PPARγ Maintains Homeostasis through Autophagy Regulation in Dental Pulp.

abstract：:Amylase activity in various tissues--i.e., submandibular/sublingual and parotid glands, the pancreas, saliva, and serum--in rats was measured after injection of isoproterenol, pilocarpine, and acetylcholine. All agents reduced amylase activity in the parotid gland and increased the enzyme activity in the submandibular...

journal_title：Journal of dental research

authors： Ikeno T,Nasu J,Kuzuya H

更新日期：1983-01-01 00:00:00

abstract：:Locally applied bisphosphonates may improve the fixation of metal implants in bone. However, systemic bisphosphonate treatment is associated with a risk of osteonecrosis of the jaw (ONJ). We hypothesized that local delivery of bisphosphonate from the implant surface improves the fixation of dental implants without com...

journal_title：Journal of dental research

authors： Abtahi J,Agholme F,Sandberg O,Aspenberg P

更新日期：2013-03-01 00:00:00

abstract：:In this study, we sought to determine the association between tooth agenesis and DNA sequence variation in the genes MSX1 and PAX9 in an ethnically diverse human population. Since cleft lip/palate is also associated with both tooth agenesis and the gene TGFA, we included TGFA in the analysis as well. Cheek swab sample...

journal_title：Journal of dental research

authors： Vieira AR,Meira R,Modesto A,Murray JC

更新日期：2004-09-01 00:00:00

abstract：:The biocompatibility of two implant materials, vitallium and poly-methyl methacrylate (PMMA), was evaluated in an animal model in which bone formation and resorption are independent of each other. Neither material accelerated resorption, but formation was inhibited 12% by vitallium and 38% by PMMA. When three PMMA pre...

journal_title：Journal of dental research

authors： Garcia DA,Sullivan TM,O'Neill DM

更新日期：1981-01-01 00:00:00

abstract：:We have investigated the role of the activation of nuclear poly(ADP-ribose) polymerase (PARP) enzyme, a mediator of downstream nitric oxide toxicity, using a combined approach of pharmacological inhibition and genetic disruption in a ligature-induced-periodontitis model in rats and mice. Immunohistochemical analysis r...

journal_title：Journal of dental research

authors： Lohinai Z,Mabley JG,Fehér E,Marton A,Komjáti K,Szabó C

更新日期：2003-12-01 00:00:00

abstract：:The sagittal and frontal active envelope of border movement is applied regularly as a clinical tool in functional examinations of the human masticatory system. In contrast, the three-dimensional movement area has hardly been examined. Furthermore, the determinants of this area are not established unambiguously. In the...

journal_title：Journal of dental research

authors： Koolstra JH,Naeije M,van Eijden TM

更新日期：2001-10-01 00:00:00

abstract：:The synchronized cyrstal dissolution hypothesis previously proposed to explain the unusual dissolution behavior of human dental enamel and hydroxyapatite in partially saturated acidic media has been critically examined with dissolution-dialysis transport experiments. The findings are in accord with the hypothesis. A m...

journal_title：Journal of dental research

authors： Fawzi MB,Sonobe T,Higuchi WI,Hefferren JJ

更新日期：1977-04-01 00:00:00

abstract：:Not only are teeth essential for mastication, but also missing teeth are considered a social handicap due to speech and aesthetic problems, with a resulting high impact on emotional well-being. Several treatment procedures are currently available for tooth replacement with mostly inert prosthetic materials and implant...

journal_title：Journal of dental research

authors： Fleischmannova J,Matalova E,Sharpe PT,Misek I,Radlanski RJ

更新日期：2010-02-01 00:00:00

abstract：:The lack of a reliable bond test has hindered the elucidation of the mechanism for porcelain-metal bonding in dental systems, because a test capable of detecting differences among porcelain-metal bonds of various qualities is required before the reasons for these differences may be ascertained. A method was developed ...

journal_title：Journal of dental research

authors： Mackert JR Jr,Ringle RD,Parry EE,Evans AL,Fairhurst CW

更新日期：1988-02-01 00:00:00

abstract：:A sintered hydroxyapatite (HAP) ceramic for use in wear studies was prepared from a commercial tricalcium phosphate. The sintered HAP had physical properties close to those of human enamel. The coefficient of friction and wear of the sintered HAP ceramic as characterized by tangential force, track width, and surface f...

journal_title：Journal of dental research

authors： Rootare HM,Powers JM,Craig RG

更新日期：1978-07-01 00:00:00

abstract：:The regulation of blood flow of the dental pulp was investigated in dogs and rats anesthetized with sodium pentobarbital. Pulpal blood flow was altered by variations of local and systemic hemodynamics. Variation in pulpal hemodynamics was attained by means of close intra-arterial injections of adrenergic agonists (NE ...

journal_title：Journal of dental research

authors： Kim S

更新日期：1985-04-01 00:00:00

abstract：:Knoop hardness measurements of UV-polymerized dental composites showed that, at a certain depth below the surface, the degree of cure rapidly decreases. The depth of cure was found to be critically dependent on the UV source and exposure time used. A theoretical model was derived which was in quantitative accord with ...

journal_title：Journal of dental research

authors： Cook WD

更新日期：1980-05-01 00:00:00

abstract：:Previous studies show that both activin and Bmp4 act as crucial mesenchymal odontogenic signals during early tooth development. Remarkably, mice lacking activin-βA ( Inhba-/-) and mice with neural crest-specific inactivation of Bmp4 ( Bmp4ncko/ncko) both exhibit bud-stage developmental arrest of the mandibular molar t...

journal_title：Journal of dental research

authors： Kwon HE,Jia S,Lan Y,Liu H,Jiang R

更新日期：2017-09-01 00:00:00

abstract：:Streptococcus mutans produces 3 types of glucosyltransferase (GTF), whose cooperative action is considered to be essential for its cellular adherence to the tooth surface. However, the precise mechanisms for synthesizing adhesive glucans and the specific roles of each GTF in cellular adherence to smooth surfaces have ...

journal_title：Journal of dental research

authors： Ooshima T,Matsumura M,Hoshino T,Kawabata S,Sobue S,Fujiwara T

更新日期：2001-07-01 00:00:00

abstract：:The antimicrobial and cariostatic activities of the dihydrochloride and dihydrofluoride salts of alexidine (1,6-bis-[2-ethylhexylbiguanido]hexane) were compared to those of chlorhexidine acetate and sodium fluoride in rats implanted orally with Streptococcus mutans 6715 and fed a cariogenic diet. Experimental caries w...

journal_title：Journal of dental research

authors： Curtis SN,Dooley CL

更新日期：1979-04-01 00:00:00

abstract：:Inorganic polyphosphate [Poly(P)] is especially prevalent in osteoblasts. We tested the hypothesis that Poly(P) stimulates osteoblastic differentiation and polyphosphate metabolism for bone formation. The osteoblast-like cell line, MC 3T3-E1, was cultured with Poly(P), and gene expression was evaluated by real-time re...

journal_title：Journal of dental research

authors： Usui Y,Uematsu T,Uchihashi T,Takahashi M,Takahashi M,Ishizuka M,Doto R,Tanaka H,Komazaki Y,Osawa M,Yamada K,Yamaoka M,Furusawa K

更新日期：2010-05-01 00:00:00

abstract：:In two separate experiments, none of the 14 subunits examined consistently ranked dentifrices similarly to the ranking obtained when the individual rat was used as the experimental unit. Arbitrarily dividing the rat into subunits and then comparing results among these subunits may lead to false conclusions since the r...

journal_title：Journal of dental research

authors： Briner WW

更新日期：1976-05-01 00:00:00

abstract：:Weanling rice rats were fed either standard laboratory chow or Diet 2000. The animals were sacrificed at 4, 8, 12, and 15 weeks. There was an increasing amount of exposed root surface and root surface caries with age in the animals fed Diet 2000. There was exposed root surface but no caries in the animals fed laborato...

journal_title：Journal of dental research

authors： Doff RS,Rosen S,App G

更新日期：1977-09-01 00:00:00

abstract：:Resin-bonded bridges may replace missing teeth and act as splints in periodontal treatment. The objective of this study was to investigate the etch pattern after electrolytic etching of selected Co-Cr alloys in hydrochloric acid and to assess the changes in alloy composition after different etching times. The alloys i...

journal_title：Journal of dental research

authors： Ekstrand K,Ruyter IE

更新日期：1987-09-01 00:00:00

abstract：:During the polymerization of multifunctional monomers for dental restorations, typical final double-bond conversions range from 55 to 75%. The low conversion results in a large amount of extractable monomer, reduced adhesion to the filler, and the potential for increased swelling. In this work, the ability to increase...

journal_title：Journal of dental research

authors： Anseth KS,Goodner MD,Reil MA,Kannurpatti AR,Newman SM,Bowman CN

更新日期：1996-08-01 00:00:00

abstract：:The human patched gene (PTCH) functions in both embryologic development and tumor suppression. PTCH mutations have been found in odontogenic keratocysts. However, the expression and localization of the protein product of the gene have not been determined in odontogenic tumors and cysts. We investigated 68 odontogenic ...

journal_title：Journal of dental research

authors： Barreto DC,Bale AE,De Marco L,Gomez RS

更新日期：2002-11-01 00:00:00

abstract：:The aim of this study was to investigate the diffusion dynamics of 25% hydrogen peroxide (H2O2) through enamel-dentin layers and to correlate it with dentin's structural alterations. Micro-Raman Spectroscopy (MRS) and Fourier Transform Infrared Photoacoustic Spectroscopy (FTIR-PAS) were used to measure the spectra of ...

journal_title：Journal of dental research

authors： Ubaldini AL,Baesso ML,Medina Neto A,Sato F,Bento AC,Pascotto RC

更新日期：2013-07-01 00:00:00

abstract：:The periodontal ligament (PDL) works as a suspensory ligament when external mechanical stress is placed on the teeth. PDL fibroblasts, the principal cells in the PDL, are responsible for many PDL functions. We hypothesized that mechanosensitive ion channels are present in human PDL fibroblasts, which are capable of re...

journal_title：Journal of dental research

authors： Ohara A,Saeki Y,Nishikawa M,Yamamoto Y,Yamamoto G

更新日期：2006-07-01 00:00:00

abstract：:Mandibular prognathism is a common dentofacial phenotype with a substantial genetic component; however, few susceptibility loci have been mapped. Ethnicity is a risk factor for mandibular prognathism, and a relatively high prevalence is observed in Asian populations. The hypothesis of this study suggested that a speci...

journal_title：Journal of dental research

authors： Li Q,Li X,Zhang F,Chen F

更新日期：2011-01-01 00:00:00

abstract：:Blood cortisol levels of oral surgery patients were analyzed to objectively determine the effect of intravenous sedation on surgical stress. Results showed a measure of sedation but did not adequately reflect the stress of oral surgery or the changes produced by intravenous sedation. ...

journal_title：Journal of dental research

authors： Bunch FL,Allen GD,Jorgensen NB

更新日期：1975-09-01 00:00:00

abstract：:Physico-chemical investigations of enamel from deciduous teeth of a small number of children with and without pre-natal fluoride supplementation (PNF) exhibited the following differences between the PNF and non-PNF enamel, with the former showing: (a) more homogeneous and less extensive patterns of acid-etching; (b) d...

journal_title：Journal of dental research

authors： LeGeros RZ,Glenn FB,Lee DD,Glenn WD

更新日期：1985-03-01 00:00:00

abstract：:Periodontitis is characterized by periodontal tissue destruction. Since interleukin-17 (IL-17) has been reported to up-regulate IL-1beta and tumor necrosis factor-alpha (TNF-alpha), it was hypothesized that it is increased in periodontitis and up-regulates these cytokines and tissue-destructive matrix metalloproteinas...

journal_title：Journal of dental research

authors： Beklen A,Ainola M,Hukkanen M,Gürgan C,Sorsa T,Konttinen YT

更新日期：2007-04-01 00:00:00

abstract：:In order for the role of parotid amylase in starch digestion in the gastro-intestinal tracts of diabetic rats to be clarified, this study investigated the effect of parotid-duct ligation on both amylase secretion from the parotid glands and pancreas into the gastro-intestinal tract and on starch digestion in the gastr...

journal_title：Journal of dental research

authors： Kurahashi M,Inomata K

更新日期：1989-09-01 00:00:00

abstract：:Numerous studies have demonstrated that many older adults have problems chewing, pain, difficulties in eating, and problems in social relationships because of oral disorders. However, it is not clear if these functional and psychosocial outcomes affect broader psychological well-being and life satisfaction. Consequent...

journal_title：Journal of dental research

authors： Locker D,Clarke M,Payne B

更新日期：2000-04-01 00:00:00

abstract：:While dental pulp appears to be able to form mineralized matrices that do not always resemble dentin, the precise characteristics of the hard tissue and the mechanism of its induction remain unknown. Therefore, we evaluated hard tissue induced by transplantation of pulp into subcutaneous tissue. Seven days after trans...

journal_title：Journal of dental research

authors： Hosoya A,Nakamura H,Ninomiya T,Hoshi K,Yoshiba K,Yoshiba N,Takahashi M,Okabe T,Sahara N,Yamada H,Kasahara E,Ozawa H

更新日期：2007-05-01 00:00:00