Abstract：
:Previous studies have shown that extracts of various filling materials, e.g., resin composites, may influence the growth of cariogenic micro-organisms. The purpose of this study was to examine the effects of important resin composite (co)monomers (Bis-GMA, UDMA, TEGDMA, EGDMA) and extracts of two commercial dental composites with similar composition (composite A, Arabesk; composite S, Superlux) on the growth of the two cariogenic bacterial pathogens Streptococcus sobrinus and Lactobacillus acidophilus. It was found that neither the monomers Bis-GMA and UDMA, nor the comonomer EGDMA, nor the extract of composite A influenced the growth of S. sobrinus in the log phase. The comonomer TEGDMA and the extract of composite S were found to stimulate growth in the log phase, but this stimulation was not statistically significant. However, EGDMA, TEGDMA, and the extract of composite S did stimulate the total growth of S. sobrinus. In the assays with L. acidophilus, Bis-GMA, UDMA, and the extract of composite A inhibited the growth in the log phase, whereas TEGDMA stimulated it. Furthermore, EGDMA, TEGDMA, and the extract of composite S stimulated the biomass production of L. acidophilus. We conclude from our results that a release of EGDMA and TEGDMA from resin composites should be avoided due to their growth-stimulating effects on the caries-associated micro-organisms S. sobrinus and L. acidophilus.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Hansel C,Leyhausen G,Mai UE,Geurtsen Wdoi
10.1177/00220345980770010601subject
Has Abstractpub_date
1998-01-01 00:00:00pages
60-7issue
1eissn
0022-0345issn
1544-0591journal_volume
77pub_type
杂志文章abstract：:Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct mechanisms. Here we review recent advances in our understanding of inflammatory tooth pain and discuss 3 hypotheses proposed to explain dentinal hypersensitivity: The first hypothesis, supported by functional expression of temper...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034513501877
更新日期：2013-11-01 00:00:00
abstract：:Periodontal data typically consist of observations made at multiple sites within each patient. Observations within a patient tend to be positively correlated; hence, standard statistical techniques that assume independence are invalid. Regression techniques for correlated data have been proposed; communicating results...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910308200705
更新日期：2003-07-01 00:00:00
abstract：:With the objective of contributing to the understanding of factors influencing the characteristics of dentition, dental observations from 429 children and adult highland people of western Bolivia are described. Various age, sex, ethnic, and village differences are observed in malocclusion, dental caries, periodontal d...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345780570030901
更新日期：1978-03-01 00:00:00
abstract：:A new type of hydraulic cement has been developed. This cement consists of a mixture of cement powder and setting agent powder and therefore has only to be kneaded with a little amount of water when being used. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345790580050601
更新日期：1979-05-01 00:00:00
abstract：:Experimental marginal leakage of high- and low-Cu amalgam restorations placed in acrylic teeth, where the cavities were untreated or painted with denatured collagen and/or a CaP slurry, was assessed after specimens were stored in a 1% NaCl solution for ten days and for one yr. All specimens stored for ten days showed ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630081801
更新日期：1984-08-01 00:00:00
abstract：:Previously, in vitro differentiation of odontoblasts was shown for dental pulp stem cells (DPSCs) transfected with bone morphogenetic protein-2 (Bmp2). For this study, we hypothesized that such cells also show potential for mineralized tissue formation in vivo. DPSCs were transfected with Bmp2 and seeded onto a cerami...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509346258
更新日期：2009-11-01 00:00:00
abstract：:Improved mechanical properties of resin composites have been reported to be a consequence of the addition of aldehyde to the resins. The objective of the present study was to examine whether this improvement could be attributed to an increased degree of conversion of double bonds. For this purpose, propanal was added ...
journal_title：Journal of dental research
pub_type： 杂志文章
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abstract：:Stereologic studies of trabecular architecture suggest that the pig mandibular condyle is strongest when loaded supero-inferiorly, and that stress is concentrated in the antero-inferior region (Teng and Herring, 1995). To test these hypotheses, we investigated the uni-axial mechanical properties of 22 pig mandibular c...
journal_title：Journal of dental research
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更新日期：1996-11-01 00:00:00
abstract：:A detailed understanding of the complexity of root canal systems is imperative to ensure successful root canal preparation. The aim of this study was to evaluate the potential and accuracy of a three-dimensional, non-destructive technique for detailing root canal geometry by means of high-resolution tomography. The an...
journal_title：Journal of dental research
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doi：10.1177/00220345000790060901
更新日期：2000-06-01 00:00:00
abstract：:Elemental analysis of two precious alloyceramic systems revealed the accumulation of Sn atoms within the interaction zone of couples subjected to a range of metal oxidation time; and varying total firing times. The source of Sn atoms which accumulated within the interaction zone was the opaque porcelain layer which co...
journal_title：Journal of dental research
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更新日期：1977-09-01 00:00:00
abstract：:The purpose of this work was to determine the influence of chemical food-simulating liquids on the wear of various commercial dental composite restoratives. In many cases, pre-conditioning the restoratives in these liquids for one week produced swelling of the polymer matrix and considerable surface damage. The result...
journal_title：Journal of dental research
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更新日期：1985-11-01 00:00:00
abstract：:Treatment of bisphosphonate-related osteonecrosis of the jaw (BRONJ) has posed significant challenges to maxillofacial surgeons because of the poor repair of BRONJ bone defects. Moreover, the pathological mechanisms remain unclear. Bone marrow stromal cells (BMSCs) play key roles during bone repair and bone regenerati...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034517691507
更新日期：2017-05-01 00:00:00
abstract：:Cyclic adenosine 3',5'-monophosphate (cAMP) concentrations and cellular distribution were studied in dental and periodontal tissues during tooth eruption in kittens. Although the mean levels of cAMP around developing teeth were similar in all the tissue samples, there were marked differences in cAMP stainability of ti...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560040801
更新日期：1977-04-01 00:00:00
abstract：:Genetic approaches are rapidly yielding new information about our sense of taste. This information comes from both molecular studies of genes encoding taste receptors and other taste-signaling components, and from studies of inherited variation in taste abilities. Our understanding of bitter taste has advanced by comb...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/154405910408300603
更新日期：2004-06-01 00:00:00
abstract：:Fungal infections in the oral cavity are mainly caused by C. albicans, but other Candida species are also frequently identified. They are increasing in prevalence, especially in denture-wearers and aging people, and may lead to invasive infections, which have a high mortality rate. Attachment to mucosal tissues and to...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034508329273
更新日期：2009-02-01 00:00:00
abstract：:We explored the potential to diagnose Zika virus (ZIKV) infection by analyzing peptides in saliva during a convalescent phase of infection, long after resolution of acute disease. A 25-y-old woman clinically diagnosed with Zika fever in the first trimester was enrolled with her dizygotic twins for a 3-mo postnatal sam...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034517723325
更新日期：2017-09-01 00:00:00
abstract：:Since 1935, various mechanisms have been suggested for the formation of subsurface lesions and, in particular, the surface layer covering enamel lesions. The relatively intact mineral-rich and porous surface layer is most likely caused by kinetic events. The suggested mineral-rich outer layer in sound enamel, the orga...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/00220345860650010201
更新日期：1986-01-01 00:00:00
abstract：:Caregivers' health literacy has emerged as an important determinant of young children's health care and outcomes. We examined the hypothesis that caregivers' health literacy influences children's oral-health-care-related expenditures. This was a prospective cohort study of 1,132 child/caregiver dyads (children's mean ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513484335
更新日期：2013-07-01 00:00:00
abstract：:The expression of antimicrobial peptides at epithelial surfaces such as skin, lung, and intestine is thought to provide protection against infection. Cathelicidin antimicrobial peptides are essential for the protection of skin against invasive bacterial infection. To determine if cathelicidins are also present in the ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910208101210
更新日期：2002-12-01 00:00:00
abstract：:Branching morphogenesis is essential for the formation of salivary glands, kidneys, lungs, and many other organs during development, but the mechanisms underlying this process are not adequately understood. Microarray and other gene expression methods have been powerful approaches for identifying candidate genes that ...
journal_title：Journal of dental research
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更新日期：2012-02-01 00:00:00
abstract：:Previous research, in which the bonding effectiveness of the 3 self-etch monomers HAEPA, EAEPA, and MAEPA was determined, showed that MAEPA was most effective. In this study, the molecular interactions of these monomers with hydroxyapatite and dentin were investigated by combining x-ray diffraction, infrared spectrosc...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510397197
更新日期：2011-05-01 00:00:00
abstract：:As an approach for improving the outcome and predictability of periodontal regenerative therapies, we have focused on determining the responses of cells within the local environment to putative regenerative factors. This study examined the effects of bone morphogenetic protein-2 (BMP-2) on murine cementoblasts in vitr...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910308200106
更新日期：2003-01-01 00:00:00
abstract：:Interleukin (IL)-23 is an essential cytokine involved in expansion of the Th17 lineage, which is associated with many immune-related destructive tissue diseases. We hypothesized that the IL-23-induced Th17 pathway plays a role in periodontal pathology and examined the expression of cytokines, and related molecules, in...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509339889
更新日期：2009-07-01 00:00:00
abstract：:The acquired dental pellicle helps prevent erosion, but the protection level is unknown. This in situ study tested whether a two-hour pellicle protects against different erosive challenges by orange juice. Subjects wore palatal appliances loaded with either enamel or dentin specimens. Pellicle was allowed to form, or ...
journal_title：Journal of dental research
pub_type： 杂志文章,随机对照试验
doi：10.1177/154405910608500706
更新日期：2006-07-01 00:00:00
abstract：:Obesity is a widespread chronic inflammatory disorder characterized by an increased overall disease burden and significant association with periodontitis. The aim of this prospective clinical cohort study was to investigate the effect of obesity on orthodontic tooth movement. Fifty-five adolescent patients (27 males, ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034516688448
更新日期：2017-05-01 00:00:00
abstract：:Although a large body of scientific literature shows that background color and luminance affect color perception, previous measurements of tooth color difference thresholds have not taken the effects of viewing context into account. The present study tested the hypothesis that differences in skin/gingival color influe...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510376772
更新日期：2010-11-01 00:00:00
abstract：:Zirconia-based restorations often fracture from chipping and/or delamination of the porcelain veneers. We hypothesized that veneer chipping/delamination is a result of the propagation of near-contact-induced partial cone cracks on the occlusal surface under mastication. Masticatory loading involves the opposing tooth ...
journal_title：Journal of dental research
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doi：10.1177/154405910808701210
更新日期：2008-12-01 00:00:00
abstract：:Heterozygous mutations in the RUNX2 (CBFA1) gene cause cleidocranial dysplasia, characterized by multiple supernumerary teeth. This suggests that Runx2 inhibits successional tooth formation. However, in Runx2 knockout mice, molar development arrests at the late bud stage, and lower molars are more severely affected th...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910508400206
更新日期：2005-02-01 00:00:00
abstract：:As a major intracellular degradation and recycling machinery, autophagy plays an important role in maintaining cellular homeostasis and remodeling during normal development. Our previous study showed that fluorapatite (FA) crystal-coated electrospun polycaprolactone (PCL) was capable of inducing differentiation and mi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034516636852
更新日期：2016-06-01 00:00:00
abstract：:Auto-degradation of collagen matrices occurs within hybrid layers created by contemporary dentin bonding systems, by the slow action of host-derived matrix metalloproteinases (MMPs). This study tested the null hypothesis that there are no differences in the activities of MMP-2 and -9 after treatment with different etc...
journal_title：Journal of dental research
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doi：10.1177/0022034512467034
更新日期：2013-01-01 00:00:00
