Assessing risk of a short-term antiretroviral therapy discontinuation as a read-out of viral control in immune-based therapy.

abstract：:Human respiratory syncytial virus (HRSV) is major pathogen of lower respiratory tract infections in infants and young children worldwide. There have been many studies regarding HRSV subgroup A (HRSV-A) G protein genetic variability but little information about HRSV subtype B (HRSV-B) G protein genetic diversity and mo...

journal_title：Journal of medical virology

authors： Ren L,Xiao Q,Zhou L,Xia Q,Liu E

更新日期：2015-01-01 00:00:00

abstract：:Guinea pig infection with a highly passaged XJ prototype strain of Junín virus by the intramuscular route (IM) was carried out in order to study viral tropism modification in this host. The neurotropism of this strain was demonstrated by viral isolation, meningitis, and by the presence of Junín antigens as shown by im...

journal_title：Journal of medical virology

authors： Oubiña JR,Carballal G

更新日期：1985-02-01 00:00:00

abstract：:Influenza is a public health burden, responsible for more than half a million deaths worldwide each year and explosive outbreaks in-hospital care units. At present, little is known about clinical characteristics and outcomes with nosocomial influenza infection. To assess clinical characteristics and outcome between no...

journal_title：Journal of medical virology

authors： Naudion P,Lepiller Q,Bouiller K

更新日期：2020-08-01 00:00:00

abstract：:Lymphocytic choriomeningitis virus (LCMV), which is one of several arenaviruses that are pathogenic for humans, causes encephalitis and meningitis in man. In this study, single-stage and nested reverse transcription-polymerase chain reaction (RT-PCR) assays were developed that targeted the GPC and N genes of LCMV. Bot...

journal_title：Journal of medical virology

authors： Park JY,Peters CJ,Rollin PE,Ksiazek TG,Gray B,Waites KB,Stephensen CB

更新日期：1997-02-01 00:00:00

abstract：:Shedding of herpes simplex virus type 1 (HSV-1) into saliva was studied in 83 patients with orofacial fractures. Infectious virus was isolated from 14 of 83 patients (16.8%) with no detectable herpetic lesion during hospitalization. Of the 83 patients, 44 (53%) had HSV-1 specific antibody. Virus shedding into saliva w...

journal_title：Journal of medical virology

authors： Kameyama T,Futami M,Nakayoshi N,Sujaku C,Yamamoto S

更新日期：1989-06-01 00:00:00

abstract：:Nine ducks congenitally infected with the duck hepatitis B virus (DHBV) were treated either orally (four ducks for 10 weeks) or intraperitoneally (five ducks for 12 weeks) with the Indian traditional herbal remedy Phyllanthus amarus. Compared to placebo-treated control ducks, these treatments did not result in a reduc...

journal_title：Journal of medical virology

authors： Niu JZ,Wang YY,Qiao M,Gowans E,Edwards P,Thyagarajan SP,Gust I,Locarnini S

更新日期：1990-12-01 00:00:00

abstract：:Early estimates of the prevalence of TTV viremia in healthy adults of developed countries were in the order of 1--10 %, while similar estimates in Third World countries were considerably higher. Using three different PCRs, TTV-related DNA was detected in serum from 180 out of the 201 Norwegian blood donors tested, ind...

journal_title：Journal of medical virology

authors： Huang LY,Oystein Jonassen T,Hungnes O,Grinde B

更新日期：2001-07-01 00:00:00

abstract：:In order to evaluate the true immune status and the effect of revaccination on a young adult population, we collected serum samples from 289 military recruits who were vaccinated during an outbreak in 1991. Most vaccinees, age 18-25 years, had apparently been immunized once before as infants. Sera collected just prior...

journal_title：Journal of medical virology

authors： Mendelson E,Duvdevani P,Varsano N,Lerman Y,Slepon R,Dagan R,Cohen D,Danon Y,Shohat T

更新日期：1996-11-01 00:00:00

abstract：:A solid phase enzyme linked immunosorbent assay (ELISA) that detects IgM and IgG to hepatitis E virus (HEV) was used to study seroepidemiology in 40 healthy subjects and 227 consecutive patients with liver diseases in an endemic area. Fifty-two of the liver diseases patients (22.9 percent) had acute hepatitis E. In co...

journal_title：Journal of medical virology

authors： Khuroo MS,Rustgi VK,Dawson GJ,Mushahwar IK,Yattoo GN,Kamili S,Khan BA

更新日期：1994-07-01 00:00:00

abstract：:Human bocavirus (HBoV) was first recognized in respiratory samples in 2005. The clinical importance of HBoV infection remains unclear. This report describes the clinical features and molecular phylogeny of HBoV isolates in children with acute respiratory infections. Nasopharyngeal aspirates were obtained from 1,528 ch...

journal_title：Journal of medical virology

authors： Ahn JG,Choi SY,Kim DS,Kim KH

更新日期：2014-12-01 00:00:00

abstract：:During 2002, an upsurge in frequency of hepatitis A outbreaks among injecting drug users was observed in England and Wales. As lack of risk factor information and the high mobility of the cases made linkage of outbreaks difficult, the relationship of nucleotide sequences in the VP1/2PA junction of the hepatitis A viru...

journal_title：Journal of medical virology

authors： Ngui SL,Granerod J,Jewes LA,Crowcroft NS,Teo CG,2002 Hepatitis A Outbreaks Investigation Network.

更新日期：2008-07-01 00:00:00

abstract：:Over the past decade, a G4P[6] strain has been found to be circulating in different neonatal wards in the Pretoria area. This endemic strain was associated with both asymptomatic and symptomatic infection, providing the opportunity to undertake a molecular study of some of the putative "virulence" genes. The genes enc...

journal_title：Journal of medical virology

authors： Pager CT,Alexander JJ,Steele AD

更新日期：2000-10-01 00:00:00

abstract：:The efficacy of interferon (IFN) monotherapy for non-responders to pegylated interferon (PEG-IFN) plus ribavirin (RBV) combination therapy is still unclear. To evaluate the impact of IFN monotherapy on biochemical response, 200 consecutive patients infected with HCV genotype 1b, who received low-dose intermittent IFN-...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Kawamura Y,Yatsuji H,Sezaki H,Suzuki Y,Hosaka T,Kobayashi M,Kobayashi M,Arase Y,Ikeda K,Kumada H

更新日期：2008-08-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) arises in up to 10% of organ transplant recipients and is fatal in ∼50% of cases. PTLD can be modeled in SCID mice using EBV+ve human B lymphoblastoid cell lines (BLCLs), and the current study investigated intraperitoneal (ip) inocu...

journal_title：Journal of medical virology

authors： Johannessen I,Bieleski L,Urquhart G,Watson SL,Wingate P,Haque T,Crawford DH

更新日期：2011-09-01 00:00:00

abstract：:Type 1 immunity appears to be diminished in healthy Japanese carriers of human T-lymphotropic virus type I (HTLV-I), but type 2 status remains undetermined. To further examine the subclinical effect of HTLV-I on host immunity, we measured serum antibodies to the Epstein-Barr virus (EBV) in 415 healthy Japanese adults ...

journal_title：Journal of medical virology

authors： Birmann BM,Mueller NE,Okayama A,Hsieh CC,Tsubouchi H,Harn D,Stuver SO

更新日期：2006-06-01 00:00:00

abstract：:The competitive ELISA test was compared with competitive RIA, complement fixation, and indirect fluorescent antibody test for the detection of antibody to varicella-zoster virus (VZV). ELISA and RIA were the most sensitive tests, being tenfold as sensitive as indirect immunofluorescence and 20 times as sensitive as co...

journal_title：Journal of medical virology

authors： Wreghitt TG,Tedder RS,Nagington J,Ferns RB

更新日期：1984-01-01 00:00:00

abstract：:Here, we studied the role of nitric oxide (NO) production during the first steps of the respiratory infection of BALB/c mice with herpes simplex virus type 1 (HSV-1), strain F. Nitric oxide synthase II (NOS-II) mRNA and protein were detected by reverse transcription (RT)-PCR and dot blot, respectively in samples of lu...

journal_title：Journal of medical virology

authors： Gamba G,Cavalieri H,Courreges MC,Massouh EJ,Benencia F

更新日期：2004-06-01 00:00:00

abstract：:Nucleotide sequences of the hypervariable region of hepatitis C virus genomes obtained from plasma change rapidly during the course of infection and are believed to play a part in immunological escape and consequently in the development of persistent infection. It is not known, however, whether these changes also occu...

journal_title：Journal of medical virology

authors： Sakamoto N,Enomoto N,Kurosaki M,Asahina Y,Maekawa S,Koizumi K,Sakuma I,Murakami T,Marumo F,Sato C

更新日期：1995-05-01 00:00:00

abstract：:There are numerous ongoing studies assessing treatment options for preventing, treating, and managing complications of coronavirus disease-2019 disease. The objective of this study was to do a systematic review and critical appraisal of the ongoing clinical trials with an aim to provide insight into the various interv...

journal_title：Journal of medical virology

authors： Venkatesulu BP,Thoguluva Chandrasekar V,Giridhar P,V P,Patel HK,Manteuffel J

更新日期：2021-02-01 00:00:00

abstract：:A viable virus could not be recovered from a mutant murine cytomegalovirus (MCMV) BAC in which the M34 ORF had been deleted (BACDeltaM34). In contrast, an M34 mutant virus (RcM34), in which the M34 ORF was interrupted by transposon insertion at nt 44,827 of the Smith MCMV BAC, was attenuated in replication both in tis...

journal_title：Journal of medical virology

authors： Baluchova K,Kirby M,Ahasan MM,Sweet C

更新日期：2008-07-01 00:00:00

abstract：:Cells from a leiomyosarcoma tumor (LMS-1) from a patient with the acquired immunodeficiency syndrome (AIDS) were explanted, cultured in vitro, and studied by phase-contrast microscopy for morphologic and growth characteristics, immunostaining for cell markers, EBER in situ hybridization and polymerase chain reaction f...

journal_title：Journal of medical virology

authors： Jenson HB,Montalvo EA,McClain KL,Ench Y,Heard P,Christy BA,Dewalt-Hagan PJ,Moyer MP

更新日期：1999-01-01 00:00:00

abstract：:Human T-lymphotropic virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is characterized by long periods of clinical latency with low levels of viral production. Transcription of HTLV-1 is controlled through sequences in the promoter and enhancer regions of the long terminal repeat of the integrated prov...

journal_title：Journal of medical virology

authors： Newbound GC,O'Rourke JP,Collins ND,Andrews JM,DeWille J,Lairmore MD

更新日期：2000-10-01 00:00:00

abstract：:Hepatitis C Virus (HCV) genotype 4 predominates in Middle East and Central Africa countries. Recently, it has become also prevalent in Southern European countries where it is thought to have been introduced through immigration and the movement of intravenous drug users. In Italy, the prevalence of genotype 4 is partic...

journal_title：Journal of medical virology

authors： Ciccozzi M,Equestre M,Costantino A,Marascio N,Quirino A,Lo Presti A,Cella E,Bruni R,Liberto MC,Focà A,Pisani G,Zehender G,Ciccaglione AR

更新日期：2012-10-01 00:00:00

abstract：:We studied epidemiologic and immunologic factors in infants with bronchiolitis caused by influenza virus. The proportion of these infants who were male and who had an immediate family member with a history of asthma was similar to that of a control group of infants with respiratory syncytial virus (RSV) bronchiolitis....

journal_title：Journal of medical virology

authors： Garofalo RP,Hintz KH,Hill V,Patti J,Ogra PL,Welliver RC Sr

更新日期：2005-02-01 00:00:00

abstract：:GII.b norovirus is an obligatory recombinant with an open reading frame (ORF) 1 comprising the GII.b genotype and the ORF 2 region corresponding to one of a number of other norovirus genotypes. GII.b is the second most common genotype after GII.4 associated with gastroenteritis outbreaks in Victoria, Australia. The st...

journal_title：Journal of medical virology

authors： Bruggink LD,Marshall JA

更新日期：2013-08-01 00:00:00

abstract：:In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the ...

journal_title：Journal of medical virology

authors： Ilyicheva T,Abdurashitov M,Durymanov A,Susloparov I,Goncharova N,Kolosova N,Mikheev V,Ryzhikov A

更新日期：2016-01-01 00:00:00

abstract：:In order to shed light on the mode of HTLV-I infection by mother-to-child transmission, we examined sera of school children in a highly endemic town on two separate occasions at a 6-year interval. The carrier rates in ages 15-17, 8.7 and 2.1%, were significantly higher than that in ages 6-8, 1.7 and 0.4%, in studies. ...

journal_title：Journal of medical virology

authors： Sugiyama H,Doi H,Yamaguchi K,Tsuji Y,Miyamoto T,Hino S

更新日期：1986-11-01 00:00:00

abstract：:A total of 190 specimens from South Indian children aged 0-59 months with ocular anomalies consistent with suspected congenital rubella syndrome (CRS) were investigated. Twenty-six of the 65 infants (40%) were confirmed as CRS by detection of rubella specific IgM. Rubella RNA was detected in 41 samples from 26 infants...

journal_title：Journal of medical virology

authors： Rajasundari TA,Sundaresan P,Vijayalakshmi P,Brown DW,Jin L

更新日期：2008-03-01 00:00:00

abstract：:Avidity maturation of IgG antibody responses directed against the structural proteins of rubella virus (E1, E2, and C) as well as whole rubella virus (RV) was assessed at sequential time intervals in 7 individuals following serologically confirmed wild rubella infection. Individual structural proteins were purified fr...

journal_title：Journal of medical virology

authors： Mauracher CA,Mitchell LA,Tingle AJ

更新日期：1992-03-01 00:00:00

abstract：:There are limited reports on the etiology of multiple enteric viruses causing acute gastroenteritis (AGE) in North India. In the present study we have determined the prevalence of three enteric viruses, namely rotavirus, astrovirus (AstV) and adenovirus (AdV) in a total of 312 diarrheic children (<5 years) hospitalize...

journal_title：Journal of medical virology

authors： Akdag AI,Gupta S,Khan N,Upadhayay A,Ray P

更新日期：2020-08-01 00:00:00