Abstract：
:The reaction of the microvasculature in the periodontal ligament to mechanical pressure is considered a very important phenomenon with respect to the biological background to orthodontic tooth movement. For clarification of the microvascular reaction to mechanical pressure, an experimental model that incorporated a hamster cheek pouch was established. This in vivo model solves some of the problems of other experimental models of the microvasculature of the periodontal ligament. Blood plasma permeation in this model was examined by means of a blue dye (pontamine sky blue), and histological observation was performed by light and transmission electron microscopy. Increased vascular permeability was observed within 30 min after removal of the mechanical stimulation. The threshold weight resulting in dye leakage was between 1 and 5 g applied for 60 min. From the histological observations, some large gaps between the endothelial cells in venules were found, while most basement membranes remained undisturbed. These observations suggest that the plasma leakage was due to mild traumatic injury to the endothelial cells. Both leukocytes and platelets were observed in the gaps between the endothelial cells in the venule. These types of microvascular reactions to mechanical pressure could initiate tissue changes in the periodontal ligament during orthodontic tooth movement.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Iida J,Inage S,Kurihara S,Miura Fdoi
10.1177/00220345920710060701keywords:
subject
Has Abstractpub_date
1992-06-01 00:00:00pages
1304-9issue
6eissn
0022-0345issn
1544-0591journal_volume
71pub_type
杂志文章abstract：:The purpose of this investigation was to determine the water sorption and solubility, as well as the filler composition and extent of chemical degradation in water, of eight different posterior composites. With one exception, the materials with the largest quantity of fillers had the least water sorption and solubilit...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650110601
更新日期：1986-11-01 00:00:00
abstract：:We analyzed the flow rate and composition of paraffin-stimulated whole saliva samples from 35 adult diabetic patients and their age- and sex-matched, non-diabetic, clinically healthy controls. All patients had insulin-dependent diabetes (IDDM) with a mean (+/- S.D.) duration of 14.0 +/- 9.1 years. The saliva analysis ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650011101
更新日期：1986-01-01 00:00:00
abstract：:In an attempt to make a dynamic study of the isoelectric point and the chargeability of human dental enamel, an electrochemical approach was utilized. Zeta potential of three kinds of the enamel was measured by a streaming potential method. As a result, these isoelectric points could be decided. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345780570022701
更新日期：1978-02-01 00:00:00
abstract：:The use of electric current during the application of etch-and-rinse adhesive systems has been recently claimed to increase bonding of etch-and-rinse adhesives by enhancing substrate impregnation. The null hypothesis tested in this study was that electrically assisted application has no effect on bond strength of self...
journal_title：Journal of dental research
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doi：10.1177/154405910608501205
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abstract：:The effects of various additives on the setting of the glass-ionomer cement system was studied by means of cone and plate viscometry. The action of (+)-tartaric acid, the most important additive, on the setting reaction depended on its concentration. Low concentrations accelerated the development of viscosity of the c...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670120101
更新日期：1988-12-01 00:00:00
abstract：:Lipopolysaccharide (LPS) has been shown to be a prominent pathogenic factor in inflammatory bone loss. However, knowledge of the mechanisms involved is limited. The role of the SDF-1/CXCR4 (Stromal-derived factor-1 and its unique chemokine receptor) axis in LPS-induced bone loss has not been studied. The aim of this s...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510379019
更新日期：2011-02-01 00:00:00
abstract：:Resin composites must be improved if they are to overcome the high failure rates in large stress-bearing posterior restorations. This study aimed to improve wear resistance via nano-silica-fused whiskers. It was hypothesized that nano-silica-fused whiskers would significantly improve composite mechanical properties an...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910408301208
更新日期：2004-12-01 00:00:00
abstract：:In this study, we sought to determine the association between tooth agenesis and DNA sequence variation in the genes MSX1 and PAX9 in an ethnically diverse human population. Since cleft lip/palate is also associated with both tooth agenesis and the gene TGFA, we included TGFA in the analysis as well. Cheek swab sample...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910408300913
更新日期：2004-09-01 00:00:00
abstract：:In an earlier paper on bench-scale simulation of the caries process, it was shown that the passage of ions through ion-permselective barriers could have profound effects on the composition of the solution within the "lesion" at steady state. As indicated in earlier papers, these changes are produced by unequal rates o...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650090201
更新日期：1986-09-01 00:00:00
abstract：:The acquired dental pellicle helps prevent erosion, but the protection level is unknown. This in situ study tested whether a two-hour pellicle protects against different erosive challenges by orange juice. Subjects wore palatal appliances loaded with either enamel or dentin specimens. Pellicle was allowed to form, or ...
journal_title：Journal of dental research
pub_type： 杂志文章,随机对照试验
doi：10.1177/154405910608500706
更新日期：2006-07-01 00:00:00
abstract：:Incisors of Mg-deficient rats showed a marked inhibition of eruption and a decrease in mitoses of apical tissues. Cortisone administration resulted in some increase in eruption rate and cell division though these remained below the values of Mg-supplemented controls. An improvement in gross condition and a less severe...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560122901
更新日期：1977-12-01 00:00:00
abstract：:Symphyseal secondary cartilage is important for mandibular development, but the molecular mechanisms underlying its formation remain largely unknown. Here we asked whether Indian hedgehog (Ihh) regulates symphyseal cartilage development and growth. By embryonic days 16.5 to 18.5, Sox9-expressing chondrocytes formed wi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510397836
更新日期：2011-05-01 00:00:00
abstract：:Frequent consumption of cariogenic foods and bacterial infection are risk factors for early childhood caries (ECC). This study hypothesized that a short diet survey focused on frequency of foods, categorized by putative cariogenicity, would differentiate severe ECC (S-ECC) from caries-free children. Children's diets w...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510376543
更新日期：2010-11-01 00:00:00
abstract：:Insulin resistance is one of the critical pathogeneses of type 2 diabetes mellitus (T2DM). Elevated levels of plasma branched-chain amino acids (BCAAs) are associated with insulin resistance. Recent studies have demonstrated the role of Porphyromonas gingivalis in the development of insulin resistance. However, the me...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520911037
更新日期：2020-07-01 00:00:00
abstract：:Numerous studies have demonstrated that many older adults have problems chewing, pain, difficulties in eating, and problems in social relationships because of oral disorders. However, it is not clear if these functional and psychosocial outcomes affect broader psychological well-being and life satisfaction. Consequent...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345000790041301
更新日期：2000-04-01 00:00:00
abstract：:An in vitro model has been developed for measurement of initial attachment of 3H-labeled human gingival fibroblasts (HGF) and periodontal ligament cells (HPDL cells) to sieved dentin powder. Reproducible attachment was obtained and was closely related to the number of plated cells, the amount of dentin powder, the tem...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720030901
更新日期：1993-03-01 00:00:00
abstract：:The aim of this systematic review and network meta-analysis was to summarize the direct and indirect clinical evidence on the effectiveness of professionally applied and self-applied topical fluorides in preventing dental root caries. Controlled clinical trials with any follow-up duration were included. MEDLINE, PubMe...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520906384
更新日期：2020-05-01 00:00:00
abstract：:Physico-chemical investigations of enamel from deciduous teeth of a small number of children with and without pre-natal fluoride supplementation (PNF) exhibited the following differences between the PNF and non-PNF enamel, with the former showing: (a) more homogeneous and less extensive patterns of acid-etching; (b) d...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345850640031601
更新日期：1985-03-01 00:00:00
abstract：:The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts and cementoblasts. We hypothesized that stem cells may be present in the DF and be capable of differentiating into cells of the periodontium. Stem cells ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910808700801
更新日期：2008-08-01 00:00:00
abstract：:Components of resin materials may damage DNA, leading to genetic alterations in mammalian cells. Here, monomers were analyzed for the induction of chromosomal aberrations indicated by micronuclei induced in V79 cells. A dose-related increase in the numbers of micronuclei was observed with triethyleneglycol dimethacryl...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345010800070401
更新日期：2001-07-01 00:00:00
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journal_title：Journal of dental research
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journal_title：Journal of dental research
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doi：10.1177/00220345840630101501
更新日期：1984-10-01 00:00:00
abstract：:Extracellular vesicles (EVs), several tens to hundreds of nanometers in size, are vesicles secreted by cells for intercellular communication. EVs released from mesenchymal stem cells (MSC-EVs) have the potential to treat multiple diseases. This study aimed to determine the effects of MSC-EVs on bisphosphonate-related ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520906793
更新日期：2020-05-01 00:00:00
abstract：:Sjögren's syndrome is a common autoimmune rheumatic disease. The most common symptoms of Sjögren's syndrome are extreme tiredness, along with dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia). Saliva plays an essential role in numerous functions of the mouth. Xerostomia can be caused by medications, chr...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
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更新日期：2008-04-01 00:00:00
abstract：:Lactoferrin is one of a number of multifunctional proteins that are present in or on all mucosal surfaces throughout the body. Levels of lactoferrin are consistently elevated in inflammatory diseases such as arthritis, inflammatory bowel diseases, corneal disease, and periodontitis. Single-nucleotide polymorphisms (SN...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
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更新日期：2015-06-01 00:00:00
abstract：:The goal of nonrestorative or non- and microinvasive caries treatment (fluoride- and nonfluoride-based interventions) is to manage the caries disease process at a lesion level and minimize the loss of sound tooth structure. The purpose of this systematic review and network meta-analysis was to summarize the available ...
journal_title：Journal of dental research
pub_type： 杂志文章,meta分析
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更新日期：2019-01-01 00:00:00
abstract：:The diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection relies on the detection of viral RNA by real-time reverse transcription polymerase chain reaction (rRT-PCR) performed with respiratory specimens, especially nasopharyngeal swabs. However, this procedure requires specialized medical...
journal_title：Journal of dental research
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更新日期：2021-02-01 00:00:00
abstract：:Intracystic fluid pressure is thought to be involved in odontogenic cyst growth. In this study, we investigated the effects of positive pressure on the expression of interleukin-1alpha (IL-1alpha), matrix metalloproteinases (MMPs), and prostaglandin E2 (PGE2) in odontogenic keratocysts to determine whether this pressu...
journal_title：Journal of dental research
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更新日期：2005-10-01 00:00:00
abstract：:The oral microbiome is one of the most stable ecosystems in the body and yet the reasons for this are still unclear. As well as being stable, it is also highly diverse which can be ascribed to the variety of niches available in the mouth. Previous studies have focused on the microflora in disease-either caries or peri...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034520915486
更新日期：2020-06-01 00:00:00
abstract：:Caries of the permanent first molars of 5-year-old children was found to be associated with caries of their diciduous teeth. The sample consisted of 220 children whose permanent first molars had erupted. They were selected out of 965 children who were a representative sample of children attending compulsory kindergart...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345760550062001
更新日期：1976-11-01 00:00:00
