The behaviour of recent isolates of human respiratory coronavirus in vitro and in volunteers: evidence of heterogeneity among 229E-related strains.

abstract：:Present diagnostic criteria for occult hepatitis B virus (HBV) infection requires blood or liver samples to test positive for at least two HBV DNA targets in hepatitis B surface antigen (HBsAg) negative individuals. These criteria were derived from studies involving referred or selected patient populations. The object...

journal_title：Journal of medical virology

authors： Minuk GY,Huynh C,Uhanova J,Osiowy C

更新日期：2014-01-01 00:00:00

abstract：:Adhesion molecules are essential for the immune response. They are involved in the regulation of cell-to-cell contact, thereby enabling leukocytes to communicate. Circulating forms of adhesion molecules are found in the serum of healthy individuals. Raised levels have been associated with disease severity in HCV and o...

journal_title：Journal of medical virology

authors： Murgue B,Cassar O,Deparis X

更新日期：2001-09-01 00:00:00

abstract：:Noroviruses (called formerly "Norwalk-like viruses") cause food-borne gastroenteritis outbreaks. These outbreaks were thought to be related to shellfish consumption, although non-shellfish related outbreaks also occurred frequently in Japan. To clarify the epidemiology of Norovirus outbreaks, 435 stool samples were co...

journal_title：Journal of medical virology

authors： Hamano M,Kuzuya M,Fujii R,Ogura H,Yamada M

更新日期：2005-10-01 00:00:00

abstract：:The prevalence of delta agent among 120 Chinese patients with HBsAg-positive chronic active and hepatocellular carcinoma from Taiwan and Los Angeles were studied by serological assay for antibody to delta antigen and immunoperoxidase staining for delta antigen in the liver biopsies. Of 120 patients, only four with chr...

journal_title：Journal of medical virology

authors： Govindarajan S,Lee SD,Tong MJ,Tsai YT,Lo KJ

更新日期：1984-01-01 00:00:00

abstract：:Persisting human papillomavirus (HPV) infection is a critical step in cervical carcinogenesis. This study was conducted to determine the type-specific HPV persistence and risk factors for persistence of high-risk HPV infections in a large cohort of Danish women. The study was based on a population-based prospective co...

journal_title：Journal of medical virology

authors： Nielsen A,Kjaer SK,Munk C,Osler M,Iftner T

更新日期：2010-04-01 00:00:00

abstract：:Although risk factors for cirrhosis in chronic hepatitis C virus (HCV) infection have been identified, the role of HCV-genotype 3 remains controversial, and limited data are available in drug users. The aim of the study was to assess risk factors for severe liver disease (cirrhosis/hepatocellular carcinoma) in HCV-inf...

journal_title：Journal of medical virology

authors： Larsen C,Bousquet V,Delarocque-Astagneau E,Pioche C,Roudot-Thoraval F,HCV Surveillance Steering Committee.,HCV Surveillance Group.,Desenclos JC

更新日期：2010-10-01 00:00:00

abstract：:To report the clinical characteristics and potential risk factors of patients with coronavirus disease 2019 (COVID-19) in Wuhan Stadium Cabin Hospital in Hubei Province. A total of 571 patients of COVID-19 treated in the Wuhan Stadium Cabin Hospital were selected for analysis, univariable and multivariable logistic re...

journal_title：Journal of medical virology

authors： Shu L,Wang X,Li M,Chen X,Ji N,Shi L,Wu M,Deng K,Wei J,Wang X,Cao Y,Yan J,Feng G

更新日期：2021-02-01 00:00:00

abstract：:Physicochemical studies of hepatitis B e antigen (HBeAg) revealed a clear cut difference between e1 and e2 antigen. The e1 antigen was found to have a MW of Ca 150,000 and a pI of 6.4-7.2, whereas both the MW and pI of the e2 antigen were heterogeneous depending upon the source of serum. Sera obtained from asymptomati...

journal_title：Journal of medical virology

authors： Yamada E,Ohori H,Ishida N

更新日期：1979-01-01 00:00:00

abstract：:Annual outbreaks of seasonal influenza cause a substantial health burden. The aim of this study was to compare patient demographic/clinical data in two influenza patient groups presenting to hospital; those requiring O2 or critical care admission and those requiring less intensive treatment. The study was conducted fr...

journal_title：Journal of medical virology

authors： Dominic C,Welch C,Melzer M

更新日期：2020-07-31 00:00:00

abstract：:Ideally, long-term lamivudine therapy should not induce tyrosine-methionine-aspartate-aspartate (YMDD) mutants (reverse transcription [rt]; rt M204I/V) in patients with chronic hepatitis B. There is little or no information on the clinical features of patients who do not develop such mutants. We analyzed 368 patients ...

journal_title：Journal of medical virology

authors： Hashimoto Y,Suzuki F,Hirakawa M,Kawamura Y,Yatsuji H,Sezaki H,Hosaka T,Akuta N,Kobayashi M,Saito S,Suzuki Y,Kobayashi M,Arase Y,Ikeda K,Kumada H

更新日期：2010-04-01 00:00:00

abstract：:There are limited reports on the etiology of multiple enteric viruses causing acute gastroenteritis (AGE) in North India. In the present study we have determined the prevalence of three enteric viruses, namely rotavirus, astrovirus (AstV) and adenovirus (AdV) in a total of 312 diarrheic children (<5 years) hospitalize...

journal_title：Journal of medical virology

authors： Akdag AI,Gupta S,Khan N,Upadhayay A,Ray P

更新日期：2020-08-01 00:00:00

abstract：:False negativity in a commercial anti-HIV kit (IMx HIV-1/HIV-2 3rd Generation Plus (code 8B32) was investigated, and the kit that superseded it (IMx HIV-1/HIV-2 III Plus, code 8C98) was evaluated. In a comparison on 574 freshly collected anti-HIV-1-positive specimens, 97.2% were more reactive in 8C98 than in 8B32; 35....

journal_title：Journal of medical virology

authors： Parry JV,Perry KR,Harbour S,Burgess C,Mortimer PP,Blackburn NK,Martin D

更新日期：1998-10-01 00:00:00

abstract：:The various strains of human polyomavirus BK (BKV) show a marked heterogeneity in the non-coding control region (NCCR), which includes the origin of replication and the regulatory region for early and late transcription. A new BKV strain (DDP, U91605) was identified by direct detection and sequencing of PCR products o...

journal_title：Journal of medical virology

authors： Degener AM,Pietropaolo V,Di Taranto C,Jin L,Ameglio F,Cordiali-Fei P,Trento E,Sinibaldi L,Orsi N

更新日期：1999-08-01 00:00:00

abstract：:Saffold viruses (SAFV) have been discovered recently and they are classified into Theilovirus species in genus Cardiovirus in the Picornaviridae family. SAFV, especially those belonging to the genotype 2, have been difficult to propagate in laboratory cell lines. This study describes the successful isolation of an eff...

journal_title：Journal of medical virology

authors： Blomqvist S,Lappalainen M,Paananen A,Ylipaasto P,Roivainen M

更新日期：2012-09-01 00:00:00

abstract：:Immunoglobulin class-specific determination by ELISA and a virus neutralization test (NT) were compared for the detection of the serum antibody responses after vaccination of infants with the RIT 4237 rotavirus vaccine (of bovine origin). A capture method was applied for specific IgM determination by ELISA because of ...

journal_title：Journal of medical virology

authors： Delem A,Vesikari T

更新日期：1987-03-01 00:00:00

abstract：:Human parainfluenza virus 3 (HPIV-3) is a leading cause of respiratory disease in children worldwide. Previous sequence analyses of the entire virus genome, among different HPIV-3 strains, demonstrated that HN is the most variable gene. There is a dearth of data on HPIV-3 strains circulating in Saudi Arabia. In this r...

journal_title：Journal of medical virology

authors： Almajhdi FN,Alshaman MS,Amer HM

更新日期：2012-08-01 00:00:00

abstract：:Sera from patients with sandfly fever caused by Toscana virus (TOSV) infection were tested by immunoblot for specific antibody response to TOSV derived from infected Vero-E6 cells. The 28 kDa TOSV nucleoprotein (N) was identified as the major immunodominant protein recognized by immunoblot. In sera of patients with ac...

journal_title：Journal of medical virology

authors： Schwarz TF,Gilch S,Pauli C,Jäger G

更新日期：1996-06-01 00:00:00

abstract：:Lack of recognition of human immunodeficiency virus (HIV) infection especially in children and delayed implementation of effective control programs makes HIV infection as a major cause for concern. Information on HIV epidemiology in Iran as well as other Islamic countries is limited. The aim of our study was to descri...

journal_title：Journal of medical virology

authors： Movahedi Z,Mahmoudi S,Pourakbari B,Keshavarz Valian N,Sabouni F,Ramezani A,Bahador A,Mamishi S

更新日期：2016-01-01 00:00:00

abstract：:The replication strategy of a human serotype 1 rotavirus, adapted to rapid growth in CV-1 cells, was investigated. A single cycle growth curve revealed eclipse and latent periods of 3 and 4 hours, respectively. Although the extent of reduction of host cell protein synthesis was directly related to the multiplicity of ...

journal_title：Journal of medical virology

authors： Heath RL,Birch CJ

更新日期：1988-05-01 00:00:00

abstract：:During the 1976 Ebola virus outbreak in Sudan, the investigations team gained the impression that fewer haemorrhagic manifestations and few fatalities occurred during the later stages of the epidemic after the virus had undergone several generations in man. This impression was also noted in guinea pigs experimentally ...

journal_title：Journal of medical virology

authors： Bowen ET,Platt GS,Lloyd G,Raymond RT,Simpson DI

更新日期：1980-01-01 00:00:00

abstract：:It is need for development of new means against influenza virus due to the lack of efficacy of available therapeutic strategies. In previous research, 1,8-cineol exert its inhibition of nuclear factor (NF)-κB, the main regulator of cytokine and chemokine production in influenza, and anti-inflammatory activity. These f...

journal_title：Journal of medical virology

authors： Lai YN,Li Y,Fu LC,Zhao F,Liu N,Zhang FX,Xu PP

更新日期：2017-07-01 00:00:00

abstract：:Here, we studied the role of nitric oxide (NO) production during the first steps of the respiratory infection of BALB/c mice with herpes simplex virus type 1 (HSV-1), strain F. Nitric oxide synthase II (NOS-II) mRNA and protein were detected by reverse transcription (RT)-PCR and dot blot, respectively in samples of lu...

journal_title：Journal of medical virology

authors： Gamba G,Cavalieri H,Courreges MC,Massouh EJ,Benencia F

更新日期：2004-06-01 00:00:00

abstract：:Lentiviral vectors are prime candidate vectors for gene transfer into dividing and non-dividing cells, including neuronal cells and stem cells. For safety, HIV-2 lentiviral vectors may be better suited for gene transfer in humans than HIV-1 lentiviral vectors. HIV-2 vectors cross-packaged in HIV-1 cores may be even sa...

journal_title：Journal of medical virology

authors： D'Costa J,Harvey-White J,Qasba P,Limaye A,Kaneski CR,Davis-Warren A,Brady RO,Bankiewicz KS,Major EO,Arya SK

更新日期：2003-10-01 00:00:00

abstract：:Epstein-Barr virus (EBV) reactivation and cell-mediated immune (CMI) responses were followed in 16 Antarctic expeditioners during winter-over isolation at 2 Australian National Antarctic Research Expedition stations. Delayed-type hypersensitivity (DTH) skin testing was used as an indicator of the CMI response, that wa...

journal_title：Journal of medical virology

authors： Mehta SK,Pierson DL,Cooley H,Dubow R,Lugg D

更新日期：2000-06-01 00:00:00

abstract：:Dried blood spots collected on filter paper are considered potential clinical specimens for measles surveillance because of their ease of collection, storage, and transport. The usefulness of these samples for surveillance of measles was evaluated in a field setting. Blood spots were collected by finger-prick from 316...

journal_title：Journal of medical virology

authors： El Mubarak HS,Yüksel S,Mustafa OM,Ibrahim SA,Osterhaus AD,de Swart RL

更新日期：2004-08-01 00:00:00

abstract：:In vitro incubation of human cytomegalovirus (Towne strain) with 8 U/ml human recombinant myeloperoxidase plus sodium chloride and glucose nearly abolished viral infectivity. To assay the effect on intracellular infection, cell toxicity of the enzymes was first studied. Even the high dose of 16 U/ml of recombinant mye...

journal_title：Journal of medical virology

authors： El Messaoudi K,Verheyden AM,Thiry L,Fourez S,Tasiaux N,Bollen A,Moguilevsky N

更新日期：2002-02-01 00:00:00

abstract：:Hemagglutination inhibition (HI), single radial hemolysis (SRH) and enzyme-linked immuno sorbent assay (ELISA), performed with commercial antigen and reagents are described and were compared in the three distinct situations that require rubella antibody detection. Determination of immunity status was carried out on 15...

journal_title：Journal of medical virology

authors： Champsaur H,Dussaix E,Tournier P

更新日期：1980-01-01 00:00:00

abstract：:The influence of an acute Epstein-Barr virus (EBV) infection on the serological parameters of persistent varicella-zoster virus (VZV) and herpes simplex virus (HSV) was studied. Sera from 161 patients with infectious mononucleosis caused by EBV and 178 age-matched controls were tested for HSV- and VZV-specific IgA. 98...

journal_title：Journal of medical virology

authors： Karner W,Bauer G

更新日期：1994-11-01 00:00:00

abstract：:The ability of the total hepatitis C virus (HCV) core antigen assay was evaluated for monitoring the therapeutic responses of HCV-infected patients treated with interferon. The ability to detect and quantitate an independent structural protein component of HCV, in the presence of circulating antibodies, makes this ass...

journal_title：Journal of medical virology

authors： Zanetti AR,Romanò L,Brunetto M,Colombo M,Bellati G,Tackney C

更新日期：2003-05-01 00:00:00

abstract：:The L1 gene encodes for the major capsid protein of human papillomaviruses (HPV). There is limited information on the polymorphism of L1 for types related to HPV-16. This report explores the polymorphism of L1 in phylogenetically related types 31, 33, and 35 compared to HPV-16. Genital specimens collected from 732 HIV...

journal_title：Journal of medical virology

authors： Cornut G,Gagnon S,Hankins C,Money D,Pourreaux K,Franco EL,Coutlée F,Canadian Women's HIV Study Group.

更新日期：2010-07-01 00:00:00