A community prevalence study of antibodies to hepatitis A and E in inner-city London.

Abstract:

:The seroprevalence of antibodies to hepatitis E virus (HEV) and hepatitis A virus (HAV) was determined in a community-based sample in innercity London where socioeconomic conditions were expected to result in a high prevalence of antibodies to HAV, and in which the presence of immigrants from the developing world pose a risk of imported infection of both HAV and HEV. The seroprevalence of anti-HAV was 45.1% in UK born subjects and 69.7% in non-UK born subjects and each group showed differing patterns of age-specific seroprevalence. The seroprevalence rates of anti-HEV was 3.9% in UK born subjects and 8.8% in non-UK born subjects. The age-specific seroprevalence of the UK born group is suggestive of a cohort effect. The data suggest a low circulation of HEV in inner-city London, remaining uncommon relative to HAV.

journal_name

J Med Virol

authors

Bernal W,Smith HM,Williams R

doi

10.1002/(SICI)1096-9071(199607)49:3<230::AID-JMV12

subject

Has Abstract

pub_date

1996-07-01 00:00:00

pages

230-4

issue

3

eissn

0146-6615

issn

1096-9071

pii

10.1002/(SICI)1096-9071(199607)49:3<230::AID-JMV12

journal_volume

49

pub_type

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