Histopathology of the initial lesion of the root surface: an in vitro study.

abstract：:The experiment was designed to determine the pathway taken to the brain stem by periodontal afferents responsible for the digastric jaw-opening reflex induced by tooth-tapping. Cutting the trigeminal sensory roots of anesthetized decerebrate cats eliminated the ipsilateral periodontally-induced reflex, although the st...

journal_title：Journal of dental research

authors： Collier TG,Lund JP

更新日期：1987-10-01 00:00:00

abstract：:The Wingless/integrase-1 (Wnt) family of protein ligands and their functional antagonists, secreted frizzled-related proteins (sFRPs), regulate various biological processes ranging from embryonic development to immunity and inflammation. Wnt5a and sFRP5 comprise a typical ligand/antagonist pair, and the former molecul...

journal_title：Journal of dental research

authors： Maekawa T,Kulwattanaporn P,Hosur K,Domon H,Oda M,Terao Y,Maeda T,Hajishengallis G

更新日期：2017-05-01 00:00:00

abstract：:The expression of antimicrobial peptides at epithelial surfaces such as skin, lung, and intestine is thought to provide protection against infection. Cathelicidin antimicrobial peptides are essential for the protection of skin against invasive bacterial infection. To determine if cathelicidins are also present in the ...

journal_title：Journal of dental research

authors： Murakami M,Ohtake T,Dorschner RA,Gallo RL

更新日期：2002-12-01 00:00:00

abstract：:In comparison with control rats. chronic administration of isoproterenol (IPR) caused enlargement of the parotid and submandibular glands and the synthesis of apparently new proteins, probably by acinar cells. The parotid and submandibular saliva secreted in response to methoxamine or IPR differed markedly in protein ...

journal_title：Journal of dental research

authors： Abe K,Dawes C

更新日期：1980-06-01 00:00:00

abstract：:The dentition in zebrafish is extremely and richly vascularized, but the function of the vasculature, in view of the continuous replacement of the teeth, remains elusive. Through application of SU5416, a vascular endothelial growth factor receptor inhibitor, we studied the role of the blood vessels in the dentition of...

journal_title：Journal of dental research

authors： Crucke J,Huysseune A

更新日期：2015-01-01 00:00:00

abstract：:With the objective of contributing to the understanding of factors influencing the characteristics of dentition, dental observations from 429 children and adult highland people of western Bolivia are described. Various age, sex, ethnic, and village differences are observed in malocclusion, dental caries, periodontal d...

journal_title：Journal of dental research

authors： Palomino H

更新日期：1978-03-01 00:00:00

abstract：:The use of electric current during the application of etch-and-rinse adhesive systems has been recently claimed to increase bonding of etch-and-rinse adhesives by enhancing substrate impregnation. The null hypothesis tested in this study was that electrically assisted application has no effect on bond strength of self...

journal_title：Journal of dental research

authors： Breschi L,Mazzoni A,Pashley DH,Pasquantonio G,Ruggeri A,Suppa P,Mazzotti G,Di Lenarda R,Tay FR

更新日期：2006-12-01 00:00:00

abstract：:Although little is known about the mechanism of action of eugenol, some related compounds have been compared with capsaicin derivatives in terms of the relationship between their chemical structure and activity. To elucidate whether eugenol and capsaicin act via a common mechanism at the neuronal membrane, we investig...

journal_title：Journal of dental research

authors： Ohkubo T,Kitamura K

更新日期：1997-11-01 00:00:00

abstract：:Recent functional animal studies have reported that the motor control of masticatory muscle function is bilaterally guided by both hemispheres, which may fundamentally differ from the cortical control of limb muscle function. In this study, we investigated whether unilateral cortical brain infarction induces different...

journal_title：Journal of dental research

authors： Kemppainen P,Waltimo A,Palomäki H,Salonen O,Könönen M,Kaste M

更新日期：1999-12-01 00:00:00

abstract：:Since Thewlis found the "two fiber axes" patterns on x-ray diffractograms of human enamel in 1934, many investigators have studied this problem. However, a definite answer has not yet been obtained. The present detailed x-ray diffraction study showed that the "two fiber axes" patterns in human enamel were caused by re...

journal_title：Journal of dental research

authors： Hirota F

更新日期：1986-07-01 00:00:00

abstract：:Loss of hybrid layer integrity compromises resin-dentin bond stability. Matrix metalloproteinases (MMPs) may be partially responsible for hybrid layer degradation. Since chlorhexidine inhibits MMPs, we hypothesized that chlorhexidine would decelerate the loss of resin-dentin bonds. Class I preparations in extracted th...

journal_title：Journal of dental research

authors： Carrilho MR,Carvalho RM,de Goes MF,di Hipólito V,Geraldeli S,Tay FR,Pashley DH,Tjäderhane L

更新日期：2007-01-01 00:00:00

abstract：:Chondroitin sulfate is up-regulated in granulation tissue during wound healing. To investigate the role of chondroitin sulfate in the wound-healing process after surgical repair of cleft palate, we isolated and cultured rabbit palatal fibroblasts. Treatment with chondroitin-6-sulfate resulted in a dose-dependent incre...

journal_title：Journal of dental research

authors： Zou XH,Foong WC,Cao T,Bay BH,Ouyang HW,Yip GW

更新日期：2004-11-01 00:00:00

abstract：:Investigators have used chemotherapeutic agents topically for plaque control without knowing the drug concentration necessary to inhibit the growth of odontopathic microorganisms. S mutans, S sanguis, A viscosus and A naeslundii are important components of the plaque flora. The minimal inhibitory concentrations (MIC) ...

journal_title：Journal of dental research

authors： Newbrun E,Felton RA,Bulkacz J

更新日期：1976-07-01 00:00:00

abstract：:Debonding rates of 164 resin-bonded prostheses (RBP) placed from 1974 to 1985 were examined at recall. The yearly debond rates were calculated, the cumulative probability of failure was determined for the debonded RBPs, and Weibull distribution parameters were determined. For perforated prostheses, there was a high in...

journal_title：Journal of dental research

authors： Boyer DB,Williams VD,Thayer KE,Denehy GE,Diaz-Arnold AM

更新日期：1993-08-01 00:00:00

abstract：:An in vitro model has been developed for measurement of initial attachment of 3H-labeled human gingival fibroblasts (HGF) and periodontal ligament cells (HPDL cells) to sieved dentin powder. Reproducible attachment was obtained and was closely related to the number of plated cells, the amount of dentin powder, the tem...

journal_title：Journal of dental research

authors： Rompen EH,Kohl J,Nusgens B,Lapiere CM

更新日期：1993-03-01 00:00:00

abstract：:The purpose of this study was to investigate the genotoxic effects of chronic fluoride exposure on mammalian cells in vivo by use of the mouse bone-marrow micronucleus test and the sperm morphology methodology. Mice of genotype B6C3F1 were obtained at weaning and maintained on a low-fluoride diet (less than 0.2 ppm F)...

journal_title：Journal of dental research

authors： Dunipace AJ,Zhang W,Noblitt TW,Li Y,Stookey GK

更新日期：1989-11-01 00:00:00

abstract：:The recent bioengineering of complex tooth structures from pig tooth bud tissues suggests the potential for the regeneration of mammalian dental tissues. We have improved tooth bioengineering methods by comparing the utility of cultured rat tooth bud cells obtained from three- to seven-day post-natal (dpn) rats for to...

journal_title：Journal of dental research

authors： Duailibi MT,Duailibi SE,Young CS,Bartlett JD,Vacanti JP,Yelick PC

更新日期：2004-07-01 00:00:00

abstract：:Caries of the permanent first molars of 5-year-old children was found to be associated with caries of their diciduous teeth. The sample consisted of 220 children whose permanent first molars had erupted. They were selected out of 965 children who were a representative sample of children attending compulsory kindergart...

journal_title：Journal of dental research

authors： Zadik D

更新日期：1976-11-01 00:00:00

abstract：:Class II major histocompatilibity complex (MHC)-expressing cells are usually distributed in dental pulp, and it was postulated that the colony-stimulating factor (CSF) derived from dental pulp fibroblasts contributes to the migration of class II MHC-expressing cells into pulp tissue. This study aimed to investigate th...

journal_title：Journal of dental research

authors： Sawa Y,Horie Y,Yamaoka Y,Ebata N,Kim T,Yoshida S

更新日期：2003-02-01 00:00:00

abstract：:We explored the potential to diagnose Zika virus (ZIKV) infection by analyzing peptides in saliva during a convalescent phase of infection, long after resolution of acute disease. A 25-y-old woman clinically diagnosed with Zika fever in the first trimester was enrolled with her dizygotic twins for a 3-mo postnatal sam...

journal_title：Journal of dental research

authors： Zuanazzi D,Arts EJ,Jorge PK,Mulyar Y,Gibson R,Xiao Y,Bringel Dos Santos M,Machado MAAM,Siqueira WL

更新日期：2017-09-01 00:00:00

abstract：:Medication-related osteonecrosis of the jaw (MRONJ), although initially believed to be exclusively associated with bisphosphonates, has been implicated in recent reports with additional drugs, especially the bone antiresorptive denosumab. The pathophysiology has not been fully elucidated, and no causal association bet...

journal_title：Journal of dental research

authors： Katsarelis H,Shah NP,Dhariwal DK,Pazianas M

更新日期：2015-04-01 00:00:00

abstract：:Stem cells are remarkable, and stem cell-based tissue engineering is an emerging field of biomedical science aiming to restore damaged tissue or organs. In dentistry and reconstructive facial surgery, it is of great interest to restore lost teeth or craniofacial bone defects using stem cell-mediated therapy. In the cr...

journal_title：Journal of dental research

authors： Zhao H,Chai Y

更新日期：2015-11-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) plays a crucial role in the modulation of orofacial pain, and we hypothesized that CGRP mediated a neuron-glia crosstalk in orofacial pain. The objective of this study was to elucidate the mechanisms whereby CGRP mediated trigeminal neuron-glia crosstalk in modulating orofacial p...

journal_title：Journal of dental research

authors： Liang H,Hu H,Shan D,Lyu J,Yan X,Wang Y,Jian F,Li X,Lai W,Long H

更新日期：2021-01-01 00:00:00

abstract：:The main purpose of this paper is to review the various methods used for evaluation of fluoride retention in saliva, plaque, and enamel following application of topical anti-caries treatments such as F dentifrices and F mouthwashes. Such methods monitor delivery of fluoride to the site of action, the mouth, and so can...

journal_title：Journal of dental research

authors： Duckworth RM,Gilbert RJ

更新日期：1992-04-01 00:00:00

abstract：:Enamel demineralization adjacent to pit and fissure sealants leads to the formation of marginal caries, which can necessitate the replacement of existing sealants. Dental materials with bioactive glass, which releases ions that inhibit dental caries, have been studied. The purpose of this study was to evaluate the ena...

journal_title：Journal of dental research

authors： Yang SY,Kwon JS,Kim KN,Kim KM

更新日期：2016-05-01 00:00:00

abstract：:Hydrogen sulfide (H2S) and methyl mercaptan (CH3SH) are the volatile sulfur compounds (VSC) that were investigated for a possible role in the etiology of periodontal disease. The results show that the permeability of porcine non-keratinized sublingual mucosa is increased by up to 75% or 103% following exposure to H2S ...

journal_title：Journal of dental research

authors： Ng W,Tonzetich J

更新日期：1984-07-01 00:00:00

abstract：:Mechanical removal of oral biofilms is ubiquitously accepted as the best way to prevent caries and periodontal diseases. Removal effectiveness strongly depends on biofilm strength. To investigate the influence of hydrodynamics on oral biofilm strength, we grew single- and multi-species biofilms of Streptococcus oralis...

journal_title：Journal of dental research

authors： Paramonova E,Kalmykowa OJ,van der Mei HC,Busscher HJ,Sharma PK

更新日期：2009-10-01 00:00:00

abstract：:4-META and new phosphate-methacrylate resins adhere strongly to dental alloys. However, for strengthening the water durability of the adhesive interface, the oxidation of the alloy surface is indispensable. A new oxidation method using ion-sputtering was developed, and the effectiveness of this surface treatment on tw...

journal_title：Journal of dental research

authors： Tanaka T,Hirano M,Kawahara M,Matsumura H,Atsuta M

更新日期：1988-11-01 00:00:00

abstract：:Epstein-Barr virus (EBV), in addition to its transforming properties, contributes to the pathogenesis of several inflammatory diseases. Here, we investigated its involvement in oral lichen planus (OLP), a common autoimmune-like disease of unknown etiopathogenesis that can display a malignant potential. EBV-infected ce...

journal_title：Journal of dental research

authors： Raybaud H,Olivieri CV,Lupi-Pegurier L,Pagnotta S,Marsault R,Cardot-Leccia N,Doglio A

更新日期：2018-12-01 00:00:00

abstract：:Evidence from epidemiologic studies suggests that periodontal infections are independently associated with subclinical and clinical atherosclerotic vascular disease. Although the strength of the reported associations is modest, the consistency of the data across diverse populations and a variety of exposure and outcom...

journal_title：Journal of dental research

authors： Kebschull M,Demmer RT,Papapanou PN

更新日期：2010-09-01 00:00:00