Abstract:
:Herpes simplex virus (HSV)-specific IgG and IgA antibody response in patients with HSV infection and in healthy adults was studied by the immunoperoxidase antibody-membrane antigen (IPAMA) technique. In all HSV infections in which specific IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA), a significant rise in the titer of HSV IgG and IgA antibodies was found. In contrast, in patients with recurrent herpes labialis in which no specific HSV IgM antibodies were detected by ELISA, HSV IgG and IgA antibodies were not found to fluctuate significantly during the course of infection. A higher geometric mean titer (GMT) for HSV IgG and for IgA antibodies was found in seropositive individuals with a previous history of recurrent HSV than in seropositive individuals without a previous history of recurrent HSV infection. Nineteen of 26 HSV IgG seropositive healthy medical students without a previous history of recurrent HSV infection had HSV IgA antibodies to membrane antigen. The significance of this finding in understanding the mechanism of latency in healthy seropositive individuals without previous history of HSV recurrent infections is discussed.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Hadar T,Sarov Idoi
10.1002/jmv.1890140303subject
Has Abstractpub_date
1984-01-01 00:00:00pages
201-7issue
3eissn
0146-6615issn
1096-9071journal_volume
14pub_type
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journal_title:Journal of medical virology
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更新日期:2020-08-01 00:00:00
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更新日期:2014-09-01 00:00:00
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更新日期:2018-04-01 00:00:00
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更新日期:2009-11-01 00:00:00
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更新日期:2008-03-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890100208
更新日期:1982-01-01 00:00:00
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更新日期:1996-06-01 00:00:00
abstract::Several studies have indicated that viral reactivations following allogeneic hematopoietic stem cell transplantation (allo-HSCT) are frequent, but viral reactivations after autologous HSCT (auto-HSCT) have not been investigated in detail. We performed multiplex polymerase chain reaction (PCR) assay to examine multiple...
journal_title:Journal of medical virology
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更新日期:2017-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/jmv.20561
更新日期:2006-04-01 00:00:00
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doi:10.1002/jmv.25607
更新日期:2020-03-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::Flow cytometric analysis of CD4(+) and CD8(+) T cells specific to human cytomegalovirus (CMV) was undertaken in seven patients with congenital CMV infection, six healthy infants who had acquired infection, and six CMV-seropositive adults. Intracellular cytokine assays showed that 0.03-2.23% of CD4(+) T cells in the he...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10477
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Human metapneumovirus (hMPV) is a recently detected virus, which can cause mild to severe respiratory tract infections. Through this study, we aimed to detail the outcomes of hMPV infections. MATERIALS/METHODS:Between January 2012 and November 2017, patients who had hMPV detected in nasopharyngeal or bronch...
journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00
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更新日期:1992-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-05-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章,随机对照试验
doi:10.1002/jmv.23297
更新日期:2012-06-01 00:00:00
abstract::It has been reported that low-plasma cytomegalovirus (CMV) DNA loads are associated with an increased risk of overall mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Utilizing a conservative strategy for initiation of preemptive antiviral therapy (>1500 IU/mL), we characterized the virolog...
journal_title:Journal of medical virology
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更新日期:2019-06-01 00:00:00
abstract::Paired serum and saliva samples were tested by enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) for the presence of human immunodeficiency virus (HIV) antibodies. The study group included 36 individuals known to be HIV seropositive and 14 healthy, seronegative controls. HIV antibodies were detected in a...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890300403
更新日期:1990-04-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24280
更新日期:2015-12-01 00:00:00
abstract::The plaque reduction neutralization test (PRNT) has been used routinely in serological studies with such arenaviruses as Junin, Machupo, and Parana. However, difficulties have been encountered in using the PRNT for LCM virus, while conflicting views have been expressed about the reliability and efficacy of the test wi...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890220110
更新日期:1987-05-01 00:00:00
abstract::Taiwan was a hyperendemic area for hepatitis A and B viruses (HAV and HBV) infection before late 1980s. To study the seroprevalence of hepatitis A, B, C, and E viruses (HCV and HEV) infection among preschool children in Taiwan, a community-based survey was carried out in 54 kindergartens in 10 urban areas, 10 rural ar...
journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890460103
更新日期:1995-05-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-09-01 00:00:00
abstract::Strains of human coronavirus (HCV) isolated between 1974 and 1976 have been studied in vitro and in volunteers. All strains caused colds in volunteers, and those cultivable in tissue culture (TC) produced significantly more coryza and less sore throat than strains growing only in organ culture (OC). The TC strains wer...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890130208
更新日期:1984-01-01 00:00:00