Activation of cellular oncogenes by clinical isolates and laboratory strains of human cytomegalovirus.

abstract：:Persistent Epstein-Barr virus (EBV) infection is controlled tightly by virus-specific T cells. EBV infection is reactivated intermittently over time, even in apparently healthy carriers. Changes in frequency and reactivity of memory T cells, particularly of CD8(+) origin, have not been assessed in this context. It is ...

journal_title：Journal of medical virology

authors： Vogl BA,Fagin U,Nerbas L,Schlenke P,Lamprecht P,Jabs WJ

更新日期：2012-01-01 00:00:00

abstract：:The relative frequency and distribution of the VP4 (P) genotypes of 227 human rotavirus field strains were investigated in South Africa. The stool samples were collected between 1984-1993 from infants and young children with diarrhea at Ga-Rankuwa Hospital, Pretoria, South Africa. The RNA was extracted from stools, he...

journal_title：Journal of medical virology

authors： Mphahlele MJ,Steele AD

更新日期：1995-09-01 00:00:00

abstract：:Seventeen out of 30 patients with chronic hepatitis type B with hepatitis B e antigen (HBeAg) in serum remained persistently positive for e antigen, while 13 seroconverted to antibody (anti-HBe) when followed over a period of one to five years. Initial levels of serum hepatitis B virus (HBV) markers, such as the hepat...

journal_title：Journal of medical virology

authors： Alberti A,Pontisso P,Realdi G

更新日期：1982-01-01 00:00:00

abstract：:The relationship between cytomegalovirus (CMV) infection and cardiac allograft rejection is controversial, some authors reporting a significant association, others not, on the basis of the results of conventional virological diagnosis by culture or serology. This problem was reinvestigated in 88 patients using a semi-...

journal_title：Journal of medical virology

authors： Fernando S,Booth J,Boriskin Y,Butcher P,Carrington D,Steel H,Tryhorn Y,Corbishley C,Keeling P,Murday A

更新日期：1994-04-01 00:00:00

abstract：:Multiple determinants are involved in the progression of human papillomavirus (HPV)-infected cervical lesion to invasive cancer. Human leukocyte antigen (HLA) polymorphism seems to play a role. This study examined the association between HLA-DRB1 polymorphism, high-risk HPV infection, and the development of cervical n...

journal_title：Journal of medical virology

authors： Chan PK,Cheung TH,Lin CK,Siu SS,Yim SF,Lo KW,Cheung JL,Tam AO,Tang JW

更新日期：2007-07-01 00:00:00

abstract：:A reverse transcription-polymerase chain reaction (RT-PCR) was developed for the detection of Chikungunya virus infection. Based on the nonstructural protein 1 (nsP1) and glycoprotein E1 (E1) genes of Chikungunya, two primer sets were designed. Total RNA were extracted from the cell culture fluid of Aedes albopictus C...

journal_title：Journal of medical virology

authors： Hasebe F,Parquet MC,Pandey BD,Mathenge EG,Morita K,Balasubramaniam V,Saat Z,Yusop A,Sinniah M,Natkunam S,Igarashi A

更新日期：2002-07-01 00:00:00

abstract：:Saliva and peripheral blood samples from 20 healthy adults were examined for the presence of human herpesvirus-6 (HHV-6) DNA sequences using the polymerase chain reaction. Eighteen out of 20 whole saliva samples contained detectable HHV-6 genomes. The majority of peripheral blood samples were also positive; however, t...

journal_title：Journal of medical virology

authors： Jarrett RF,Clark DA,Josephs SF,Onions DE

更新日期：1990-09-01 00:00:00

abstract：:During 2002, an upsurge in frequency of hepatitis A outbreaks among injecting drug users was observed in England and Wales. As lack of risk factor information and the high mobility of the cases made linkage of outbreaks difficult, the relationship of nucleotide sequences in the VP1/2PA junction of the hepatitis A viru...

journal_title：Journal of medical virology

authors： Ngui SL,Granerod J,Jewes LA,Crowcroft NS,Teo CG,2002 Hepatitis A Outbreaks Investigation Network.

更新日期：2008-07-01 00:00:00

abstract：:The effect of protamine, atropine, selenocystamine, taxifolin, and catechin on the infectivity and antigenicity of the cell culture-adapted hepatitis A virus (HAV) strain CF 53 was studied. The toxicity on uninfected PLC/PRF/5 cells was examined for each antiviral compound by morphological and biochemical methods, in ...

journal_title：Journal of medical virology

authors： Biziagos E,Crance JM,Passagot J,Deloince R

更新日期：1987-05-01 00:00:00

abstract：:Hepatitis E virus (HEV) is a feco-orally transmitted pathogen and one of the most common cause of acute hepatitis worldwide. Recent studies in developed countries suggested that a direct human-to-human contact such as for sexually transmitted diseases may play a significant role in the HEV spread. The aim of this stud...

journal_title：Journal of medical virology

authors： Greco L,Uceda Renteria SC,Guarneri D,Orlandi A,Zoccoli A,Benardon S,Cusini M,Lunghi G

更新日期：2018-08-01 00:00:00

abstract：:As a consequence of the high prevalence of TorqueTeno virus (TTV) in blood donors, thalassemia patients frequently acquire various genotypes of this virus through therapeutic blood transfusions. At present, the clinical consequences of TTV infection remain indeterminate for these patients. Here, several hundred thalas...

journal_title：Journal of medical virology

authors： Hu YW,Al-Moslih MI,Al Ali MT,Uzicanin S,Perkins H,Yi QL,Rahimi Khameneh S,Wu J,Brown EG

更新日期：2008-02-01 00:00:00

abstract：:This study analyzed the genotype distribution and frequency of lamivudine (LAM) and tenofovir (TDF) resistance mutations in a group of patients co-infected with HIV and hepatitis B virus (HBV). A cross-sectional study of 847 patients with HIV was conducted. Patients provided blood samples for HBsAg detection. The load...

journal_title：Journal of medical virology

authors： Mendes-Correa MC,Pinho JR,Locarnini S,Yuen L,Sitnik R,Santana RA,Gomes-Gouvêa MS,Leite OM,Martins LG,Silva MH,Gianini RJ,Uip DE

更新日期：2010-09-01 00:00:00

abstract：:Hepatitis A virus (HAV) is usually transmitted by an oral-fecal route and is prevalent not only in developing countries but also in developed countries. In the present study, the phylogenetic characterization of the VP1/2A junction region (321 nucleotides) of China HAV isolates was examined. Anti-HAV IgM-positive seru...

journal_title：Journal of medical virology

authors： Cao J,Bi S,Meng Q,Shen L,Zheng H,Zhang Y

更新日期：2011-07-01 00:00:00

abstract：:Hepatitis C virus (HCV), exhibits considerable genetic diversity, but presents a relatively well conserved 5' noncoding region (5' NCR) among all genotypes. In this study, the structural features and translational efficiency of the HCV 5' NCR sequences were analyzed using the programs RNAfold, RNAshapes and RNApdist a...

journal_title：Journal of medical virology

authors： Araújo FM,Machado-Lima A,Durham AM,Teixeira R,Oliveira G

更新日期：2009-07-01 00:00:00

abstract：:The impact of cytomegalovirus (CMV) infection of the genital tract during pregnancy on adverse pregnancy outcomes is not understood fully. A real-time PCR assay was used to determine vaginal shedding of CMV in 993 healthy pregnant Japanese women and the results were compared with the outcome of pregnancy. CMV DNA was ...

journal_title：Journal of medical virology

authors： Tanaka K,Yamada H,Minami M,Kataoka S,Numazaki K,Minakami H,Tsutsumi H

更新日期：2006-06-01 00:00:00

abstract：:To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok...

journal_title：Journal of medical virology

authors： Li X,Zai J,Wang X,Li Y

更新日期：2020-04-01 00:00:00

abstract：:In vitro incubation of human cytomegalovirus (Towne strain) with 8 U/ml human recombinant myeloperoxidase plus sodium chloride and glucose nearly abolished viral infectivity. To assay the effect on intracellular infection, cell toxicity of the enzymes was first studied. Even the high dose of 16 U/ml of recombinant mye...

journal_title：Journal of medical virology

authors： El Messaoudi K,Verheyden AM,Thiry L,Fourez S,Tasiaux N,Bollen A,Moguilevsky N

更新日期：2002-02-01 00:00:00

abstract：:We investigated the molecular epidemiology and biological characteristics of wild measles viruses isolated since 1984 in Japan. The circulating measles virus was of genotype C1 before 1985, D3 from 1987 to 1990, and D5 from 1990 to 1997. It was replaced by the same cluster of Chicago-type D3 strain from 1997 to 1999. ...

journal_title：Journal of medical virology

authors： Zhou J,Fujino M,Inou Y,Kumada A,Aoki Y,Iwata S,Nakayama T

更新日期：2003-08-01 00:00:00

abstract：:Serial determinations of titers of binding antibodies to single stranded DNA were performed over a period of three years in 43 type B hepatitis patients with persisting HBsAg who had either developed chronic hepatitis or were asymptomatic carriers. Patients with histopathological diagnosis of chronic active or chronic...

journal_title：Journal of medical virology

authors： Villarejos VM,Serra J,Visoná KA,Eduarte CE

更新日期：1979-01-01 00:00:00

abstract：:Human metapneumovirus (hMPV) has been described as circulating among the Uruguayan population at least since 1998 based on serologic evidence. However, no isolation attempts, molecular detection, or genetic studies have been carried out so far in the country. In the present study, molecular detection of circulating hM...

journal_title：Journal of medical virology

authors： Pizzorno A,Masner M,Médici C,Sarachaga MJ,Rubio I,Mirazo S,Frabasile S,Arbiza J

更新日期：2010-05-01 00:00:00

abstract：:Herpes simplex virus (HSV)-specific IgG and IgA antibody response in patients with HSV infection and in healthy adults was studied by the immunoperoxidase antibody-membrane antigen (IPAMA) technique. In all HSV infections in which specific IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA), a si...

journal_title：Journal of medical virology

authors： Hadar T,Sarov I

更新日期：1984-01-01 00:00:00

abstract：:Although occult hepatitis B virus (HBV) infection in individuals without detectable hepatitis B surface antigen (HBsAg) may occur and has been reported to be common in patients with chronic hepatitis C, the related molecular mechanisms remain unknown. With the polymerase chain reaction, serum HBV DNA was sought in 100...

journal_title：Journal of medical virology

authors： Kao JH,Chen PJ,Lai MY,Chen DS

更新日期：2002-10-01 00:00:00

abstract：:Human bocavirus (HBoV) was first recognized in respiratory samples in 2005. The clinical importance of HBoV infection remains unclear. This report describes the clinical features and molecular phylogeny of HBoV isolates in children with acute respiratory infections. Nasopharyngeal aspirates were obtained from 1,528 ch...

journal_title：Journal of medical virology

authors： Ahn JG,Choi SY,Kim DS,Kim KH

更新日期：2014-12-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) is an important opportunistic pathogen in immunocompromised individuals and is recognized as a major viral cause of birth defects. HCMV has the ability to establish lifelong persistence and latent infection following primary exposure. Apoptosis is an innate cellular defense response to vir...

journal_title：Journal of medical virology

authors： Li HP,Yuan CL,Zho YC

更新日期：2015-11-01 00:00:00

abstract：:To investigate whether vertical transmission of the human herpesvirus 8 (HHV-8) may occur during pregnancy or at delivery, we enrolled 295 women recruited attending the Division of Obstetrics and Gynecology of a University Teaching of Rome Tor Vergata, S. Eugenio Hospital. The study population was divided in two group...

journal_title：Journal of medical virology

authors： Sarmati L,Carlo T,Rossella S,Montano M,Adalgisa P,Rezza G,Andreoni M

更新日期：2004-03-01 00:00:00

abstract：:We studied epidemiologic and immunologic factors in infants with bronchiolitis caused by influenza virus. The proportion of these infants who were male and who had an immediate family member with a history of asthma was similar to that of a control group of infants with respiratory syncytial virus (RSV) bronchiolitis....

journal_title：Journal of medical virology

authors： Garofalo RP,Hintz KH,Hill V,Patti J,Ogra PL,Welliver RC Sr

更新日期：2005-02-01 00:00:00

abstract：:Corticosteroid use in transplant recipients increases the incidence and severity of Kaposi's sarcoma (KS), a disease associated with KS-associated herpesvirus (KSHV) infection. Recently, the prototypic corticosteroid, hydrocortisone, was shown to directly induce lytic cycle reactivation of KSHV in latently-infected BC...

journal_title：Journal of medical virology

authors： Zoeteweij JP,Rinderknecht AS,Davis DA,Yarchoan R,Blauvelt A

更新日期：2002-03-01 00:00:00

abstract：:The risk and clearance of GB virus type C (GBV-C)/hepatitis G virus (HGV) infection was investigated in a cohort of homosexual men (n=180; median follow-up time, 7 years). The interaction between GBV-C/HGV RNA and antibodies against the E2 region of the virus, and the clinical impact of chronic GBV-C/HGV infection wer...

journal_title：Journal of medical virology

authors： Stark K,Doering CD,Bienzle U,Pauli G,Hamouda O,Engel AM,Schreier E

更新日期：1999-11-01 00:00:00

abstract：:Inosine triphosphatase (ITPA) gene variants can protect against ribavirin (RBV)-induced anemia in patients treated for chronic hepatitis C. The aim of this study was to determine the relationship between genetic variants of ITPA polymorphism, anemia, RBV dose reduction, and treatment response in hepatitis C virus (HCV...

journal_title：Journal of medical virology

authors： El Raziky M,Zayed NA,Abdel Baki A,Mansour SA,Shahin RMH

更新日期：2017-10-01 00:00:00

abstract：:In early 2008, a sudden increase in oseltamivir (Tamiflu)-resistant influenza A H1N1 viruses was reported from several European countries. This resistant virus has spread globally and accounted for more than 95% of H1N1 viruses isolated in the following influenza season. A continuous close monitoring on the prevalence...

journal_title：Journal of medical virology

authors： Ngai KL,Lam WY,Lee N,Leung TF,Hui DS,Chan PK

更新日期：2010-08-01 00:00:00