Association of cytomegalovirus infection with post-transplantation cardiac rejection as studied using the polymerase chain reaction.

abstract：:Hepatitis C Virus (HCV) NS3 protease is an attractive target for antiviral agent development because it is required for viral replication. Because a stable cell culture system or small animal model to study HCV replication is not readily available, we constructed an in vitro model allowing the investigation of NS3 tra...

journal_title：Journal of medical virology

authors： Heintges T,Encke J,zu Putlitz J,Wands JR

更新日期：2001-12-01 00:00:00

abstract：:Citrullinated histone H3 (H3Cit) is the product of the conversion of peptidylarginine to citrulline in histone H3. We evaluated the H3Cit level in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) tissues and assessed its association with Beclin1 messenger RNA (mRNA) (a key autophagic regulator). The leve...

journal_title：Journal of medical virology

authors： Lu M,Zhang X,Xu Y,He G,Liu Q,Zhu J,Zhang C

更新日期：2020-08-01 00:00:00

abstract：:A novel simultaneous detection system for human viruses was developed using a real-time polymerase chain reaction (PCR) system to identify causes of infection in clinical samples from patients with uncertain diagnoses. This system, designated as the "multivirus real-time PCR," has the potential to detect 163 human vir...

journal_title：Journal of medical virology

authors： Katano H,Kano M,Nakamura T,Kanno T,Asanuma H,Sata T

更新日期：2011-02-01 00:00:00

abstract：:A sensitive and reproducible real-time PCR assay based on TaqMan technology was developed for the detection and quantitation of hepatitis B virus (HBV) DNA in serum, and compared with an "in-house" qualitative PCR assay. HBV DNA was measured in 125 serum samples from 76 hepatitis B patients, consisting of 22 patients ...

journal_title：Journal of medical virology

authors： Chen RW,Piiparinen H,Seppänen M,Koskela P,Sarna S,Lappalainen M

更新日期：2001-10-01 00:00:00

abstract：:Thirty-nine children without previous cytomegalovirus (CMV) infection received blood transfusion in the National Taiwan University Hospital. The overall transfusion-acquired CMV infection rate was 36% (14/39). Donor CMV seropositive rate was 70%. None of the nine children who had received seronegative blood became inf...

journal_title：Journal of medical virology

authors： Lee PI,Chang MH,Hwu WL,Kao CL,Lee CY

更新日期：1992-01-01 00:00:00

abstract：:DNA plasmids are potent inducers of long-lasting antigen-specific CTL responses. Little is known about the distribution of antigen-specific CD8+ T cells in the lymphoid tissue and the non-lymphoid tissue after DNA immunization. HBsAg-specific CD8+ T cells in peripheral blood mononuclear cells, spleen, lymph nodes, and...

journal_title：Journal of medical virology

authors： Qu D,Lanier G,Yuan ZH,Wen YM,Howard CR,Ahmed R

更新日期：2008-02-01 00:00:00

abstract：:Most cases of hepatocellular carcinoma (HCC) are due to chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection worldwide. The aim of this study was to determine the viral genotypes and frequency of 17 mutations (15 for HBV and 2 for HCV), described previously as able to influence the course of chronic li...

journal_title：Journal of medical virology

authors： Araujo OC,Barros JJ,do Ó KM,Nabuco LC,Luz CA,Perez RM,Niel C,Villela-Nogueira CA,Araujo NM

更新日期：2014-02-01 00:00:00

abstract：:Chronic papillary conjunctivitis has been described following adenoviral conjunctivitis. It is unknown however, how long adenovirus is able to persist in the tear film and conjunctiva. To determine if adenovirus persists in the ocular surface following adenoviral conjunctivitis, 304 patients with a history of adenovir...

journal_title：Journal of medical virology

authors： Kaye SB,Lloyd M,Williams H,Yuen C,Scott JA,O'Donnell N,Batterbury M,Hiscott P,Hart CA

更新日期：2005-10-01 00:00:00

abstract：:Human papillomaviruses (HPV) are the causative agents of most cervical carcinomas. A complete understanding of the HPV types that cause cervical carcinoma is needed as vaccines are designed. Fresh tissues are not always available for such studies. We therefore sought to determine the feasibility of HPV studies using f...

journal_title：Journal of medical virology

authors： Bryan JT,Taddeo F,Skulsky D,Jansen KU,Frain BM,Qadadri B,Brown DR

更新日期：2006-01-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) play a central role in tumor invasion and metastasis. Increased expression of MMPs occurs during development of hepatocellular carcinoma (HCC) in humans following infection with hepatitis B virus (HBV). Woodchucks are used as an animal model for hepadnavirus-induced HCC. All woodchucks...

journal_title：Journal of medical virology

authors： Ochoa-Callejero L,Toshkov I,Menne S,Martínez A

更新日期：2013-07-01 00:00:00

abstract：:Epstein-Barr virus (EBV) reactivation and cell-mediated immune (CMI) responses were followed in 16 Antarctic expeditioners during winter-over isolation at 2 Australian National Antarctic Research Expedition stations. Delayed-type hypersensitivity (DTH) skin testing was used as an indicator of the CMI response, that wa...

journal_title：Journal of medical virology

authors： Mehta SK,Pierson DL,Cooley H,Dubow R,Lugg D

更新日期：2000-06-01 00:00:00

abstract：:A multiplex polymerase chain reaction (PCR) assay that is capable of detecting and typing six serotypes of respiratory adenovirus (Ad) was developed, using multiple sets of type-specific primers. The detection of each different serotype depended on distinguishing different numbers and sizes of amplification products o...

journal_title：Journal of medical virology

authors： Na BK,Kim JH,Shin GC,Lee JY,Lee JS,Kang C,Kim WJ

更新日期：2002-04-01 00:00:00

abstract：:No controlled trial in patients with chronic hepatitis B virus (HBV) infection on long-term entecavir (ETV) treatment, comparing switching to tenofovir disoproxil fumarate (TDF) with continuing the therapy, has been reported. Twenty-seven nucleos(t)ide-naïve patients with chronic HBV who underwent ETV therapy for ≥5 y...

journal_title：Journal of medical virology

authors： Iida-Ueno A,Enomoto M,Kozuka R,Tamori A,Kawada N

更新日期：2019-07-01 00:00:00

abstract：:Human T-cell lymphotropic virus (HTLV) antibody screening is not recommended uniformly before transplantation in Western countries. In the year 2001, the first cases of HTLV-I infection acquired through organ transplantation from one asymptomatic carrier were reported in Europe. All three organ recipients developed a ...

journal_title：Journal of medical virology

authors： Toro C,Benito R,Aguilera A,Bassani S,Rodríguez C,Calderón E,Caballero E,Alvarez P,García J,Rodríguez-Iglesias M,Guelar A,del Romero J,Soriano V,HTLV Spanish Study Group.

更新日期：2005-06-01 00:00:00

abstract：:Hepatitis B virus (HBV) e antigen (HBeAg) seroconversion during chronic HBV infection is known to play an important role in disease progression and patient response to antiviral agents. The aim of the present study was to analyze gender disparity in distribution of major hydrophilic region (MHR) variants according to ...

journal_title：Journal of medical virology

authors： Lee SA,Cho YK,Lee KH,Hwang ES,Kook YH,Kim BJ

更新日期：2011-03-01 00:00:00

abstract：:HCV replication in extra-hepatic reservoirs has been suggested to occur in many tissues including PBMCs. A recent study showed evidence for compartmentalization and evolution of HCV in PBMCs. However, the cells that support HCV replication in PBMCs have not been identified. In this study we have fractionated the PBMC ...

journal_title：Journal of medical virology

authors： Natarajan V,Kottilil S,Hazen A,Adelsberger J,Murphy AA,Polis MA,Kovacs JA

更新日期：2010-12-01 00:00:00

abstract：:Serial serum samples from 20 untreated patients with chronic hepatitis C virus (HCV) infection were tested for HCV RNA by a nested polymerase chain reaction assay using primers from the highly conserved 5' noncoding region to determine the relationship between hepatitis C viremia and the activity of liver disease duri...

journal_title：Journal of medical virology

authors： Cheung RC,Chan RT,Lok AS

更新日期：1993-12-01 00:00:00

abstract：:The ability of the anti-cancer drug, 9-Nitrocamptothecin (9NC), to inhibit replication of HIV-1 in clinically relevant primary lymphocytic cells was studied. Primary peripheral blood lymphocytes (PBLs) from a non-infected donor were freshly infected with HIV-1 and treated with 9NC by using three different treatment sc...

journal_title：Journal of medical virology

authors： Hung CL,Doniger J,Palini A,Snyder SW,Radonovich MF,Brady JN,Pantazis P,Sadaie MR

更新日期：2001-07-01 00:00:00

abstract：:The quantification of human immunodeficiency virus type 1 (HIV-1) RNA or hepatitis C virus (HCV) RNA has been facilitated by adapting a spin column procedure for sample preparation and the use of chemiluminescent detection of polymerase chain reaction (PCR) products in microtiter plate format. All materials were comme...

journal_title：Journal of medical virology

authors： Lin HJ,Tanwandee T,Hollinger FB

更新日期：1997-01-01 00:00:00

abstract：:Human T-cell lymphotropic virus 1 (HTLV-1) is associated with two progressive diseases: HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukemia/lymphoma (ATLL). Although HTLV-1 proviral load (PVL) has been introduced as a risk factor for these diseases' progression, it is not suff...

journal_title：Journal of medical virology

authors： Mozhgani SH,Jaberi N,Rezaee SA,Bustani R,Jazayeri SM,Akbarin MM,Milani S,Tarokhian H,Norouzi M

更新日期：2017-06-01 00:00:00

abstract：:A rapid technique for the detection of hepatitis C virus (HCV) RNA in liver section using nonisotopic in situ hybridization was described. Only 3 of the 10 patients seropositive for antibody to HCV and HCV RNA had detectable HCV RNA in the hepatocytes (1%, 2%, and 15% of cells positive). No specific signal was detecte...

journal_title：Journal of medical virology

authors： Lau JY,Davis GL

更新日期：1994-03-01 00:00:00

abstract：:Lack of recognition of human immunodeficiency virus (HIV) infection especially in children and delayed implementation of effective control programs makes HIV infection as a major cause for concern. Information on HIV epidemiology in Iran as well as other Islamic countries is limited. The aim of our study was to descri...

journal_title：Journal of medical virology

authors： Movahedi Z,Mahmoudi S,Pourakbari B,Keshavarz Valian N,Sabouni F,Ramezani A,Bahador A,Mamishi S

更新日期：2016-01-01 00:00:00

abstract：:Female renal transplant recipients have an increased incidence of human papillomavirus (HPV) associated lesions, such as cervical dysplasia and neoplasia [Schneider et al., 1983]. In this study we tested the serological responses by enzyme-linked immunoadsorbent assays (ELISA) to 3 different antigenic regions of HPV t...

journal_title：Journal of medical virology

authors： Lewensohn-Fuchs I,Wester D,Bistoletti P,Elfgren K,Ohlman S,Dillner J,Dalianis T

更新日期：1993-07-01 00:00:00

abstract：:The genotypes and subtypes of 205 HBV isolates collected during 1989-2002 in Estonia and 14 other regions of the former USSR were determined by sequencing and phylogenetic analysis of the S gene. The in Europe prevailing genotypes, A and D, were also circulating in the whole territory of the former USSR including Esto...

journal_title：Journal of medical virology

authors： Tallo T,Norder H,Tefanova V,Krispin T,Priimägi L,Mukomolov S,Mikhailov M,Magnius LO

更新日期：2004-10-01 00:00:00

abstract：:To determine risk factors responsible for primary cytomegalovirus (CMV) infection in Taiwan, samples of blood for antibody to CMV were obtained from 362 children aged 4 to 12 years: 58% were found to be positive for anti-CMV IgG antibody. Logistic regression analysis showed that seropositivity correlated with age, met...

journal_title：Journal of medical virology

authors： Shen CY,Chang WW,Chang SF,Chao MF,Huang ES,Wu CW

更新日期：1992-05-01 00:00:00

abstract：:A common receptor for coxsackie B virus and adenovirus has been described recently in cells of human and murine origin. Since the established cell line A-549 is suitable for adenoviruses, the potential use of A-549 cells for the isolation of coxsackie B viruses from clinical samples was investigated. All throat swabs ...

journal_title：Journal of medical virology

authors： Otero JR,Folgueira L,Trallero G,Prieto C,Maldonado S,Babiano MJ,Martinez-Alonso I

更新日期：2001-11-01 00:00:00

abstract：:Lymphocytic choriomeningitis virus (LCMV), which is one of several arenaviruses that are pathogenic for humans, causes encephalitis and meningitis in man. In this study, single-stage and nested reverse transcription-polymerase chain reaction (RT-PCR) assays were developed that targeted the GPC and N genes of LCMV. Bot...

journal_title：Journal of medical virology

authors： Park JY,Peters CJ,Rollin PE,Ksiazek TG,Gray B,Waites KB,Stephensen CB

更新日期：1997-02-01 00:00:00

abstract：:A solution of pooled cryo-precipitate for preparing factor VIII (F VIII) by the solvent/detergent method was contaminated experimentally with parvovirus B19-positive plasma to evaluate virus reduction achieved by the final steps of the F VIII production process. Virus reduction was at least 2 logs of the total amount ...

journal_title：Journal of medical virology

authors： Schwarz TF,Roggendorf M,Hottenträger B,Stolz W,Schwinn H

更新日期：1991-09-01 00:00:00

abstract：:Hemorrhagic fever with renal syndrome (HFRS) is a severe acute viral disease with pathological changes of impaired capillary and small vessels and thrombocytopenia. In this study, serum thrombospondin (TSP)-1 concentration in patients with HFRS was determined to explore its possible role in the pathogenesis of HFRS. T...

journal_title：Journal of medical virology

authors： Liu Z,Zhao Q,Han Q,Gao M,Zhang N

更新日期：2008-10-01 00:00:00

abstract：:The live varicella vaccine has been recommended for use in immunocompromised subjects and in adults who are susceptible to chickenpox. However, we do not know how humoral and cell-mediated immune responses induced after vaccination differed from those obtained after natural infection. To answer this, 45 previously inf...

journal_title：Journal of medical virology

authors： Ndumbe PM,Cradock-Watson J,Levinsky RJ

更新日期：1988-06-01 00:00:00