Abstract:
:We report the identification of bovine miRNAs by cloning small RNAs from adipose tissue and the mammary gland. Fifty-nine distinct miRNAs were identified, five of them were not homologous to known mammalian miRNAs, and many of them had 3' and/or 5' end variants. Ribonuclease protection assays indicated that miR-23a and miR-24, whose genes are closely located on the same chromosome, were co-expressed in different tissues. The assays also suggested a role for several miRNAs in the mammary gland and a role for miR-133, a previously known skeletal and cardiac muscle-specific miRNA, in the rumen, an organ unique to the ruminant.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Gu Z,Eleswarapu S,Jiang Hdoi
10.1016/j.febslet.2007.01.081subject
Has Abstractpub_date
2007-03-06 00:00:00pages
981-8issue
5eissn
0014-5793issn
1873-3468pii
S0014-5793(07)00131-7journal_volume
581pub_type
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