Expression of N-acetyltransferases in periodontal granulation tissue.

abstract：:Despite the recognized link between aging and cancer, most preclinical studies in experimental tumor models are conducted with 6- to 8-wk-old rodents. The goal of the present study was to examine the impact of age on tumor incidence, growth, and microenvironmental characteristics in mouse models of head and neck squam...

journal_title：Journal of dental research

authors： Vincent-Chong VK,DeJong H,Rich LJ,Patti A,Merzianu M,Hershberger PA,Seshadri M

更新日期：2018-10-01 00:00:00

abstract：:Several studies have shown that surgical detachment of marginal gingiva close to the cervical cementum of molar teeth in a rat mandible is a distinct stimulus for alveolar bone resorption. Recently, we found that P2X4, an ATP-receptor, is significantly up-regulated in marginal gingival cells soon after surgery. We hyp...

journal_title：Journal of dental research

authors： Binderman I,Bahar H,Jacob-Hirsch J,Zeligson S,Amariglio N,Rechavi G,Shoham S,Yaffe A

更新日期：2007-02-01 00:00:00

abstract：:Cytotoxicity of fine cut amalgam was persistent until 24 hours after trituration in vitro, whereas cytotoxicity of spherical amalgam diminished more quickly. Increasing mercury content in spherical amalgam increased cytotoxicity. Possible reactions for the diminution of cytotoxicity of amalgams with time are discussed...

journal_title：Journal of dental research

authors： Kawahara H,Nakamura M,Yamagami A,Nakanishi T

更新日期：1975-03-01 00:00:00

abstract：:The cartilaginous nasal septa of 28 albino rats were marked with pairs of wire implants. Measurements obtained from cephalometric radiographs taken at 30 and 60 days revealed that the implants invariably separatd and did so at a rate that was highly correlated with the growth of the rest of the snout. ...

journal_title：Journal of dental research

authors： Catala AE,Johnston LE Jr

更新日期：1980-08-01 00:00:00

abstract：:Sjögren's syndrome is a common autoimmune rheumatic disease. The most common symptoms of Sjögren's syndrome are extreme tiredness, along with dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia). Saliva plays an essential role in numerous functions of the mouth. Xerostomia can be caused by medications, chr...

journal_title：Journal of dental research

authors： Mathews SA,Kurien BT,Scofield RH

更新日期：2008-04-01 00:00:00

abstract：:Although systemic bone loss accompanying estrogen deficiency has been proposed as a risk factor for periodontal disease in post-menopausal women, the mechanisms involved remain unclear. The objective of this study was to elucidate the potential bone-sparing effect of estrogen (17beta-estradiol, E(2)) via modulation of...

journal_title：Journal of dental research

authors： Shu L,Guan SM,Fu SM,Guo T,Cao M,Ding Y

更新日期：2008-02-01 00:00:00

abstract：:The biocompatibility of two implant materials, vitallium and poly-methyl methacrylate (PMMA), was evaluated in an animal model in which bone formation and resorption are independent of each other. Neither material accelerated resorption, but formation was inhibited 12% by vitallium and 38% by PMMA. When three PMMA pre...

journal_title：Journal of dental research

authors： Garcia DA,Sullivan TM,O'Neill DM

更新日期：1981-01-01 00:00:00

abstract：:Fluorides are present in the environment. Excessive systemic exposure to fluorides can lead to disturbances of bone homeostasis (skeletal fluorosis) and enamel development (dental/enamel fluorosis). The severity of dental fluorosis is also dependent upon fluoride dose and the timing and duration of fluoride exposure. ...

journal_title：Journal of dental research

authors： Everett ET

更新日期：2011-05-01 00:00:00

abstract：:One-step incomplete excavation seals caries-affected dentin under a restoration and appears to be advantageous in the treatment of deep lesions. However, it is impossible to discriminate radiographically between intentionally left, arrested lesions and overlooked or active lesions. This diagnostic uncertainty decrease...

journal_title：Journal of dental research

authors： Schwendicke F,Meyer-Lueckel H,Schulz M,Dörfer CE,Paris S

更新日期：2014-06-01 00:00:00

abstract：:Experiments were performed to determine the role of the immune response in rat periodontal disease. Germ-free rats were fed defined antigen-free liquid diets or a diet containing ovalbumin(OVA) as a prototype antigen. The OVA-fed rats demonstrated increased gingival lymphocytes (mainly T at early times), OVA-sensitize...

journal_title：Journal of dental research

authors： Taubman MA,Yoshie H,Ebersole JL,Smith DJ,Olson CL

更新日期：1984-03-01 00:00:00

abstract：:The discovery of the phenomenon "osseointegration," or functional ankylosis, has led to the development of oral implants with high clinical performance. Consequently, the placement of titanium implants has changed the paradigms of restorative dentistry. Implants are used to prevent placing reconstructions anchored on ...

journal_title：Journal of dental research

authors： Lang NP

更新日期：2019-11-01 00:00:00

abstract：:Extracellular microcapsules have been demonstrated on cells of most serotypes of Streptococcus mutans by electron microscopy, using bacterial strains of the various serotypes and peroxidase labeled or unlabeled immune serum. A correlation was noted between the amount of capsular substance on the strains of S mutans ex...

journal_title：Journal of dental research

authors： Grenier EM,Gray RH,Loesche WJ,Eveland WC

更新日期：1977-02-01 00:00:00

abstract：:Since edentate subjects have a reduced masticatory function, it can be expected that the morphology of the cancellous bone of their mandibular condyles has changed according to the altered mechanical environment. In the present study, the morphology of cylindrical cancellous bone specimens of the mandibular condyles o...

journal_title：Journal of dental research

authors： Giesen EB,Ding M,Dalstra M,van Eijden TM

更新日期：2004-03-01 00:00:00

abstract：:Recent advances in molecular biology have facilitated analyses of the oral microbiome ("Who are they?"); however, its functions (e.g., metabolic activities) are poorly understood ("What are they doing?"). This review aims to summarize our current understanding of the metabolism of the oral microbiome. Saccharolytic ba...

journal_title：Journal of dental research

authors： Takahashi N

更新日期：2015-12-01 00:00:00

abstract：:The microstructures of (beta + gamma) silver-tin alloys are especially influenced by both homogenization temperature and subsequent heat treatment. When the alloy is cooled from homogenization temperatures above approximately 200 degrees C, lenticular regions of the ordered orthorhombic gamma phase precipitate from wi...

journal_title：Journal of dental research

authors： Abbott JR,Miller DR,Netherway DJ

更新日期：1985-05-01 00:00:00

abstract：:The pathophysiology of painful temporomandibular disorders is not fully understood, but evidence suggests that muscle pain modulates motor function in characteristic ways. This study tested the hypothesis that activation of nociceptive muscle afferent fibers would be linked to an increased excitability of the human ja...

journal_title：Journal of dental research

authors： Wang K,Arendt-Nielsen L,Svensson P

更新日期：2002-09-01 00:00:00

abstract：:The antimicrobial and cariostatic activities of the dihydrochloride and dihydrofluoride salts of alexidine (1,6-bis-[2-ethylhexylbiguanido]hexane) were compared to those of chlorhexidine acetate and sodium fluoride in rats implanted orally with Streptococcus mutans 6715 and fed a cariogenic diet. Experimental caries w...

journal_title：Journal of dental research

authors： Curtis SN,Dooley CL

更新日期：1979-04-01 00:00:00

abstract：:Mercury emitted from dental amalgam may select for increased numbers of antibiotic- or mercury-resistant commensal bacteria in patients and increase their risk for bacterial diseases that are resistant to common therapies. We hypothesized that the presence of dental amalgams would increase the level of mercury-, tetra...

journal_title：Journal of dental research

authors： Roberts MC,Leroux BG,Sampson J,Luis HS,Bernardo M,Leitão J

更新日期：2008-05-01 00:00:00

abstract：:The expression of antimicrobial peptides at epithelial surfaces such as skin, lung, and intestine is thought to provide protection against infection. Cathelicidin antimicrobial peptides are essential for the protection of skin against invasive bacterial infection. To determine if cathelicidins are also present in the ...

journal_title：Journal of dental research

authors： Murakami M,Ohtake T,Dorschner RA,Gallo RL

更新日期：2002-12-01 00:00:00

abstract：:Wall-to-wall (WTW) polymerization contraction of filled and unfilled chemically and photo-initiated resins was studied in relation to the WTW distance. In an experimental set-up, the resins were bonded to two opposing disks, and the axial (WTW) displacement resulting from the polymerization shrinkage was measured cont...

journal_title：Journal of dental research

authors： Feilzer AJ,De Gee AJ,Davidson CL

更新日期：1989-01-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is a potent inducer of angiogenesis, vascular permeability, and edema. Up-regulation of VEGF expression in the dental pulp may result in increased intra-pulpal pressure, and contribute to pain and irreversible tissue damage. Lipoteichoic acid (LTA) is an amphiphilic molecule f...

journal_title：Journal of dental research

authors： Telles PD,Hanks CT,Machado MA,Nör JE

更新日期：2003-06-01 00:00:00

abstract：:The aim of the present in vitro experiments was to determine whether the protection of enamel by topically applied fluoride against demineralization by bacterial acids would depend on the fluoride sensitivity of the bacteria. Glucose-agarose gel suspensions of fluoride-sensitive and fluoride-resistant mutans streptoco...

journal_title：Journal of dental research

authors： van Loveren C,Buijs JF,ten Cate JM

更新日期：1993-08-01 00:00:00

abstract：:In previous studies, human dental pulp stem cells (hDPSCs) were mainly isolated from adults. In this present study, we characterized hDPSCs isolated from an earlier developmental stage to evaluate the potential usage of these cells for tissue-regenerative therapy. hDPSCs isolated at the crown-completed stage showed a ...

journal_title：Journal of dental research

authors： Takeda T,Tezuka Y,Horiuchi M,Hosono K,Iida K,Hatakeyama D,Miyaki S,Kunisada T,Shibata T,Tezuka K

更新日期：2008-07-01 00:00:00

abstract：:Cyclic adenosine 3',5'-monophosphate (cAMP) concentrations and cellular distribution were studied in dental and periodontal tissues during tooth eruption in kittens. Although the mean levels of cAMP around developing teeth were similar in all the tissue samples, there were marked differences in cAMP stainability of ti...

journal_title：Journal of dental research

authors： Gustafson GT,Eckerdal O,Leever DL,Shanfeld JL,Montgomery P,Davidovitch Z

更新日期：1977-04-01 00:00:00

abstract：:A detailed understanding of the complexity of root canal systems is imperative to ensure successful root canal preparation. The aim of this study was to evaluate the potential and accuracy of a three-dimensional, non-destructive technique for detailing root canal geometry by means of high-resolution tomography. The an...

journal_title：Journal of dental research

authors： Peters OA,Laib A,Rüegsegger P,Barbakow F

更新日期：2000-06-01 00:00:00

abstract：:In this study, the differences in lesion remineralization and fluoride uptake after brushing with a 300 ppm F or a 1000 ppm F dentifrice (as NaF) were investigated. Twenty volunteers with partial dentures in their lower jaws were divided into two groups. Bovine enamel slabs with artificial lesions were mounted in the ...

journal_title：Journal of dental research

authors： De Kloet HJ,Exterkate RA,Rempt HE,Ten Cate JM

更新日期：1986-12-01 00:00:00

abstract：:In an attempt to determine the degree of co-activation present in selected cervical muscles during clenching, we instructed 12 male subjects to produce four brief maximum voluntary contraction (MVC) efforts (clenching) in a position of maximum intercuspation. Surface EMG activity was recorded bilaterally from the mass...

journal_title：Journal of dental research

authors： Clark GT,Browne PA,Nakano M,Yang Q

更新日期：1993-11-01 00:00:00

abstract：:Estrogen deficiency results in disruption of maxillary alveolar bone microarchitecture. Most of the actions of estrogen in long bones occur via estrogen receptor α (ERα). However, the function of ERα in the maxillary bone has not been defined. We aimed to investigate the role and underlying mechanisms of ERα in the ph...

journal_title：Journal of dental research

authors： Macari S,Ajay Sharma L,Wyatt A,Knowles P,Szawka RE,Garlet GP,Grattan DR,Dias GJ,Silva TA

更新日期：2016-06-01 00:00:00

abstract：:The Global Burden of Disease (GBD) 2010 Study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990. We u...

journal_title：Journal of dental research

authors： Marcenes W,Kassebaum NJ,Bernabé E,Flaxman A,Naghavi M,Lopez A,Murray CJ

更新日期：2013-07-01 00:00:00

abstract：:A numerical model of the mandible, its articulating surfaces, and the forces exerted by the primary masticatory muscles has been developed for the purpose of investigating loading of the temporomandibular joint. Evidence is presented which shows that the temporomandibular joint. Evidence is presented which shows that ...

journal_title：Journal of dental research

authors： Smith DM,McLachlan KR,McCall WD Jr

更新日期：1986-08-01 00:00:00