Abstract:
:Studies have shown that swine HEV (sHEV) and rabbit HEV (rHEV) can experimentally infect rabbits and swine, respectively. However, no published data have documented isolating sHEV strains from rabbits in natural environment so far. To clarify the possibility of natural cross-species transmission of sHEV to rabbits, the pigs with HEV infection were farmed along with SPF rabbits in the same enclosed space. Five of 10 rabbits had seroconversion for anti-HEV antibody from the third week after mix-breeding. However, HEV RNA remained undetectable in feces, serum, liver and bile of the ten rabbits; and no obvious elevation of ALT was observed. The results possibly suggested that sHEV might lead to an inapparent infection of SPF rabbits by fecal-oral route.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Liu L,Wang L,Xia J,Zhang Y,Zeng H,Liu P,Zou Q,Wang L,Zhuang Hdoi
10.1002/jmv.24374subject
Has Abstractpub_date
2016-04-01 00:00:00pages
681-5issue
4eissn
0146-6615issn
1096-9071journal_volume
88pub_type
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