Abstract：
:The kinetics of subsurface demineralization of tooth sections has been studied in real-time by scanning microradiography (SMR). Demineralization was carried out: (1) with a large volume of solution buffered to pH = 4 to maintain a constant composition; and (2) in a small constant volume (approximately 3 mL), buffered initially at pH = 4, so that the degree of saturation at the tooth surface increased as the tooth dissolved. At constant composition, the change in lesion depth, Y, with time, T, followed a linear relation, Y = a + bT, for T > 44 +/- 5 h. Before this time, the relation could be approximated by a linear one with different a and b constants. At constant volume, Y = q(1-e-r(T + s)) for all T, where q, r and s are constants. Similar relations, with different constants, were found for the mineral loss per unit area of lesion exposed to acid. These results showed that the process of demineralization under the rather severe conditions used was essentially a surface-controlled process. The change of slope at approximately 44 h and the presence of the constant s in the exponential function were attributed to a change in kinetics after formation of the surface layer.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Gao XJ,Elliott JC,Anderson Pdoi
10.1177/00220345930720051401subject
Has Abstractpub_date
1993-05-01 00:00:00pages
923-30issue
5eissn
0022-0345issn
1544-0591journal_volume
72pub_type
杂志文章abstract：:Autoimmune responses to heat-shock protein 60 (HSP60) contribute to the progression of atherosclerosis, whereas immunization with HSP60 may induce atheroprotective responses. We assessed the capacity of an atheroprotective vaccine that targeted a recombinant HSP60 from Porphyromonas gingivalis (rGroEL) to induce a pro...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034514523784
更新日期：2014-04-01 00:00:00
abstract：:The adsorption isotherms of benzoic acid on synthetic hydroxyapatite (containing about 1.5 monolayers of physisorbed water) were studied from ethanol, dimethylsulfoxide, p-dioxane, methylene chloride, and benzene to discern the role of solvent in the process. The adsorption is reversible from the first three solvents ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650051601
更新日期：1986-05-01 00:00:00
abstract：:Greater fluoride concentrations were obtained in enamel treated with phosphate/fluoride solutions than in that treated with TiF4 at similar pH's (1.0) and F concentrations (0.6M F and 1.6M F). However, fluoride solution without added phosphate at pH 1.0 and 1.6M F concentration produced lower fluoride concentrations i...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345790580021001
更新日期：1979-02-01 00:00:00
abstract：:The relative contribution of the matrix of dentin to the physical properties of dentin is unknown but thought to be small. The objective of this study was to test the hypothesis that the demineralized matrix of dentin contributes little to the strength of dentin by measuring and comparing the ultimate tensile strength...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345940730061201
更新日期：1994-06-01 00:00:00
abstract：:The aim of the present in vitro experiments was to determine whether the protection of enamel by topically applied fluoride against demineralization by bacterial acids would depend on the fluoride sensitivity of the bacteria. Glucose-agarose gel suspensions of fluoride-sensitive and fluoride-resistant mutans streptoco...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720080401
更新日期：1993-08-01 00:00:00
abstract：:The pathomechanics of degenerative joint disease of the temporomandibular joint (TMJ) may involve fatigue produced by mechanical work on the articulating tissues. This study tested the hypotheses that mechanical work in the TMJ (i) varies with the type of mandibular activity, and (ii) is evenly distributed over TMJ su...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910608501106
更新日期：2006-11-01 00:00:00
abstract：:Composite resin restorations in cavities are generally associated with the development of a contraction gap during the first minutes after insertion. Enamel-Bond-Concise composite restoration were placed on both approximal sides of extracted pre-molars. The cervical walls of all cavities extended beyond the enamel-cem...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630051501
更新日期：1984-05-01 00:00:00
abstract：:We have previously reported the clinical and radiographic findings of a trial in dogs of a new dental implant system after a functional period of eight months. The present report consists of the corresponding qualitative and quantitative histological data. The implant system was fabricated from Ti-6A1-4V and employed ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345880670090801
更新日期：1988-09-01 00:00:00
abstract：:Tempering of dental porcelain by forced convective cooling in air has been shown previously to inhibit the sizes of cracks induced in porcelain surfaces. However, the depth of compressive stress that is produced by tempering of feldspathic porcelain has not been determined. It can be assumed that the potential of temp...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345910700020701
更新日期：1991-02-01 00:00:00
abstract：:Frequent consumption of cariogenic foods and bacterial infection are risk factors for early childhood caries (ECC). This study hypothesized that a short diet survey focused on frequency of foods, categorized by putative cariogenicity, would differentiate severe ECC (S-ECC) from caries-free children. Children's diets w...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510376543
更新日期：2010-11-01 00:00:00
abstract：:Pain and discomfort are common problems for patients undergoing orthodontic treatment. We have demonstrated that cortical excitation propagation in the somatosensory and insular cortices (IC) induced by electrical stimulation of the periodontal ligament (PDL) is facilitated 1 d after experimental tooth movement (ETM)....
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520962465
更新日期：2020-10-08 00:00:00
abstract：:Chronic periodontitis is a multi-factorial disease involving anaerobic bacteria and the generation of an inflammatory response, including the production of metalloproteinases, pro-inflammatory cytokines, and eicosanoids. Hypochlorous acid (HOCl) and taurine-N-monochloramine (TauCl) are the end-products of the neutroph...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/154405910408301101
更新日期：2004-11-01 00:00:00
abstract：:Chemotherapeutics are presently considered for use in caries-preventive programs. The laboratory and in vivo testing of these agents, to some extent, parallels the methodology developed for the evaluation of fluoride products. However, fluoride is primarily effective by interfering with the de- and remineralization ba...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/00220345940730031601
更新日期：1994-03-01 00:00:00
abstract：:Heads of Swiss-Webster mouse fetuses of four ages spanning days 12-13 of gestation, were partially dissected by removing the brain (B), tongue (T) and mandible (M) alone or in combination (BT, BM, BTM). Preparations were suspended in a gassed, circulating culture system such that palatal closure must take place agains...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345780570024401
更新日期：1978-02-01 00:00:00
abstract：:Mutations and common polymorphisms in interferon regulatory factor 6 ( IRF6) are associated with both syndromic and nonsyndromic forms of cleft lip/palate (CLP). To date, much of the focus on this transcription factor has been on identifying its direct targets and the gene regulatory network in which it operates. Nota...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034517723615
更新日期：2017-10-01 00:00:00
abstract：:Evidence that dental status affects diet is equivocal. The hypothesis of this study was that diet was affected by dental status. The objective was to assess the relationship between numbers of teeth and diet and nutritional status in US adult civilians without prostheses. We examined 6985 NHANES (1988-1994) participan...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910708601206
更新日期：2007-12-01 00:00:00
abstract：:When measured once, psychological stress predicts development of painful temporomandibular disorder (TMD). However, a single measurement fails to characterize the dynamic nature of stress over time. Moreover, effects of stress on pain likely vary according to biological susceptibility. We hypothesized that temporal es...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515595043
更新日期：2015-09-01 00:00:00
abstract：:The authors tested the hypothesis that obstructive sleep apnea (OSA) signs/symptoms are associated with the occurrence of temporomandibular disorder (TMD), using the OPPERA prospective cohort study of adults aged 18 to 44 years at enrollment (n = 2,604) and the OPPERA case-control study of chronic TMD (n = 1,716). In ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513488140
更新日期：2013-07-01 00:00:00
abstract：:It was recently reported that human periapical cysts (hPCys), a commonly occurring odontogenic cystic lesion of inflammatory origin, contain mesenchymal stem cells (MSCs) with the capacity for self-renewal and multilineage differentiation. In this study, periapical inflammatory cysts were compared with dental pulp to ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515570316
更新日期：2015-06-01 00:00:00
abstract：:At the present time, peri-implantitis has become a global burden that occurs with a frequency from 1% to 47% at implant level. Therefore, we aimed herein at assessing the impact of peri-implant maintenance therapy (PIMT) on the prevention of peri-implant diseases. Electronic and manual literature searches were conduct...
journal_title：Journal of dental research
pub_type： 杂志文章,meta分析,评审
doi：10.1177/0022034515622432
更新日期：2016-04-01 00:00:00
abstract：:Although it is known that diabetes impairs oral wound healing, relatively little is known about the cellular parameters affected, particularly in connective tissue. This study investigated the hypothesis that diabetes impairs connective tissue formation in healing gingiva, and that impaired healing is associated with ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510362960
更新日期：2010-06-01 00:00:00
abstract：:Three single-composition, high-copper amalgams were analyzed for the composition of their before- and after-reaction phases. The method used was electron probe microanalysis. The results may be summarized as follows: All alloys consist essentially of Ag3Sn (gamma), Cu3Sn (epsilon), and, in some cases, Ag4Sn (beta). Wh...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345840630062301
更新日期：1984-06-01 00:00:00
abstract：:Silver cations generated by passing low intensity direct current through pure silver electrodes were found to be sufficiently antibacterial to cause sterilization of samples of infected dentin. The optimal procedure involved a 5 microA current applied for 20 minutes with the anode then left in contact with the sample....
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345780570091901
更新日期：1978-09-01 00:00:00
abstract：:Modulation of the phosphoinositide signal transduction pathway by arachidonic acid (AA) in collagenase-dispersed rat submandibular acinar cells was investigated. The muscarinic agonist, carbachol, stimulated PIP2 hydrolysis and the generation of IP3 to five-fold the control levels. This response was inhibited by 75% o...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345920710080101
更新日期：1992-08-01 00:00:00
abstract：:Hemifacial microsomia (HFM) is a congenital disorder marked by facial asymmetry. Whether facial asymmetry accounts for asymmetrical dental development is unknown. There are few data on dental development relative to mandibular development or severity of HFM, or on development over time. We hypothesized that when mandi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034510378425
更新日期：2010-12-01 00:00:00
abstract：:IL-18 is a pro-inflammatory cytokine that is important in the regulation of T-cells and is elevated in inflammatory disorders such as periodontal disease. Vasoactive intestinal peptide (VIP) modulates immune responses to the periodontal pathogen Porphyromonas gingivalis (Pg). Our objective was to investigate the effec...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910708600915
更新日期：2007-09-01 00:00:00
abstract：:The firing pattern of the motor units (MUs) in jaw-elevator muscles was studied within a wide range of isometric contraction levels by means of changes in the frequency and broadness of the primary peak in the low-frequency (5-40 Hz) power spectral density function of the surface EMG. EMG was recorded from both masset...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345940730051501
更新日期：1994-05-01 00:00:00
abstract：:In two separate experiments, none of the 14 subunits examined consistently ranked dentifrices similarly to the ranking obtained when the individual rat was used as the experimental unit. Arbitrarily dividing the rat into subunits and then comparing results among these subunits may lead to false conclusions since the r...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345760550032901
更新日期：1976-05-01 00:00:00
abstract：:We have isolated a specific cell wall antigen of high molecular weight which appears to be unique to virulent strains of A viscosus and A naeslundii. The antigen is composed of two parts: a polysaccharide moiety containing 6-DOT as the major sugar and determinant of serologic specificity, and a small peptide bearing s...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/002203457605500111011
更新日期：1976-01-01 00:00:00
abstract：:Due, in part, to the unique structure of the tooth, dental pain is initiated via distinct mechanisms. Here we review recent advances in our understanding of inflammatory tooth pain and discuss 3 hypotheses proposed to explain dentinal hypersensitivity: The first hypothesis, supported by functional expression of temper...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034513501877
更新日期：2013-11-01 00:00:00
