Neutralization epitope diversity of coxsackievirus B4 isolates detected by monoclonal antibodies.

abstract：:One hundred fifty-five chronic hepatitis C patients were assigned at random to receive natural lymphoblastoid interferon (IFN)alpha-n1, s.c., for 13 months in one of three treatment regimens: initial daily induction with 10 million units (MU) followed (group 1, n = 50) or not (group 2, n = 52) by 1 month of rest and t...

journal_title：Journal of medical virology

authors： Diago M,Suárez D,García-Villarreal L,Castro A,Domínguez A,Pardo M,del Olmo JA,Pérez-Hernández F,Aguilar J,Quiroga JA,Carreño V

更新日期：2001-08-01 00:00:00

abstract：:Poliovirus (PV) is a member of the species Enterovirus C (EV-C), which may cause irreversible paralysis and death. So, for the purpose of analyzing the evolution of PV2 to help in eradicating PVs globally, a recombination analysis was performed to verify all viral genomes of EV-C, and we found 13 putative recombinatio...

journal_title：Journal of medical virology

authors： Qian Y,Pu X,Yu Y,Yu X,Kong L,Liu L,Wang H,Shen H

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA was found in the intestines and feces, but its clinical significance is not completely clear. We aim to characterize the longitudinal test results of SARS-CoV-2 RNA in anal swabs and to explore the association with disease severity. METHODS:We...

journal_title：Journal of medical virology

authors： Lin W,Xie Z,Li Y,Li L,Wen C,Cao Y,Chen X,Ou X,Hu F,Li F,Tang X,Cai W,Li L

更新日期：2021-02-01 00:00:00

abstract：:In vitro incubation of human cytomegalovirus (Towne strain) with 8 U/ml human recombinant myeloperoxidase plus sodium chloride and glucose nearly abolished viral infectivity. To assay the effect on intracellular infection, cell toxicity of the enzymes was first studied. Even the high dose of 16 U/ml of recombinant mye...

journal_title：Journal of medical virology

authors： El Messaoudi K,Verheyden AM,Thiry L,Fourez S,Tasiaux N,Bollen A,Moguilevsky N

更新日期：2002-02-01 00:00:00

abstract：:Herpes simplex virus can be quantitatively recovered from vaginal tampons suspended in tissue culture medium and stored over a wide range of temperatures. Because herpes simplex virus is stable for several days with refrigeration or after freezing, this method of culture of cervicovaginal virus lends itself to epidemi...

journal_title：Journal of medical virology

authors： Myers MG,Ekwo EE,Pitts AK

更新日期：1979-01-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) and human immunodeficiency virus type 1 (HIV-1) may interact during transplacental transmission of HIV-1. The placental syncytiotrophoblast layer serves as the first line of defense of the fetus against viruses. Patterns of replication of HHV-6 variant A (HHV-6A) and HIV-1 were analyzed in ...

journal_title：Journal of medical virology

authors： Csoma E,Bácsi A,Liu X,Szabó J,Ebbesen P,Beck Z,Kónya J,Andirkó I,Nagy E,Tóth FD

更新日期：2002-05-01 00:00:00

abstract：:A polymerase chain reaction-restriction (PCR-restriction) endonuclease assay was developed to allow rapid analysis of influenza A H3N2 viruses circulating in England during 1995-1996. Restriction endonuclease digestion with two enzymes of amplicons derived from PCR of the HA1 portion of the influenza haemagglutinin (H...

journal_title：Journal of medical virology

authors： Ellis JS,Sadler CJ,Laidler P,de Andrade HR,Zambon MC

更新日期：1997-03-01 00:00:00

abstract：:Polymorphisms upstream interleukin (IL)-28B gene and serum levels of interferon gamma inducible protein-10 (IP-10) are associated with spontaneous and treatment-induced hepatitis C virus (HCV) clearance. Patients with seronegative occult HCV infection are anti-HCV and serum HCV-RNA negative but have viral RNA in liver...

journal_title：Journal of medical virology

authors： Bartolomé J,Castillo I,Quiroga JA,Carreño V

更新日期：2016-02-01 00:00:00

abstract：:The purpose of this study was to investigate determinants of endemic hepatitis C virus (HCV) infection within communities in Taiwan. A two-phase study, including a seroprevalence survey and a prevalent case-control study at the first phase, which has been published previously, and a follow-up seroconversion determinat...

journal_title：Journal of medical virology

authors： Sun CA,Chen HC,Lu SN,Chen CJ,Lu CF,You SL,Lin SH

更新日期：2001-09-01 00:00:00

abstract：:Recent studies have identified epithelial cell populations in human livers that are similar to the "oval cells" and "transitional cells" seen in rat livers during the early stages of chemical carcinogenesis. It has been suggested that these cells might be precursors of hepatocytes and theoretically could be involved i...

journal_title：Journal of medical virology

authors： Hsia CC,Thorgeirsson SS,Tabor E

更新日期：1994-07-01 00:00:00

abstract：:The hepatitis C virus (HCV) infects a substantial proportion of patients infected with human immunodeficiency virus (HIV). Patients infected with both HCV and HIV respond poorly to anti-HCV treatment with pegylated interferon alpha and ribavirin. But few data are available on the influence of ribavirin and interferon ...

journal_title：Journal of medical virology

authors： Nicot F,Legrand-Abravanel F,Lafont T,Dubois M,Sauné K,Pasquier C,Chatelut E,Izopet J

更新日期：2008-09-01 00:00:00

abstract：:One hundred twenty strains of adenovirus types 1, 2, 5, and 6 (subgenus C), isolated at various times and places, were tested by neutralization and hemagglutination inhibition with two antisera of each type. Except for one type 5 strain they reacted largely type-specifically in both tests and neither qualitative nor q...

journal_title：Journal of medical virology

authors： Kaier B,Wigand R

更新日期：1986-03-01 00:00:00

abstract：:Serum specimens from 1,109 individuals at different ages in Beijing, China, were collected between April 1996 and March 1997 and tested for IgG antibodies against human caliciviruses using enzyme immune assays (EIAs). Baculovirus-expressed recombinant Norwalk virus (rNV) and Mexican virus (rMxV) capsid proteins were u...

journal_title：Journal of medical virology

authors： Jing Y,Qian Y,Huo Y,Wang LP,Jiang X

更新日期：2000-01-01 00:00:00

abstract：:Hepatitis D virus (HDV) infection can cause severe acute and chronic liver disease in patients infected with hepatitis B virus (HBV). Despite the significant decline in the global HDV infection, it remains a major health concern in some countries. This study aimed to investigate the prevalence and clinical features of...

journal_title：Journal of medical virology

authors： Kim HS,Kim SJ,Park HW,Shin WG,Kim KH,Lee JH,Kim HY,Jang MK

更新日期：2011-07-01 00:00:00

abstract：:A simple method is described for the precise quantification of infectious duck hepatitis B virus (DHBV) in cell culture, using a radioimmunofocus assay (RIFA). Primary duck hepatocyte cell cultures were infected with serial dilutions of viral samples as for a plaque assay, but then maintained with liquid overlay mediu...

journal_title：Journal of medical virology

authors： Anderson DA,Grgacic EV,Luscombe CA,Gu X,Dixon R

更新日期：1997-08-01 00:00:00

abstract：:The infection of enterovirus 71 (EV71) resulted in hand, foot, and mouth disease and may lead to severe nervous system damage and even fatalities. There are no effective drugs to treat the EV71 virus and it is crucial to find novel drugs against it. Polysaccharide isolated from Durvillaea antarctica green algae has an...

journal_title：Journal of medical virology

authors： Xu T,Li Y,Wu HL,Chen H,Wu H,Guo M,Zhao M,Wang C,Lin T,Lin Z,Chen D,Xiang W,Zhu B

更新日期：2020-11-24 00:00:00

abstract：:Shedding of herpes simplex virus type 1 (HSV-1) into saliva was studied in 83 patients with orofacial fractures. Infectious virus was isolated from 14 of 83 patients (16.8%) with no detectable herpetic lesion during hospitalization. Of the 83 patients, 44 (53%) had HSV-1 specific antibody. Virus shedding into saliva w...

journal_title：Journal of medical virology

authors： Kameyama T,Futami M,Nakayoshi N,Sujaku C,Yamamoto S

更新日期：1989-06-01 00:00:00

abstract：:In this study, recombinant hemagglutinin protein (rH1N1HA) of Pandemic influenza virus and polyclonal antibodies against it for biosensor applications have been characterized. For rapid and high sensitive detection of H1N1 virus or its antibodies, PCR-free and label free detection method based on a surface plasmon res...

journal_title：Journal of medical virology

authors： Athmaram TN,Saraswat S,Sikarwar B,Verma SK,Singh AK,Boopathi M

更新日期：2014-03-01 00:00:00

abstract：:Rotavirus is a major cause of gastroenteritis in young children worldwide. There have been several recent reports concerning rotavirus isolation from adults, particularly in the elderly, presenting with gastroenteritis. In this study, the authors report on rotavirus outbreaks in five separate elderly care facilities b...

journal_title：Journal of medical virology

authors： Gunn L,Feeney SA,Cashman O,Collins PJ,Coyle PV,O'Shea H

更新日期：2012-12-01 00:00:00

abstract：:Passively administered antibodies to conserved epitopes on the attachment (G) glycoprotein of human respiratory syncytial virus (hRSV) have potential in the immunoprophylaxis of human infections. This study set out to generate monoclonal antibodies (MAbs) recognizing all prevalent lineages of HRSV and capable of immun...

journal_title：Journal of medical virology

authors： Robinson MJ,Tan CS,Fenwick F,Chambers CJ,Routledge EG,Toms GL

更新日期：2014-07-01 00:00:00

abstract：:This study analyzed the genotype distribution and frequency of lamivudine (LAM) and tenofovir (TDF) resistance mutations in a group of patients co-infected with HIV and hepatitis B virus (HBV). A cross-sectional study of 847 patients with HIV was conducted. Patients provided blood samples for HBsAg detection. The load...

journal_title：Journal of medical virology

authors： Mendes-Correa MC,Pinho JR,Locarnini S,Yuen L,Sitnik R,Santana RA,Gomes-Gouvêa MS,Leite OM,Martins LG,Silva MH,Gianini RJ,Uip DE

更新日期：2010-09-01 00:00:00

abstract：:Ultra violet (UV) light-inactivated measles virus was used for the lymphocyte proliferation assay, where it caused consistently adult human peripheral blood monolymphocytes (PBML) proliferation which was not dependent on the measles virus complement fixation titre in the donor's sera. When the cord blood lymphocytes f...

journal_title：Journal of medical virology

authors： Tu R

更新日期：1995-06-01 00:00:00

abstract：:Many countries are studying currently the possibility of mass vaccination against varicella. The objective of this study was to provide a complete picture of the pre-vaccine epidemiology of the Varicella-Zoster Virus in England and Wales to aid in the design of immunisation programs. Population-based data including ge...

journal_title：Journal of medical virology

authors： Brisson M,Edmunds WJ

更新日期：2003-01-01 00:00:00

abstract：:Coronavirus disease-2019 (COVID-19) infection and its severity can be explained by the concentration of glycosylated severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) viral particles in the lung epithelium, the concentration of glycosylated angiotensin-converting enzyme receptor 2 (ACE2) in the lung epithel...

journal_title：Journal of medical virology

authors： Brufsky A

更新日期：2020-07-01 00:00:00

abstract：:From November 2004 to April 2007, specimens were obtained from 2,281 patients with acute respiratory tract illness in Normandy, France. Eighteen strains of influenza C virus were detected in these samples using a combined tissue culture/RT-PCR diagnostic method. Most patients with influenza C virus infection (13/18) w...

journal_title：Journal of medical virology

authors： Gouarin S,Vabret A,Dina J,Petitjean J,Brouard J,Cuvillon-Nimal D,Freymuth F

更新日期：2008-08-01 00:00:00

abstract：:Serum samples from 87 patients with hepatocellular carcinoma (HCC) in the United States were tested for evidence of hepatitis C viral (HCV) infection using an immunoblot assay for antibodies to the hepatitis C virus and the polymerase chain reaction to detect HCV RNA. The findings with these assays were compared to th...

journal_title：Journal of medical virology

authors： Mangia A,Vallari DS,Di Bisceglie AM

更新日期：1994-06-01 00:00:00

abstract：:In order to analyse the relationships between enteroviral replication and the myocardial damage at the onset of chronic cardiac infection, 2 mouse strains with different degrees of immunological competence (NMRI nu/nu, DBA/2) were infected by a myocarditic Coxsackie virus B3 (CVB3-M1) variant. At 31 days post-inoculat...

journal_title：Journal of medical virology

authors： Andréoletti L,Hober D,Becquart P,Belaich S,Copin MC,Lambert V,Wattré P

更新日期：1997-06-01 00:00:00

abstract：:Persistent Epstein-Barr virus (EBV) infection is controlled tightly by virus-specific T cells. EBV infection is reactivated intermittently over time, even in apparently healthy carriers. Changes in frequency and reactivity of memory T cells, particularly of CD8(+) origin, have not been assessed in this context. It is ...

journal_title：Journal of medical virology

authors： Vogl BA,Fagin U,Nerbas L,Schlenke P,Lamprecht P,Jabs WJ

更新日期：2012-01-01 00:00:00

abstract：:HIV-1 replicative activity and its relation to the clinical and immunological evolution of infection was studied in a group of 150 HIV-1 seropositive Italian i.v. drug abusers over a 1 year period. HIV-1 was isolated from 90 (60%) subjects; two groups of isolates were distinguished, according to replicative activity "...

journal_title：Journal of medical virology

authors： Fiore JR,Calabró ML,Angarano G,De Rossi A,Fico C,Pastore G,Bianchi LC

更新日期：1990-12-01 00:00:00

abstract：:HCV strains belonging to genotype 4 may be gaining endemicity across Continental Europe but the extent of their spread in the United Kingdom is unknown. Sera referred from patients attending hospitals in England between 2004 through 2008 were characterised. A total of 243 sera carried HCV genotype 4. The most common s...

journal_title：Journal of medical virology

authors： Ngui SL,Brant L,Markov PV,Tung JP,Pybus OG,Teo CG,Ramsay ME

更新日期：2015-03-01 00:00:00