Detection of human herpesvirus-6 DNA in peripheral blood and saliva.

Abstract:

:Saliva and peripheral blood samples from 20 healthy adults were examined for the presence of human herpesvirus-6 (HHV-6) DNA sequences using the polymerase chain reaction. Eighteen out of 20 whole saliva samples contained detectable HHV-6 genomes. The majority of peripheral blood samples were also positive; however, the results suggest that only a rare cell in the peripheral blood is infected. Serological studies did not reveal any correlation between HHV-6 antibody titre and the ability to detect HHV-6 DNA. The data indicate that HHV-6 genomes persist in the peripheral blood and oropharynx or salivary glands of most healthy individuals following primary infection.

journal_name

J Med Virol

authors

Jarrett RF,Clark DA,Josephs SF,Onions DE

doi

10.1002/jmv.1890320113

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

73-6

issue

1

eissn

0146-6615

issn

1096-9071

journal_volume

32

pub_type

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