Stimulation of bone formation and bone resorption by fluoride in thyroparathyroidectomized rats.

abstract：:The inhibitory activity of 2-phosphono-butane 1,2,4 tricarboxylic acid (PBTA) in the formation of hydroxyapatite (HA) was studied in vitro and in vivo. PBTA, at 4 ppm, inhibited the spontaneous formation of HA in vitro from a supersaturated solution. PBTA, at 2 ppm, completely inhibited the crystal growth of HA; at lo...

journal_title：Journal of dental research

authors： Gaffar A,Moreno EC

更新日期：1985-01-01 00:00:00

abstract：:The objective of this study was to assess the relative effects of age and oral hygiene on the progression of periodontitis by estimating incidence from age-specific prevalence. This study analyzed data from a representative national sample of 14,690 dentate Americans, aged from 15 to 74, seen in the first National Hea...

journal_title：Journal of dental research

authors： Abdellatif HM,Burt BA

更新日期：1987-01-01 00:00:00

abstract：:Juvenile rheumatoid arthritis (JRA) is a chronic systemic disease of childhood that affects synovial joints including the temporomandibular joint (TMJ). Individuals with JRA of the TMJ frequently show aberrations in mandibulofacial development. Since the basis for these developmental perturbations is poorly understood...

journal_title：Journal of dental research

authors： Tavakkoli-Jou M,Miller AJ,Kapila S

更新日期：1999-08-01 00:00:00

abstract：:Previous studies have clearly established the down-regulating effect of a sucrose-rich diet on primary dentinogenesis in rat molars. Earlier observation of the negative effect of a high-sucrose diet on a parotid function involved in the control of intradentinal solute movement led us to hypothesize that parotid gland ...

journal_title：Journal of dental research

authors： Leonora J,Tjäderhane L,Tieche JM

更新日期：2002-04-01 00:00:00

abstract：:Dimensions and velocity of mandibular movement are important variables in the evaluation of masticatory and speech patterns. However, little information is available concerning elderly dentates and their oral motor function and behavior. Double recordings of a chewing period, from start to swallowing, were performed i...

journal_title：Journal of dental research

authors： Karlsson S,Carlsson GE

更新日期：1990-02-01 00:00:00

abstract：:The spatial relationship of the mandibular condyle to the temporal component of the TMJ is determined quantitatively from lateral tomograms using a new method of measuring specific areas of the joint space. Condyle position along the posteroanterior axis of the joint is expressed as a ratio of the posterior joint spac...

journal_title：Journal of dental research

authors： Blaschke DD,Blaschke TJ

更新日期：1981-01-01 00:00:00

abstract：:Heterozygous mutations in the RUNX2 (CBFA1) gene cause cleidocranial dysplasia, characterized by multiple supernumerary teeth. This suggests that Runx2 inhibits successional tooth formation. However, in Runx2 knockout mice, molar development arrests at the late bud stage, and lower molars are more severely affected th...

journal_title：Journal of dental research

authors： Wang XP,Aberg T,James MJ,Levanon D,Groner Y,Thesleff I

更新日期：2005-02-01 00:00:00

abstract：:Fungal infections in the oral cavity are mainly caused by C. albicans, but other Candida species are also frequently identified. They are increasing in prevalence, especially in denture-wearers and aging people, and may lead to invasive infections, which have a high mortality rate. Attachment to mucosal tissues and to...

journal_title：Journal of dental research

authors： ten Cate JM,Klis FM,Pereira-Cenci T,Crielaard W,de Groot PW

更新日期：2009-02-01 00:00:00

abstract：:The tissue-implant interfaces of functional and non-functional endosseous dental implants were compared histologically for up to one year post-operatively. Nonmineralized connective tissue zones (a "fibrous capsule") existed in all functional interfaces. Direct, or nearly direct, bone apposition to implants occurred i...

journal_title：Journal of dental research

authors： Brunski JB,Moccia AF Jr,Pollack SR,Korostoff E,Trachtenberg DI

更新日期：1979-10-01 00:00:00

abstract：:An analysis of the relationship between creep and microstructural characteristics of several gamma2-containing amalgams showed the grain size of the Ag-Hg phase (gamma1) to be a predominant factor influencing creep. When gamma1 grain size is increased, creep is reduced. ...

journal_title：Journal of dental research

authors： Mahler DB,Adey JD,Marantz RL

更新日期：1977-12-01 00:00:00

abstract：:The tongue exerts crucial functions in our daily life. However, we know very little about the regulatory mechanisms of mammalian tongue development. In this review, we summarize recent findings of the molecular and cellular mechanisms that control tissue-tissue interactions during tongue morphogenesis. Specifically, c...

journal_title：Journal of dental research

authors： Parada C,Han D,Chai Y

更新日期：2012-06-01 00:00:00

abstract：:In this study, we sought to determine the association between tooth agenesis and DNA sequence variation in the genes MSX1 and PAX9 in an ethnically diverse human population. Since cleft lip/palate is also associated with both tooth agenesis and the gene TGFA, we included TGFA in the analysis as well. Cheek swab sample...

journal_title：Journal of dental research

authors： Vieira AR,Meira R,Modesto A,Murray JC

更新日期：2004-09-01 00:00:00

abstract：:The acquired enamel pellicle is an oral, fluid-derived protein layer that forms on the tooth surface. It is a biologically and clinically important integument that protects teeth against enamel demineralization, and abrasion. Tooth surfaces are exposed to different proteinaceous microenvironments depending on the enam...

journal_title：Journal of dental research

authors： Heller D,Helmerhorst EJ,Oppenheim FG

更新日期：2017-04-01 00:00:00

abstract：:Numerous studies have demonstrated that many older adults have problems chewing, pain, difficulties in eating, and problems in social relationships because of oral disorders. However, it is not clear if these functional and psychosocial outcomes affect broader psychological well-being and life satisfaction. Consequent...

journal_title：Journal of dental research

authors： Locker D,Clarke M,Payne B

更新日期：2000-04-01 00:00:00

abstract：:Treatment of bisphosphonate-related osteonecrosis of the jaw (BRONJ) has posed significant challenges to maxillofacial surgeons because of the poor repair of BRONJ bone defects. Moreover, the pathological mechanisms remain unclear. Bone marrow stromal cells (BMSCs) play key roles during bone repair and bone regenerati...

journal_title：Journal of dental research

authors： He LH,Xiao E,An JG,He Y,Chen S,Zhao L,Zhang T,Zhang Y

更新日期：2017-05-01 00:00:00

abstract：:In this study, we investigated whether selective activation of nociceptive primary afferent fibers by capsaicin would induce modulations on tooth-pulp-evoked sensory or inhibitory masseter reflex responses in healthy human subjects. The contribution of central N-methyl-D-aspartate (NMDA) receptor mechanisms in capsaic...

journal_title：Journal of dental research

authors： Kemppainen P,Waltimo A,Waltimo T,Könönen M,Pertovaara A

更新日期：1997-09-01 00:00:00

abstract：UNLABELLED:The aim of this cross-over, randomized, single-blinded trial was to examine whether intra-esophageal acidification induces sleep bruxism (SB). Polysomnography with electromyogram (EMG) of masseter muscle, audio-video recording, and esophageal pH monitoring were performed in a sleep laboratory. Twelve healthy...

journal_title：Journal of dental research

authors： Ohmure H,Oikawa K,Kanematsu K,Saito Y,Yamamoto T,Nagahama H,Tsubouchi H,Miyawaki S

更新日期：2011-05-01 00:00:00

abstract：:Current knowledge regarding the sensitivity of the teeth to forces is based on psychophysical experiments that measured touch detection thresholds under static jaw conditions. It is not known whether jaw movements alter the perception of forces applied to the teeth, but, based on limb movement studies, it is hypothesi...

journal_title：Journal of dental research

authors： Sowman PF,Brinkworth RS,Türker KS

更新日期：2010-04-01 00:00:00

abstract：:Six subjects wore intra-oral devices carrying eight bovine enamel blocks which were covered with a layer of S. mutans. They rinsed their mouths for five sec, one min, or multiples of one min with a 5 or 10% glucose (G) solution. Demineralization was measured after 45 min by determining the change in iodide permeabilit...

journal_title：Journal of dental research

authors： Tehrani A,Goulet D,Brudevold F,Attarzadeh F

更新日期：1986-02-01 00:00:00

abstract：:Genetic approaches are rapidly yielding new information about our sense of taste. This information comes from both molecular studies of genes encoding taste receptors and other taste-signaling components, and from studies of inherited variation in taste abilities. Our understanding of bitter taste has advanced by comb...

journal_title：Journal of dental research

authors： Kim UK,Breslin PA,Reed D,Drayna D

更新日期：2004-06-01 00:00:00

abstract：:Chemotherapeutics are presently considered for use in caries-preventive programs. The laboratory and in vivo testing of these agents, to some extent, parallels the methodology developed for the evaluation of fluoride products. However, fluoride is primarily effective by interfering with the de- and remineralization ba...

journal_title：Journal of dental research

authors： ten Cate JM,Marsh PD

更新日期：1994-03-01 00:00:00

abstract：:Locally applied bisphosphonates may improve the fixation of metal implants in bone. However, systemic bisphosphonate treatment is associated with a risk of osteonecrosis of the jaw (ONJ). We hypothesized that local delivery of bisphosphonate from the implant surface improves the fixation of dental implants without com...

journal_title：Journal of dental research

authors： Abtahi J,Agholme F,Sandberg O,Aspenberg P

更新日期：2013-03-01 00:00:00

abstract：:Periodontal ligament (PDL) cells play an important role in maintaining the homeostasis of periodontal tissues. However, it is not known how PDL cells contribute to osteoclastogenesis. In this study, we examined the consequences of cell-to-cell interactions between peripheral blood mononuclear cells (PBMCs) and PDL cel...

journal_title：Journal of dental research

authors： Kanzaki H,Chiba M,Shimizu Y,Mitani H

更新日期：2001-03-01 00:00:00

abstract：:The ability of adhesive resins to restore the physical properties of demineralized dentin has not been well-documented. The unfilled resins that are used for adhesion have relatively low moduli of elasticity and limited ability to increase dentin stiffness, although they may increase the ultimate tensile strength of d...

journal_title：Journal of dental research

authors： Sano H,Takatsu T,Ciucchi B,Russell CM,Pashley DH

更新日期：1995-04-01 00:00:00

abstract：:Although dental amalgam is used frequently under artificial crowns for restoration of severely damaged teeth, there is little information available on the bond between luting cements and this alloy. This study was designed for determination of the strength of the bond between a dental amalgam alloy and three crown-lut...

journal_title：Journal of dental research

authors： Mojon P,Hawbolt EB,MacEntee MI,Belser UC

更新日期：1989-11-01 00:00:00

abstract：:The antimicrobial and cariostatic activities of the dihydrochloride and dihydrofluoride salts of alexidine (1,6-bis-[2-ethylhexylbiguanido]hexane) were compared to those of chlorhexidine acetate and sodium fluoride in rats implanted orally with Streptococcus mutans 6715 and fed a cariogenic diet. Experimental caries w...

journal_title：Journal of dental research

authors： Curtis SN,Dooley CL

更新日期：1979-04-01 00:00:00

abstract：:Previous studies have shown that extracts of various filling materials, e.g., resin composites, may influence the growth of cariogenic micro-organisms. The purpose of this study was to examine the effects of important resin composite (co)monomers (Bis-GMA, UDMA, TEGDMA, EGDMA) and extracts of two commercial dental com...

journal_title：Journal of dental research

authors： Hansel C,Leyhausen G,Mai UE,Geurtsen W

更新日期：1998-01-01 00:00:00

abstract：:Macrophage colony-stimulating factor (CSF-1) is a key regulatory cytokine for amelogenesis, and ameloblasts synthesize CSF-1. We hypothesized that PDGF stimulates DNA synthesis and regulates CSF-1 in these cells. We determined the effect of PDGF on CSF-1 expression using MEOE-3M ameloblasts as a model. By RT-PCR, MEOE...

journal_title：Journal of dental research

authors： Wittrant Y,Bhandari BS,Abboud H,Benson N,Woodruff K,MacDougall M,Abboud-Werner S

更新日期：2008-01-01 00:00:00

abstract：:Proteolytic hydrolysis of casein and porcine or bovine glycoproteins by S mutans was demonstrated in the present study. Caseinolytic activity was found in both the soluble contents of the cells and the cellular debris after rupture of the cells. However, caseinolytic activity could not be demonstrated after growth in ...

journal_title：Journal of dental research

authors： Cowman RA,Perrella MM,Fitzgerald RJ

更新日期：1976-05-01 00:00:00

abstract：:Although osteoporosis is a major public health concern, the effect of this condition on oral bone has not been determined. Using the ovariectomized rat as a model, we examined whether acute estrogen depletion affects the mandible of the ovariectomized rat with and without maxillary molar extraction. Twenty-two ovariec...

journal_title：Journal of dental research

authors： Elovic RP,Hipp JA,Hayes WC

更新日期：1994-11-01 00:00:00