Growth of human immunodeficiency virus I in cultured cells in the absence of the CD4 antigen.

abstract：:HCV replication in extra-hepatic reservoirs has been suggested to occur in many tissues including PBMCs. A recent study showed evidence for compartmentalization and evolution of HCV in PBMCs. However, the cells that support HCV replication in PBMCs have not been identified. In this study we have fractionated the PBMC ...

journal_title：Journal of medical virology

authors： Natarajan V,Kottilil S,Hazen A,Adelsberger J,Murphy AA,Polis MA,Kovacs JA

更新日期：2010-12-01 00:00:00

abstract：:Regulatory T cells (T(reg)) provide a balance to immune T cell activation thereby protecting the body from pathogen-induced immunopathology. Several persistent viruses induce T(reg) that subvert protective immune mechanisms and promote viral persistence. Epstein-Barr virus (EBV) generally infects children subclinicall...

journal_title：Journal of medical virology

authors： Wingate PJ,McAulay KA,Anthony IC,Crawford DH

更新日期：2009-05-01 00:00:00

abstract：:The aims of the present study were to confirm measles outbreaks by detection of measles-specific IgM antibodies, isolation of measles virus, and genetic characterization to document the circulating genotypes in Tamil Nadu. Eight outbreaks were reported from six districts of Tamil Nadu, India during the period Jan-Dec ...

journal_title：Journal of medical virology

authors： Ramamurty N,Raja D,Gunasekaran P,Varalakshmi E,Mohana S,Jin L

更新日期：2006-04-01 00:00:00

abstract：:Hemorrhagic fever with renal syndrome (HFRS) is a severe acute viral disease with pathological changes of impaired capillary and small vessels and thrombocytopenia. In this study, serum thrombospondin (TSP)-1 concentration in patients with HFRS was determined to explore its possible role in the pathogenesis of HFRS. T...

journal_title：Journal of medical virology

authors： Liu Z,Zhao Q,Han Q,Gao M,Zhang N

更新日期：2008-10-01 00:00:00

abstract：:Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBV-DNA after a self-limited acute hepatitis B. This may also occur in patients with chronic hepatitis C virus (HCV) infection but its prevalence and its impact on liver histology is unknown. HBV-DNA was tested by polymerase chain reaction (P...

journal_title：Journal of medical virology

authors： Mariscal LF,Rodríguez-Iñigo E,Bartolomé J,Castillo I,Ortiz-Movilla N,Navacerrada C,Pardo M,Pérez-Mota A,Graus J,Carreño V

更新日期：2004-06-01 00:00:00

abstract：:Knowledge of the antigenic diversity of rotaviruses circulating in a region should be acquired before introducing a rotavirus vaccine. In a collection of 151 rotavirus-positive samples from Mendoza, Argentina, strain diversity was evaluated utilizing G-typing monoclonal antibodies (MAbs), reverse-transcriptase-polymer...

journal_title：Journal of medical virology

authors： Espul C,Cuello H,Martinez N,Centorbi O,O'Ryan M,Jackson L,Campos F,Matson DO

更新日期：2000-08-01 00:00:00

abstract：:Human rhinovirus (HRV), a single-stranded, positive-sense RNA virus, is associated with mild upper respiratory tract infections in children. The aim of this study was to carry out a molecular characterization and phylogeny-based classification of the circulating genotypes of HRV in hospitalized children with clinical ...

journal_title：Journal of medical virology

authors： Espínola EE,Russomando G,Aquino C,Basualdo W

更新日期：2013-09-01 00:00:00

abstract：:Mixed cryoglobulinemia is a lymphoproliferative disorder associated with hepatitis C virus (HCV). In patients chronically affected by HCV the prevalence of mixed cryoglobulinemia is variable ranging from 0% to 56%. To verify whether polyomaviruses (PyV) play a role in this disorder a total of 222 blood samples from 63...

journal_title：Journal of medical virology

authors： Comar M,Zanotta N,Del Savio R,Vascotto F,Calabrese N,Zorat F,Pozzato G

更新日期：2014-04-01 00:00:00

abstract：:Fifty-six renal allograft recipients were studied prospectively for 3 months or longer after transplant. The polymerase chain reaction (PCR) was used to screen peripheral blood leucocyte (PBL) specimens for CMV, human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7) DNA (DNAemia) in 67 healthy controls and in seria...

journal_title：Journal of medical virology

authors： Osman HK,Peiris JS,Taylor CE,Warwicker P,Jarrett RF,Madeley CR

更新日期：1996-04-01 00:00:00

abstract：:Genotype 1F was likely localized geographically to China as it has not been reported elsewhere. In this study, whole genome sequences of two rubella 1F virus isolates were completed. Both viruses contained 9,761 nt with a single nucleotide deletion in the intergenic region, compared to the NCBI rubella reference seque...

journal_title：Journal of medical virology

authors： Zhu Z,Chen MH,Abernathy E,Zhou S,Wang C,Icenogle J,Xu W

更新日期：2014-12-01 00:00:00

abstract：:Enteroviruses are responsible for hand, foot, and mouth disease, and have caused many deaths in China during recent years. But the natural history of enterovirus infection in children, especially asymptomatic children, is not yet clear. From April 2011 to May 2012, 505 stool and throat swab samples of children attendi...

journal_title：Journal of medical virology

authors： Cai J,Lv H,Lin J,Chen Z,Fang C,Han J

更新日期：2014-09-01 00:00:00

abstract：:It has been suggested that some individuals may present genetic susceptibility to SARS-CoV-2 infection, with particular research interest in variants of the ACE2 and TMPRSS2 genes, involved in viral penetration into cells, in different populations and geographic regions, although insufficient information is currently ...

journal_title：Journal of medical virology

authors： Torre-Fuentes L,Matías-Guiu J,Hernández-Lorenzo L,Montero-Escribano P,Pytel V,Porta-Etessam J,Gómez-Pinedo U,Matías-Guiu JA

更新日期：2021-02-01 00:00:00

abstract：:Limited amount of information is available in Taiwan on the genetic or antigenic characteristics of influenza A virus prior to the establishment of a Taiwan surveillance network in 2000. Isolates of H1N1 and H3N2 viruses in Taiwan between 1980 and 2006 were studied, and part of the hemagglutinin gene was analyzed due ...

journal_title：Journal of medical virology

authors： Wang SF,Lee YM,Chan YJ,Liu HF,Yen YF,Liu WT,Huang JC,Chen YM

更新日期：2009-08-01 00:00:00

abstract：:Norovirus (NoV) is a causative agent of gastroenteritis in children and adults worldwide. Although reverse transcription-polymerase chain reaction (RT-PCR) has been accepted as the standard method for diagnosis of NoV infection, it requires well-trained personnel and sophisticated equipments. Performance of a commerci...

journal_title：Journal of medical virology

authors： Thongprachum A,Khamrin P,Chaimongkol N,Malasao R,Okitsu S,Mizuguchi M,Maneekarn N,Ushijima H

更新日期：2010-12-01 00:00:00

abstract：:Human immunodeficiency virus 2 (HIV-2) infection is characterized by a slower disease progression and lower transmission rates. The molecular features that could be assigned as directly involved in this in vivo phenotype remain essentially unknown, and the importance of HIV-2 as a model to understand pathogenicity of ...

journal_title：Journal of medical virology

authors： Santos-Costa Q,Parreira R,Moniz-Pereira J,Azevedo-Pereira JM

更新日期：2009-11-01 00:00:00

abstract：:Because of the distinct ability of retroviruses to integrate into the target cell genome and thus achieve long-term expression, retrovirus vectors hold great promise for stable gene transfer. Such vectors derived from human immunodeficiency retroviruses (HIVs) and other lentiviruses are envisioned to possess several a...

journal_title：Journal of medical virology

authors： Sadaie MR,Zamani M,Whang S,Sistron N,Arya SK

更新日期：1998-02-01 00:00:00

abstract：:Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory t...

journal_title：Journal of medical virology

authors： Stelzer-Braid S,Liu N,Doumit M,D'Cunha R,Belessis Y,Jaffe A,Rawlinson WD

更新日期：2017-08-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) can lead to a massive cytokine release. The use of the anti-interleukin-6 receptor monoclonal antibody tocilizumab (TCZ) has been proposed in this hyperinflammatory phase, although supporting evidence is limited. We retrospectively analyzed 88 consecutive patients with COVID-19 pneu...

journal_title：Journal of medical virology

authors： Fernández-Ruiz M,López-Medrano F,Pérez-Jacoiste Asín MA,Maestro de la Calle G,Bueno H,Caro-Teller JM,Catalán M,de la Calle C,García-García R,Gómez C,Laguna-Goya R,Lizasoáin M,Martínez-López J,Origüen J,Pablos JL,Ripoll M,

更新日期：2021-02-01 00:00:00

abstract：:The relationships between host immune factors and HIV-1 disease progression are still in dispute. The RANTES SNPs exhibit distinct ethnic distribution and are associated with different effects on the course of HIV infection. Therefore, impact of RANTES gene polymorphism on HIV-1 transmission and progression needs to b...

journal_title：Journal of medical virology

authors： Rathore A,Chatterjee A,Sivarama P,Yamamoto N,Singhal PK,Dhole TN

更新日期：2008-07-01 00:00:00

abstract：:Human T-lymphotropic virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is characterized by long periods of clinical latency with low levels of viral production. Transcription of HTLV-1 is controlled through sequences in the promoter and enhancer regions of the long terminal repeat of the integrated prov...

journal_title：Journal of medical virology

authors： Newbound GC,O'Rourke JP,Collins ND,Andrews JM,DeWille J,Lairmore MD

更新日期：2000-10-01 00:00:00

abstract：:The complete RNA sequences of hepatitis delta viruses (HDV) isolated at 3 years apart from a chronic delta hepatitis patient in Taiwan were determined. The sequence analysis showed an overall evolution rate of 3.18 x 10(-3) substitutions/nucleotide/year. The evolution rates in different parts of HDV RNA varied. The hy...

journal_title：Journal of medical virology

authors： Chao YC,Tang HS,Hsu CT

更新日期：1994-08-01 00:00:00

abstract：:One hundred twenty strains of adenovirus types 1, 2, 5, and 6 (subgenus C), isolated at various times and places, were tested by neutralization and hemagglutination inhibition with two antisera of each type. Except for one type 5 strain they reacted largely type-specifically in both tests and neither qualitative nor q...

journal_title：Journal of medical virology

authors： Kaier B,Wigand R

更新日期：1986-03-01 00:00:00

abstract：:Shedding of herpes simplex virus type 1 (HSV-1) into saliva was studied in 83 patients with orofacial fractures. Infectious virus was isolated from 14 of 83 patients (16.8%) with no detectable herpetic lesion during hospitalization. Of the 83 patients, 44 (53%) had HSV-1 specific antibody. Virus shedding into saliva w...

journal_title：Journal of medical virology

authors： Kameyama T,Futami M,Nakayoshi N,Sujaku C,Yamamoto S

更新日期：1989-06-01 00:00:00

abstract：:Although there is a low prevalence rate (around 1% of the population) of infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in Chile, little is known about the diversity and molecular characteristics of the circulating viruses. In the present study, 40 HBV and 57 HCV samples from Santiago City, Chile, ...

journal_title：Journal of medical virology

authors： Di Lello FA,Piñeiro Y Leone FG,Muñoz G,Campos RH

更新日期：2009-11-01 00:00:00

abstract：:Human flavivirus group-reactive, dengue complex-reactive, and encephalitis virus complex-reactive antibodies were detected using epitope-blocking immunoassays in which the binding of selected mouse monoclonal antibodies to flavivirus antigens was blocked by human serum. When late (greater than 6 months after illness) ...

journal_title：Journal of medical virology

authors： Burke DS,Nisalak A,Gentry MK

更新日期：1987-10-01 00:00:00

abstract：:A method for the absorption of false radioimmunoassay (RIA) IgM titres against herpes simplex virus (HSV) and cytomegalovirus (CMV) is presented. The serum specimens were absorbed by a mixture of protein A-Sepharose and protein A-Sepharose saturated with normal human gamma globulin (PAS/IgG). The detection of rheumato...

journal_title：Journal of medical virology

authors： Torfason EG,Diderholm H

更新日期：1982-01-01 00:00:00

abstract：:Monoclonal antibodies were raised against hepatitis B core antigen (HBcAg) synthesized in Escherichia coli. They identified a single immunodominant determinant on both liver-derived and E. coli-derived HBcAg. Cross-inhibition studies demonstrated that HBsAg-containing human sera which contained antibodies to HBcAg (an...

journal_title：Journal of medical virology

authors： Ferns RB,Tedder RS

更新日期：1986-06-01 00:00:00

abstract：:The multiplication of HSV-1 and HSV-2 strains in the heart and the corresponding dorsal root ganglia (DRG) was examined in experimentally infected mice. Infectious HSV-1 was recovered from the heart between the second and fourth day after inoculation and 3 days later from the DRG. Both the heart and DRG yielded infect...

journal_title：Journal of medical virology

authors： Grodums EI,Kuling PJ,Zbitnew A

更新日期：1981-01-01 00:00:00

abstract：:Although analytical treatment interruption is used as a strategy to test immunotherapeutic agents in HIV-infection, it may pose a risk for study participants. The potential risks of short-term interruption of antiretroviral therapy (ART) during treatment with an autologous dendritic cell immune-based therapy (AGS-004-...

journal_title：Journal of medical virology

authors： Routy JP,Boulassel MR,Nicolette CA,Jacobson JM

更新日期：2012-06-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated malignant tumor. Recently, cidofovir, an anti-viral drug which is an acyclic nucleoside analogue, has been reported to have an anti-tumor potential. Two patients with NPC, who had previously received multi-round therapy, were treated with cidofov...

journal_title：Journal of medical virology

authors： Yoshizaki T,Wakisaka N,Kondo S,Murono S,Shimizu Y,Nakashima M,Tsuji A,Furukawa M

更新日期：2008-05-01 00:00:00