Yamada N,Hata M,Yamane J,Terada N

更新日期：2009-07-01 00:00:00

abstract：:The fatigue crack growth resistance of dentin was characterized as a function of depth from the dentino-enamel junction. Compact tension (CT) specimens were prepared from the crowns of third molars in the deep, middle, and peripheral dentin. The microstructure was quantified in terms of the average tubule dimensions a...

journal_title：Journal of dental research

authors： Ivancik J,Neerchal NK,Romberg E,Arola D

更新日期：2011-08-01 00:00:00

abstract：:The eventual outcome of dental caries is determined by the dynamic balance between pathological factors that lead to demineralization and protective factors that lead to remineralization. Pathological factors include acidogenic bacteria, inhibition of salivary function, and frequency of ingestion of fermentable carboh...

journal_title：Journal of dental research

authors： Featherstone JD

更新日期：2004-01-01 00:00:00

abstract：:In an attempt to make a dynamic study of the isoelectric point and the chargeability of human dental enamel, an electrochemical approach was utilized. Zeta potential of three kinds of the enamel was measured by a streaming potential method. As a result, these isoelectric points could be decided. ...

journal_title：Journal of dental research

authors： Kambara M,Asai T,Kumasaki M,Konishi K

更新日期：1978-02-01 00:00:00

abstract：:The use of electric current during the application of etch-and-rinse adhesive systems has been recently claimed to increase bonding of etch-and-rinse adhesives by enhancing substrate impregnation. The null hypothesis tested in this study was that electrically assisted application has no effect on bond strength of self...

journal_title：Journal of dental research

authors： Breschi L,Mazzoni A,Pashley DH,Pasquantonio G,Ruggeri A,Suppa P,Mazzotti G,Di Lenarda R,Tay FR

更新日期：2006-12-01 00:00:00

abstract：:Angiogenesis and biomineral substrates play major roles in bone development and regeneration. We hypothesized that macroporous scaffolds of biomineralized 85:15 poly(lactide-co-glycolide), which locally release vascular endothelial growth factor-165 (VEGF), would direct simultaneous regeneration of bone and vascular t...

journal_title：Journal of dental research

authors： Murphy WL,Simmons CA,Kaigler D,Mooney DJ

更新日期：2004-03-01 00:00:00

abstract：:Several studies indicated that serotype/biotype c strains are the most common on a global basis, but that regional differences may occur relative to other serotype/biotypes. Of particular interest is the observation that individuals residing in the Middle East have higher incidences of serotype e and d strains relativ...

journal_title：Journal of dental research

authors： Farghaly MM,Eklund S,Loesche WJ

更新日期：1984-01-01 00:00:00

abstract：:During the maintenance of bone marrow-derived mesenchymal stem cells (BMMSCs), suspended cells are discarded normally. We noted the osteogenic potential of these cells to be like that of anchorage-dependent BMMSCs. Therefore, we characterized suspended BMMSCs from rabbit bone marrow by bioengineering and applied the s...

journal_title：Journal of dental research

authors： Zheng RC,Park YK,Cho JJ,Kim SK,Heo SJ,Koak JY,Lee JH

更新日期：2014-10-01 00:00:00

abstract：:Interfacial bond strengths of light-activated composites were measured as a function of age using a transverse strength test. Bond strength between layers decreased with the age of the initial layer and reflected the setting curves of the composites. The highly-filled composites exhibited the greatest bond strengths. ...

journal_title：Journal of dental research

authors： Boyer DB,Chan KC,Reinhardt JW

更新日期：1984-10-01 00:00:00

abstract：:Studies on mechanisms underlying the differentiation of dental pulp stem cells are critical for the understanding of the biology of odontogenesis and for dental tissue engineering. Here, we tested the hypothesis that stem cells from exfoliated deciduous teeth (SHED) differentiate into functional odontoblasts and endot...

journal_title：Journal of dental research

authors： Sakai VT,Zhang Z,Dong Z,Neiva KG,Machado MA,Shi S,Santos CF,Nör JE

更新日期：2010-08-01 00:00:00

abstract：:We have isolated a specific cell wall antigen of high molecular weight which appears to be unique to virulent strains of A viscosus and A naeslundii. The antigen is composed of two parts: a polysaccharide moiety containing 6-DOT as the major sugar and determinant of serologic specificity, and a small peptide bearing s...

journal_title：Journal of dental research

authors： Hammond BF,Steel CF,Peindl KS

更新日期：1976-01-01 00:00:00

abstract：:The temporal and spatial patterns in which teeth are initiated in the growing jaws of embryos are constant for a species but different for different species. The sources of the patterns have been explained in two ways. First, they are the outcome of reactions between molecules created at stationary targets and those w...

journal_title：Journal of dental research

authors： Osborn JW

更新日期：1998-09-01 00:00:00

abstract：:Significant differences exist between human and Macaca fascicularis patterns of mandibular movement during mastication. Macaque patterns display less asymmetry, more uniformity, and limited lateral excursions when compared to humans for mastication of the same food. Different anatomical structures between the two spec...

journal_title：Journal of dental research

authors： Byrd KE,Milberg DJ,Luschei ES

更新日期：1978-07-01 00:00:00

abstract：:This 24-mo randomized controlled trial was based on a double-blind parallel design, and it compared the effectiveness of 2 fluoride application protocols in arresting dentine caries in primary teeth. Three-year-old children with active dentine caries were recruited and randomly allocated to 2 treatment groups. Childre...

journal_title：Journal of dental research

authors： Chen KJ,Gao SS,Duangthip D,Lo ECM,Chu CH

更新日期：2021-01-01 00:00:00

abstract：:The aim of this study was to determine whether the parotid gland, like other salivary glands, produces blood group antigens. A post-embedding immunogold staining (IGS) method for ABH antigens was applied to osmicated and nonosmicated, routinely prepared specimens of normal human parotid glands. A and B antigens were n...

journal_title：Journal of dental research

authors： Lantini MS,Cossu M

更新日期：1994-02-01 00:00:00