Endothelin receptor-mediated responses in trigeminal ganglion neurons.

abstract：:Recent advances in molecular biology have facilitated analyses of the oral microbiome ("Who are they?"); however, its functions (e.g., metabolic activities) are poorly understood ("What are they doing?"). This review aims to summarize our current understanding of the metabolism of the oral microbiome. Saccharolytic ba...

journal_title：Journal of dental research

authors： Takahashi N

更新日期：2015-12-01 00:00:00

abstract：:Dispersed salivary acini isolated from the rat submandibular gland by enzymatic digestion were used to study the effects of alpha-receptor stimulation on transmembrane transport of 36Cl. In the absence of secretagogue, the tracer accumulated in the cells in a time-dependent manner until a steady-state content of 6.8 +...

journal_title：Journal of dental research

authors： Martinez JR,Reed P

更新日期：1988-03-01 00:00:00

abstract：:Since edentate subjects have a reduced masticatory function, it can be expected that the morphology of the cancellous bone of their mandibular condyles has changed according to the altered mechanical environment. In the present study, the morphology of cylindrical cancellous bone specimens of the mandibular condyles o...

journal_title：Journal of dental research

authors： Giesen EB,Ding M,Dalstra M,van Eijden TM

更新日期：2004-03-01 00:00:00

abstract：:The range of substrates transported by the sugar-binding protein-dependent msm (multiple sugar metabolism) system of S. mutans was investigated. By determining the ability of unlabeled sugar to compete with radiolabeled melibiose transport, we have demonstrated that the transported sugars included a number of carbohyd...

journal_title：Journal of dental research

authors： Tao L,Sutcliffe IC,Russell RR,Ferretti JJ

更新日期：1993-10-01 00:00:00

abstract：:Various etching methods are examined with respect to their ability to induce the surface nucleation and growth of fluorapatite from solutions of low, sustained supersaturation with respect to hydroxyapatite and fluorapatite. The constant composition kinetics method enables the rates of remineralization to be precisely...

journal_title：Journal of dental research

authors： Amjad Z,Koutsoukos PG,Nancollas GH

更新日期：1982-09-01 00:00:00

abstract：:Dynamic changes of pulpal blood flow (PBF) and gingival blood flow (GBF) induced by intra-venous injection of two kinds of vasoactive drugs were observed in dogs by means of Laser Doppler Velocimetry. Intra-venous injection of norepinephrine caused PBF to increase, corresponding to the blood pressure (BP) increase, wh...

journal_title：Journal of dental research

authors： Sasano T,Kuriwada S,Sanjo D

更新日期：1989-05-01 00:00:00

abstract：:Decisions to replace existing restorations are often based on clinical findings of margin discrepancies and other restoration defects. Previous studies have suggested that such findings do not correlate well with the actual presence of secondary caries, and that treatment should be deferred until caries is clinically ...

journal_title：Journal of dental research

authors： Hewlett ER,Atchison KA,White SC,Flack V

更新日期：1993-12-01 00:00:00

abstract：:Strength and durability of the dentin-acrylic resin joint cemented with 2-cyanoacrylate esters were studied. Maximum adhesion is obtained with isobutyl 2-cyanoacrylate after 1% acid pretreatment of the dentin. Hydrolytic stability is somewhat improved by addition of polymer to the adhesive or coating around the joint....

journal_title：Journal of dental research

authors： Brauer GM,Jackson JA,Termini DJ

更新日期：1979-09-01 00:00:00

abstract：:We previously demonstrated that an anti-caries DNA vaccine intranasally administered with recombinant flagellin protein as a mucosal adjuvant enhanced salivary IgA response and conferred better protection against caries. However, the relatively weak immunogenicity of DNA vaccines and the necessity for a large quantity...

journal_title：Journal of dental research

authors： Sun Y,Shi W,Yang JY,Zhou DH,Chen YQ,Zhang Y,Yang Y,He BX,Zhong MH,Li YM,Cao Y,Xiao Y,Li W,Yu J,Li YH,Fan MW,Yan HM

更新日期：2012-10-01 00:00:00

abstract：:In the absence of active pulmonary disease, mycobacterial infection frequently causes arthritis and can be considered to initiate autoimmune diseases such as rheumatoid arthritis. Temporomandibular disorder (TMD) is a disease in which pain and impaired mandibular movement appear to arise directly from degenerative or ...

journal_title：Journal of dental research

authors： Adachi N,Matsumoto S,Tokuhisa M,Kobayashi K,Yamada T

更新日期：2000-10-01 00:00:00

abstract：:One-step incomplete excavation seals caries-affected dentin under a restoration and appears to be advantageous in the treatment of deep lesions. However, it is impossible to discriminate radiographically between intentionally left, arrested lesions and overlooked or active lesions. This diagnostic uncertainty decrease...

journal_title：Journal of dental research

authors： Schwendicke F,Meyer-Lueckel H,Schulz M,Dörfer CE,Paris S

更新日期：2014-06-01 00:00:00

abstract：:The diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection relies on the detection of viral RNA by real-time reverse transcription polymerase chain reaction (rRT-PCR) performed with respiratory specimens, especially nasopharyngeal swabs. However, this procedure requires specialized medical...

journal_title：Journal of dental research

authors： Azzi L,Maurino V,Baj A,Dani M,d'Aiuto A,Fasano M,Lualdi M,Sessa F,Alberio T

更新日期：2021-02-01 00:00:00

abstract：:Protease-activated receptors (PARs) are G protein-coupled receptors, which are activated by proteolytical cleavage of the amino-terminus and act as sensors for extracellular proteases. We hypothesized that PAR-1 and PAR-2 can be modulated by inflammatory stimulus in human dental pulp cells. PAR-1 and PAR-2 gene expres...

journal_title：Journal of dental research

authors： Alvarez MMP,Moura GE,Machado MFM,Viana GM,de Souza Costa CA,Tjäderhane L,Nader HB,Tersariol ILS,Nascimento FD

更新日期：2017-12-01 00:00:00

abstract：:Periodontal data typically consist of observations made at multiple sites within each patient. Observations within a patient tend to be positively correlated; hence, standard statistical techniques that assume independence are invalid. Regression techniques for correlated data have been proposed; communicating results...

journal_title：Journal of dental research

authors： Panageas KS,Begg MD,Grbic JT,Lamster IB

更新日期：2003-07-01 00:00:00

abstract：:A previously reported technique for staining areas of degradation in dental composite restorations was evaluated in 51 removed restorations. The staining reagent was silver nitrate, which penetrated the degraded subsurface as ionic silver and was subsequently developed into colored deposits of metallic silver. Several...

journal_title：Journal of dental research

authors： Mair LH

更新日期：1991-03-01 00:00:00

abstract：:We determined the exposure to mercury from dental amalgam by comparison of blood levels of mercury before and after removal of all amalgams from ten subjects. Baseline concentrations of mercury in whole blood were measured weekly for four to 18 weeks (median = 6.6 weeks) prior to removal. All amalgams were removed in ...

journal_title：Journal of dental research

authors： Snapp KR,Boyer DB,Peterson LC,Svare CW

更新日期：1989-05-01 00:00:00

abstract：:1. A method has been developed and described for obtaining accurate thermal diffusivity values for dental cements and other restorative materials. This method employs specimens of a short cylindrical geometry which are readily fabricated from simply-constructed molds. 2. Results obtained for polycarboxylate and glass-...

journal_title：Journal of dental research

authors： Watts DC,Smith R

更新日期：1981-12-01 00:00:00

abstract：:It has often been hypothesized that a large tongue leads to an enlargement of the mandible and therefore contributes to the development of mandibular prognathism. We examined (1) whether the tongue volume in human subjects with mandibular prognathism was larger than that in subjects with good occlusion and (2) whether...

journal_title：Journal of dental research

authors： Yoo E,Murakami S,Takada K,Fuchihata H,Sakuda M

更新日期：1996-12-01 00:00:00

abstract：:Diabetes mellitus is associated with depression of natural defenses against infection and increases the risk of periodontal disease. However, the effects of diabetes on periradicular tissue, which differs structurally from periodontal tissue, are not known. In this study, we evaluated the effects of type 2 diabetes on...

journal_title：Journal of dental research

authors： Iwama A,Nishigaki N,Nakamura K,Imaizumi I,Shibata N,Yamasaki M,Nakamura H,Kameyama Y,Kapila Y

更新日期：2003-04-01 00:00:00

abstract：:In periodontal surgery, healing after guided tissue regeneration (GTR) may be explained by differences in functional activities of gingival and periodontal ligament fibroblasts (GF and PDLF). Several studies in vitro have supported this hypothesis, but much remains to be defined. In the present work, gingival and peri...

journal_title：Journal of dental research

authors： Giannopoulou C,Cimasoni G

更新日期：1996-03-01 00:00:00

abstract：:The aim of this study was to test the potential of liposomes as drug carriers to the ulcerated oral mucosa. Radioactive triamcinolone acetonide palmitate (3H-TRMAp) was encapsulated in large multilamellar lipid vesicles and served as the test lotion. 3H-TRMAp in solution served as control. Forty-six hamsters were divi...

journal_title：Journal of dental research

authors： Harsanyi BB,Hilchie JC,Mezei M

更新日期：1986-09-01 00:00:00

abstract：:Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the...

journal_title：Journal of dental research

authors： Lough KJ,Byrd KM,Spitzer DC,Williams SE

更新日期：2017-10-01 00:00:00

abstract：:In the past decade, medical genetic research has generated multiple discoveries, many of which were obtained via genome-wide association studies (GWASs). A major GWAS finding is that the majority of risk variants for complex traits map to noncoding regions. This has resulted in a paradigm shift in terms of the interpr...

journal_title：Journal of dental research

authors： Thieme F,Ludwig KU

更新日期：2017-10-01 00:00:00

abstract：:Rat parotid secretory granule membranes were examined for the presence of calcium-dependent protein kinase activities and kinase substrates. Protein kinase C (C-kinase), which is stimulated by certain phospholipids, was present in the membranes, as indicated by its ability to catalyze the phosphorylation of histone. T...

journal_title：Journal of dental research

authors： Dowd F,Watson EL,Lau YS,Justin J,Pasieniuk J,Jacobson KL

更新日期：1987-02-01 00:00:00

abstract：:Studies on mechanisms underlying the differentiation of dental pulp stem cells are critical for the understanding of the biology of odontogenesis and for dental tissue engineering. Here, we tested the hypothesis that stem cells from exfoliated deciduous teeth (SHED) differentiate into functional odontoblasts and endot...

journal_title：Journal of dental research

authors： Sakai VT,Zhang Z,Dong Z,Neiva KG,Machado MA,Shi S,Santos CF,Nör JE

更新日期：2010-08-01 00:00:00

abstract：:The initiator of calculus matrix calcification, in vitro, was isolated. Crude phospholipid, known to contain the factor, was separated into five fractions by column chromatography. A single protein-containing fraction induced apatite formation during incubation. The nucleating fraction was indentified as a proteolipid...

journal_title：Journal of dental research

authors： Ennever J,Vocel JJ,Riggan LJ,Paloski SB

更新日期：1977-02-01 00:00:00

abstract：:Dental plaque collected from the label aspect of the anterior dentition of children harbored Neisseria that synthesized an extracellular iodophilic polysaccharide (EIP) from sucrose. Gas chromatograms of fully-acetylated EIP derivatives indicated that glucose (97%) and galactose (3%) were the only monosaccharide const...

journal_title：Journal of dental research

authors： Ruby JD,Shirey RE,Gerencser VF,Stelzig DA

更新日期：1982-05-01 00:00:00

abstract：:Modulation of the phosphoinositide signal transduction pathway by arachidonic acid (AA) in collagenase-dispersed rat submandibular acinar cells was investigated. The muscarinic agonist, carbachol, stimulated PIP2 hydrolysis and the generation of IP3 to five-fold the control levels. This response was inhibited by 75% o...

journal_title：Journal of dental research

authors： Chung HC,Fleming N

更新日期：1992-08-01 00:00:00

abstract：:Smoking is a major risk of periodontal diseases. At the site of first contact, the gingiva is exposed to aromatic amines and polycyclic hydrocarbons. These are metabolized by the N-acetyltransferases (NAT), leading to local detoxification and/or activation reactions contributing to the risk of periodontal destruction ...

journal_title：Journal of dental research

authors： Meisel P,Giebel J,Peters M,Foerster K,Cascorbi I,Wulff K,Fanghaenel J,Kocher T

更新日期：2002-05-01 00:00:00

abstract：:Occlusal alterations may result in changes in the functional performance of masticatory muscles. In this study, we set up an experimental model in rats to examine whether masticatory muscle abnormalities occur after a malocclusion is induced. Rats underwent unilateral amputation of the molar cusps to simulate an occlu...

journal_title：Journal of dental research

authors： Bani D,Bani T,Bergamini M

更新日期：1999-11-01 00:00:00