Abstract:
:Nine ducks congenitally infected with the duck hepatitis B virus (DHBV) were treated either orally (four ducks for 10 weeks) or intraperitoneally (five ducks for 12 weeks) with the Indian traditional herbal remedy Phyllanthus amarus. Compared to placebo-treated control ducks, these treatments did not result in a reduction of circulating viral DNA in the serum or in the level of viral DNA replication in the liver. In two of the five intraperitoneal-treated ducks, a reduction in the levels of duck hepatitis B surface antigenaemia (DHBsAg) was observed. The data strongly suggest that Phyllanthus amarus has no significant inhibitory effect on DHBV DNA replication and only a minor effect on DHBsAg production.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Niu JZ,Wang YY,Qiao M,Gowans E,Edwards P,Thyagarajan SP,Gust I,Locarnini Sdoi
10.1002/jmv.1890320404subject
Has Abstractpub_date
1990-12-01 00:00:00pages
212-8issue
4eissn
0146-6615issn
1096-9071journal_volume
32pub_type
杂志文章abstract::HPV infection is a "necessary cause" of cervical cancer and it is sexually transmitted. Due to upcoming mass vaccination investigation on risk factors for infection is the basis to implement prophylactic strategy even in older women. The aim of the study was to evaluate predictors of high-risk (HR) HPV infection in ad...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21887
更新日期:2010-11-01 00:00:00
abstract::The nucleotide sequence of 10 isolates of human parvovirus B19 (B19) were determined and compared throughout 96.3% of the open reading frames (4145 nucleotides from nt. 509-4653). In the 4145 nucleotides, 122 mutation sites were found, of which 24 were accompanied by amino acid displacement. Furthermore, the polymorph...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/1096-9071(200009)62:1<60::aid-jmv10>3.0.co
更新日期:2000-09-01 00:00:00
abstract::Cytomegalovirus (CMV) has been implicated in vascular pathologies and may warrant inclusion in cardiovascular predictive algorithms. We addressed this in healthy older adults and renal transplant recipients (RTR) as they retain a high burden of CMV. RTR (n = 45) stable more than 2 years after transplantation and 58 ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25697
更新日期:2020-02-04 00:00:00
abstract::The prevalence of delta agent among 120 Chinese patients with HBsAg-positive chronic active and hepatocellular carcinoma from Taiwan and Los Angeles were studied by serological assay for antibody to delta antigen and immunoperoxidase staining for delta antigen in the liver biopsies. Of 120 patients, only four with chr...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890140106
更新日期:1984-01-01 00:00:00
abstract::To determine whether unconventional pathogens causing subacute spongiform encephalopathy may be present in blood products, a newly developed hepatitis B vaccine and a widely used blood product were injected into mice and rats. As only a few aged mice in the test and the control groups showed spongiform encephalopathic...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890160103
更新日期:1985-05-01 00:00:00
abstract::The seroprevalence of hepatitis A antibodies in travellers attending London Travel Clinics increases with age and screening may eliminate the need for vaccination at present for approximately 40% of adults. The duration of protection by current hepatitis A vaccine(s) is still to be established. ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890440414
更新日期:1994-12-01 00:00:00
abstract::Although risk factors for cirrhosis in chronic hepatitis C virus (HCV) infection have been identified, the role of HCV-genotype 3 remains controversial, and limited data are available in drug users. The aim of the study was to assess risk factors for severe liver disease (cirrhosis/hepatocellular carcinoma) in HCV-inf...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21850
更新日期:2010-10-01 00:00:00
abstract::Despite prolonged undetectable plasma viral load some HIV-1 infected patients have been reported to develop resistance-associated mutations leading to treatment failure. The mechanisms for this phenomenon and the point of origin for residual viral evolution are still not elucidated. In order to quantify cell-associate...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20993
更新日期:2007-10-01 00:00:00
abstract::Because in situ/filter hybridisation is not sensitive enough and because classical polymerase chain reaction (PCR) protocols are generally not sufficiently reproducible and specific, there is little accurate information on the prevalence of human papillomaviruses (HPV) 16, 18, and 33 infections in women without dyskar...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890360409
更新日期:1992-04-01 00:00:00
abstract:BACKGROUND:Seasonal influenza is an annual occurrence that leads to large community outbreaks and increased hospitalisation. A number of studies have suggested that influenza A (FLUAV) is associated with increased rates of hospitalisation and mortality compared to influenza B (FLUBV). This study compared demographic an...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26600
更新日期:2020-10-15 00:00:00
abstract::Currently, data examining nationally representative prevalence and trends of HBV or HCV among specific subgroups of pregnant women in the US are unavailable. We conducted a cross-sectional analysis of hospitalizations for liveborn singleton deliveries from 1998 to 2011 using data from the Nationwide Inpatient Sample. ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24725
更新日期:2017-06-01 00:00:00
abstract::The JC virus (JCV) is a common human virus persisting in renal tissue. In immunocompromised individuals it may reactivate and cause progressive multifocal leukoencephalopathy (PML). JCV has also been implicated in cancerogenesis, leading to various brain tumors and cancers of gastrointestinal tract. In this study the ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21153
更新日期:2008-06-01 00:00:00
abstract::Rotavirus infection is associated both in vivo and in vitro with a series of subcellular pathological alterations leading to cell lysis. It has been suggested that these modifications can play a key role in the pathogenesis of rotavirus-associated diarrheal disease. We describe the effects of SA-11 rotavirus infection...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9071(199612)50:4<325::AID-JMV8>
更新日期:1996-12-01 00:00:00
abstract::Epstein-Barr virus (EBV) DNA load in the blood increases in posttransplant lymphoproliferative disorders and chronic active EBV infection. In this report, we analyzed the EBV DNA load in the peripheral blood mononuclear cells (PBMCs) and plasma of patients with hydroa vacciniforme (HV) and/or hypersensitivity to mosqu...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25811
更新日期:2020-04-07 00:00:00
abstract::A healthy patient presented to Klinikum Altmühlfranken Weißenburg Hospital, Germany, with two morning attacks of painful muscle spasm in the left upper and lower limbs, without altered consciousness. Full examinations, radiological imaging, electroencephalography, lumbar puncture, and autoimmune profile were either no...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26113
更新日期:2020-10-01 00:00:00
abstract::This study aimed to examine the baseline prevalence of genital human papillomavirus (HPV) infection among human immunodeficiency virus (HIV)-seropositive men who have sex with men in Taiwan and to determine the association of age and CD4+ T cell counts with HPV infection. In 2010, 305 men who have sex with men infecte...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23413
更新日期:2012-12-01 00:00:00
abstract::Herpes simplex virus (HSV)-specific IgG and IgA antibody response in patients with HSV infection and in healthy adults was studied by the immunoperoxidase antibody-membrane antigen (IPAMA) technique. In all HSV infections in which specific IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA), a si...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890140303
更新日期:1984-01-01 00:00:00
abstract::Neutralization of virus is likely to be necessary for development of an effective prophylactic vaccine against genital human papillomavirus (HPV) infection. Two New Zealand white rabbits were immunized with purified HPV type 11 (HPV 11) virions in Freund's adjuvant. An enzyme linked immunoassay (ELISA) was used to det...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199711)53:3<185::aid-jmv1>
更新日期:1997-11-01 00:00:00
abstract::To report the clinical characteristics and potential risk factors of patients with coronavirus disease 2019 (COVID-19) in Wuhan Stadium Cabin Hospital in Hubei Province. A total of 571 patients of COVID-19 treated in the Wuhan Stadium Cabin Hospital were selected for analysis, univariable and multivariable logistic re...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26414
更新日期:2021-02-01 00:00:00
abstract::Persisting human papillomavirus (HPV) infection is a critical step in cervical carcinogenesis. This study was conducted to determine the type-specific HPV persistence and risk factors for persistence of high-risk HPV infections in a large cohort of Danish women. The study was based on a population-based prospective co...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21750
更新日期:2010-04-01 00:00:00
abstract::There are contradictory reports regarding the effects of inhalation anesthetics on the immune system. Measurable immune responses have been studied in vitro, but little is known about the in vivo effects in the intact organism. We used an attenuated, non-neuroinvasive, nonlethal strain of the encephalitic West Nile vi...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.2184
更新日期:2002-04-01 00:00:00
abstract::GB virus C/hepatitis G virus (GBV-C/HGV) RNA was detected by reverse transcription-polymer- ase chain reaction with primers derived from the nonstructural region 3 (NS3) in 9 (4.1%) of 221 blood donors and 2 of 20 (10%) hemophilia patients in Martinique, French West Indies. Anti-E2 antibodies were found in sera from 3...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1999-10-01 00:00:00
abstract::The use of quantitative assays for hepatitis C virus specific antibodies (anti-HCV) as a prognostic marker was evaluated in 31 patients with chronic hepatitis C treated with interferon (IFN). Changes in titers of serum HCV-RNA and anti-HCV antibodies; anti-C11 (anti-core), anti-C100 (anti-NS3), and anti-C7 (anti-NS3) ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890420405
更新日期:1994-04-01 00:00:00
abstract::The 70 kDa heat shock protein (Hsp70) is generally considered to be an intracellular protein, however, there is evidence that Hsp70 can be found in the extracellular environment. Hsp70 and antibodies against Hsp70 have been reported in human serum. Recent evidence has shown that Hsp70 antibodies are elevated in HIV in...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20384
更新日期:2005-08-01 00:00:00
abstract::A solution of pooled cryo-precipitate for preparing factor VIII (F VIII) by the solvent/detergent method was contaminated experimentally with parvovirus B19-positive plasma to evaluate virus reduction achieved by the final steps of the F VIII production process. Virus reduction was at least 2 logs of the total amount ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890350107
更新日期:1991-09-01 00:00:00
abstract::We compared characteristics of patients with GB virus C/hepatitis G virus (GBV-C/HGV) RNA to those of patients with GBV-C/HGV E2-antibody. GBV-C/HGV RNA and GBV-C/HGV antibody were assayed in 83 persons with hemophilia using a reverse transcription-polymerase chain reaction and an enzyme-linked immunosorbent assay, re...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(200001)60:1<34::aid-jmv6>3
更新日期:2000-01-01 00:00:00
abstract::N-Acetylethyleneimine (AEI) was used to inactivate the avirulent Togavirus Semliki Forest virus (A774 strain) grown in chick embryo, Vero, and brain cell cultures. The purity of the virus preparation affected the kinetics of inactivation. The rate of inactivation increased with a rise in temperature from 5 to 40 degre...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890190409
更新日期:1986-08-01 00:00:00
abstract::The effect of different formulations of interferon on therapeutic response in patients coinfected with HIV and HCV is unclear. In this study, the safety, tolerability, viral kinetics (VK) modeling and host responses among HIV/HCV coinfected patients treated with pegylated-IFN or albinterferon alfa-2b (AlbIFN) with wei...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23773
更新日期:2014-02-01 00:00:00
abstract::Oncogenic human papillomavirus (HPV), a causative agent of uterine cervical cancer, has also been detected in head and neck squamous cell cancers, especially in squamous cell carcinomas of the tonsils. However, the true HPV prevalence in normal and neoplasic oropharyngeal mucosa remains uncertain. To determine the pre...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20583
更新日期:2006-05-01 00:00:00
abstract::We studied the role of sexual transmission in the epidemiology of HCV by a cross-sectional study comparing prostitutes and HCV seropositive and seronegative sexual clients recruited from the bordellos of the docks of Santos, São Paulo State. The average age in the prostitute group was 27.2 years. The median time spent...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00