Abstract:
:Herpes simplex virus can be quantitatively recovered from vaginal tampons suspended in tissue culture medium and stored over a wide range of temperatures. Because herpes simplex virus is stable for several days with refrigeration or after freezing, this method of culture of cervicovaginal virus lends itself to epidemiologic studies.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Myers MG,Ekwo EE,Pitts AKdoi
10.1002/jmv.1890030306subject
Has Abstractpub_date
1979-01-01 00:00:00pages
203-6issue
3eissn
0146-6615issn
1096-9071journal_volume
3pub_type
杂志文章abstract::Does anal HPV viral load explain the difference in anal HPV persistence between HIV-negative and -positive men who have sex with men (MSM)? MSM ≥18 years were recruited in Amsterdam, the Netherlands, in 2010-2011. Anal self-swabs were collected every 6 months and genotyped (SPF10 -PCR-DEIA-LIPA25 -system). HPV16 and H...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24898
更新日期:2018-01-01 00:00:00
abstract::An attempt was made to identify factors influencing the cumulative probability of an increased alanine aminotransferase (ALT) level and hepatocarcinogenesis in hepatitis C patients with a normal ALT level initially. A total of 398 consecutive patients with a normal ALT level initially for 6 months or more and follow-u...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21342
更新日期:2009-03-01 00:00:00
abstract::Human sapoviruses (SaVs) are a common cause of the acute gastroenteritis epidemic worldwide, and SaV outbreaks and infections have become more frequent in recent years. Since the end of December, 2015 to December, 2016, 2 gastroenteritis outbreaks occurred in 2 kindergarten classes (outbreaks A and B) in the Baoan dis...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25236
更新日期:2018-11-01 00:00:00
abstract::Hepatitis C virus (HCV), exhibits considerable genetic diversity, but presents a relatively well conserved 5' noncoding region (5' NCR) among all genotypes. In this study, the structural features and translational efficiency of the HCV 5' NCR sequences were analyzed using the programs RNAfold, RNAshapes and RNApdist a...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21507
更新日期:2009-07-01 00:00:00
abstract::ZIKV infection has become a global threat spreading across 31 countries in Central America, South America, and the Caribbean. However, little information is available about the molecular epidemiology of ZIKV. Shared mutation of a threonine residue to alanine at the same position in the C terminal of NS5 sequences was ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24615
更新日期:2016-10-01 00:00:00
abstract::Serum levels of interleukin-6 (IL-6) are elevated in acute and chronic hepatitis B patients. The effect of IL-6 and its transcription factor of NF-IL6 (a nuclear factor for IL-6) on hepatitis B virus (HBV) enhancer 1 (Enh1), which controls HBV X expression, were investigated in HepG2 cells. Twenty ng/ml of IL-6 increa...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199708)52:4<413::aid-jmv12
更新日期:1997-08-01 00:00:00
abstract::This is a case study of a child who developed roseola infantum first, then varicella, and was later affected by acute cerebellar syndrome, severe truncal ataxia, and myoclonic dystonia. Human herpesvirus 6 (HHV-6) A and B were detected in the cerebrospinal fluid (CSF) and peripheral blood, respectively, upon ataxia on...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20285
更新日期:2005-03-01 00:00:00
abstract::Norovirus (NoV) is a causative agent of gastroenteritis in children and adults worldwide. Although reverse transcription-polymerase chain reaction (RT-PCR) has been accepted as the standard method for diagnosis of NoV infection, it requires well-trained personnel and sophisticated equipments. Performance of a commerci...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21916
更新日期:2010-12-01 00:00:00
abstract::Hepatitis C virus (HCV) particles can be classified into two major fractions according to their floating density in serum. However, the genomic heterogeneity of each fraction and the relationship between this viral characteristic and interferon (IFN) response in patients with chronic hepatitis are not known. In this s...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract::No data on antiviral response of HBV genotypes E-H are available so far although these HBV genotypes contribute significantly to the global HBV burden. Of 49 patients with HBV genotypes E-H, 23 received interferon (IFN)-alpha, 12 nucleos(t)ide analogues and 14 patients were untreated. HBV genotype was determined by di...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21588
更新日期:2009-10-01 00:00:00
abstract::Heterogeneity of hepatitis C viral (HCV) genomes of several isolates from different countries has been reported, but there is little information on HCV isolates for the Federal Republic of Germany. Therefore, the nucleotide (nt) and deduced amino acid (aa) sequences of interesting parts of the viral genome derived fro...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890400407
更新日期:1993-08-01 00:00:00
abstract::The occurrence of HIV infection among drug-users in Italy between 1990 and 2000 is described; the data concern drug-users attending a nation-wide network consisting of 510 public drug-treatment centres. We included only individuals with written documentation of an HIV-test result. Of the 1,299,972 attendees, 54.5% had...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20054
更新日期:2004-05-01 00:00:00
abstract::Passively administered antibodies to conserved epitopes on the attachment (G) glycoprotein of human respiratory syncytial virus (hRSV) have potential in the immunoprophylaxis of human infections. This study set out to generate monoclonal antibodies (MAbs) recognizing all prevalent lineages of HRSV and capable of immun...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23881
更新日期:2014-07-01 00:00:00
abstract::Enterovirus D68 (EV-D68) is an emergent viral pathogen associated with mild to severe respiratory infections. In this study, we describe respiratory infections associated with EV-D68 in Beijing over a 4 year period. Total nucleic acid was extracted from 7,945 clinical specimens collected between January 5, 2011 and Ju...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24505
更新日期:2016-09-01 00:00:00
abstract::To provide background for future hepatitis A vaccine trials, sera were collected from 0- to 4-year-old Liberian infants and their mothers on two occasions an average of 14.75 months apart and tested for antibody to hepatitis A virus (anti-HAV). The prevalence of anti-HAV rose from 2.5% in infants 0-6 months of age to ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890150411
更新日期:1985-04-01 00:00:00
abstract::Human T-lymphotropic virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is characterized by long periods of clinical latency with low levels of viral production. Transcription of HTLV-1 is controlled through sequences in the promoter and enhancer regions of the long terminal repeat of the integrated prov...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:2000-10-01 00:00:00
abstract::Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG dinucleotides within the context of certain flanking bases (CpG motifs) have been shown to induce potent innate and adaptive immune responses. Vaginal delivery of CpG ODN alone protects mice from vaginal herpes simplex virus type-2 (HSV-2) challenge. He...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10518
更新日期:2003-12-01 00:00:00
abstract::Palatine tonsils have been observed to harbor several distinct respiratory and herpesviruses in separate studies. In this study, the presence of these viruses in palatine tonsils was comprehensively studied in both children and adults. A cross-sectional analysis of 181 patients (median age 22 years; range, 2.6-66) ope...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26245
更新日期:2020-06-30 00:00:00
abstract::Hepatitis A virus (HAV) is the leading cause of acute viral hepatitis worldwide, with HAV infection being restricted to humans and nonhuman primates. In this study, HAV infection status was serologically determined in domestic pigs and experimental infections of HAV were attempted to verify HAV infectivity in pigs. An...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24386
更新日期:2016-04-01 00:00:00
abstract::A small percentage of renal patients become infected with the BK polyomavirus (BKV), a pathogenic virus that causes BKV-associated nephropathy (BKVN), after kidney transplantation. This study presents a simple, rapid, high-throughput method for BKV genotyping using high-resolution melt analysis (HRMA). Using this nove...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22239
更新日期:2011-12-01 00:00:00
abstract::Fluorescent in situ hybridization (FISH) was used to investigate the chromosomal integration sites of human herpesvirus 6 (HHV-6) in phytohemagglutinin-stimulated leukocytes and B lymphocytes from Epstein-Barr virus transformed lymphoblastoid cell lines (LCLs). Five different chromosomal integration sites were found i...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21299
更新日期:2008-11-01 00:00:00
abstract::In patients infected with the hepatitis C virus (HCV), a heterogeneous population of viruses, so-called quasispecies exists in vivo. The hypervariable regions (HVR) within the second envelope gene (HCV-E2) show particularly highly intratypic variability and are considered to be the target of neutralizing antibodies. T...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199711)53:3<245::aid-jmv11
更新日期:1997-11-01 00:00:00
abstract::During Epstein-Barr virus (EBV) latency, the EBV genome is largely silenced by methylation. This silencing is overturned during the switch to the lytic cycle. A key event is the production of the viral protein Zta which binds to three Zta-response elements (ZRE) from the Rta promoter (Rp), two of which (ZRE2 and ZRE3)...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24524
更新日期:2016-10-01 00:00:00
abstract::A polymerase chain reaction-restriction (PCR-restriction) endonuclease assay was developed to allow rapid analysis of influenza A H3N2 viruses circulating in England during 1995-1996. Restriction endonuclease digestion with two enzymes of amplicons derived from PCR of the HA1 portion of the influenza haemagglutinin (H...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::In April 2004, two patients were admitted to hospital in Berlin, Germany, with clinical signs of acute respiratory infection after returning from a military exercise in their home country of Turkey. They were admitted to a high security infectious disease unit as epidemiological data pointed to an outbreak of unknown ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20441
更新日期:2005-10-01 00:00:00
abstract::Inosine triphosphatase (ITPA) gene variants can protect against ribavirin (RBV)-induced anemia in patients treated for chronic hepatitis C. The aim of this study was to determine the relationship between genetic variants of ITPA polymorphism, anemia, RBV dose reduction, and treatment response in hepatitis C virus (HCV...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24844
更新日期:2017-10-01 00:00:00
abstract::Lack of recognition of human immunodeficiency virus (HIV) infection especially in children and delayed implementation of effective control programs makes HIV infection as a major cause for concern. Information on HIV epidemiology in Iran as well as other Islamic countries is limited. The aim of our study was to descri...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24294
更新日期:2016-01-01 00:00:00
abstract::The quantification of human immunodeficiency virus type 1 (HIV-1) RNA or hepatitis C virus (HCV) RNA has been facilitated by adapting a spin column procedure for sample preparation and the use of chemiluminescent detection of polymerase chain reaction (PCR) products in microtiter plate format. All materials were comme...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Little information about immunity to respiratory syncytial virus (RSV) and disease pathogenesis in elderly persons exists. Humoral immunity to RSV was assessed in 41 young, 56 healthy elderly, and 49 frail elderly adults by measuring baseline RSV specific IgG by enzyme immunoassay (EIA) and microneutralization assay (...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199910)59:2<221::aid-jmv16
更新日期:1999-10-01 00:00:00
abstract::SARS-CoV-2 infection is causing a pandemic disease that is reflected in challenging public health problems worldwide. Human leukocyte antigen (HLA)-based epitope prediction and its association with disease outcomes provide an important base for treatment design. A bioinformatic prediction of T cell epitopes and their ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26561
更新日期:2020-09-28 00:00:00