Abstract:
:The synchronized cyrstal dissolution hypothesis previously proposed to explain the unusual dissolution behavior of human dental enamel and hydroxyapatite in partially saturated acidic media has been critically examined with dissolution-dialysis transport experiments. The findings are in accord with the hypothesis. A model based upon a variable effective solubility for the hydroxyapatite crystal is proposed.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Fawzi MB,Sonobe T,Higuchi WI,Hefferren JJdoi
10.1177/00220345770560040701subject
Has Abstractpub_date
1977-04-01 00:00:00pages
394-406issue
4eissn
0022-0345issn
1544-0591journal_volume
56pub_type
杂志文章abstract::Since the exposure of mutans streptococci to xylitol is known to select for xylitol-resistant (XR) natural mutants, the occurrence and long-term survival of such xylitol-resistant strains was evaluated in a cross-sectional sampling of participants of the Ylivieska xylitol study four years after the original two-year e...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345920710110401
更新日期:1992-11-01 00:00:00
abstract::Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects, HPP causes dental...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515573273
更新日期:2015-05-01 00:00:00
abstract::The spatial relationship of the mandibular condyle to the temporal component of the TMJ is determined quantitatively from lateral tomograms using a new method of measuring specific areas of the joint space. Condyle position along the posteroanterior axis of the joint is expressed as a ratio of the posterior joint spac...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600010701
更新日期:1981-01-01 00:00:00
abstract::Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516645796
更新日期:2016-08-01 00:00:00
abstract::The range of substrates transported by the sugar-binding protein-dependent msm (multiple sugar metabolism) system of S. mutans was investigated. By determining the ability of unlabeled sugar to compete with radiolabeled melibiose transport, we have demonstrated that the transported sugars included a number of carbohyd...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720100701
更新日期:1993-10-01 00:00:00
abstract::This 24-mo randomized controlled trial was based on a double-blind parallel design, and it compared the effectiveness of 2 fluoride application protocols in arresting dentine caries in primary teeth. Three-year-old children with active dentine caries were recruited and randomly allocated to 2 treatment groups. Childre...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520952031
更新日期:2021-01-01 00:00:00
abstract::The limited durability of resin-dentin bonds severely compromises the lifetime of tooth-colored restorations. Bond degradation occurs via hydrolysis of suboptimally polymerized hydrophilic resin components and degradation of water-rich, resin-sparse collagen matrices by matrix metalloproteinases (MMPs) and cysteine ca...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034510391799
更新日期:2011-08-01 00:00:00
abstract::Stable fluoride-resistant mutants of Streptococcus mutans GS-5 were isolated on Todd-Hewitt agar by a step-wise selection procedure. Resistance is defined here as the ability to form colonies in 48 hr. First-step mutants demonstrated six different levels of resistance, ranging from 400 to 1000 micrograms/mL sodium flu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660101701
更新日期:1987-10-01 00:00:00
abstract::Rotational freedom of the implant-abutment connection influences its screw joint stability; for optimization, influential factors need to be evaluated based on a previously developed closed formula. The underlying hypothesis is that the manufacturing tolerances, geometric pattern, and dimensions of the index do not in...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509341243
更新日期:2009-08-01 00:00:00
abstract::Obesity is a widespread chronic inflammatory disorder characterized by an increased overall disease burden and significant association with periodontitis. The aim of this prospective clinical cohort study was to investigate the effect of obesity on orthodontic tooth movement. Fifty-five adolescent patients (27 males, ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516688448
更新日期:2017-05-01 00:00:00
abstract::The aim of this study was to assess the changes occurring in subgingival biofilm composition and in the periodontal clinical parameters of subjects with periodontitis and type 2 diabetes mellitus (DM) treated by means of scaling and root planing (SRP) only or combined with systemic metronidazole (MTZ) and amoxicillin ...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/0022034516639274
更新日期:2016-07-01 00:00:00
abstract::Sjögren's syndrome is a common autoimmune rheumatic disease. The most common symptoms of Sjögren's syndrome are extreme tiredness, along with dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia). Saliva plays an essential role in numerous functions of the mouth. Xerostomia can be caused by medications, chr...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/154405910808700411
更新日期:2008-04-01 00:00:00
abstract::Periodontal disease is a bacterial infection that results in inflammatory destruction of tissues that support the teeth, including connective tissue and bone. In this study, we report that transgenic mice that overexpress the 17-kDa form of IL-1alpha in the basal layer of oral mucosal epithelium develop a syndrome tha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408301010
更新日期:2004-10-01 00:00:00
abstract::Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034517726284
更新日期:2017-10-01 00:00:00
abstract::Previous studies have demonstrated that antibodies against cholinoreceptors of exocrine glands correlate with dry mouth in persons with primary Sjögren syndrome (pSS). The aim of the present investigation was to establish if serum IgG antibodies (pSS IgG) were able to interact with cholinoreceptors in rat submandibula...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600905
更新日期:2007-09-01 00:00:00
abstract::Epstein-Barr virus (EBV), in addition to its transforming properties, contributes to the pathogenesis of several inflammatory diseases. Here, we investigated its involvement in oral lichen planus (OLP), a common autoimmune-like disease of unknown etiopathogenesis that can display a malignant potential. EBV-infected ce...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034518788282
更新日期:2018-12-01 00:00:00
abstract::The acquired enamel pellicle is an oral, fluid-derived protein layer that forms on the tooth surface. It is a biologically and clinically important integument that protects teeth against enamel demineralization, and abrasion. Tooth surfaces are exposed to different proteinaceous microenvironments depending on the enam...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516680771
更新日期:2017-04-01 00:00:00
abstract::The histopathologic status of gingival tissue was assessed according to the criteria of Page and Schroeder.(5) Rhodamine-labeled bacteria were used to assess the antigenic specificity of plasma cells in the tissue. Examination of tissue sections revealed that 31.6% of plasma cells in the advanced lesions bound the lab...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034580059S213
更新日期:1980-11-01 00:00:00
abstract::The clearance of glucose from saliva was compared with that from spaces located in an intra-oral appliance. The spaces (N = 8) were similar in shape and size to posterior interdental spaces and could be sampled with a microsyringe without removing the appliance from the mouth. The subjects (N = 5) rinsed their mouths ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345850640030301
更新日期:1985-03-01 00:00:00
abstract::Because bone reconstruction in irradiated sites is less than ideal, we applied a regenerative gene therapy method in which a cell-signaling virus was localized to biomaterial scaffolds to regenerate wounds compromised by radiation therapy. Critical-sized defects were created in rat calvariae previously treated with ra...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509352151
更新日期:2010-01-01 00:00:00
abstract::The eventual outcome of dental caries is determined by the dynamic balance between pathological factors that lead to demineralization and protective factors that lead to remineralization. Pathological factors include acidogenic bacteria, inhibition of salivary function, and frequency of ingestion of fermentable carboh...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/154405910408301s08
更新日期:2004-01-01 00:00:00
abstract::Extracellular matrix (ECM) mineralization is regulated by mineral ion availability, proteins, and other molecular determinants. To investigate protein regulation of mineralization in tooth dentin and cementum, and in alveolar bone, we expressed matrix Gla protein (MGP) ectopically in bones and teeth in mice, using an ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700907
更新日期:2008-09-01 00:00:00
abstract::Adhesion of restorative and protective materials to dentin is an important requirement for operative and preventive dentistry. Wettability and roughness are dentin substrate conditions that are critical to establishing good adhesion. This study examined superficial and deep dentin for variations in water contact angle...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345990780091001
更新日期:1999-09-01 00:00:00
abstract::The human dentition is a complex adaptive system that is influenced by genetic, epigenetic, and environmental factors. Within this system, is sexual dimorphism related to the growth promotion of the Y chromosome, or to hormonal influences, or both? This study is the first to investigate both primary and permanent toot...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513484934
更新日期:2013-05-01 00:00:00
abstract::With clinical oral examinations not always possible in health surveys, researchers may instead be invited to add questions to a wider health survey. In such situations, an item is needed which adequately represents both clinical and self-reported oral health. This study investigated the clinical validity of Locker's g...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512460676
更新日期:2012-11-01 00:00:00
abstract::Recent evidence implicates endothelin in nociception, but it is unclear how endothelin activates trigeminal ganglion (TRG) neurons. In the present study, we investigated the expression of the endothelin receptors ETA and ETB and endothelin-induced responses in rat TRG neurons. Double-immunofluorescence studies demonst...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513478428
更新日期:2013-04-01 00:00:00
abstract::Masticatory muscle silent periods were compared in normal subjects and in patients with MPD syndrome before and after a variety of psychological, physiological, and pharmacological forms of therapy. All patients initially showed prolonged silent periods in one or more of the muscles. There was a direct relationship be...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600030501
更新日期:1981-03-01 00:00:00
abstract::The aim of this study was to test the hypothesis that the chewing of xylitol- or xylitol/sorbitol-containing chewing gum reduces plaque formation and the acidogenic potential of dental plaque. Thirty healthy volunteers aged from 19 to 28 yrs were randomly allocated to one of three test groups, chewing either xylitol-,...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/00220345980770071001
更新日期:1998-07-01 00:00:00
abstract::The reaction of the microvasculature in the periodontal ligament to mechanical pressure is considered a very important phenomenon with respect to the biological background to orthodontic tooth movement. For clarification of the microvascular reaction to mechanical pressure, an experimental model that incorporated a ha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345920710060701
更新日期:1992-06-01 00:00:00
abstract::In the past two decades, accumulated evidence has clearly demonstrated the inhibitory effects of laser irradiation on enamel demineralization, but the exact mechanisms of these effects remain unclear. The purpose of this study was to investigate the effects of low-energy CO2 laser irradiation on demineralization of bo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790091401
更新日期:2000-09-01 00:00:00