Abstract:
:The impact of cytomegalovirus (CMV) infection of the genital tract during pregnancy on adverse pregnancy outcomes is not understood fully. A real-time PCR assay was used to determine vaginal shedding of CMV in 993 healthy pregnant Japanese women and the results were compared with the outcome of pregnancy. CMV DNA was detected in 76 (7.7%) of the women. The outcome of pregnancy could be determined finally in 848 women, of whom 60 (7.1%) were CMV positive. The carriers of CMV had an increased miscarriage rate (RR 6.96, 95% CI 2.04-23.84, P < 0.01). These findings suggest that latent genital tract CMV infection predisposes to adverse pregnancy outcomes.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Tanaka K,Yamada H,Minami M,Kataoka S,Numazaki K,Minakami H,Tsutsumi Hdoi
10.1002/jmv.20619subject
Has Abstractpub_date
2006-06-01 00:00:00pages
757-9issue
6eissn
0146-6615issn
1096-9071journal_volume
78pub_type
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