Abstract：
:Focusing public insurance programs on interceptive orthodontics (IO) may increase access for low-income children. This report presents outcomes from a randomized clinical trial (RCT) comparing IO with comprehensive orthodontics (CO) in Medicaid patients. One hundred seventy pre-adolescents with Medicaid-eligible malocclusions were randomized to IO (n = 86) followed by observation (OBS) or OBS followed by CO (n = 84). One hundred thirty-four completed the trial. Models at pre-treatment (baseline) and following ≤ 2 years of intervention and 2 years of OBS (48 mos) were scored by calibrated examiners using the Peer Assessment Rating (PAR) and Index of Complexity, Outcome and Need (ICON). Overall outcomes and clinically meaningful categorical ICON data on need/acceptability, complexity, and improvement were compared. At baseline, groups were balanced by age, gender, ethnicity, and PAR/ICON scores. Most were minorities. Most (77%) were rated as difficult-to-very difficult. Scores improved significantly for both groups, but CO more than IO (PAR, 18.6 [95%CI 15.1, 22.1] vs.10.1 [95%CI 6.7, 13.4]; ICON, 44.8 [95% CI 39.7, 49.9] vs. 35.2 [95%CI 29.7, 40.6], respectively). On average, IO is effective at reducing malocclusions in Medicaid patients, but less than CO. (ClinicalTrials.gov number CT00067379).
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
King GJ,Spiekerman CF,Greenlee GM,Huang GJdoi
10.1177/0022034512448663subject
Has Abstractpub_date
2012-07-01 00:00:00pages
59S-64Sissue
7 Suppleissn
0022-0345issn
1544-0591pii
91/7_suppl/S59journal_volume
91pub_type
杂志文章,随机对照试验abstract：:The adsorption isotherms of benzoic acid on synthetic hydroxyapatite (containing about 1.5 monolayers of physisorbed water) were studied from ethanol, dimethylsulfoxide, p-dioxane, methylene chloride, and benzene to discern the role of solvent in the process. The adsorption is reversible from the first three solvents ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650051601
更新日期：1986-05-01 00:00:00
abstract：:The etiology and pathogenesis of craniofacial birth defects are multifactorial and include both genetic and environmental factors. Despite the identification of numerous genes associated with congenital craniofacial anomalies, our understanding of their etiology remains incomplete, and many affected individuals have a...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520969109
更新日期：2020-11-06 00:00:00
abstract：:Spontaneously occurring bacteriophage-resistant mutants of Actinomyces viscosus were isolated. The mutants exhibited altered coaggregation patterns with streptococci. From analysis of the data, it appears that a cell surface structure on A. viscosus may function both as a phage receptor and as a binding site for co-ag...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345830620111801
更新日期：1983-11-01 00:00:00
abstract：:The universally accepted concept of delay-loaded dental implants has recently been challenged. This study hypothesizes that early loading (decreased implant healing time) leads to increased bone formation and decreased crestal bone loss. We used 17 minipigs to study implants under a controlled load, with non-loaded im...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910308200803
更新日期：2003-08-01 00:00:00
abstract：:Recent studies have shown that the extent of hydrolysis by plaque of the trypsin substrate, N-benzoyl-DL-arginine-2-naphthylamide (BANA), correlates with the numbers and proportions of spirochetes in subgingival plaque samples, and appears to be an indicator of clinical disease. In this study, BANA hydrolysis by subgi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670121201
更新日期：1988-12-01 00:00:00
abstract：:A full understanding of the key regulators controlling periodontal development and homeostasis is necessary for the design of improved periodontal regenerative therapies. Small leucine-rich proteoglycans (SLRPs) are extracellular matrix molecules suggested to regulate collagen organization and cell signaling. Mice wit...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034514541126
更新日期：2014-08-01 00:00:00
abstract：:Lipopolysaccharide (LPS) has been shown to be a prominent pathogenic factor in inflammatory bone loss. However, knowledge of the mechanisms involved is limited. The role of the SDF-1/CXCR4 (Stromal-derived factor-1 and its unique chemokine receptor) axis in LPS-induced bone loss has not been studied. The aim of this s...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510379019
更新日期：2011-02-01 00:00:00
abstract：:Degradation of dentin matrix components within caries dentin has been correlated with the activity of host-derived proteases, such as matrix metalloproteases (MMPs) and cysteine cathepsins (CTs). Since this relationship has not been fully established, we hypothesized that the abundance of MMPs and CTs in caries-affect...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513516979
更新日期：2014-03-01 00:00:00
abstract：:Dental caries is a microbially mediated disease that can result in significant tooth structure degradation. Although the preponderance of lesions is treated by surgical intervention, various strategies have been developed for its noninvasive management. Here, we use a novel approach for noninvasive treatment based on ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515619370
更新日期：2016-03-01 00:00:00
abstract：:Candida albicans is an opportunistic fungal organism frequently detected in the oral cavity of children with severe early childhood caries (S-ECC). Previous studies suggested the cariogenic potential of C. albicans, in vitro and in vivo, and further demonstrated its synergistic interactions with Streptococcus mutans. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034518790941
更新日期：2018-12-01 00:00:00
abstract：:Limited cure depth is a drawback of light-activated composites. We hypothesize that curing light transmission and cure depth are influenced by monomer reactivity and filler/resin refractive index mismatch. Light transmission throughout cure was recorded for composites based on strontium (refractive index 1.51) or bari...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910808700115
更新日期：2008-01-01 00:00:00
abstract：:During the setting of a resin composite cement (RCC) used as an adhesive between a resin-bonded bridge and tooth structure, the adhesion may be disrupted by the development of shrinkage stress. The aim of this study was to investigate the influence of the shrinkage stress of three different RCCs on their adhesive and ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710021101
更新日期：1992-02-01 00:00:00
abstract：:Mercury emitted from dental amalgam may select for increased numbers of antibiotic- or mercury-resistant commensal bacteria in patients and increase their risk for bacterial diseases that are resistant to common therapies. We hypothesized that the presence of dental amalgams would increase the level of mercury-, tetra...
journal_title：Journal of dental research
pub_type： 杂志文章,随机对照试验
doi：10.1177/154405910808700502
更新日期：2008-05-01 00:00:00
abstract：:The main purpose of this paper is to review the various methods used for evaluation of fluoride retention in saliva, plaque, and enamel following application of topical anti-caries treatments such as F dentifrices and F mouthwashes. Such methods monitor delivery of fluoride to the site of action, the mouth, and so can...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/002203459207100S29
更新日期：1992-04-01 00:00:00
abstract：:T6 antigen is a highly specific marker for human Langerhans cells (LC). Previous studies have demonstrated that Interleukin-1 (IL-1) and an IL-1 inhibitor (ILS) modulate LC T6 expression (T6E) in explant culture. The present study examined the in vitro modulation of T6E by two molecules: epidermal-cell-derived thymocy...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345870660031201
更新日期：1987-03-01 00:00:00
abstract：:The goal of this study was to assess the ability of a scintillation camera method to detect areas of active bone loss due to periodontitis. Technetium 99m methylene diphosphonate was used as the bone-seeking radiopharmaceutical. Bone-seeking radiopharmaceutical uptake (BSRU) was imaged and quantified in alveolar bone ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345910700010801
更新日期：1991-01-01 00:00:00
abstract：:Three dental amalgams were investigated to determine if their abrasion resistance was significantly affected by different packing pressures. Abrasive wear tests were performed on a machine designed to test materials under conditions similar to masticatory function. The results show that the abrasion resistance of the ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560060901
更新日期：1977-06-01 00:00:00
abstract：:It is generally accepted that glass ionomers inhibit secondary caries in vivo, and data from in vitro studies support this effect. The aim of this review was a systematic assessment, from the literature, of clinical evidence for the ability of glass-ionomer restoratives to inhibit secondary caries at the restoration m...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/00220345990780020101
更新日期：1999-02-01 00:00:00
abstract：:Using a hydraulic bellows system mounted on a maxillary partial denture, continuous force-displacement data were taken in an edentulous area in the maxillary bicuspid-molar region on ten adults. Both loading and unloading force-displacement curves showed three segments. Two visco-elastic properties - hysteresis and re...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630101901
更新日期：1984-10-01 00:00:00
abstract：:Indigenous populations around the world experience a disproportionate burden in terms of oral diseases and conditions. These inequalities are likely due to a complex web of social determinants that includes poverty, historical consequences of colonialism, social exclusion, government policies of assimilation, cultural...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034518763605
更新日期：2018-07-01 00:00:00
abstract：:The presence and kinetics of bone-resorbing activity in periapical lesions were studied with a rat model system. Lesions were found to expand most rapidly between induction on day 0 and day 15 ("active phase"), with enlargement occurring at a slower rate thereafter (days 20 and 30, "chronic phase"), as assessed by mea...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345910700100901
更新日期：1991-10-01 00:00:00
abstract：:Although it has been shown that patients are more satisfied with prostheses supported by implants than with conventional dentures, there have been few direct comparisons of the various designs of implant-supported prostheses. This within-subject crossover clinical trial was designed to compare two forms of removable p...
journal_title：Journal of dental research
pub_type： 临床试验,杂志文章
doi：10.1177/00220345970760100901
更新日期：1997-10-01 00:00:00
abstract：:Oral bacteria, including Streptococcus mutans and Streptococcus salivarius, contribute to tooth decay and plaque formation; therefore, it is essential to develop strategies to prevent dental caries and plaque formation. We recently showed that organo-selenium compounds covalently attached to different biomaterials inh...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513482141
更新日期：2013-05-01 00:00:00
abstract：:Rotational freedom of the implant-abutment connection influences its screw joint stability; for optimization, influential factors need to be evaluated based on a previously developed closed formula. The underlying hypothesis is that the manufacturing tolerances, geometric pattern, and dimensions of the index do not in...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034509341243
更新日期：2009-08-01 00:00:00
abstract：:The human mandibular condyle has a parasagittal plate-like trabecular structure. We tested the hypothesis that this structure reflects the mechanical loading of the condyle. We developed a finite element model of the condyle to analyze the strains occurring during static compressive loading. The principal strains in t...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910208101010
更新日期：2002-10-01 00:00:00
abstract：:The tissue-implant interfaces of functional and non-functional endosseous dental implants were compared histologically for up to one year post-operatively. Nonmineralized connective tissue zones (a "fibrous capsule") existed in all functional interfaces. Direct, or nearly direct, bone apposition to implants occurred i...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345790580100201
更新日期：1979-10-01 00:00:00
abstract：:The effect of inflammation on the distribution of chondroitin sulfate and dermatan sulfate proteoglycans was assessed after normal and inflamed human gingivae were stained with monoclonal antibodies against these extracellular matrix macromolecules. The tissues were obtained following periodontal surgery and reacted w...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710090801
更新日期：1992-09-01 00:00:00
abstract：:Significant associations between atherosclerosis and both Porphyromonas gingivalis, a major periodontopathogen, and the respiratory pathogen, Chlamydia pneumoniae, have been shown. Many individuals with evidence of atherosclerosis demonstrate seropositivity to these pathogens. The aim of the present study was to exami...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910708600105
更新日期：2007-01-01 00:00:00
abstract：:The treatment of periodontitis/peri-implantitis involves the reduction/eradication of periopathogens. After therapy, beneficial and pathogenic species recolonize the subgingival area. The dynamics of recolonization and especially the role of the supragingival environment in this process are still not well-understood. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910508400409
更新日期：2005-04-01 00:00:00
abstract：:Resin composites currently available are not suitable for use as large stress-bearing posterior restorations involving cusps due to their tendencies toward excessive fracture and wear. The glass fillers in composites provide only limited reinforcement because of the brittleness and low strength of glass. The aim of th...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345990780021101
更新日期：1999-02-01 00:00:00
