Synthesis of human rotavirus polypeptides in cell culture.

abstract：:Attachment of hepatitis B virus to a hepatoblastoma cell line (HepG2) was examined using a synthetic peptide corresponding to the pre-S1 (21-47) region of the envelope protein. Scatchard analysis revealed a single class binding site of Kd 104 +/- 27 nM/l and 5.4 +/- 1.2 x 10(5) sites per cell. Competition of HBV with ...

journal_title：Journal of medical virology

authors： Dash S,Rao KV,Panda SK

更新日期：1992-06-01 00:00:00

abstract：:Vaccine effectiveness may wane with increasing time since vaccination. This analysis used the Victorian sentinel general practitioner (GP) network to estimate vaccine effectiveness for trivalent inactivated vaccines in the 2012 season. A test-negative design was used where patients presenting to GPs with influenza-lik...

journal_title：Journal of medical virology

authors： Sullivan SG,Komadina N,Grant K,Jelley L,Papadakis G,Kelly H

更新日期：2014-06-01 00:00:00

abstract：:Although analytical treatment interruption is used as a strategy to test immunotherapeutic agents in HIV-infection, it may pose a risk for study participants. The potential risks of short-term interruption of antiretroviral therapy (ART) during treatment with an autologous dendritic cell immune-based therapy (AGS-004-...

journal_title：Journal of medical virology

authors： Routy JP,Boulassel MR,Nicolette CA,Jacobson JM

更新日期：2012-06-01 00:00:00

abstract：:A sensitive and reproducible real-time PCR assay based on TaqMan technology was developed for the detection and quantitation of hepatitis B virus (HBV) DNA in serum, and compared with an "in-house" qualitative PCR assay. HBV DNA was measured in 125 serum samples from 76 hepatitis B patients, consisting of 22 patients ...

journal_title：Journal of medical virology

authors： Chen RW,Piiparinen H,Seppänen M,Koskela P,Sarna S,Lappalainen M

更新日期：2001-10-01 00:00:00

abstract：:Studies have shown that swine HEV (sHEV) and rabbit HEV (rHEV) can experimentally infect rabbits and swine, respectively. However, no published data have documented isolating sHEV strains from rabbits in natural environment so far. To clarify the possibility of natural cross-species transmission of sHEV to rabbits, th...

journal_title：Journal of medical virology

authors： Liu L,Wang L,Xia J,Zhang Y,Zeng H,Liu P,Zou Q,Wang L,Zhuang H

更新日期：2016-04-01 00:00:00

abstract：:Rapid PCR-based influenza tests are increasingly used as point-of-care diagnostics in hospitals and clinics. To our knowledge, no prior studies have described clinical outcomes with implementation of rapid PCR-based influenza tests in hospitalized adult inpatients. Electronic medical records were used to assess differ...

journal_title：Journal of medical virology

authors： Chu HY,Englund JA,Huang D,Scott E,Chan JD,Jain R,Pottinger PS,Lynch JB,Dellit TH,Jerome KR,Kuypers J

更新日期：2015-12-01 00:00:00

abstract：:The JC virus (JCV) is a common human virus persisting in renal tissue. In immunocompromised individuals it may reactivate and cause progressive multifocal leukoencephalopathy (PML). JCV has also been implicated in cancerogenesis, leading to various brain tumors and cancers of gastrointestinal tract. In this study the ...

journal_title：Journal of medical virology

authors： Kmieciak D,Debicki S,Trzeciak WH

更新日期：2008-06-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML), a viral-induced demyelinating disease, is becoming relatively common, while many diagnostic and pathogenetic aspects remain to be clarified. A study was therefore undertaken in 64 AIDS patients suffering from various neurological disorders, including PML (12 subjects),...

journal_title：Journal of medical virology

authors： Ferrante P,Caldarelli-Stefano R,Omodeo-Zorini E,Cagni AE,Cocchi L,Suter F,Maserati R

更新日期：1997-07-01 00:00:00

abstract：:The resurgence of Chikungunya virus (CHIKV) in the form of unprecedented and explosive epidemics in India and the Indian Ocean islands after a gap of 32 years is a major public health concern. Currently, there is no specific therapy available to treat CHIKV infection. In the present study, the in vitro prophylactic an...

journal_title：Journal of medical virology

authors： Khan M,Santhosh SR,Tiwari M,Lakshmana Rao PV,Parida M

更新日期：2010-05-01 00:00:00

abstract：:Limited data are available describing human papillomavirus (HPV) genotype distribution among females with cytological abnormalities in Switzerland. Cervical cell specimens obtained from 5,318 women were screened routinely by liquid-based Pap smear. All specimens with cellular abnormalities were analyzed subsequently f...

journal_title：Journal of medical virology

authors： Dobec M,Bannwart F,Kilgus S,Kaeppeli F,Cassinotti P

更新日期：2011-08-01 00:00:00

abstract：:Multiple determinants are involved in the progression of human papillomavirus (HPV)-infected cervical lesion to invasive cancer. Human leukocyte antigen (HLA) polymorphism seems to play a role. This study examined the association between HLA-DRB1 polymorphism, high-risk HPV infection, and the development of cervical n...

journal_title：Journal of medical virology

authors： Chan PK,Cheung TH,Lin CK,Siu SS,Yim SF,Lo KW,Cheung JL,Tam AO,Tang JW

更新日期：2007-07-01 00:00:00

abstract：:Comparison of RT-PCR assays established in house at various places revealed that laboratories could differ in sensitivity by as much as 1,000-fold in terms of the ability to detect measles virus sequences in clinical samples. The study indicates that PCR findings, positive or negative, are questionable if they are not...

journal_title：Journal of medical virology

authors： Afzal MA,Osterhaus AD,Cosby SL,Jin L,Beeler J,Takeuchi K,Kawashima H

更新日期：2003-05-01 00:00:00

abstract：:An outbreak of dengue type 2 occurred in North Queensland, Australia, between December 1996 and April 1997. Culture of serum in the Aedes albopictus C6/36 cell line with detection using immunofluorescent staining was compared with a culture-amplified detection system using an immunoperoxidase staining method in a micr...

journal_title：Journal of medical virology

authors： Gleeson F,McBride J,Norton R

更新日期：1999-02-01 00:00:00

abstract：:Human herpes virus 8 (HHV 8) is recognized as the necessary cause of Kaposi sarcoma (KS) and in the recent past the human papillomavirus (HPV) has been linked to the development of cutaneous basal cell and squamous cell carcinomas. In a cross sectional study investigating Beta-HPV infections in skin lesions, an unexpe...

journal_title：Journal of medical virology

authors： Murahwa AT,Muchemwa FC,Duri K,Borok MZ,Kanyera RB,Manhanzva MT,Mapingure MP,Stray-Pedersen B

更新日期：2014-09-01 00:00:00

abstract：:From the Pacific Republic of Kiribati, 90/130 (69%) of hepatitis B-infected individuals carry antibodies to hepatitis delta virus. The prevalence of delta infection varied between geographically isolated subgroups in the population and delta antibodies were found more frequently in subjects over the age of 10. It is u...

journal_title：Journal of medical virology

authors： Tibbs CJ

更新日期：1989-10-01 00:00:00

abstract：:The effect on cellular (c) oncogene RNA levels was investigated after infection of permissive cells with cell culture adapted strains (AD-169, C-87, Davis) and unadapted clinical isolates (82-1, 84-2, 85-1) of human cytomegalovirus (HCMV). The results indicate that both adapted and unadapted strains of HCMV induce sub...

journal_title：Journal of medical virology

authors： Boldogh I,AbuBakar S,Fons MP,Deng CZ,Albrecht T

更新日期：1991-08-01 00:00:00

abstract：:Hepatitis B virus (HBV) genotypes impact treatment outcomes and disease progression. The current genotyping methods have limitations in patients with low HBV viral load. In this study, a more sensitive assay has been developed for determining the HBV genotype in HBV DNA suppressed patients. Fifty-five serum samples fr...

journal_title：Journal of medical virology

authors： Liu Y,May L,Liu X,Martin R,Svarovskaia E,Gaggar A,Mo H,Feierbach B

更新日期：2020-07-01 00:00:00

abstract：:The 30-base pair (bp) deletion of the cytoplasmic carboxy-terminal domain of the latent membrane protein 1 (LMP-1) gene was analyzed in 37 frozen tissues from patients with Epstein-Barr virus (EBV)-related gastric cancer and 18 throat washings from healthy adults in southern Japan. The 30-bp deletion was identified in...

journal_title：Journal of medical virology

authors： Mori S,Itoh T,Tokunaga M,Eizuru Y

更新日期：1999-02-01 00:00:00

abstract：:No controlled trial in patients with chronic hepatitis B virus (HBV) infection on long-term entecavir (ETV) treatment, comparing switching to tenofovir disoproxil fumarate (TDF) with continuing the therapy, has been reported. Twenty-seven nucleos(t)ide-naïve patients with chronic HBV who underwent ETV therapy for ≥5 y...

journal_title：Journal of medical virology

authors： Iida-Ueno A,Enomoto M,Kozuka R,Tamori A,Kawada N

更新日期：2019-07-01 00:00:00

abstract：:Latency associated peptide (LAP) is a protein expressed on the membrane of some regulatory T cells (Treg). LAP+ Treg have a greater immunomodulatory effect than that of their negative counterparts. In this study, we presented the data on the proportion of LAP+ Treg out of CD4+ cells in mice with viral myocarditis, whi...

journal_title：Journal of medical virology

authors： Wang X,Ge J,Chen R

更新日期：2019-05-01 00:00:00

abstract：:Acute hepatitis B virus (HBV) infection was diagnosed in 57 adults admitted to Toranomon Hospital in Tokyo, Japan. Genotypes of HBV were determined by a serological method and compared to those in 1,077 patients with chronic hepatitis B. The distribution of genotypes were: genotype A (acute, 22.8% vs. chronic, 1.9%; P...

journal_title：Journal of medical virology

authors： Kobayashi M,Arase Y,Ikeda K,Tsubota A,Suzuki Y,Saitoh S,Kobayashi M,Suzuki F,Akuta N,Someya T,Matsuda M,Sato J,Takagi K,Miyakawa Y,Kumada H

更新日期：2002-12-01 00:00:00

abstract：:Distinct human papillomavirus (HPV) 18 variants are thought to differ in oncogenic potential and geographic distribution. As such, understanding the regional variants of HPV 18 would be of great importance for evolutionary, epidemiological, and biological analysis. In this regard, the sequence variations of E6 gene we...

journal_title：Journal of medical virology

authors： Salavatiha Z,Shoja Z,Heydari N,Marashi SM,Younesi S,Nozarian Z,Jalilvand S

更新日期：2020-07-09 00:00:00

abstract：:According to the Joint National Programme on HIV/AIDS (UNAIDS), the northeastern region of India has the highest HIV prevalence in the country. This study was conducted to determine the current HIV-1 molecular epidemiology of Manipur, a state in northeast India. Blood samples from HIV-1 seropositive subjects were coll...

journal_title：Journal of medical virology

authors： Sharma AL,Singh TR,Devi KR,Singh LS

更新日期：2017-06-01 00:00:00

abstract：:Although a T-cell response in human cytomegalovirus (HCMV)-immune individuals exists against the most abundantly expressed protein pp65 of the virus matrix, less is known about the determinants that evoke this response. The aim of the study was to identify regions within HCMV pp65 (ppUL83) that contain sequences for t...

journal_title：Journal of medical virology

authors： Khattab BA,Lindenmaier W,Frank R,Link H

更新日期：1997-05-01 00:00:00

abstract：:The quantitation of serum levels of hepatitis C virus (HCV) RNA in chronic hepatitis C has been regarded as one of the most important indicators for the outcome of interferon (IFN) therapy. The AMPLICOR HCV MONITOR version 1.0 (AMPLICOR v1.0) assay is widely used for the evaluation of the HCV level. A new generation a...

journal_title：Journal of medical virology

authors： Kawai S,Yokosuka O,Imazeki F,Saisho H,Mizuno C

更新日期：2002-11-01 00:00:00

abstract：:In order to assess the current seroepidemiology of hepatitis D virus (HDV) infection in Taiwan where hepatitis B virus (HBV) is hyperendemic, a total of 756 voluntary blood donors, 641 prostitutes, 1,014 patients with sexually transmitted diseases (STDs), and 628 drug abusers were studied. Radioimmunoassays were used ...

journal_title：Journal of medical virology

authors： Chen CJ,Tseng SF,Lu CF,Lin HC,You SL,Chen CS,Hwang SJ,Hsieh SF,Hsu ST

更新日期：1992-10-01 00:00:00

abstract：:Antigenic drift of the hemagglutinin (HA) and neuraminidase (NA) proteins of the influenza virus cause a decrease in vaccine efficacy. Since the information about the evolution of these viruses in Saudi is deficient so we investigated the genetic diversity of circulating H1N1 viruses. Nasopharyngeal aspirates/swabs co...

journal_title：Journal of medical virology

authors： Naeem A,Elbakkouri K,Alfaiz A,Hamed ME,Alsaran H,AlOtaiby S,Enani M,Alosaimi B

更新日期：2020-03-11 00:00:00

abstract：:This study aimed to investigate the characteristics of female high-risk human papillomavirus (HR-HPV) infection in Shaanxi province of China. A total of 14 111 women were enrolled for HPV genotyping test, and a cytology, and/or cervix biopsy were performed in partial women. Of these women, the HPV infection rate was 3...

journal_title：Journal of medical virology

authors： Cao D,Zhang S,Zhang Q,Wei X,Zhao M,Ma Q,Li Y,Wang L,Pei M,Yang T,Zhao J,Yang X

更新日期：2017-07-01 00:00:00

abstract：:At present eight hepatitis B virus (HBV) genotypes have been characterized: A to H. The most common genotype in Northern Europe is genotype A. So far there is no record of the specific HBV genotype distribution in Iceland. Iceland has a small population whose homogeneity has changed due to increasing migration during ...

journal_title：Journal of medical virology

authors： Björnsdottir TB,Stanzeit B,Sällberg M,Löve A,Hultgren C

更新日期：2005-12-01 00:00:00

abstract：:It was reported previously that HCV can be transmitted from persistently infected human bone-marrow-derived B-lymphoblastoid cells (TO.FE(HCV)) to human hepatoma cells by cell-to-cell contact. The present study confirms and characterize further such type of HCV infection in vitro. TO.FE(HCV) cells were co-cultured wit...

journal_title：Journal of medical virology

authors： Valli MB,Crema A,Lanzilli G,Serafino A,Bertolini L,Ravagnan G,Ponzetto A,Menzo S,Clementi M,Carloni G

更新日期：2007-10-01 00:00:00