Abstract：
:The following five outlines are the results to date of the Workshop held in Rockville, Maryland, in January, 1990. The topics considered in these outlines are: (1) validation of immunological and/or nucleic acid identification probes, (2) cross-calibration of methods and/or laboratories for multi-laboratory cooperative studies, (3) choosing methods for identifying or describing microbial populations appropriate to the scientific question asked, (4) microbial ecology methods (e.g., population dynamics) for the oral cavity studies, and (5) epidemiological methods (e.g., incidence, risk factor analysis) for oral microbial studies. Each topic was considered by two independent groups of participants and later rationalized into one. These outlines are meant to be working outlines for evolution of a set of guidelines to advise on designing studies with microbial incidence and/or population components. We are publishing this preliminary version to elicit comment and criticism from people who did not attend the Workshop. (Attendance at the Workshop was necessarily limited by both space and funds). Some of the topic outlines have been condensed to save Journal space. The full document is available on request. The next stage will be an open forum to gather and discuss further amplification of the "Guidelines", planned for April 17, 1991, Acapulco, Mexico, in conjunction with the IADR/AADR Meeting. Written comments and requests for further information should be sent to the Workshop organizer (MIK) at the above address.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Krichevsky MIdoi
10.1177/00220345910700031401subject
Has Abstractpub_date
1991-03-01 00:00:00pages
226-32issue
3eissn
0022-0345issn
1544-0591journal_volume
70pub_type
指南,杂志文章abstract：:The etiology and pathogenesis of craniofacial birth defects are multifactorial and include both genetic and environmental factors. Despite the identification of numerous genes associated with congenital craniofacial anomalies, our understanding of their etiology remains incomplete, and many affected individuals have a...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034520969109
更新日期：2020-11-06 00:00:00
abstract：:The cariostatic benefit from water fluoridation is indisputable, but the knowledge of possible adverse effects on bone and fracture risk due to fluoride exposure is ambiguous. The association between long-term (chronic) drinking water fluoride exposure and hip fracture (ICD-7-9: '820' and ICD-10: 'S72.0-S72.2') was as...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513506443
更新日期：2013-11-01 00:00:00
abstract：:The spatial relationship of the mandibular condyle to the temporal component of the TMJ is determined quantitatively from lateral tomograms using a new method of measuring specific areas of the joint space. Condyle position along the posteroanterior axis of the joint is expressed as a ratio of the posterior joint spac...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345810600010701
更新日期：1981-01-01 00:00:00
abstract：:The aim of this study was to test the potential of liposomes as drug carriers to the ulcerated oral mucosa. Radioactive triamcinolone acetonide palmitate (3H-TRMAp) was encapsulated in large multilamellar lipid vesicles and served as the test lotion. 3H-TRMAp in solution served as control. Forty-six hamsters were divi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650090501
更新日期：1986-09-01 00:00:00
abstract：:microRNAs could be mechanosensitive and emerge as critical posttranscriptional regulators in the bone-remodeling process. During orthodontic tooth movement (OTM), the application of mechanical force induces alveolar bone remodeling, but whether microRNAs respond to orthodontic force and contribute to OTM is unknown. m...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034516657043
更新日期：2016-11-01 00:00:00
abstract：:Dentinal pain in connection with mechanical stimulation i.e. probing, chiseling and initial drilling may be due to removal of fluid from the dentinal tubules. Loss of fluid due to "normal" evaporation from exposed dentin may produce an outward flow in the dentinal tubules rapid enough to cause pain and within a few mi...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345780570012001
更新日期：1978-01-01 00:00:00
abstract：:Our observations confirm the previously reported observation that multinucleated cells develop within a two-week period in cat bone-marrow cultures. Calcitonin induces cytoplasmic contraction in these multinucleated cells, which indicates that they resemble osteoclasts. After seven days of culture, cat bone-marrow cul...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345860650070201
更新日期：1986-07-01 00:00:00
abstract：:Cell therapies utilizing mesenchymal stem cells (MSCs) could overcome limitations of traditional treatments for reconstructing craniofacial tissues. This large-scale study explored a standardized methodology for the isolation and clinical-scale expansion of alveolar bone marrow-derived MSCs (aBMSCs). We harvested 103 ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034513510530
更新日期：2014-01-01 00:00:00
abstract：:Medication-related osteonecrosis of the jaw (MRONJ), although initially believed to be exclusively associated with bisphosphonates, has been implicated in recent reports with additional drugs, especially the bone antiresorptive denosumab. The pathophysiology has not been fully elucidated, and no causal association bet...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034515572021
更新日期：2015-04-01 00:00:00
abstract：:In the past decade, medical genetic research has generated multiple discoveries, many of which were obtained via genome-wide association studies (GWASs). A major GWAS finding is that the majority of risk variants for complex traits map to noncoding regions. This has resulted in a paradigm shift in terms of the interpr...
journal_title：Journal of dental research
pub_type： 杂志文章,评审
doi：10.1177/0022034517720403
更新日期：2017-10-01 00:00:00
abstract：:Debonding rates of 164 resin-bonded prostheses (RBP) placed from 1974 to 1985 were examined at recall. The yearly debond rates were calculated, the cumulative probability of failure was determined for the debonded RBPs, and Weibull distribution parameters were determined. For perforated prostheses, there was a high in...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720081401
更新日期：1993-08-01 00:00:00
abstract：:Schoolchildren residing in a fluoride-deficient area were provided either a sodium fluoride (0.1% F) or a nonfluoride dentifrice for home use. About half the children provided each type of dentifrice were also given an initial prophylaxis. Combining the data with regard to the type of dentifrice indicated that the sod...
journal_title：Journal of dental research
pub_type： 临床试验,杂志文章
doi：10.1177/00220345750540013601
更新日期：1975-01-01 00:00:00
abstract：:Previous studies showed that residual compressive stresses induced by thermal tempering retarded the growth of surface cracks in bilayered porcelain disks. The objectives of the present study were: (1) to determine whether thermal tempering by air blasting reduces the length of cracks induced by microhardness indentat...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345960750020301
更新日期：1996-02-01 00:00:00
abstract：:Caries of the permanent first molars of 5-year-old children was found to be associated with caries of their diciduous teeth. The sample consisted of 220 children whose permanent first molars had erupted. They were selected out of 965 children who were a representative sample of children attending compulsory kindergart...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345760550062001
更新日期：1976-11-01 00:00:00
abstract：:A frameshift mutation recently identified within the paired domain of the transcription factor, PAX9, has been linked to a unique form of oligodontia in a single, multigenerational family (Stockton et al., 2000). We now describe the phenotypic and segregation analyses of this remarkable kindred, the initial approach t...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345000790070701
更新日期：2000-07-01 00:00:00
abstract：:Seven oral doses of demethylchlortetracycline were administered to monkeys that received serial injections of lead acetate to intravitally stain calcification sites. Bone growth was greatly inhibited, whereas dentin apposition was spared from the cumulative toxicity of demethylchlortetracycline. Cessation of bone grow...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：:Short-chain carboxylic acids (e.g., lactic acid, propionic acid, butyric acid) are metabolic by-products of bacterial metabolism which can accumulate in the gingival crevice. It is of no small consequence, therefore, that 1- to 5-mM concentrations of these acids exhibit significant biological activity, including the a...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345970760010801
更新日期：1997-01-01 00:00:00
abstract：:Conservative techniques for improving the appearance of discolored teeth have become popular in the past decade. These include: in-office bleaching with 30% hydrogen peroxide, which is applied on etched enamel with a gauze pad and then exposed to a bleaching light; home bleaching with a mild form of peroxide, such as ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345930720011001
更新日期：1993-01-01 00:00:00
abstract：:Wear striations experimentally produced on initially unworn teeth were examined at high magnification using a scanning electron microscope. Certain characteristics of individual wear striations on these teeth indicate the direction of motion that produced them. Other striations on worn teeth of American Indians and th...
journal_title：Journal of dental research
pub_type： 历史文章,杂志文章
doi：10.1177/00220345790580011401
更新日期：1979-01-01 00:00:00
abstract：:Cementum is known to be growth-hormone (GH)-responsive, but to what extent is unclear. This study examines the effects of extremes of GH status on cementogenesis in three lines of genetically modified mice; GH excess (giant), GH antagonist excess (dwarf), and GH receptor-deleted (GHR-KO) (dwarf). Age-matched mandibula...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910408300107
更新日期：2004-01-01 00:00:00
abstract：:Cellular hypoxia may be a useful indication of tissue distress in the dental pulp that could be used to investigate the early stages of pulpal responses. Tritiated misonidazole (3H-MISO) is a marker which preferentially labels cells with decreased oxygen tension (hypoxia). The experiments reported here were carried ou...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345960750100801
更新日期：1996-10-01 00:00:00
abstract：:Bone remodeling is a complex process regulated by several mediators. Recent work has revealed that cytokines and growth factors have significant effects on bone cell metabolism. However, little information is available concerning the production of cytokines during orthodontic tooth movement in human subjects, and ther...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345960750010801
更新日期：1996-01-01 00:00:00
abstract：:It was recently reported that human periapical cysts (hPCys), a commonly occurring odontogenic cystic lesion of inflammatory origin, contain mesenchymal stem cells (MSCs) with the capacity for self-renewal and multilineage differentiation. In this study, periapical inflammatory cysts were compared with dental pulp to ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034515570316
更新日期：2015-06-01 00:00:00
abstract：:The dentition in zebrafish is extremely and richly vascularized, but the function of the vasculature, in view of the continuous replacement of the teeth, remains elusive. Through application of SU5416, a vascular endothelial growth factor receptor inhibitor, we studied the role of the blood vessels in the dentition of...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/0022034514557156
更新日期：2015-01-01 00:00:00
abstract：:Better understanding of dental caries and other oral conditions has guided new strategies to prevent disease and manage its consequences at individual and public health levels. This article discusses advances in prevention and minimal intervention dentistry over the last century by focusing on some milestones within s...
journal_title：Journal of dental research
pub_type： 历史文章,杂志文章
doi：10.1177/0022034519837252
更新日期：2019-06-01 00:00:00
abstract：:A quantitative microprobe analysis was conducted on three commercial amalgams to determine the nature of the phases present. The presence of tin in the Ag-Hg phase (gamma1) was confirmed and Cu-3Sn was found in the original alloy particles. In the dispersant amalgam studied, little Sn-Hg phase (gamma-2) was found and ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：:The mechanism of formation of nodular material on the surface of a Pd-Ag-based alloy for porcelain during pre-porcelainization heat treatment was investigated using scanning electron microscopy, x-ray diffraction, quantitative metallography, and Auger electron spectroscopy. The nodules were found to form by a Nabarro-...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345830620121201
更新日期：1983-12-01 00:00:00
abstract：:Numerous studies have demonstrated that many older adults have problems chewing, pain, difficulties in eating, and problems in social relationships because of oral disorders. However, it is not clear if these functional and psychosocial outcomes affect broader psychological well-being and life satisfaction. Consequent...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345000790041301
更新日期：2000-04-01 00:00:00
abstract：:An analysis of the relationship between creep and microstructural characteristics of several gamma2-containing amalgams showed the grain size of the Ag-Hg phase (gamma1) to be a predominant factor influencing creep. When gamma1 grain size is increased, creep is reduced. ...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/00220345770560121401
更新日期：1977-12-01 00:00:00
abstract：:Periodontitis is characterized by periodontal tissue destruction. Since interleukin-17 (IL-17) has been reported to up-regulate IL-1beta and tumor necrosis factor-alpha (TNF-alpha), it was hypothesized that it is increased in periodontitis and up-regulates these cytokines and tissue-destructive matrix metalloproteinas...
journal_title：Journal of dental research
pub_type： 杂志文章
doi：10.1177/154405910708600409
更新日期：2007-04-01 00:00:00
