Effect of metabolic inhibitors on bone lipid synthesis from radioactive bases.

Abstract:

:Iodoacetate at 10(-3) M and 10(-4) M concentrations was found to strongly inhibit incorporation of both 14C-choline and 3H-inositol into phospholipids of calvaria from newborn rats; it had somewhat less effect on ethanolamine incorporation and almost no effect on serine incorporation. Similar though less dramatic results were observed with cyanide or dinitrophenol at similar concentrations.

journal_name

J Dent Res

authors

Dirksen TR,Schuster GS,McKinney R,Bustos SE

doi

10.1177/00220345750540050101

keywords:

subject

Has Abstract

pub_date

1975-09-01 00:00:00

pages

1009-14

issue

5

eissn

0022-0345

issn

1544-0591

journal_volume

54

pub_type

杂志文章
  • Establishment of an improved implantation technique for hamster mucous membrane irritation testing.

    abstract::Biological evaluation procedures for the acceptance of new dental materials include testing for mucous membrane irritation and inflammation, with the hamster cheek pouch used as a model system. Previous reports have indicated both a low 14-day implant retention rate and poor differentiation between positive and negati...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345860650111801

    authors: Roy M,Wishe HI

    更新日期:1986-11-01 00:00:00

  • Build-up and repair of light-cured composites: bond strength.

    abstract::Interfacial bond strengths of light-activated composites were measured as a function of age using a transverse strength test. Bond strength between layers decreased with the age of the initial layer and reflected the setting curves of the composites. The highly-filled composites exhibited the greatest bond strengths. ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345840630101501

    authors: Boyer DB,Chan KC,Reinhardt JW

    更新日期:1984-10-01 00:00:00

  • Extracellular iodophilic polysaccharide synthesized by Neisseria in human dental plaque.

    abstract::Dental plaque collected from the label aspect of the anterior dentition of children harbored Neisseria that synthesized an extracellular iodophilic polysaccharide (EIP) from sucrose. Gas chromatograms of fully-acetylated EIP derivatives indicated that glucose (97%) and galactose (3%) were the only monosaccharide const...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345820610050101

    authors: Ruby JD,Shirey RE,Gerencser VF,Stelzig DA

    更新日期:1982-05-01 00:00:00

  • Fluoride's effects on the formation of teeth and bones, and the influence of genetics.

    abstract::Fluorides are present in the environment. Excessive systemic exposure to fluorides can lead to disturbances of bone homeostasis (skeletal fluorosis) and enamel development (dental/enamel fluorosis). The severity of dental fluorosis is also dependent upon fluoride dose and the timing and duration of fluoride exposure. ...

    journal_title:Journal of dental research

    pub_type: 杂志文章,评审

    doi:10.1177/0022034510384626

    authors: Everett ET

    更新日期:2011-05-01 00:00:00

  • Microscopic study of smooth silver-plated retention pins in amalgam.

    abstract::A silver-plating technique was developed in an effort to produce good mechanical bonding characteristics between stainless steel pins and amalgam. Metallographic microscope and scanning electron microscope (SEM) studies were made to assess the presence, or otherwise, of such a bond between (a) the silver layer plating...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345800590020301

    authors: Galindo Y,McLachlan K,Kasloff Z

    更新日期:1980-02-01 00:00:00

  • Dental pulp cells for induced pluripotent stem cell banking.

    abstract::Defined sets of transcriptional factors can reprogram human somatic cells to induced pluripotent stem (iPS) cells. However, many types of human cells are not easily accessible to minimally invasive procedures. Here we evaluated dental pulp cells (DPCs) as an optimal source of iPS cells, since they are easily obtained ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034510366846

    authors: Tamaoki N,Takahashi K,Tanaka T,Ichisaka T,Aoki H,Takeda-Kawaguchi T,Iida K,Kunisada T,Shibata T,Yamanaka S,Tezuka K

    更新日期:2010-08-01 00:00:00

  • Elevated oral and systemic levels of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in periodontitis.

    abstract::The Triggering Receptor Expressed on Myeloid cells 1 (TREM-1) is a cell-surface receptor of the immunoglobulin superfamily, involved in the propagation of the inflammatory response to bacterial challenge. Soluble (s)TREM-1 is released from the cell surface during the course of infection and is a useful inflammatory bi...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034512470691

    authors: Bostanci N,Oztürk VÖ,Emingil G,Belibasakis GN

    更新日期:2013-02-01 00:00:00

  • Axonal Degeneration in Dental Pulp Precedes Human Primary Teeth Exfoliation.

    abstract::The dental pulp in human primary teeth is densely innervated by a plethora of nerve endings at the coronal pulp-dentin interface. This study analyzed how the physiological root resorption (PRR) process affects dental pulp innervation before exfoliation of primary teeth. Forty-four primary canine teeth, classified into...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034515593055

    authors: Suzuki K,Lovera M,Schmachtenberg O,Couve E

    更新日期:2015-10-01 00:00:00

  • The formation and remineralization of artificial white spot lesions: a constant composition approach.

    abstract::Artificial white spot lesions have been prepared on bovine enamel surfaces by the controlled addition of lactate buffer containing methylhydroxydiphosphonate ions. The rates of remineralization have been measured using a constant composition method in solutions of calcium phosphate of low supersaturation. Deposition o...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345840630061001

    authors: de Rooij JF,Nancollas GH

    更新日期:1984-06-01 00:00:00

  • Adhesive 4-META/MMA-TBB opaque resin with poly(methyl methacrylate)-coated titanium dioxide.

    abstract::An adhesive opaque resin for veneering on cast metal was developed with 4-methacryloxyethyl trimellitate anhydride and poly (methyl methacrylate)-coated titanium dioxide prepared by aqueous phase polymerization. The opaque resin was a modified 4-META/MMA-TBB resin. The powder consisted of 20% of the encapsulated mater...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345880670010501

    authors: Matsumura H,Nakabayashi N

    更新日期:1988-01-01 00:00:00

  • Wavelength-independent microradiography: a method for non-destructive quantification of enamel and dentin mineral concentrations using polychromatic x-rays.

    abstract::Wavelength-independent Microradiography (WIM), described in this paper, used polychromatic, high-energy (less than or equal to 60 kV) x-rays for determination of mineral concentrations in tooth material non-destructively. This was done with the aid of a reference step-wedge made of 94% aluminum, 6% zinc. The mass atte...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345900690081501

    authors: Herkströter FM,Ten Bosch JJ

    更新日期:1990-08-01 00:00:00

  • Natural defenses against Candida colonization breakdown in the oral cavities of the elderly.

    abstract::Candida colonization of the oral cavity increases in the elderly. A major predisposing condition is denture use, which also increases in the elderly. To test whether the increase in colonization is age-related in a fashion independent of denture use, we analyzed the frequency (incidence) of carriage, the intensity of ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345990780040601

    authors: Lockhart SR,Joly S,Vargas K,Swails-Wenger J,Enger L,Soll DR

    更新日期:1999-04-01 00:00:00

  • Impact of Age on Disease Progression and Microenvironment in Oral Cancer.

    abstract::Despite the recognized link between aging and cancer, most preclinical studies in experimental tumor models are conducted with 6- to 8-wk-old rodents. The goal of the present study was to examine the impact of age on tumor incidence, growth, and microenvironmental characteristics in mouse models of head and neck squam...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034518775736

    authors: Vincent-Chong VK,DeJong H,Rich LJ,Patti A,Merzianu M,Hershberger PA,Seshadri M

    更新日期:2018-10-01 00:00:00

  • The surface free energy of oral streptococci after being coated with saliva and its relation to adhesion in the mouth.

    abstract::Contact angle measurements on layers of bacteria were used to determine the bacterial surface free energy (gamma b) of a variety of oral streptococcal strains, both without and after being coated with human whole saliva. At least four isolates of each species, either freshly isolated or laboratory strains, were used. ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345850640100501

    authors: Weerkamp AH,van der Mei HC,Busscher HJ

    更新日期:1985-10-01 00:00:00

  • Chondroitin sulfate in palatal wound healing.

    abstract::Chondroitin sulfate is up-regulated in granulation tissue during wound healing. To investigate the role of chondroitin sulfate in the wound-healing process after surgical repair of cleft palate, we isolated and cultured rabbit palatal fibroblasts. Treatment with chondroitin-6-sulfate resulted in a dose-dependent incre...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910408301111

    authors: Zou XH,Foong WC,Cao T,Bay BH,Ouyang HW,Yip GW

    更新日期:2004-11-01 00:00:00

  • Inhibition of apoptosis in early tooth development alters tooth shape and size.

    abstract::Apoptosis plays important roles in various stages of organogenesis. In this study, we hypothesized that apoptosis would play an important role in tooth morphogenesis. We examined the role of apoptosis in early tooth development by using a caspase inhibitor, z-VAD-fmk, concomitant with in vitro organ culture and tooth ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910608500610

    authors: Kim JY,Cha YG,Cho SW,Kim EJ,Lee MJ,Lee JM,Cai J,Ohshima H,Jung HS

    更新日期:2006-06-01 00:00:00

  • Dental fluorosis in an area of Kenya with 2 ppm fluoride in the drinking water.

    abstract::We examined 102 children born and reared in an area of rural Kenya with 2 ppm fluoride in the drinking water for dental fluorosis, using the index developed by Thylstrup and Fejerskov (1978). The prevalence of dental fluorosis was 100%, 92% of all teeth exhibited a TFI score of 4 or higher, and 50% of the children had...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345860650050501

    authors: Manji F,Baelum V,Fejerskov O

    更新日期:1986-05-01 00:00:00

  • A review of potential new diagnostic modalities for caries lesions.

    abstract::This paper aims to present a simple overview of potential new diagnostic methods for dental caries. There are several novel methods of caries detection (with potential application to diagnosis) which have been proposed in the last few years, in addition to those that are gaining some commercial exposure and clinical a...

    journal_title:Journal of dental research

    pub_type: 杂志文章,评审

    doi:10.1177/154405910408301s18

    authors: Hall A,Girkin JM

    更新日期:2004-01-01 00:00:00

  • The growth hormone receptor gene is associated with mandibular height in a Chinese population.

    abstract::Genetic influences are important in the determination of mandibular morphology, and growth hormone receptor (GHR) is believed to have an important influence on the growth of craniofacial bone. In this study, we used quantitative trait locus methods to evaluate the relationship between craniofacial morphology and singl...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910508401116

    authors: Zhou J,Lu Y,Gao XH,Chen YC,Lu JJ,Bai YX,Shen Y,Wang BK

    更新日期:2005-11-01 00:00:00

  • Setting reactions and compressive strengths of calcium phosphate cements.

    abstract::Setting reactions and compressive strengths of a self-hardening calcium phosphate cement (CPC) were investigated. The CPC consists of tetracalcium phosphate (TTCP) and anhydrous dicalcium phosphate (DCPA). The cement specimens were prepared by mixing 0.7 g of the powder (TTCP 72.9 wt% + DCPA 27.1 wt%) with 0.175 mL of...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345900690121201

    authors: Fukase Y,Eanes ED,Takagi S,Chow LC,Brown WE

    更新日期:1990-12-01 00:00:00

  • Finite element stress analysis of a class I amalgam restoration subjected to setting and thermal expansion.

    abstract::Stress analyses are presented for a second mandibular premolar with a class 1 amalgam restoration. The effects of amalgam setting and thermal expansions are examined. An axisymmetric representation of the structure is used and the analyses are carried out by the finite element method. Lined and unlined restorations ar...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345780570051101

    authors: Wright KW,Yettram AL

    更新日期:1978-05-01 00:00:00

  • The Aymara of western Bolivia: III. Occlusion, pathology, and characteristics of the dentition.

    abstract::With the objective of contributing to the understanding of factors influencing the characteristics of dentition, dental observations from 429 children and adult highland people of western Bolivia are described. Various age, sex, ethnic, and village differences are observed in malocclusion, dental caries, periodontal d...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345780570030901

    authors: Palomino H

    更新日期:1978-03-01 00:00:00

  • Genetics of human taste perception.

    abstract::Genetic approaches are rapidly yielding new information about our sense of taste. This information comes from both molecular studies of genes encoding taste receptors and other taste-signaling components, and from studies of inherited variation in taste abilities. Our understanding of bitter taste has advanced by comb...

    journal_title:Journal of dental research

    pub_type: 杂志文章,评审

    doi:10.1177/154405910408300603

    authors: Kim UK,Breslin PA,Reed D,Drayna D

    更新日期:2004-06-01 00:00:00

  • Preliminary observations on the effect of mantle field radiotherapy on salivary flow rates in patients with Hodgkin's disease.

    abstract::Changes in stimulated and non-stimulated whole saliva flow rates were measured in 11 Hodgkin's disease patients who received therapeutic doses of radiation to a mantle field at the M. D. Anderson Hospital in Houston, Texas. Salivary flow rates were examined before, during, and after radiotherapy. Mean flow rate reduct...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345880670021801

    authors: Bucher JA,Fleming TJ,Fuller LM,Keene HJ

    更新日期:1988-02-01 00:00:00

  • Functional adaptability of jaw-muscle spindles after bite-raising.

    abstract::In a previous experiment, we found that masseter muscle spindles show functional plasticity after 5 to 15 days under increased occlusal vertical dimension (iOVD). In the present study, we hypothesized that spindle function would eventually recover if longer observation periods were allowed. Therefore, in this study we...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910608500914

    authors: Yabushita T,Zeredo JL,Fujita K,Toda K,Soma K

    更新日期:2006-09-01 00:00:00

  • Trigeminal nociceptors express TLR-4 and CD14: a mechanism for pain due to infection.

    abstract::Although certain bacterial species appear to be risk factors for pain due to odontogenic infections, comparatively little is known about the potential mechanisms mediating this effect. In this study, we tested the hypothesis that trigeminal nociceptive neurons express the TLR4 or CD14 receptors, thus enabling sensory ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910608500108

    authors: Wadachi R,Hargreaves KM

    更新日期:2006-01-01 00:00:00

  • Oxidative stress-induced DNA damage in the synovial cells of the temporomandibular joint in the rat.

    abstract::Synovial hyperplasia is a feature of degenerative temporomandibular joint (TMJ) disease. However, the mechanism by which hyperplasia progresses in the TMJ is unknown. Based on the hypothesis that the oxidative stress generated by mechanical loading causes degenerative changes in the TMJ synovium, we investigated the g...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/154405910408300807

    authors: Yamaza T,Masuda KF,Atsuta I,Nishijima K,Kido MA,Tanaka T

    更新日期:2004-08-01 00:00:00

  • The effect of eugenol on oral mucous membranes.

    abstract::Eugenol, in the 100 percent concentration in commercial use, was applied to a circumscribed area, 3 mm in diameter, of rat labial mucosa for 1 minute. Reaction periods of 15 minutes, 1, 2, 4 and 6 hours were then permitted. Using routine histological procedures for processing the experimental tissues, it was observed ...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/00220345780570110901

    authors: Kozam G,Mantell GM

    更新日期:1978-11-01 00:00:00

  • Expression of resolvin D1 biosynthetic pathways in salivary epithelium.

    abstract::Resolvins are potent anti-inflammatory mediators derived from ω-3 fatty acids. Results from our previous studies indicated that resolvin D1 (RvD1) blocks pro-inflammatory responses in salivary glands. Furthermore, RvD1 enhances salivary epithelial integrity, demonstrating its potential use for the restoration of saliv...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034513519108

    authors: Leigh NJ,Nelson JW,Mellas RE,Aguirre A,Baker OJ

    更新日期:2014-03-01 00:00:00

  • Associations among Periodontitis, Calcified Carotid Artery Atheromas, and Risk of Myocardial Infarction.

    abstract::Cardiovascular disease is a common cause of morbidity and premature mortality. Cardiovascular disease can be prevented when risk factors are identified early. Calcified carotid artery atheromas (CCAAs), detected in panoramic radiographs, and periodontitis have both been associated with increased risk of cardiovascular...

    journal_title:Journal of dental research

    pub_type: 杂志文章

    doi:10.1177/0022034519885362

    authors: Gustafsson N,Ahlqvist J,Näslund U,Buhlin K,Gustafsson A,Kjellström B,Klinge B,Rydén L,Levring Jäghagen E

    更新日期:2020-01-01 00:00:00