Abstract:
:Continuous etching of aggressive all-in-one adhesives occurs in wet dentin tubules after polymerization of the adhesives. This study challenged the hypothesis that unpolymerized acidic monomers from an aggressive all-in-one self-etching adhesive continue to etch beyond dentin hybrid layers. Dentin surfaces bonded with Adper Prompt L-Pop were sectioned into 0.3-mm-thick slabs. Some of the slabs were stored in water (pH 6.8) or glycine buffer (pH 11.1) for six weeks and then examined by CLSM, SEM, and TEM. The rest were immersed in a biomimetic remineralizing medium for up to 4 months. Morphologic analysis indicated no difference in demineralization thickness between the two 6-week storage groups. However, increased permeability and loss of integrity occurred along the base of the hybrid layers in the glycine buffer group, but not in the water storage group. These findings were also confirmed by the results of biomimetic remineralization along the bases of those hybrid layers.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Kim J,Mai S,Carrilho MR,Yiu CK,Pashley DH,Tay FRdoi
10.1177/0022034510363665subject
Has Abstractpub_date
2010-05-01 00:00:00pages
482-7issue
5eissn
0022-0345issn
1544-0591pii
0022034510363665journal_volume
89pub_type
杂志文章,随机对照试验abstract::Streptococcus mutans produces 3 types of glucosyltransferase (GTF), whose cooperative action is considered to be essential for its cellular adherence to the tooth surface. However, the precise mechanisms for synthesizing adhesive glucans and the specific roles of each GTF in cellular adherence to smooth surfaces have ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345010800071401
更新日期:2001-07-01 00:00:00
abstract::In previous studies, light-cured glass-ionomer cements have been shown to evoke cytotoxic reactions. It was the purpose of this investigation (a) to determine the nature of the ingredients released into an aqueous medium from 2 light-cured glass-ionomer cements (GICs) and 3 compomers; (b) to evaluate the cytotoxicity ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345980770121001
更新日期:1998-12-01 00:00:00
abstract::Stem cells from exfoliated deciduous teeth (SHED) possess multipotent differentiation and immunomodulatory properties. They have been used for orofacial bone regeneration and autoimmune disease treatment. In this study, we show that acetylsalicylic acid (ASA) treatment is able to significantly improve SHED-mediated os...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514557672
更新日期:2015-01-01 00:00:00
abstract::An oral radiotelemetric technique was used to determine whether a range of efficient buffers had the capacity to control the levels of hydrogen ions within dental plaque in the presence of sucrose. It was found that the buffers failed to control both the intensity and duration of the acid produced. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345760550052601
更新日期:1976-09-01 00:00:00
abstract::It is shown that the creep behavior of a commercial dispersant-amalgam containing copper is improved by the addition of a manganese-containing alloy. This improvement is apparently obtained without any serious changes in corrosion resistance, provided that no more than 20% of the Mn alloy is added. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570090601
更新日期:1978-09-01 00:00:00
abstract::Bone resorption beneath a maxillary complete denture was simulated by the finite element method, assuming that a threshold of compressive strain exists in the alveolar bone above which the resorption occurred. The pattern of predicted resorption was observed when 100 N of force was applied to three positions occlusall...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680091601
更新日期:1989-09-01 00:00:00
abstract::Reporting the economic burden of oral diseases is important to evaluate the societal relevance of preventing and addressing oral diseases. In addition to treatment costs, there are indirect costs to consider, mainly in terms of productivity losses due to absenteeism from work. The purpose of the present study was to e...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515602879
更新日期:2015-10-01 00:00:00
abstract::Dental caries can be described as a dysbiosis of the oral microbial community, in which acidogenic, aciduric, and acid-adapted bacterial species promote a pathogenic environment, leading to demineralization. Alkali generation by oral microbes, specifically via arginine catabolic pathways, is an essential factor in mai...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034517707512
更新日期:2017-07-01 00:00:00
abstract::Genetic studies of early-onset periodontitis (EOP) are hampered by several factors. These include delayed onset of the trait, an upper age limit of expression of the disease, and lack of phenotypic information for edentulous family members. Segregation analyses of families with EOP support a major locus hypothesis but...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790031201
更新日期:2000-03-01 00:00:00
abstract::Previous studies have shown that fluoride affected the formation of apatite in spontaneous precipitations from unstable calcium phosphate solutions partly through its effect on the stability of such nonapatitic precursors as octacalcium phosphate, Ca8H2(PO4)6.5 H2O. The present study shows that fluoride had a comparab...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590021401
更新日期:1980-02-01 00:00:00
abstract::Primary cilia regulate several developmental processes and mediate hedgehog signaling. To study their roles in cranial base development, we created conditional mouse mutants deficient in Polaris, a critical primary cilium component, in cartilage. Mutant post-natal cranial bases were deformed, and their synchondrosis g...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509337775
更新日期:2009-06-01 00:00:00
abstract::Periostin is a mesenchymal cell marker predominantly expressed in collagen-rich fibrous connective tissues, including heart valves, tendons, perichondrium, periosteum, and periodontal ligament (PDL). Knockdown of periostin expression in mice results in early-onset periodontitis and failure of cardiac healing after acu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514543015
更新日期:2014-09-01 00:00:00
abstract::The effects of Escherichia coli endotoxin upon mouse L929 cell proliferation, DNA synthesis, protein synthesis, and proline incorporation were determined. It was found that a level of endotoxin which inhibited cell proliferation prompted a similar inhibition of DNA synthesis and overall cell protein synthesis. In cont...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580061301
更新日期:1979-06-01 00:00:00
abstract::Sintered samples of modifying porcelains of various colors and manufacturers were analyzed using reflectance spectrophotometry. Color designations are reported according to practices of the Commission Internationale de l'Eclairage (International Commission for Illumination), and color names were assigned based on a me...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345820610030801
更新日期:1982-03-01 00:00:00
abstract::The temporomandibular joint (TMJ) undergoes degenerative changes among patients who suffer from arthritis, and yet the pathogenesis of TMJ osteoarthritis and rheumatoid arthritis is poorly understood. We hypothesized that sustained inflammation in the TMJ induces structural abnormalities, and accordingly characterized...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512441946
更新日期:2012-05-01 00:00:00
abstract::Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these enzymes regulate the tiss...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034508330861
更新日期:2009-03-01 00:00:00
abstract::Cyclic adenosine 3',5'-monophosphate (cAMP) concentrations and cellular distribution were studied in dental and periodontal tissues during tooth eruption in kittens. Although the mean levels of cAMP around developing teeth were similar in all the tissue samples, there were marked differences in cAMP stainability of ti...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560040801
更新日期:1977-04-01 00:00:00
abstract::The feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. Forty rhesus monkeys, Macaca mulatta, were used. Cariogenic streptococci, S mutans, were implanted into all the monkeys' mouths. There was no pathological effect resulting from immunization...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560123001
更新日期:1977-12-01 00:00:00
abstract::The work described considers the effects on calcified tissues of those concentrations of fluoride which are not overtly cyto-toxic, i.e., in the general region of up to 1-2 mumol/L. Plasma fluoride concentrations or those of the cellular environment are considered rather than dietary levels. The effect of fluoride ion...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/00220345900690S134
更新日期:1990-02-01 00:00:00
abstract::Extracellular vesicles (EVs), several tens to hundreds of nanometers in size, are vesicles secreted by cells for intercellular communication. EVs released from mesenchymal stem cells (MSC-EVs) have the potential to treat multiple diseases. This study aimed to determine the effects of MSC-EVs on bisphosphonate-related ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034520906793
更新日期:2020-05-01 00:00:00
abstract::Samples of a base mental alloy were cast and welded together using a conventional welding procedure. The joints were loaded and placed either in a corrosive environment or in air for varying time periods. The tensile and shear strength of the joints was unaffected by the corrosive environment, and the joints, despite ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600021101
更新日期:1981-02-01 00:00:00
abstract::The aim of the present study was to describe the patterns of dental fluorosis in the primary and the permanent dentition of children born and reared in two different fluoridated areas, one in which powdered milk suspended in tap water was commonly used (Narssaq, Greenland: 1.1 ppm fluoride in the water) and one in whi...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670050501
更新日期:1988-05-01 00:00:00
abstract::The human temporalis and masseter muscles are not activated homogeneously during static bite force tasks. In this study, we studied the possible existence of regional differences in these muscles under dynamic conditions. Electromyographic (EMG) activity was recorded by means of bipolar fine-wire electrodes. Six elect...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740061201
更新日期:1995-06-01 00:00:00
abstract::Dental epithelial progenitor cells differentiate into various cell types during development of tooth germs. To study this mechanism, we produced immortalized dental epithelial progenitor cells derived from the cervical-loop epithelium of a rat lower incisor. The expression patterns of cytokeratin 14, nerve growth fact...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408300209
更新日期:2004-02-01 00:00:00
abstract::Matrix metalloproteinase (MMP) inhibition has been shown to reduce adhesive bond degradation when applied as a pre-conditioner, adding to clinical steps in the placement of adhesives, but their incorporation within dental adhesives has not been fully explored. This study examined the effect of including 2 MMP inhibito...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034512446339
更新日期:2012-06-01 00:00:00
abstract::The reaction of the microvasculature in the periodontal ligament to mechanical pressure is considered a very important phenomenon with respect to the biological background to orthodontic tooth movement. For clarification of the microvascular reaction to mechanical pressure, an experimental model that incorporated a ha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345920710060701
更新日期:1992-06-01 00:00:00
abstract::A number of studies have been made investigating the properties of dental prosthodontic soft polymer materials. In such materials, which are used as short-term denture soft liners, the polymer component is complexed with one or more plasticizers. This lowers the glass transition temperature, Tg, of the polymer by allo...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345910700050201
更新日期:1991-05-01 00:00:00
abstract::Although a large body of scientific literature shows that background color and luminance affect color perception, previous measurements of tooth color difference thresholds have not taken the effects of viewing context into account. The present study tested the hypothesis that differences in skin/gingival color influe...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034510376772
更新日期:2010-11-01 00:00:00
abstract::Before the 1960s, tooth-specific caries risk was reported to be highest at 2 to 4 years after eruption. We studied the tooth-specific caries risk in three contemporary age cohorts in Finland. All together, 4072 boys and girls were followed annually from age 6 to age 18+ years in three age cohorts born in the 1960s, 19...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract::A sintered hydroxyapatite (HAP) ceramic for use in wear studies was prepared from a commercial tricalcium phosphate. The sintered HAP had physical properties close to those of human enamel. The coefficient of friction and wear of the sintered HAP ceramic as characterized by tangential force, track width, and surface f...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345780570070401
更新日期:1978-07-01 00:00:00