Abstract：
:To date, the precise etiology of molar-incisor hypomineralization (MIH) is uncertain. Vitamin D plays a key role in hard tissue formation. Therefore, this study aimed to analyze the relationship between serum 25-hydroxy-vitamin D (25(OH)D) status and dental health data obtained from 1,048 children in a 10-year follow-up of the Munich GINIplus and LISAplus birth cohorts. The dental examination included the diagnosis of MIH and recording of (non-)cavitated caries lesions in primary and permanent teeth. Serum 25(OH)D concentrations were taken from blood samples of the 10-year investigation and measured with a fully automated, modular system. Different logistic regression and Poisson hurdle models were calculated. MIH was diagnosed in 13.6% of the study population. Approximately 16.4% of the children demonstrated caries-related defects (D3-4MFS > 0). The mean season-adjusted concentration of 25(OH)D was 75.8 nmol/l (standard deviation 22.0 nmol/l). After adjusting for sex, age, body mass index, parental education, equivalent income, and television/personal computer (TV/PC) viewing hours, a 10 nmol/l increase in serum 25(OH)D concentrations was significantly associated with a lower odds ratio of having MIH (OR = 0.89; P = 0.006). Furthermore, higher 25(OH)D values were associated with a lower number of caries-affected permanent teeth. It is concluded that elevated serum 25(OH)D concentrations were associated with better dental health parameters.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Kühnisch J,Thiering E,Kratzsch J,Heinrich-Weltzien R,Hickel R,Heinrich J,GINIplus study group.,LISAplus study group.doi
10.1177/0022034514561657subject
Has Abstractpub_date
2015-02-01 00:00:00pages
381-7issue
2eissn
0022-0345issn
1544-0591pii
0022034514561657journal_volume
94pub_type
杂志文章abstract：:Mutations and common polymorphisms in interferon regulatory factor 6 ( IRF6) are associated with both syndromic and nonsyndromic forms of cleft lip/palate (CLP). To date, much of the focus on this transcription factor has been on identifying its direct targets and the gene regulatory network in which it operates. Nota...
journal_title：Journal of dental research
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abstract：:An acidified gel system was used to produce artificial caries lesions in root surfaces. Radiopaque surface layers were found with 47% of the lesions. Demineralized bodies of the lesion and mineralized zones of banding were seen in all lesions when examined by microradiography. Cementum and dentin seemed to respond to ...
journal_title：Journal of dental research
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doi：10.1177/00220345850640050401
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abstract：:A simple in vitro method has been described for quantitatively measuring the rate at which isotopically labeled substances permeate through dentin in occlusal cavity preparations. The presence or absence of pulp tissue had only a minor effect on the kinetics of permeation. As the dentin was made thinner there was a re...
journal_title：Journal of dental research
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abstract：:Although pulp fibroblasts are a major cell type in dental pulp, their roles in microbial recognition and pulpal inflammation are not well-understood. Considering the pivotal role of Toll-like receptors (TLRs) in the recognition of micro-organisms, we hypothesized that TLRs on pulp fibroblasts may induce inflammatory s...
journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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更新日期：1981-02-01 00:00:00
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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更新日期：1987-12-01 00:00:00
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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doi：10.1177/00220345830620060501
更新日期：1983-06-01 00:00:00
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journal_title：Journal of dental research
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doi：10.1177/00220345000790081101
更新日期：2000-08-01 00:00:00
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journal_title：Journal of dental research
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更新日期：1976-09-01 00:00:00
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journal_title：Journal of dental research
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更新日期：1978-03-01 00:00:00
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journal_title：Journal of dental research
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doi：10.1177/00220345960750021301
更新日期：1996-02-01 00:00:00
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journal_title：Journal of dental research
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doi：10.1177/00220345840630101501
更新日期：1984-10-01 00:00:00
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journal_title：Journal of dental research
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更新日期：1993-01-01 00:00:00
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journal_title：Journal of dental research
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更新日期：2015-05-01 00:00:00
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journal_title：Journal of dental research
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更新日期：2012-02-01 00:00:00
abstract：:Three dental amalgams were investigated to determine if their abrasion resistance was significantly affected by different packing pressures. Abrasive wear tests were performed on a machine designed to test materials under conditions similar to masticatory function. The results show that the abrasion resistance of the ...
journal_title：Journal of dental research
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更新日期：1977-06-01 00:00:00
abstract：:A model system consisting of vacuum-deposited aluminum on glass was developed to demonstrate the effectiveness of cavitational activity (occurring within the cooling water supply of a dental ultrasonic scaler) in the removal of particulate material from solid surfaces. The amount of solid material removed from the mod...
journal_title：Journal of dental research
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更新日期：1984-09-01 00:00:00
abstract：:Sensory, sympathetic and parasympathetic ganglia located in the head and neck of rhesus monkeys were histologically examined after injection of H3-HRP into the right mandibular premolars and molars. The results showed positive labeling of ganglionic cell bodies located in the ipsilateral trigeminal, superior cervical,...
journal_title：Journal of dental research
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更新日期：1980-04-01 00:00:00
abstract：:Reporting the economic burden of oral diseases is important to evaluate the societal relevance of preventing and addressing oral diseases. In addition to treatment costs, there are indirect costs to consider, mainly in terms of productivity losses due to absenteeism from work. The purpose of the present study was to e...
journal_title：Journal of dental research
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更新日期：2015-10-01 00:00:00
abstract：:The number of molars selected for prophylactic removal varies widely among general dental practitioners and oral surgeons. To understand the basis for such variations, we investigated two hypotheses: (1) Individual judgment strategies will differ concerning the use of cues (items of information), and (2) few dentists ...
journal_title：Journal of dental research
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doi：10.1177/00220345000790121101
更新日期：2000-12-01 00:00:00
abstract：:Dental enamel formation is a remarkable example of a biomineralization process. The exact mechanisms involved in this process remain partly obscure. Some of the genes encoding specific enamel proteins have been indicated as candidate genes for amelogenesis imperfecta. Mutational analyses within studied families have s...
journal_title：Journal of dental research
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doi：10.1177/154405910508401206
更新日期：2005-12-01 00:00:00
