Abstract:
:This randomized controlled trial aimed to evaluate the duration and outcome quality of orthodontic treatment with a customized fixed appliance system versus a noncustomized system. Patients ( n = 180) were randomized and received orthodontic treatment with the Insignia customized orthodontic system or the Damon Q noncustomized orthodontic system. The allocation sequence was concealed using identical, sequentially numbered, opaque, sealed envelopes. Patients with nonextraction treatment plans were treated by 2 equally experienced orthodontists. Pretreatment and posttreatment plaster casts were made for each patient, and the models were rated using the Peer Assessment Rating (PAR) score. Planning time, treatment duration, and numbers of loose brackets, visits, and complaints were recorded. The examined null hypothesis was that the customized appliance system was not associated with significantly ( P < 0.05) shorter treatment duration compared to a noncustomized appliance. We analyzed 85 patients in the customized group and 89 in the noncustomized group. Treatment duration was 1.29 ± 0.35 y in the customized group and 1.24 ± 0.37 y in the noncustomized group. In the customized group, the PAR score was 23.32 ± 9.15 pretreatment and 5.38 ± 3.75 posttreatment. In the noncustomized group, the PAR score was 21.84 ± 7.95 pretreatment and 5.93 ± 3.58 posttreatment. None of these outcomes significantly differed between groups. On the other hand, the orthodontist had a significant effect on treatment duration, quality of treatment outcome, and number of visits ( P < 0.05). A higher PAR score pretreatment was associated with increased treatment duration, posttreatment PAR, and number of visits ( P < 0.05). Compared to the noncustomized group, the customized group had more loose brackets, a longer planning time, and more complaints ( P < 0.05). The customized orthodontic system was not associated with significantly reduced treatment duration, and treatment quality was comparable between the 2 systems ( ClinicalTrials.gov : NCT01268852).
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Penning EW,Peerlings RHJ,Govers JDM,Rischen RJ,Zinad K,Bronkhorst EM,Breuning KH,Kuijpers-Jagtman AMdoi
10.1177/0022034517720913subject
Has Abstractpub_date
2017-12-01 00:00:00pages
1498-1504issue
13eissn
0022-0345issn
1544-0591journal_volume
96pub_type
杂志文章,随机对照试验abstract::The benefits of early orthodontic treatment are continuously discussed, but studies are few. We examined whether definite need for orthodontic treatment could be eliminated in public health care by systematically focusing on early intervention. One age cohort living in a rural Finnish municipality (N = 85) was regular...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910808700604
更新日期:2008-06-01 00:00:00
abstract::Cardiovascular disease is a common cause of morbidity and premature mortality. Cardiovascular disease can be prevented when risk factors are identified early. Calcified carotid artery atheromas (CCAAs), detected in panoramic radiographs, and periodontitis have both been associated with increased risk of cardiovascular...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034519885362
更新日期:2020-01-01 00:00:00
abstract::Dimensional alterations of the facial bone wall following tooth extractions in the esthetic zone have a profound effect on treatment outcomes. This prospective study in 39 patients is the first to investigate three-dimensional (3D) alterations of facial bone in the esthetic zone during the initial 8 wks following flap...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/0022034513506713
更新日期:2013-12-01 00:00:00
abstract::Dental diseases are now viewed as a consequence of a deleterious shift in the balance of the normally stable resident oral microbiome. It is known that frequent carbohydrate consumption or reduced saliva flow can lead to caries, and excessive plaque accumulation increases the risk of periodontal diseases. However, whe...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034517742139
更新日期:2018-04-01 00:00:00
abstract::Diet is recognized as one of the most important factors affecting the equilibrium of the oral bacterial flora. Studies related to dental caries development have focused mainly on the effect of carbohydrates. In the present work, using swabbing coupled with an immuno-colony-blot assay, we followed the indigenous oral b...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345900690030801
更新日期:1990-03-01 00:00:00
abstract::The aim of the present study was to describe the patterns of dental fluorosis in the primary and the permanent dentition of children born and reared in two different fluoridated areas, one in which powdered milk suspended in tap water was commonly used (Narssaq, Greenland: 1.1 ppm fluoride in the water) and one in whi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670050501
更新日期:1988-05-01 00:00:00
abstract::TWIST1 plays a crucial role in dentinogenesis, and its activity depends on both a dimerization partner selection and phosphorylation. Other factors, like Id proteins, can affect the availability of dimerization partners for TWIST1, subsequently leading to diverse biological outcomes. The purpose of this study was to e...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514530164
更新日期:2014-06-01 00:00:00
abstract::Periodontitis is a chronic inflammatory disease induced by a biofilm that forms on the tooth surface. Increased periodontal disease is associated with aging. We investigated the effect of aging on challenge by oral pathogens, examining the host response, colonization, and osteoclast numbers in aged versus young mice. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515625962
更新日期:2016-04-01 00:00:00
abstract::Resin-bonded bridges may replace missing teeth and act as splints in periodontal treatment. The objective of this study was to investigate the etch pattern after electrolytic etching of selected Co-Cr alloys in hydrochloric acid and to assess the changes in alloy composition after different etching times. The alloys i...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660091301
更新日期:1987-09-01 00:00:00
abstract::With the objective of contributing to the understanding of factors influencing the characteristics of dentition, dental observations from 429 children and adult highland people of western Bolivia are described. Various age, sex, ethnic, and village differences are observed in malocclusion, dental caries, periodontal d...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570030901
更新日期:1978-03-01 00:00:00
abstract::Gingival epithelium is a site of active trafficking of Langerhans cells (LCs), while the lamina propria in chronic periodontitis (CP) contains CD83+ mature dendritic cells (mDCs) and CD4+ T-cells. The immune cells that contribute to the mDCs, and whether mDCs engage with T-cells in situ, are unclear. Using several imm...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200915
更新日期:2003-09-01 00:00:00
abstract::Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790010701
更新日期:2000-01-01 00:00:00
abstract::Frequent consumption of cariogenic foods and bacterial infection are risk factors for early childhood caries (ECC). This study hypothesized that a short diet survey focused on frequency of foods, categorized by putative cariogenicity, would differentiate severe ECC (S-ECC) from caries-free children. Children's diets w...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510376543
更新日期:2010-11-01 00:00:00
abstract::The aim of the present in vitro experiments was to determine whether the protection of enamel by topically applied fluoride against demineralization by bacterial acids would depend on the fluoride sensitivity of the bacteria. Glucose-agarose gel suspensions of fluoride-sensitive and fluoride-resistant mutans streptoco...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720080401
更新日期:1993-08-01 00:00:00
abstract::The purpose of the study was to determine the exposure times needed to harden a light-activated composite cement through various thicknesses of porcelain. A negative exponential model was developed with which the relative hardness of a composite could be predicted from the product of the exposure time and the square r...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680030801
更新日期:1989-03-01 00:00:00
abstract::Recent functional animal studies have reported that the motor control of masticatory muscle function is bilaterally guided by both hemispheres, which may fundamentally differ from the cortical control of limb muscle function. In this study, we investigated whether unilateral cortical brain infarction induces different...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345990780120701
更新日期:1999-12-01 00:00:00
abstract::Recent studies have shown that the extent of hydrolysis by plaque of the trypsin substrate, N-benzoyl-DL-arginine-2-naphthylamide (BANA), correlates with the numbers and proportions of spirochetes in subgingival plaque samples, and appears to be an indicator of clinical disease. In this study, BANA hydrolysis by subgi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670121201
更新日期:1988-12-01 00:00:00
abstract::Hereditary diseases affecting the skeleton are heterogeneous in etiology and severity. Though many of these conditions are individually rare, the total number of people affected is great. These disorders often include dental-oral-craniofacial (DOC) manifestations, but the combination of the rarity and lack of in-depth...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034514529150
更新日期:2014-07-01 00:00:00
abstract::The human patched gene (PTCH) functions in both embryologic development and tumor suppression. PTCH mutations have been found in odontogenic keratocysts. However, the expression and localization of the protein product of the gene have not been determined in odontogenic tumors and cysts. We investigated 68 odontogenic ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0810757
更新日期:2002-11-01 00:00:00
abstract::Previous findings from studies utilizing human labial and palatine minor salivary glands are reviewed. These studies took histopathological, biochemical, and ultrastructural approaches, and focused on control and diseased glands. Disease-oriented summarization are used, and control results are discussed in the context...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660s108
更新日期:1987-02-01 00:00:00
abstract::Smoking has been established as an important risk factor for periodontal disease and tooth loss. The purpose of this study was a prospective evaluation of the effects of smoking on dental care utilization and its costs, based on data from 5712 males aged 20-59 yrs. Age, dental health behavior, and history of diabetes ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034508327523
更新日期:2009-01-01 00:00:00
abstract::Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects, HPP causes dental...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515573273
更新日期:2015-05-01 00:00:00
abstract::The objective of this study was to assess the relative effects of age and oral hygiene on the progression of periodontitis by estimating incidence from age-specific prevalence. This study analyzed data from a representative national sample of 14,690 dentate Americans, aged from 15 to 74, seen in the first National Hea...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660010201
更新日期:1987-01-01 00:00:00
abstract::Wall-to-wall (WTW) polymerization contraction of filled and unfilled chemically and photo-initiated resins was studied in relation to the WTW distance. In an experimental set-up, the resins were bonded to two opposing disks, and the axial (WTW) displacement resulting from the polymerization shrinkage was measured cont...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680010701
更新日期:1989-01-01 00:00:00
abstract::A major extracellular protein of cultured adult human gingival fibroblasts was shown to be fibronectin by indirect immunofluorescence, lactoperoxidase catalyzed iodination and metabolic radiolabeling. Fibronectin preparations from these cells possessed the biological properties of agglutination of sheep red blood cell...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590031301
更新日期:1980-03-01 00:00:00
abstract::In vitro wear data were determined for nine experimental composites and compared with two-year clinical data. The in vitro tests included single-pass wear and two-body abrasion. The in vivo data were obtained between 1978 and 1980 for 54 class 2 posterior composite restorations in 25 patients. Correlations between the...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620101801
更新日期:1983-10-01 00:00:00
abstract::The aim of this study was to test the potential of liposomes as drug carriers to the ulcerated oral mucosa. Radioactive triamcinolone acetonide palmitate (3H-TRMAp) was encapsulated in large multilamellar lipid vesicles and served as the test lotion. 3H-TRMAp in solution served as control. Forty-six hamsters were divi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650090501
更新日期:1986-09-01 00:00:00
abstract::The main purpose of this paper is to review the various methods used for evaluation of fluoride retention in saliva, plaque, and enamel following application of topical anti-caries treatments such as F dentifrices and F mouthwashes. Such methods monitor delivery of fluoride to the site of action, the mouth, and so can...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/002203459207100S29
更新日期:1992-04-01 00:00:00
abstract::Proteolytic hydrolysis of casein and porcine or bovine glycoproteins by S mutans was demonstrated in the present study. Caseinolytic activity was found in both the soluble contents of the cells and the cellular debris after rupture of the cells. However, caseinolytic activity could not be demonstrated after growth in ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550031701
更新日期:1976-05-01 00:00:00
abstract::Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034516645796
更新日期:2016-08-01 00:00:00