A natural inter-genotypic (2b/1b) recombinant of hepatitis C virus in the Philippines.

abstract：:Human polyomaviruses HPyV6, HPyV7, TSPyV, HPyV9, MWPyV, and KIPyV have been discovered between 2007 and 2012. TSPyV causes a rare skin disease trichodysplasia spinulosa in immunocompromised patients, the role of remaining polyomaviruses in human pathology is not clear. In this study, we assessed the occurrence of seru...

journal_title：Journal of medical virology

authors： Šroller V,Hamšíková E,Ludvíková V,Musil J,Němečková Š,Saláková M

更新日期：2016-07-01 00:00:00

abstract：:Herpes zoster is a common infectious disease that can result in significant acute and chronic morbidity. The safety and efficacy of once-daily oral valomaciclovir (EPB-348) was evaluated for non-inferiority to 3-times daily valacyclovir, an approved therapy. In this study, 373 immunocompetent adults with onset of a he...

journal_title：Journal of medical virology

authors： Tyring SK,Plunkett S,Scribner AR,Broker RE,Herrod JN,Handke LT,Wise JM,Martin PA,Valomaciclovir Zoster Study Group.

更新日期：2012-08-01 00:00:00

abstract：:Previous studies on patients who develop drug resistant HIV-1 variants have shown that continued use of failing regimens might provide clinical benefit. However, the effect of long-term exposure to drug resistant variants may lead to emergence of compensatory mutations that may jeopardize this effect. In this study, w...

journal_title：Journal of medical virology

authors： Machouf N,Thomas R,Nguyen VK,Trottier B,Boulassel MR,Wainberg MA,Routy JP

更新日期：2006-05-01 00:00:00

abstract：UNLABELLED:Viral respiratory tract infections in lung transplant recipients may be severe. During three consecutive winter-spring seasons, 49 symptomatic lung transplant recipients with suspected respiratory viral infection, and 26 asymptomatic patients were investigated for presence of respiratory viruses either in 56...

journal_title：Journal of medical virology

authors： Gerna G,Vitulo P,Rovida F,Lilleri D,Pellegrini C,Oggionni T,Campanini G,Baldanti F,Revello MG

更新日期：2006-03-01 00:00:00

abstract：:The incidence and the outcome of cytomegalovirus (CMV) infections were evaluated in 83 adult recipients of allogenic bone marrow transplantation. Virological and serological surveillance was performed weekly for 3 months posttransplant, and then every other week or every month until 1 year. CMV infection occurred in 4...

journal_title：Journal of medical virology

authors： Guyotat D,Gibert R,Chomel J,Archimbaud E,Bossard S,Maupas J,Fiere D,Aymard M

更新日期：1987-12-01 00:00:00

abstract：:The emergence of genotypic resistance in protease and reverse transcriptase (RT) gene regions was longitudinally evaluated in plasma samples from a group of 12 HIV-1-infected patients treated with different combination of antiretroviral therapies and selected on the basis of their clinical failure. Complex mutational ...

journal_title：Journal of medical virology

authors： Cabana M,Clotet B,Martínez MA

更新日期：1999-12-01 00:00:00

abstract：:Inoue-Melnick virus (IMV) was stabilized to thermal inactivation at 50 degrees C by 1 M Na2SO4 but not by 1 M MgCl2, 1 M MgSO4, 2 M NaCl, and 2 M KCl. The latter salts enhanced the inactivation over that in distilled water. Na2SO4 stabilized IMV at 1 M concentration but enhanced inactivation at 0.1 M. Three types of I...

journal_title：Journal of medical virology

authors： Nishibe Y,Inoue YK,Melnick JL

更新日期：1986-10-01 00:00:00

abstract：:The contribution of viruses to lower respiratory tract disease in sub-Saharan Africa where human immunodeficiency virus may exacerbate respiratory infections is not well defined. No data exist on some of these viruses for Southern Africa. Comprehensive molecular screening may define the role of these viruses as single...

journal_title：Journal of medical virology

authors： Venter M,Lassaunière R,Kresfelder TL,Westerberg Y,Visser A

更新日期：2011-08-01 00:00:00

abstract：:A total of 18 rotavirus G9 strains in South Korea were collected during five rotavirus seasons between 2005 and 2010. The relationship between these strains was examined by analyzing the genetic variation of two major structural genes, VP7 and VP4. All the rotavirus isolates were of the G9P[8] genotype. The VP7 phylog...

journal_title：Journal of medical virology

authors： Than VT,Kang H,Lim I,Kim W

更新日期：2013-01-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) circulating recombinant form (CRF) 07_BC strain has caused serious outbreaks among injection drug users in Taiwan since 2004. The objective of this study was to conduct a molecular epidemiological study of HCV genotypes in intravenous drug users in Taiwan. Blood samples and ...

journal_title：Journal of medical virology

authors： Lee YM,Lin HJ,Chen YJ,Lee CM,Wang SF,Chang KY,Chen TL,Liu HF,Chen YM

更新日期：2010-01-01 00:00:00

abstract：:A highly sensitive two-step polymerase chain reaction (PCR) method was evaluated for detection of human immunodeficiency virus type 1 (HIV-1) DNA in clinical specimens. The product resulting from the first amplification reaction is used as the template for the second PCR with an internal (nested) primer pair. Even whe...

journal_title：Journal of medical virology

authors： Zazzi M,Romano L,Brasini A,Valensin PE

更新日期：1992-11-01 00:00:00

abstract：:Dual infection with hepatitis B and C viruses is often encountered in endemic areas of both viruses. However, understanding of the clinical and virological implications is limited. The aim of this study was to investigate the role of each virus in liver injury and the interaction between the two viruses in dual infect...

journal_title：Journal of medical virology

authors： Ohkawa K,Hayashi N,Yuki N,Masuzawa M,Kato M,Yamamoto K,Hosotsubo H,Deguchi M,Katayama K,Kasahara A

更新日期：1995-07-01 00:00:00

abstract：:Serial serum samples from 20 untreated patients with chronic hepatitis C virus (HCV) infection were tested for HCV RNA by a nested polymerase chain reaction assay using primers from the highly conserved 5' noncoding region to determine the relationship between hepatitis C viremia and the activity of liver disease duri...

journal_title：Journal of medical virology

authors： Cheung RC,Chan RT,Lok AS

更新日期：1993-12-01 00:00:00

abstract：:A total of 190 specimens from South Indian children aged 0-59 months with ocular anomalies consistent with suspected congenital rubella syndrome (CRS) were investigated. Twenty-six of the 65 infants (40%) were confirmed as CRS by detection of rubella specific IgM. Rubella RNA was detected in 41 samples from 26 infants...

journal_title：Journal of medical virology

authors： Rajasundari TA,Sundaresan P,Vijayalakshmi P,Brown DW,Jin L

更新日期：2008-03-01 00:00:00

abstract：:Although neutralizing antibodies against Hantaan virus (HTV) can protect hosts from viral infection, T-cell responses to HTV are also important in host defense against HTV. However, much less is known about cytotoxic T lymphocyte (CTL) responses to HTV. To identify CTL epitopes in the HTV nucleocapsid protein (NP), we...

journal_title：Journal of medical virology

authors： Park JM,Cho SY,Hwang YK,Um SH,Kim WJ,Cheong HS,Byun SM

更新日期：2000-02-01 00:00:00

abstract：:Mutations of the precore region of hepatitis B virus (HBV) genome have been associated with fulminant and severe chronic hepatitis. However uncertainty remains about the clinical significance and transmissibility of these mutant strains. A point mutation assay (PMA) was developed to identify qualitatively and quantita...

journal_title：Journal of medical virology

authors： Hawkins AE,Gilson RJ,Beath SV,Boxall EH,Kelly DA,Tedder RS,Weller IV

更新日期：1994-09-01 00:00:00

abstract：:It has been reported that low-plasma cytomegalovirus (CMV) DNA loads are associated with an increased risk of overall mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Utilizing a conservative strategy for initiation of preemptive antiviral therapy (>1500 IU/mL), we characterized the virolog...

journal_title：Journal of medical virology

authors： Talaya A,Giménez E,Piñana JL,Albert E,Hernández-Boluda JC,Pérez A,Torres I,Solano C,Navarro D

更新日期：2019-06-01 00:00:00

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine with pivotal functions in the regulation of the biological responses of several target cells, including hepatocytes. Previous studies have shown that serum IL-6 levels are increased in hepatitis B patients. However, the role of IL-6 in modulating the anti-hepatitis B viru...

journal_title：Journal of medical virology

authors： Yang K,Guan S,Zhang H,Chen Z

更新日期：2019-05-01 00:00:00

abstract：:This study aimed to examine the application of hepatitis B surface antigen (HBsAg) confirmatory testing when diagnosing hepatitis B infection among young persons in Taiwan with a low prevalence rate of hepatitis B infection. HBsAg status, the presence of antibodies against HBsAg (anti-HBs), and the presence of antibod...

journal_title：Journal of medical virology

authors： Chu FY,Su FH,Cheng SH,Lin YS,Li CY,Chien CC,Lin YC,Chiang SY

更新日期：2011-09-01 00:00:00

abstract：:During 1999-2000, a sustained mumps outbreak in the highly vaccinated population in Singapore was attributed to vaccine failure associated with the Rubini vaccine strain. To explain this phenomenon, the complete nucleotide and amino acid sequences of the hemagglutinin-neuraminidase (HN) gene of eight mumps virus isola...

journal_title：Journal of medical virology

authors： Lim CS,Chan KP,Goh KT,Chow VT

更新日期：2003-06-01 00:00:00

abstract：:In this study, recombinant hemagglutinin protein (rH1N1HA) of Pandemic influenza virus and polyclonal antibodies against it for biosensor applications have been characterized. For rapid and high sensitive detection of H1N1 virus or its antibodies, PCR-free and label free detection method based on a surface plasmon res...

journal_title：Journal of medical virology

authors： Athmaram TN,Saraswat S,Sikarwar B,Verma SK,Singh AK,Boopathi M

更新日期：2014-03-01 00:00:00

abstract：:Noroviruses (NoVs) are a leading cause of acute gastroenteritis outbreaks and sporadic cases of diarrhea in industrialized countries. To study the prevalence and genetic diversity of NoVs in Guatemala, stool specimens were collected from hospitalized and ambulatory patients presenting with diarrhea (≥3 loose or liquid...

journal_title：Journal of medical virology

authors： Estévez A,Arvelo W,Hall AJ,López MR,López B,Reyes L,Moir JC,Gregoricus N,Vinjé J,Parashar UD,Lindblade KA

更新日期：2013-07-01 00:00:00

abstract：:To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok...

journal_title：Journal of medical virology

authors： Li X,Zai J,Wang X,Li Y

更新日期：2020-04-01 00:00:00

abstract：:Using the RT-PCR with primers that anneal to the 5' and the 3' extremities of the genome segments of bunyaviruses and internal primers that anneal to the S segment of Simbu serogroup viruses in a nested PCR it was possible to amplify the Oropouche virus (ORO) genome from the sera of three patients. These results show ...

journal_title：Journal of medical virology

authors： Moreli ML,Aquino VH,Cruz AC,Figueiredo LT

更新日期：2002-01-01 00:00:00

abstract：:Although risk factors for cirrhosis in chronic hepatitis C virus (HCV) infection have been identified, the role of HCV-genotype 3 remains controversial, and limited data are available in drug users. The aim of the study was to assess risk factors for severe liver disease (cirrhosis/hepatocellular carcinoma) in HCV-inf...

journal_title：Journal of medical virology

authors： Larsen C,Bousquet V,Delarocque-Astagneau E,Pioche C,Roudot-Thoraval F,HCV Surveillance Steering Committee.,HCV Surveillance Group.,Desenclos JC

更新日期：2010-10-01 00:00:00

abstract：:GB virus-B (GBV-B) is the virus most closely related to hepatitis C virus (HCV). Thus, we have used GBV-B infection of tamarins, which develop acute hepatitis following experimental infection, as a surrogate model to study protective immunity. As challenge virus, we first produced a GBV-B pool from an infected tamarin...

journal_title：Journal of medical virology

authors： Bukh J,Engle RE,Govindarajan S,Purcell RH

更新日期：2008-01-01 00:00:00

abstract：:Infection with the human cytomegalovirus (HCMV) accelerates disease progression in human immunodeficiency virus 1 (HIV-1)-infected individuals. This has been attributed to the transaction of HIV-1 gene expression by HCMV gene products. For transactivation to be effective in vivo both viruses must be present in the sam...

journal_title：Journal of medical virology

authors： Bertram S,Hufert FT,van Lunzen J,von Laer D

更新日期：1996-08-01 00:00:00

abstract：:Alkali-dissociated, purified preparations of prototype coxsackievirus B4 release a protein kinase that catalyzes the incorporation of gamma-phosphate from 32P-labeled ATP into three virus capsid proteins (VP1, VP3, VP4), several additional proteins of the particle, and exogenous acceptor proteins. Using protamine sulf...

journal_title：Journal of medical virology

authors： Chatterjee NK,Nejman C

更新日期：1986-08-01 00:00:00

abstract：:Sexually transmitted disease (STD) remains a major public health challenge in developed countries, exacerbated by the advent of the HIV epidemic. The objectives of this study were to assess the prevalence of serological markers of syphilis, HIV-1/2, HTLV-I/II, HBV, and HCV infections among immigrant sex workers in Mad...

journal_title：Journal of medical virology

authors： Gutiérrez M,Tajada P,Alvarez A,De Julián R,Baquero M,Soriano V,Holguín A

更新日期：2004-12-01 00:00:00

abstract：:Screening for high-risk human papillomavirus (HPV) types allows the detection of women at a high risk of cervical squamous carcinomas, thereby defining a subset of patients targeted for more intensive screening and follow-up. Thirty-four cervical biopsy specimens and isolated cells from cervical smears of normal women...

journal_title：Journal of medical virology

authors： Adams V,Moll C,Schmid M,Rodrigues C,Moos R,Briner J

更新日期：1996-02-01 00:00:00