P2X4 is up-regulated in gingival fibroblasts after periodontal surgery.

abstract：:Thermal and mechanical hypersensitivity in the injured region is a common complication. Although it is well known clinically that thermal and mechanical sensitivity of the oral mucosa is different from that of the skin, the mechanisms underlying injured pain of the oral mucosa remain poorly understood. The transient r...

journal_title：Journal of dental research

authors： Urata K,Shinoda M,Honda K,Lee J,Maruno M,Ito R,Gionhaku N,Iwata K

更新日期：2015-03-01 00:00:00

abstract：:The effect of a topical fluoride regimen consisting of a four-minute pre-treatment with a saturated dicalcium phosphate dihydrate (DCPD) solution followed by a four-minute application of APF was compared with that of a four-minute application of APF alone with respect to the deposition of fluoride in enamel in an apat...

journal_title：Journal of dental research

authors： Crall JJ,Bjerga JM

更新日期：1986-03-01 00:00:00

abstract：:Periodontitis is a chronic infectious disease driven by dysbiosis, an imbalance between commensal bacteria and the host organism. Periodontitis is a leading cause of tooth loss in adults and occurs in about 50% of the US population. In addition to the clinical challenges associated with treating periodontitis, the pro...

journal_title：Journal of dental research

authors： Martins MD,Jiao Y,Larsson L,Almeida LO,Garaicoa-Pazmino C,Le JM,Squarize CH,Inohara N,Giannobile WV,Castilho RM

更新日期：2016-02-01 00:00:00

abstract：:Teeth undergo postnatal organogenesis relatively late in life and only complete full maturation a few years after the crown first erupts in the oral cavity. At this stage, development can be arrested if the tooth organ is damaged by either trauma or caries. Regenerative endodontic procedures (REPs) are a treatment alt...

journal_title：Journal of dental research

authors： Song JS,Takimoto K,Jeon M,Vadakekalam J,Ruparel NB,Diogenes A

更新日期：2017-06-01 00:00:00

abstract：:Symphyseal secondary cartilage is important for mandibular development, but the molecular mechanisms underlying its formation remain largely unknown. Here we asked whether Indian hedgehog (Ihh) regulates symphyseal cartilage development and growth. By embryonic days 16.5 to 18.5, Sox9-expressing chondrocytes formed wi...

journal_title：Journal of dental research

authors： Sugito H,Shibukawa Y,Kinumatsu T,Yasuda T,Nagayama M,Yamada S,Minugh-Purvis N,Pacifici M,Koyama E

更新日期：2011-05-01 00:00:00

abstract：:Continuous etching of aggressive all-in-one adhesives occurs in wet dentin tubules after polymerization of the adhesives. This study challenged the hypothesis that unpolymerized acidic monomers from an aggressive all-in-one self-etching adhesive continue to etch beyond dentin hybrid layers. Dentin surfaces bonded with...

journal_title：Journal of dental research

authors： Kim J,Mai S,Carrilho MR,Yiu CK,Pashley DH,Tay FR

更新日期：2010-05-01 00:00:00

abstract：:To determine the 'hard palate representing' area in the primary somatosensory cortex, we recorded somatosensory-evoked magnetic fields from the cortex in ten healthy volunteers, using magnetoencephalography. Following electrical stimulation of 3 sites on the hard palate (the first and third transverse palatine ridges,...

journal_title：Journal of dental research

authors： Bessho H,Shibukawa Y,Shintani M,Yajima Y,Suzuki T,Shibahara T

更新日期：2007-03-01 00:00:00

abstract：:Antigenic alterations to the dentin organic matrix may be detected by an immunohistochemical approach. We hypothesized that alterations in the antigenicity of type I collagen and proteoglycans occur in sclerotic dentin under caries lesions. Transverse sections were prepared from carious teeth in the sclerotic zone and...

journal_title：Journal of dental research

authors： Suppa P,Ruggeri A Jr,Tay FR,Prati C,Biasotto M,Falconi M,Pashley DH,Breschi L

更新日期：2006-02-01 00:00:00

abstract：:Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) nanocomplexes incorporated into sugar-free chewing gum have been shown to remineralize enamel subsurface lesions in situ. The aim of this study was to compare the ability of CPP-ACP, with that of other forms of calcium, to be retained in supragingival plaque ...

journal_title：Journal of dental research

authors： Reynolds EC,Cai F,Shen P,Walker GD

更新日期：2003-03-01 00:00:00

abstract：:Data from the actual private practices of two dentists were compared with respective data from the participation of the same two dentists in a laboratory model of private practice conducted in the University of North Carolina Dental Research Center. The findings show that a laboratory model can be established which ac...

journal_title：Journal of dental research

authors： Chadwick DG

更新日期：1975-05-01 00:00:00

abstract：:Dental porcelains that are designed to be fused to PFM (porcelain-fused-to-metal) alloys are formulated by their manufacturers to be closely matched in thermal expansion to these alloys. The high thermal expansion of the mineral leucite has been exploited to regulate porcelain expansion. Leucite, however, has been obs...

journal_title：Journal of dental research

authors： Mackert JR Jr,Twiggs SW,Williams AL

更新日期：2000-08-01 00:00:00

abstract：:Eugenol, in the 100 percent concentration in commercial use, was applied to a circumscribed area, 3 mm in diameter, of rat labial mucosa for 1 minute. Reaction periods of 15 minutes, 1, 2, 4 and 6 hours were then permitted. Using routine histological procedures for processing the experimental tissues, it was observed ...

journal_title：Journal of dental research

authors： Kozam G,Mantell GM

更新日期：1978-11-01 00:00:00

abstract：:Matrix metalloproteinase (MMP) inhibition has been shown to reduce adhesive bond degradation when applied as a pre-conditioner, adding to clinical steps in the placement of adhesives, but their incorporation within dental adhesives has not been fully explored. This study examined the effect of including 2 MMP inhibito...

journal_title：Journal of dental research

authors： Almahdy A,Koller G,Sauro S,Bartsch JW,Sherriff M,Watson TF,Banerjee A

更新日期：2012-06-01 00:00:00

abstract：:The aim of this study was to investigate the diffusion dynamics of 25% hydrogen peroxide (H2O2) through enamel-dentin layers and to correlate it with dentin's structural alterations. Micro-Raman Spectroscopy (MRS) and Fourier Transform Infrared Photoacoustic Spectroscopy (FTIR-PAS) were used to measure the spectra of ...

journal_title：Journal of dental research

authors： Ubaldini AL,Baesso ML,Medina Neto A,Sato F,Bento AC,Pascotto RC

更新日期：2013-07-01 00:00:00

abstract：:The effect of pH on the growth and proteolytic activity of the type strain and fresh isolates of Porphyromonas gingivalis and Bacteroides intermedius was investigated. B. intermedius strains grew with and without glucose at a pH as low as 5.0. These bacteria grew almost as well as Streptococcus mutans at pH 5.0 and be...

journal_title：Journal of dental research

authors： Takahashi N,Schachtele CF

更新日期：1990-06-01 00:00:00

abstract：:The synchronized cyrstal dissolution hypothesis previously proposed to explain the unusual dissolution behavior of human dental enamel and hydroxyapatite in partially saturated acidic media has been critically examined with dissolution-dialysis transport experiments. The findings are in accord with the hypothesis. A m...

journal_title：Journal of dental research

authors： Fawzi MB,Sonobe T,Higuchi WI,Hefferren JJ

更新日期：1977-04-01 00:00:00

abstract：:Gingiva from alloxan and streptozotocin-diabetic rats exhibited markedly enhanced collagenolytic activity in tissue culture. This effect was eliminated by puromycin or by repeated freeze-thawing of the tissue prior to incubation. Soluble extracts of the diabetic gingiva in situ were found to contain breakdown products...

journal_title：Journal of dental research

authors： Golub LM,Schneir M,Ramamurthy NS

更新日期：1978-03-01 00:00:00

abstract：:Glass-ionomer cements (GICs) are regarded as aqueous gels made up of polyalkenoic acid salts containing ion-leachable glass fillers. The consequence of water permeation across the GIC-dentin interface is unknown. This study used SEM, field-emission/environmental SEM (FE-ESEM), and TEM to examine the ultrastructure of ...

journal_title：Journal of dental research

authors： Yiu CK,Tay FR,King NM,Pashley DH,Sidhu SK,Neo JC,Toledano M,Wong SL

更新日期：2004-04-01 00:00:00

abstract：:Teas varying in fluoride and tannin concentration were evaluated in rats for anticariogenic activity. There was a direct correlation between fluoride in tea and the inhibition of sulcal caries in rats, whereas no relationship was observed between tannin and this type of lesion. Teas also had a significant effect on ca...

journal_title：Journal of dental research

authors： Rosen S,Elvin-Lewis M,Beck FM,Beck EX

更新日期：1984-05-01 00:00:00

abstract：:Autonomic and behavioral responses to seven dental procedures were studied in 21 pedodontic patients aged six to 12. When mean pulse rate, pulse amplitude, absolute skin conductance, and skin-conductance responses were compared over all subjects, the injection of the local anesthetic consistently elicited the greatest...

journal_title：Journal of dental research

authors： West GA,Reid KH,Bastawi AE

更新日期：1983-06-01 00:00:00

abstract：:Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...

journal_title：Journal of dental research

authors： Slade GD,Offenbacher S,Beck JD,Heiss G,Pankow JS

更新日期：2000-01-01 00:00:00

abstract：:Auto-degradation of collagen matrices occurs within hybrid layers created by contemporary dentin bonding systems, by the slow action of host-derived matrix metalloproteinases (MMPs). This study tested the null hypothesis that there are no differences in the activities of MMP-2 and -9 after treatment with different etc...

journal_title：Journal of dental research

authors： Mazzoni A,Scaffa P,Carrilho M,Tjäderhane L,Di Lenarda R,Polimeni A,Tezvergil-Mutluay A,Tay FR,Pashley DH,Breschi L

更新日期：2013-01-01 00:00:00

abstract：:The universally accepted concept of delay-loaded dental implants has recently been challenged. This study hypothesizes that early loading (decreased implant healing time) leads to increased bone formation and decreased crestal bone loss. We used 17 minipigs to study implants under a controlled load, with non-loaded im...

journal_title：Journal of dental research

authors： Ko CC,Douglas WH,DeLong R,Rohrer MD,Swift JQ,Hodges JS,An KN,Ritman EL

更新日期：2003-08-01 00:00:00

abstract：:Cementum is known to be growth-hormone (GH)-responsive, but to what extent is unclear. This study examines the effects of extremes of GH status on cementogenesis in three lines of genetically modified mice; GH excess (giant), GH antagonist excess (dwarf), and GH receptor-deleted (GHR-KO) (dwarf). Age-matched mandibula...

journal_title：Journal of dental research

authors： Smid JR,Rowland JE,Young WG,Daley TJ,Coschigano KT,Kopchick JJ,Waters MJ

更新日期：2004-01-01 00:00:00

abstract：:Physico-chemical investigations of enamel from deciduous teeth of a small number of children with and without pre-natal fluoride supplementation (PNF) exhibited the following differences between the PNF and non-PNF enamel, with the former showing: (a) more homogeneous and less extensive patterns of acid-etching; (b) d...

journal_title：Journal of dental research

authors： LeGeros RZ,Glenn FB,Lee DD,Glenn WD

更新日期：1985-03-01 00:00:00

abstract：:The uptake patterns of 90Sr in developing rat molar enamel were studied in vivo and in vitro. Autoradiographic methods were used that preclude loss or translocation of tracers associated with water-soluble compounds in the sections. In eight-day-old rats injected with the tracer, 90Sr uptake in the enamel was signific...

journal_title：Journal of dental research

authors： White BA,Deaton TG,Bawden JW

更新日期：1980-12-01 00:00:00

abstract：:1) A new adhesive opaque resin containing a reactive monomer, 4-methacryloxy-ethyl trimellitate anhydride (4-META), was prepared, and its application to thermosetting acrylic resin veneer crowns was studied. 2) The 4-META opaque resin was applied to a variety of nickel-chromium dental alloy specimens which had undergo...

journal_title：Journal of dental research

authors： Tanaka T,Nagata K,Takeyama M,Atsuta M,Nakabayashi N,Masuhara E

更新日期：1981-09-01 00:00:00

abstract：:The efficacy of a new remineralization system was determined in vivo by maintaining a low concentration of approximately 1 ppm fluoride for 48 hrs against a demineralized human tooth. Human subjects were selected who wore removable partial dentures containing two or more of the demineralized teeth with film system. Th...

journal_title：Journal of dental research

authors： Abrahams LJ,Yonese M,Higuchi WI,Fox JL,Charbeneau GT

更新日期：1980-03-01 00:00:00

abstract：:The effects of oral rinses on enamel fluoride uptake, caries, and plaque pH in rats were investigated by use of (1) an acidic calcium phosphate solution (CPS) saturated with dicalcium phosphate dihydrate (DCPD) and (2) a 1% fluoride solution. Osborne-Mendel rats, 19 days of age, were randomly assigned to one of four m...

journal_title：Journal of dental research

authors： Schreiber CT,Shern RJ,Chow LC,Kingman A

更新日期：1988-06-01 00:00:00

abstract：:Iodoacetate at 10(-3) M and 10(-4) M concentrations was found to strongly inhibit incorporation of both 14C-choline and 3H-inositol into phospholipids of calvaria from newborn rats; it had somewhat less effect on ethanolamine incorporation and almost no effect on serine incorporation. Similar though less dramatic resu...

journal_title：Journal of dental research

authors： Dirksen TR,Schuster GS,McKinney R,Bustos SE

更新日期：1975-09-01 00:00:00