Human T-cell lymphotropic virus antibody prevalence in HIV-1-infected individuals attending a sexual health clinic in South-East London.

Abstract:

:Human immunodeficiency virus (HIV) and human T-cell lymphotropic virus (HTLV) are both retroviruses with similar routes of transmission. A number of reports suggest variable clinical outcomes in HIV and HTLV co-infected individuals. There is no published information regarding the prevalence of HIV and HTLV co-infection in the UK. We therefore carried out an unlinked anonymised retrospective study to investigate the prevalence of HTLV co-infection in HIV infected patients attending a sexual health clinic in South-East London. We identified sera from 777 HIV-1 positive adults (504 male, 273 female) who had attended our sexual health clinic between January 2000 and March 2001. Serum samples stored at -20 degrees C were initially tested by HTLV-1 and HTLV-2 antibody enzyme-linked immunoassay (EIA). An immunoblot assay was carried out on reactive samples to discriminate between viral subtypes. Samples with indeterminate results were also analyzed by Western blot. The prevalence of HTLV antibody was 0.8% (five patients with HTLV-1 and one with HTLV-2). Four of the HTLV-1 co-infected patients were females born abroad, of Black African or Caribbean origin. The other HTLV-1-infected patient was a male in the Black Other ethnic group born in the UK, demonstrating that transmission may occur outside recognized areas of high endemicity. The HTLV-2 co-infected individual was a White male born in Italy, and was likely to have been infected through intravenous drug use. The results suggest HTLV antibody screening should be considered in the local HIV infected population of south London.

journal_name

J Med Virol

authors

Cooke FJ,Geretti AM,Zuckerman M

doi

10.1002/jmv.20336

keywords:

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

143-5

issue

2

eissn

0146-6615

issn

1096-9071

journal_volume

76

pub_type

杂志文章
  • Specific IgG and IgA antibodies to herpes simplex virus (HSV)-induced surface antigen in patients with HSV infections and in healthy adults.

    abstract::Herpes simplex virus (HSV)-specific IgG and IgA antibody response in patients with HSV infection and in healthy adults was studied by the immunoperoxidase antibody-membrane antigen (IPAMA) technique. In all HSV infections in which specific IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA), a si...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890140303

    authors: Hadar T,Sarov I

    更新日期:1984-01-01 00:00:00

  • Evidence for superantigen activity of the Bel 3 protein of the human foamy virus.

    abstract::The human foamy virus is a complex retrovirus that codes for several regulatory bel genes in addition to the conventional gag, pol, and env genes. The bel 3 gene is located in the 3' part of the viral genome comparable to that of the superantigen of the mouse mammary tumor virus. Superantigens bound to major histocomp...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890440112

    authors: Weissenberger J,Altmann A,Meuer S,Flügel RM

    更新日期:1994-09-01 00:00:00

  • Prediction of the efficacy of antiviral therapy for hepatitis C virus infection by an ultrasensitive RT-PCR assay.

    abstract::The efficacy of interferon therapy for hepatitis C virus (HCV) infection improved remarkably. However, virologic relapse occurs in a substantial proportion of patients with virologic response (defined as an HCV RNA level below 50 IU/ml at the end-of-treatment). A highly sensitive RT-nested PCR assay capable of detecti...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20908

    authors: Kinai E,Hanabusa H,Kato S

    更新日期:2007-08-01 00:00:00

  • Is there any relationship between Toll-like receptor 3 c.1377C/T and -7C/A polymorphisms and susceptibility to Crimean Congo hemorrhagic fever?

    abstract::Crimean-Congo hemorrhagic fever (CCHF) is an infectious disease that is caused by CCHF virus. A family of transmembrane receptors called as Toll-like receptors (TLRs) selectively acts in recognizing a wide range of microbial components and endogenous molecules released by damaged tissue and have been preserved through...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24519

    authors: Engin A,Arslan S,Özbilüm N,Bakir M

    更新日期:2016-10-01 00:00:00

  • HIV antibodies in whole saliva detected by ELISA and western blot assays.

    abstract::Paired serum and saliva samples were tested by enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) for the presence of human immunodeficiency virus (HIV) antibodies. The study group included 36 individuals known to be HIV seropositive and 14 healthy, seronegative controls. HIV antibodies were detected in a...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890300403

    authors: Holmström P,Syrjänen S,Laine P,Valle SL,Suni J

    更新日期:1990-04-01 00:00:00

  • A community prevalence study of antibodies to hepatitis A and E in inner-city London.

    abstract::The seroprevalence of antibodies to hepatitis E virus (HEV) and hepatitis A virus (HAV) was determined in a community-based sample in innercity London where socioeconomic conditions were expected to result in a high prevalence of antibodies to HAV, and in which the presence of immigrants from the developing world pose...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9071(199607)49:3<230::AID-JMV12

    authors: Bernal W,Smith HM,Williams R

    更新日期:1996-07-01 00:00:00

  • Enterovirus 71 isolated from China is serologically similar to the prototype E71 BrCr strain but differs in the 5'-noncoding region.

    abstract::Enterovirus 71 H (E71 H), an isolate from an adult patient with hand-food-mouth disease (HFMD) in China, was serologically similar to the prototype strain E71 BrCr, which was isolated from a patient with aseptic meningitis. The study further analyzed the similarity of E71 H to E71 BrCr at the 5'-noncoding region (NCR)...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890470209

    authors: Zheng ZM,He PJ,Caueffield D,Neumann M,Specter S,Baker CC,Bankowski MJ

    更新日期:1995-10-01 00:00:00

  • Immunoblot detection of antibodies to Toscana virus.

    abstract::Sera from patients with sandfly fever caused by Toscana virus (TOSV) infection were tested by immunoblot for specific antibody response to TOSV derived from infected Vero-E6 cells. The 28 kDa TOSV nucleoprotein (N) was identified as the major immunodominant protein recognized by immunoblot. In sera of patients with ac...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9071(199606)49:2<83::AID-JMV2>3

    authors: Schwarz TF,Gilch S,Pauli C,Jäger G

    更新日期:1996-06-01 00:00:00

  • Low-level plasma HIVs in patients on prolonged suppressive highly active antiretroviral therapy are produced mostly by cells other than CD4 T-cells.

    abstract::The cellular source(s) and the clinical significance of persistent low-level viremia, below 50 HIV RNA copies per ml of plasma, achieved in many patients with high adherence to highly active antiretroviral therapy (HAART) remain unclear. Also, it is not clear if residual plasma HIVs during HAART can become predominant...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21366

    authors: Sahu GK,Paar D,Frost SD,Smith MM,Weaver S,Cloyd MW

    更新日期:2009-01-01 00:00:00

  • Hepatitis E virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention.

    abstract::Hepatitis E virus (HEV), the sole member of the genus Hepevirus in the family of Hepeviridae, is the major cause of several outbreaks of waterborne hepatitis in tropical and subtropical countries and of sporadic cases of viral hepatitis in endemic and industrialized countries. Transmission of HEV occurs predominantly ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.21116

    authors: Mushahwar IK

    更新日期:2008-04-01 00:00:00

  • Molecular characterization of the env gene of two CCR5/CXCR4-independent human immunodeficiency 2 primary isolates.

    abstract::Human immunodeficiency virus 2 (HIV-2) infection is characterized by a slower disease progression and lower transmission rates. The molecular features that could be assigned as directly involved in this in vivo phenotype remain essentially unknown, and the importance of HIV-2 as a model to understand pathogenicity of ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21619

    authors: Santos-Costa Q,Parreira R,Moniz-Pereira J,Azevedo-Pereira JM

    更新日期:2009-11-01 00:00:00

  • Localization of CD8+ cells specific for hepatitis B virus surface protein in the liver of immunized mice.

    abstract::DNA plasmids are potent inducers of long-lasting antigen-specific CTL responses. Little is known about the distribution of antigen-specific CD8+ T cells in the lymphoid tissue and the non-lymphoid tissue after DNA immunization. HBsAg-specific CD8+ T cells in peripheral blood mononuclear cells, spleen, lymph nodes, and...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21039

    authors: Qu D,Lanier G,Yuan ZH,Wen YM,Howard CR,Ahmed R

    更新日期:2008-02-01 00:00:00

  • Intratonsillar detection of 27 distinct viruses: A cross-sectional study.

    abstract::Palatine tonsils have been observed to harbor several distinct respiratory and herpesviruses in separate studies. In this study, the presence of these viruses in palatine tonsils was comprehensively studied in both children and adults. A cross-sectional analysis of 181 patients (median age 22 years; range, 2.6-66) ope...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26245

    authors: Silvoniemi A,Mikola E,Ivaska L,Jeskanen M,Löyttyniemi E,Puhakka T,Vuorinen T,Jartti T

    更新日期:2020-06-30 00:00:00

  • Prevalence and genotype distribution of cervical human papillomavirus infection in Macao.

    abstract::Population-specific epidemiological data on human papillomavirus (HPV) infection are essential for formulating strategies to prevent cervical cancer. The age-specific prevalence of HPV infection was determined among 1,600 women enrolled for cervical screening in Macao. A U-shaped age-specific prevalence curve with a f...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21826

    authors: Yip YC,Ngai KL,Vong HT,Tzang LC,Ji S,Yang M,Chan PK

    更新日期:2010-10-01 00:00:00

  • Deletions and single-base mutations within the carboxy-terminal region of the latent membrane protein 1 oncogene in Epstein-Barr virus-related gastric cancers of southern Japan.

    abstract::The 30-base pair (bp) deletion of the cytoplasmic carboxy-terminal domain of the latent membrane protein 1 (LMP-1) gene was analyzed in 37 frozen tissues from patients with Epstein-Barr virus (EBV)-related gastric cancer and 18 throat washings from healthy adults in southern Japan. The 30-bp deletion was identified in...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199902)57:2<152::aid-jmv11

    authors: Mori S,Itoh T,Tokunaga M,Eizuru Y

    更新日期:1999-02-01 00:00:00

  • Seroprevalence of six different viruses among pregnant women and blood donors in rural and urban Burkina Faso: A comparative analysis.

    abstract::A seroprevalence study was carried out of six different human pathogenic viruses, namely human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), human T-cell leukemia virus (HTLV), human herpesvirus type 8 (HHV-8), and dengue virus among pregnant women and blood donors from rural (Nouna) ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20593

    authors: Collenberg E,Ouedraogo T,Ganamé J,Fickenscher H,Kynast-Wolf G,Becher H,Kouyaté B,Kräusslich HG,Sangaré L,Tebit DM

    更新日期:2006-05-01 00:00:00

  • Complete coding regions of the prototypes enterovirus B93 and C95: phylogenetic analyses of the P1 and P3 regions of EV-B and EV-C strains.

    abstract::Complete coding regions were sequenced for two new enterovirus genomes: EV-B93 previously identified by VP1 sequencing, derived from a child with acute flaccid paralysis in the Democratic Republic of Congo; and EV-C95 from a French soldier with acute gastroenteritis in Djibouti. The EV-B93 P1 had more than 30% nucleot...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24062

    authors: Junttila N,Lévêque N,Magnius LO,Kabue JP,Muyembe-Tamfum JJ,Maslin J,Lina B,Norder H

    更新日期:2015-03-01 00:00:00

  • Serological evaluation of possible exposure to Ljungan virus and related parechovirus in autoimmune (type 1) diabetes in children.

    abstract::Exposure to Ljungan virus (LV) is implicated in the risk of autoimmune (type 1) diabetes but possible contribution by other parechoviruses is not ruled out. The aim was to compare children diagnosed with type 1 diabetes in 2005-2011 (n = 69) with healthy controls (n = 294), all from the Jämtland County in Sweden, usin...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24127

    authors: Nilsson AL,Vaziri-Sani F,Broberg P,Elfaitouri A,Pipkorn R,Blomberg J,Ivarsson SA,Elding Larsson H,Lernmark Å

    更新日期:2015-07-01 00:00:00

  • Naturally occurring hepatitis B surface gene variants in chronic hepatitis B virus infection: correlation with viral serotypes and clinical stages of liver disease.

    abstract::Virus variants escaping from host immunity may be implicated in the pathogenesis of hepatitis B virus (HBV) infection. In this cross-sectional study, the association was evaluated of the frequency of amino acid variation within the immunogenic epitopes of surface gene with different disease stages of chronic HBV infec...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10169

    authors: Liu CJ,Kao JH,Shau WY,Chen PJ,Lai MY,Chen DS

    更新日期:2002-09-01 00:00:00

  • UV-inactivated measles virus stimulates human and mice naive lymphocytes to proliferate in vitro.

    abstract::Ultra violet (UV) light-inactivated measles virus was used for the lymphocyte proliferation assay, where it caused consistently adult human peripheral blood monolymphocytes (PBML) proliferation which was not dependent on the measles virus complement fixation titre in the donor's sera. When the cord blood lymphocytes f...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890460209

    authors: Tu R

    更新日期:1995-06-01 00:00:00

  • Risk factors and clinical characteristics of patients with nosocomial influenza A infection.

    abstract::Influenza is a public health burden, responsible for more than half a million deaths worldwide each year and explosive outbreaks in-hospital care units. At present, little is known about clinical characteristics and outcomes with nosocomial influenza infection. To assess clinical characteristics and outcome between no...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25652

    authors: Naudion P,Lepiller Q,Bouiller K

    更新日期:2020-08-01 00:00:00

  • The impact of viral dynamics on the clinical severity of infants with respiratory syncytial virus bronchiolitis.

    abstract::The impact of dynamic respiratory syncytial virus (RSV) load on the clinical severity of hospitalized infants with bronchiolitis has not been clarified. Nasopharyngeal aspirates were obtained from 60 infants who were diagnosed with bronchiolitis within 96 hr of wheezing onset upon admission and on days 3, 5, and 7 in ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24111

    authors: Zhou L,Xiao Q,Zhao Y,Huang A,Ren L,Liu E

    更新日期:2015-08-01 00:00:00

  • Molecular and cellular determinants of cell-to-cell transmission of HCV in vitro.

    abstract::It was reported previously that HCV can be transmitted from persistently infected human bone-marrow-derived B-lymphoblastoid cells (TO.FE(HCV)) to human hepatoma cells by cell-to-cell contact. The present study confirms and characterize further such type of HCV infection in vitro. TO.FE(HCV) cells were co-cultured wit...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20947

    authors: Valli MB,Crema A,Lanzilli G,Serafino A,Bertolini L,Ravagnan G,Ponzetto A,Menzo S,Clementi M,Carloni G

    更新日期:2007-10-01 00:00:00

  • Dominant replication of either virus in dual infection with hepatitis viruses B and C.

    abstract::To characterize the state of dual infection with hepatitis B virus (HBV) and hepatitis C virus (HCV), HBV-DNA and HCV-RNA levels were determined by spot hybridization or polymerase chain reaction in the sera of patients who were positive for both hepatitis B surface antigen and HCV antibody. Among 27 patients who show...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890450222

    authors: Koike K,Yasuda K,Yotsuyanagi H,Moriya K,Hino K,Kurokawa K,Iino S

    更新日期:1995-02-01 00:00:00

  • Herd immunity and fatal cases of influenza among the population exposed to poultry and wild birds in Russian Asia in 2013-2014.

    abstract::In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24301

    authors: Ilyicheva T,Abdurashitov M,Durymanov A,Susloparov I,Goncharova N,Kolosova N,Mikheev V,Ryzhikov A

    更新日期:2016-01-01 00:00:00

  • Investigation of varicella-zoster virus DNA by the polymerase chain reaction in healthy children with varicella vaccination.

    abstract::Investigation of varicella-zoster virus (VZV) DNA in 20 healthy children with varicella vaccination was carried out by using the polymerase chain reaction (PCR) and nested double PCR. Samples of peripheral blood mononuclear cells (PBMC) and throat swabs were simultaneously collected 3 times (before, 1 week, and 4 week...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890420110

    authors: Ozaki T,Masuda S,Asano Y,Kondo K,Namazue J,Yamanishi K

    更新日期:1994-01-01 00:00:00

  • Sexual transmission of human T-lymphotropic virus type I in Peruvian prostitutes.

    abstract::The epidemiology of HTLV-I infection in female prostitutes was studied in a survey of 395 prostitutes from Callao, Peru (the port city of Lima), 72 prostitutes from Iquitos, Peru (another port city on the Amazon River), and 510 prenatal clinic patients from Lima. Prostitutes reported a mean of 8.8 years (range, 1-39 y...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890380110

    authors: Wignall FS,Hyams KC,Phillips IA,Escamilla J,Tejada A,Li O,Lopez F,Chauca G,Sanchez S,Roberts CR

    更新日期:1992-09-01 00:00:00

  • Characterization of in vitro dengue virus resistance to carrageenan.

    abstract::The λ-carrageenan (λ-car) is a potent and selective inhibitor of dengue virus (DENV) infection targeted to virus adsorption and internalization, due to the structural similarities with the mammalian cell receptor heparan sulfate. To further characterize the antiviral activity of λ-car, the selection and the phenotypic...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24457

    authors: Talarico LB,Damonte EB

    更新日期:2016-07-01 00:00:00

  • Treatment with cytotoxic immunosuppression agents increases urinary excretion of JCV in patients with autoimmune disease.

    abstract::Human JC virus is ubiquitous in human populations and is reactivated frequently in immunosuppressed patients. Fifty-one patients with autoimmune disease receiving immunomodulating therapy were evaluated to study the possible relationship between immunosuppression and JCV viruria. Patients were divided into cytotoxic a...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/1096-9071(200012)62:4<505::aid-jmv16>3.0.c

    authors: Wang M,Tsai RT,Ou WC,Lin CK,Tsay GJ,Chang H,Chang D

    更新日期:2000-12-01 00:00:00

  • Weathering the pandemic: How the Caribbean Basin can use viral and environmental patterns to predict, prepare, and respond to COVID-19.

    abstract::The 2020 coronavirus pandemic is developing at different paces throughout the world. Some areas, like the Caribbean Basin, have yet to see the virus strike at full force. When it does, there is reasonable evidence to suggest the consequent COVID-19 outbreaks will overwhelm healthcare systems and economies. This is par...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.25864

    authors: de Ángel Solá DE,Wang L,Vázquez M,Méndez-Lázaro PA

    更新日期:2020-09-01 00:00:00