The effect of eugenol on oral mucous membranes.

Abstract:

:Eugenol, in the 100 percent concentration in commercial use, was applied to a circumscribed area, 3 mm in diameter, of rat labial mucosa for 1 minute. Reaction periods of 15 minutes, 1, 2, 4 and 6 hours were then permitted. Using routine histological procedures for processing the experimental tissues, it was observed that eugenol caused denaturation of cytoplasmic proteins and loss of staining capacity of epithelium, loss of cell boundaries, swelling and cell necrosis. In addition, vesicle formation, edema in the corium, and striated muscle dissolution were observed.

journal_name

J Dent Res

authors

Kozam G,Mantell GM

doi

10.1177/00220345780570110901

subject

Has Abstract

pub_date

1978-11-01 00:00:00

pages

954-7

issue

11-12

eissn

0022-0345

issn

1544-0591

journal_volume

57

pub_type

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