Floating density of hepatitis C virus particles and response to interferon treatment.

abstract：:A viable virus could not be recovered from a mutant murine cytomegalovirus (MCMV) BAC in which the M34 ORF had been deleted (BACDeltaM34). In contrast, an M34 mutant virus (RcM34), in which the M34 ORF was interrupted by transposon insertion at nt 44,827 of the Smith MCMV BAC, was attenuated in replication both in tis...

journal_title：Journal of medical virology

authors： Baluchova K,Kirby M,Ahasan MM,Sweet C

更新日期：2008-07-01 00:00:00

abstract：:HIV diagnosis at the point-of-care or in resource-limited settings poses considerable challenges due to time and cost limitations. Currently, nucleic acid-based tests are the only reliable method for diagnosing recent infections during the window period post-infection and pre-seroconversion, but these tests are only s...

journal_title：Journal of medical virology

authors： Curtis KA,Rudolph DL,Owen SM

更新日期：2009-06-01 00:00:00

abstract：:The detection of hepatitis B virus (HBV) DNA plays a critical role in determining the level of viral replication in HBV-infected patients. However, how to select appropriate HBV DNA detection method, low-sensitivity (ls) and hypersensitivity (hs) remains unclear. In this study, hepatitis B surface antigen (HBsAg), hep...

journal_title：Journal of medical virology

authors： Liu C,Wu W,Shang S,Huang E,Xun Z,Lin J,Chen T,Yang B,Chen J,Ou Q

更新日期：2019-02-01 00:00:00

abstract：:Major differences exist between HIV-1 and HIV-2 in terms of epidemiology, pathogenicity, sensitivity to antiretrovirals. Determining the type of HIV infecting a patient is essential for management. The aim of this study was to evaluate the ability of simple/rapid tests to differentiate between HIV-1 and/or HIV-2 infec...

journal_title：Journal of medical virology

authors： Gautheret-Dejean A,Bocobza J,Brunet S,Damond F,Plantier JC,Barin F

更新日期：2015-12-01 00:00:00

abstract：:Cytomegalovirus (CMV) is the most common congenital infection in humans and a leading cause of sensorineural hearing loss. Ganciclovir (6 mg/kg twice daily for 42 days) has been shown to reduce hearing deterioration and is used in clinical practice. Vaccines and passive administration of antibody are being evaluated i...

journal_title：Journal of medical virology

authors： Kadambari S,Atkinson C,Luck S,Macartney M,Conibear T,Harrison I,Booth C,Sharland M,Griffiths PD

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:Although the effectiveness of direct-acting antivirals (DAAs) for the treatment of chronic hepatitis C virus (HCV) has been reported in real-world settings, predictive factors of treatment failure are lacking. Therefore, we sought to explore the baseline predictors of treatment response to DAAs. METHODS:T...

journal_title：Journal of medical virology

authors： Ridruejo E,Piñero F,Mendizabal M,Cheinquer H,Wolff FH,Anders M,Reggiardo V,Ameigeiras B,Palazzo A,Alonso C,Schinoni MI,Zuain MGV,Tanno F,Figueroa S,Santos L,Peralta M,Soza A,Vistarini C,Adrover R,Fernández N,Perez

更新日期：2020-08-04 00:00:00

abstract：:Although there is a low prevalence rate (around 1% of the population) of infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in Chile, little is known about the diversity and molecular characteristics of the circulating viruses. In the present study, 40 HBV and 57 HCV samples from Santiago City, Chile, ...

journal_title：Journal of medical virology

authors： Di Lello FA,Piñeiro Y Leone FG,Muñoz G,Campos RH

更新日期：2009-11-01 00:00:00

abstract：:Since outbreaks of severe acute hemorrhagic conjunctivitis occur worldwide [Hierholzer and Hatch, 1985] and the majority of the epidemics are caused by enterovirus 70 (EV-70), we developed an EV-70 IgM ELISA to simplify the diagnosis of these outbreaks. The test is based on the capture antibody technique and the use o...

journal_title：Journal of medical virology

authors： Wulff H,Anderson LJ,Pallansch MA,de Souza Carvalho RP

更新日期：1987-04-01 00:00:00

abstract：:Latency associated peptide (LAP) is a protein expressed on the membrane of some regulatory T cells (Treg). LAP+ Treg have a greater immunomodulatory effect than that of their negative counterparts. In this study, we presented the data on the proportion of LAP+ Treg out of CD4+ cells in mice with viral myocarditis, whi...

journal_title：Journal of medical virology

authors： Wang X,Ge J,Chen R

更新日期：2019-05-01 00:00:00

abstract：:Most cases of hepatocellular carcinoma (HCC) are due to chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection worldwide. The aim of this study was to determine the viral genotypes and frequency of 17 mutations (15 for HBV and 2 for HCV), described previously as able to influence the course of chronic li...

journal_title：Journal of medical virology

authors： Araujo OC,Barros JJ,do Ó KM,Nabuco LC,Luz CA,Perez RM,Niel C,Villela-Nogueira CA,Araujo NM

更新日期：2014-02-01 00:00:00

abstract：:The objective of this study was to investigate variation in human papillomavirus (HPV) type-16 load within histologically defined grades of cervical intraepithelial neoplasia. Two hundred and thirty-seven liquid based cytology samples were collected from women attending colposcopy clinics, DNA was extracted, and prese...

journal_title：Journal of medical virology

authors： Fiander AN,Hart KW,Hibbitts SJ,Rieck GC,Tristram AJ,Beukenholdt RW,Powell NG

更新日期：2007-09-01 00:00:00

abstract：:This is a case study of a child who developed roseola infantum first, then varicella, and was later affected by acute cerebellar syndrome, severe truncal ataxia, and myoclonic dystonia. Human herpesvirus 6 (HHV-6) A and B were detected in the cerebrospinal fluid (CSF) and peripheral blood, respectively, upon ataxia on...

journal_title：Journal of medical virology

authors： Borghi E,Pagani E,Mancuso R,Delbue S,Valli M,Mazziotti R,Giordano L,Micheli R,Ferrante P

更新日期：2005-03-01 00:00:00

abstract：:No controlled trial in patients with chronic hepatitis B virus (HBV) infection on long-term entecavir (ETV) treatment, comparing switching to tenofovir disoproxil fumarate (TDF) with continuing the therapy, has been reported. Twenty-seven nucleos(t)ide-naïve patients with chronic HBV who underwent ETV therapy for ≥5 y...

journal_title：Journal of medical virology

authors： Iida-Ueno A,Enomoto M,Kozuka R,Tamori A,Kawada N

更新日期：2019-07-01 00:00:00

abstract：:Genital herpes is a common, distressing infection whose incidence has been underestimated. Recent serological surveys, employing type-specific antibody assays, show a rising prevalence of previous herpes simplex virus (HSV) type 2 infections in post-adolescent populations in developed countries; many of these infectio...

journal_title：Journal of medical virology

authors： Kinghorn GR

更新日期：1993-01-01 00:00:00

abstract：:Occult HBV infection is defined as the persistence of HBV DNA in individuals negative for HBV surface antigen (HBsAg), and many different mechanisms have been reported in different countries. However, in China, one of the endemic areas for HBV infection, no reports have been published on occult HBV infection. The pres...

journal_title：Journal of medical virology

authors： Fang Y,Teng X,Xu WZ,Li D,Zhao HW,Fu LJ,Zhang FM,Gu HX

更新日期：2009-05-01 00:00:00

abstract：:A previous study revealed a high prevalence of hepatitis B surface antigen (HBsAg) and hepatitis delta virus (HDV) RNA among 249 apparently healthy individuals (mean+/-standard deviation age, 48.4+/-13.9 years; 126 males and 123 females) in Ulaanbaatar, Mongolia. To investigate further the prevalence of HDV infection ...

journal_title：Journal of medical virology

authors： Inoue J,Takahashi M,Nishizawa T,Narantuya L,Sakuma M,Kagawa Y,Shimosegawa T,Okamoto H

更新日期：2005-07-01 00:00:00

abstract：:Oral DAA have demonstrated high efficacy as treatment of hepatitis C. However, the presence of resistance-associated substitutions (RAS) at baseline has occasionally been associated with impaired treatment response. Herein, we examined the impact of baseline RAS at the HCV NS5A gene region on treatment response in a r...

journal_title：Journal of medical virology

authors： Carrasco I,Arias A,Benítez-Gutiérrez L,Lledó G,Requena S,Cuesta M,Cuervas-Mons V,de Mendoza C

更新日期：2018-03-01 00:00:00

abstract：:Virological studies were carried out on 3 to 36-month-old patients admitted to the Children's Hospital of the University of Modena with febrile syndrome from September 1990 to February 1991. Virological tests were carried out for human herpesvirus-6 (HHV-6), Epstein-Barr virus (EBV), cytomegalovirus (CMV), herpes simp...

journal_title：Journal of medical virology

authors： Portolani M,Cermelli C,Moroni A,Bertolani MF,Di Luca D,Cassai E,Sabbatini AM

更新日期：1993-02-01 00:00:00

abstract：:It was reported previously that HCV can be transmitted from persistently infected human bone-marrow-derived B-lymphoblastoid cells (TO.FE(HCV)) to human hepatoma cells by cell-to-cell contact. The present study confirms and characterize further such type of HCV infection in vitro. TO.FE(HCV) cells were co-cultured wit...

journal_title：Journal of medical virology

authors： Valli MB,Crema A,Lanzilli G,Serafino A,Bertolini L,Ravagnan G,Ponzetto A,Menzo S,Clementi M,Carloni G

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Seasonal influenza is an annual occurrence that leads to large community outbreaks and increased hospitalisation. A number of studies have suggested that influenza A (FLUAV) is associated with increased rates of hospitalisation and mortality compared to influenza B (FLUBV). This study compared demographic an...

journal_title：Journal of medical virology

authors： Mabayoje DA,Cutino-Moguel T,Haigh J,Wilks M,Welch CA,Melzer M

更新日期：2020-10-15 00:00:00

abstract：:The ability of a variety of epithelial, embryonal, placental, and neuronal cells to express the CD4 antigen and to be infected by human immunodeficiency virus 1 (HIV-1) was examined. Only two (IMR-32 and HeLa-T4) expressed CD4 detectable by indirect immunofluorescence, and both were infectable by HIV-1. Two others, a ...

journal_title：Journal of medical virology

authors： Morrison NK,McCarthy K,Hart CA

更新日期：1991-11-01 00:00:00

abstract：:The seroprevalence of viral hepatitis in healthcare workers has important public health implications. To assess the risk factors for the acquisition of viral hepatitis in an unvaccinated cohort from an hyperendemic region, 567 healthcare workers from a large hospital in the capital of the Republic of Yemen were interv...

journal_title：Journal of medical virology

authors： Shidrawi R,Ali Al-Huraibi M,Ahmad Al-Haimi M,Dayton R,Murray-Lyon IM

更新日期：2004-08-01 00:00:00

abstract：:In order to assess the current seroepidemiology of hepatitis D virus (HDV) infection in Taiwan where hepatitis B virus (HBV) is hyperendemic, a total of 756 voluntary blood donors, 641 prostitutes, 1,014 patients with sexually transmitted diseases (STDs), and 628 drug abusers were studied. Radioimmunoassays were used ...

journal_title：Journal of medical virology

authors： Chen CJ,Tseng SF,Lu CF,Lin HC,You SL,Chen CS,Hwang SJ,Hsieh SF,Hsu ST

更新日期：1992-10-01 00:00:00

abstract：:The nature of the immunodominant a region of hepatitis B virus surface antigen (HBsAg) has been examined by mutation of specific amino acid residues. Proline 142 was required for the exhibition of full antigenicity. Replacement of cysteines 124 and 147 by serines drastically reduced or eliminated reactivity with antib...

journal_title：Journal of medical virology

authors： Ashton-Rickardt PG,Murray K

更新日期：1989-11-01 00:00:00

abstract：:Foscarnet (trisodium phosphonoformate) is a novel antiviral agent that inhibits viral-specific DNA polymerase. In the present study, eight males with chronic HBV carriage (HBeAg and HBV-DNA seropositivity greater than 12 months) showing chronic persistent hepatitis (CPH) or chronic active hepatitis (CAH) on liver biop...

journal_title：Journal of medical virology

authors： Bain VG,Daniels HM,Chanas A,Alexander GJ,Williams R

更新日期：1989-10-01 00:00:00

abstract：:To determine whether unconventional pathogens causing subacute spongiform encephalopathy may be present in blood products, a newly developed hepatitis B vaccine and a widely used blood product were injected into mice and rats. As only a few aged mice in the test and the control groups showed spongiform encephalopathic...

journal_title：Journal of medical virology

authors： Tateishi J,Tsuji S

更新日期：1985-05-01 00:00:00

abstract：:In vitro incubation of human cytomegalovirus (Towne strain) with 8 U/ml human recombinant myeloperoxidase plus sodium chloride and glucose nearly abolished viral infectivity. To assay the effect on intracellular infection, cell toxicity of the enzymes was first studied. Even the high dose of 16 U/ml of recombinant mye...

journal_title：Journal of medical virology

authors： El Messaoudi K,Verheyden AM,Thiry L,Fourez S,Tasiaux N,Bollen A,Moguilevsky N

更新日期：2002-02-01 00:00:00

abstract：:Over the past decade, a G4P[6] strain has been found to be circulating in different neonatal wards in the Pretoria area. This endemic strain was associated with both asymptomatic and symptomatic infection, providing the opportunity to undertake a molecular study of some of the putative "virulence" genes. The genes enc...

journal_title：Journal of medical virology

authors： Pager CT,Alexander JJ,Steele AD

更新日期：2000-10-01 00:00:00

abstract：:Hantavirus infection during pregnancy can influence both maternal and fetal outcomes. Here, we describe four cases of hemorrhagic fever with renal syndrome (HFRS) in pregnant Chinese women. The HFRS put these women at increased risk for severe illness, despite the patients' symptomologies in the onset phase were simil...

journal_title：Journal of medical virology

authors： Ji F,Zhao W,Liu H,Zheng H,Wang S,He C,Wang W,Zhang R,Bai D,Tian C,Zhao W,Deng H

更新日期：2017-10-01 00:00:00

abstract：:It is need for development of new means against influenza virus due to the lack of efficacy of available therapeutic strategies. In previous research, 1,8-cineol exert its inhibition of nuclear factor (NF)-κB, the main regulator of cytokine and chemokine production in influenza, and anti-inflammatory activity. These f...

journal_title：Journal of medical virology

authors： Lai YN,Li Y,Fu LC,Zhao F,Liu N,Zhang FX,Xu PP

更新日期：2017-07-01 00:00:00