Abstract:
:A new hydroxyapatite ceramic implant material for restoration of atrophic edentulous ridges was tested in a canine animal model. The structure of this material is unique, in that it is produced from the skeleton of a coral, and in that it is penetrated by a uniform network of interconnected pores. Results indicate that bone penetrates its structure to a greater degree than had been observed with similar implants constructed of different materials. Implant insertion through a simple surgical technique involving minimal morbidity is a viable method of placement.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Piecuch JF,Topazian RG,Skoly S,Wolfe Sdoi
10.1177/00220345830620021301subject
Has Abstractpub_date
1983-02-01 00:00:00pages
148-54issue
2eissn
0022-0345issn
1544-0591journal_volume
62pub_type
杂志文章abstract::Antigenic alterations to the dentin organic matrix may be detected by an immunohistochemical approach. We hypothesized that alterations in the antigenicity of type I collagen and proteoglycans occur in sclerotic dentin under caries lesions. Transverse sections were prepared from carious teeth in the sclerotic zone and...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910608500204
更新日期:2006-02-01 00:00:00
abstract::In 1984, a four-year mixed-longitudinal study of oral health was begun in Morogoro Town and Morogoro District, Tanzania. Its main goal was to detect a possible upward trend in prevalence of caries in child cohorts in this developing country. The sample consisted of 722 seven- to nine-year-olds in 1984, 833 seven- to 1...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680121101
更新日期:1989-12-01 00:00:00
abstract::T6 antigen is a highly specific marker for human Langerhans cells (LC). Previous studies have demonstrated that Interleukin-1 (IL-1) and an IL-1 inhibitor (ILS) modulate LC T6 expression (T6E) in explant culture. The present study examined the in vitro modulation of T6E by two molecules: epidermal-cell-derived thymocy...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660031201
更新日期:1987-03-01 00:00:00
abstract::Odontoblasts and fibroblasts are suspected to influence the innate immune response triggered in the dental pulp by micro-organisms that progressively invade the human tooth during the caries process. To determine whether they differ in their responses to oral pathogens, we performed a systematic comparative analysis o...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700304
更新日期:2008-03-01 00:00:00
abstract::Short-chain carboxylic acids (e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which can accumulate in the gingival crevice. It is of no small consequence, therefore, that 1- to 5-mM concentrations of these acids exhibit significant biological activity, including the a...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760010801
更新日期:1997-01-01 00:00:00
abstract::The incisor dentin of hypophosphatemic (Hyp) mice was examined histopathologically to determine whether the multiple occurrences of interglobular dentin would be influenced by the serum phosphate level. Both normal and Hyp mice (12 weeks of age) were divided into two groups. The mice in one group were given a control ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345920710031101
更新日期:1992-03-01 00:00:00
abstract::Direct FA staining for S mutans serotypes may be performed on smears made from plaque or strain isolates and on colonies attached to agar plates of black membrane filters. Staining with single conjugates directed to S mutans serotypes (a to e) as well as with polyvalent a-, b-, d-, f-fluorescein label and c-, e-rhodam...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/002203457605500126011
更新日期:1976-01-01 00:00:00
abstract::Morphogenesis (germ-tube formation) in Candida albicans was induced gratuitously by N-acetylhexosamine derivatives (N-acetyl-glucosamine covalently linked to agarose, N-acetylmannosamine, hyaluronic acid, colloidal chitin, and mucin). These compounds were not taken up by the yeast cells and did not support growth. 2-D...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345840630031501
更新日期:1984-03-01 00:00:00
abstract::Four classes of elastomeric impression materials (polysulfide, polyether, silicone, and agar-agar) were evaluated on the basis of linear dimensional stability as a function of time between taking and pouring an impression of mounted teeth. Four polysulfide materials produced dies which were larger than the teeth and g...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590071001
更新日期:1980-07-01 00:00:00
abstract::We analyzed the flow rate and composition of paraffin-stimulated whole saliva samples from 35 adult diabetic patients and their age- and sex-matched, non-diabetic, clinically healthy controls. All patients had insulin-dependent diabetes (IDDM) with a mean (+/- S.D.) duration of 14.0 +/- 9.1 years. The saliva analysis ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650011101
更新日期:1986-01-01 00:00:00
abstract::Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511429346
更新日期:2012-02-01 00:00:00
abstract::Enamel fluorosis can occur following either an acute or chronic exposure to fluoride during tooth formation. Fluorosed enamel is characterized by a retention of amelogenins in the early-maturation stage, and by the formation of a more porous enamel with a subsurface hypomineralization. The mechanisms by which fluoride...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345920710051701
更新日期:1992-05-01 00:00:00
abstract::Stress-induced changes imparted in a 'dentin-bonded-crown' material during sintering, annealing, pre-cementation surface modification, and resin coating have been visualized by profilometry. The hypothesis tested was that operative techniques modify the stressing pattern throughout the material thickness. We polished ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509354049
更新日期:2010-01-01 00:00:00
abstract::Periodontitis is characterized by periodontal tissue destruction. Since interleukin-17 (IL-17) has been reported to up-regulate IL-1beta and tumor necrosis factor-alpha (TNF-alpha), it was hypothesized that it is increased in periodontitis and up-regulates these cytokines and tissue-destructive matrix metalloproteinas...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600409
更新日期:2007-04-01 00:00:00
abstract::Eighteen different Streptococcus strains including S mutans, sanguis, mitis, salivarius, bovis, and 2F2, were assayed for their relative adsorption to synthetic hydroxyapatite and for quantities of lactic acid produced while in the adsorbed state. The results indicated that all S mutans and some S sanguis have an enha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560101401
更新日期:1977-10-01 00:00:00
abstract::Gingival overgrowth is a common side-effect of the administration of cyclosporin A (CSA), phenytoin, and calcium blockers. To identify the signaling mechanisms possibly involved in the overgrowth, we examined how CSA affects the activities of MAP kinases and transcription factors in human gingival fibroblasts (HGF). T...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910508400609
更新日期:2005-06-01 00:00:00
abstract::Components of resin materials may damage DNA, leading to genetic alterations in mammalian cells. Here, monomers were analyzed for the induction of chromosomal aberrations indicated by micronuclei induced in V79 cells. A dose-related increase in the numbers of micronuclei was observed with triethyleneglycol dimethacryl...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345010800070401
更新日期:2001-07-01 00:00:00
abstract::The objectives of this study were 1) to provide an estimate of the value of the intraclass correlation coefficient (ICC) for dental caries data at tooth and surface level, 2) to provide an estimate of the design effect (DE) to be used in the determination of sample size estimates for future dental surveys, and 3) to e...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514559408
更新日期:2015-02-01 00:00:00
abstract::A gravity sintering fabrication technique has been developed for producing Co-Cr-Mo alloy dental implants having a porous coating on the root portion. This process allows for control of pore structure enabling ingrowth of either bone or fibrous tissue. The microstructure and mechanical properties of these materials ha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560050501
更新日期:1977-05-01 00:00:00
abstract::The effects of different doses of p-tyramine injected i.v. and i.p. on salivary flow rates and proteins secreted by the submandibular glands of rats were studied with and without various types of autonomic blockers and two enzyme inhibitors. The salivary flow rates and the amounts of protein secreted progressively inc...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720051101
更新日期:1993-05-01 00:00:00
abstract::Potentially significant associations between periodontal disease and chronic kidney disease (CKD) have been reported in recent studies. The aim of this cross-sectional study was to investigate the association between serum antibody to the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) and CKD in 215 Jap...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512455063
更新日期:2012-09-01 00:00:00
abstract::The study of biofilm structure and function mandates the use of model systems for which a host of environmental variables can be rigorously controlled. We describe a model of supragingival plaque containing Actinomyces naeslundii, Veillonella dispar, Fusobacterium nucleatum, Streptococcus sobrinus, and Streptococcus o...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345010800011201
更新日期:2001-01-01 00:00:00
abstract::In sham-operated and TPTX animals, F treatment did not affect final body weight, or serum Ca and P. In sham-treated rats, serum iPTH was not affected by F treatment. At the periosteum, F increased bone formation rate and bone and matrix apposition rates. At the endosteum, F treatment decreased forming surface, bone fo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560031601
更新日期:1977-03-01 00:00:00
abstract::Biological mediators have been used to enhance periodontal regeneration. The aim of this prospective randomized controlled study was to evaluate the safety and effectiveness of 3 doses of fibroblast growth factor 2 (FGF-2) when combined with a β-tricalcium phosphate (β-TCP) scaffold carrier placed in vertical infrabon...
journal_title:Journal of dental research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/0022034516632497
更新日期:2016-05-01 00:00:00
abstract::The goal of nonrestorative or non- and microinvasive caries treatment (fluoride- and nonfluoride-based interventions) is to manage the caries disease process at a lesion level and minimize the loss of sound tooth structure. The purpose of this systematic review and network meta-analysis was to summarize the available ...
journal_title:Journal of dental research
pub_type: 杂志文章,meta分析
doi:10.1177/0022034518800014
更新日期:2019-01-01 00:00:00
abstract::The acquired dental pellicle helps prevent erosion, but the protection level is unknown. This in situ study tested whether a two-hour pellicle protects against different erosive challenges by orange juice. Subjects wore palatal appliances loaded with either enamel or dentin specimens. Pellicle was allowed to form, or ...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/154405910608500706
更新日期:2006-07-01 00:00:00
abstract::This study has identified and characterized class II (Ia) antigen-expressing cells in the normal rat incisor pulp by immunohistochemistry and flow cytometry. Two types of Ia-expressing cells occurred: one with a pronounced dendritic appearance located primarily in the periphery of the pulp, and one with morphological ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670100301
更新日期:1988-10-01 00:00:00
abstract::The authors tested the hypothesis that obstructive sleep apnea (OSA) signs/symptoms are associated with the occurrence of temporomandibular disorder (TMD), using the OPPERA prospective cohort study of adults aged 18 to 44 years at enrollment (n = 2,604) and the OPPERA case-control study of chronic TMD (n = 1,716). In ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513488140
更新日期:2013-07-01 00:00:00
abstract::Chronic periodontitis is a multi-factorial disease involving anaerobic bacteria and the generation of an inflammatory response, including the production of metalloproteinases, pro-inflammatory cytokines, and eicosanoids. Hypochlorous acid (HOCl) and taurine-N-monochloramine (TauCl) are the end-products of the neutroph...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/154405910408301101
更新日期:2004-11-01 00:00:00
abstract::Caries increment is affected by sugar-sweetened beverage (SSB) consumption. Taxing SSBs could reduce sugar consumption and caries increment. The authors aimed to estimate the impact of a 20% SSB sales tax on caries increment and associated treatment costs (as well as the resulting tax revenue) in the context of German...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516660278
更新日期:2016-11-01 00:00:00