High prevalence of TT virus-related DNA (90%) and diverse viral genotypes in Norwegian blood donors.

Abstract:

:Early estimates of the prevalence of TTV viremia in healthy adults of developed countries were in the order of 1--10 %, while similar estimates in Third World countries were considerably higher. Using three different PCRs, TTV-related DNA was detected in serum from 180 out of the 201 Norwegian blood donors tested, indicating that these viruses are almost universally present in adults. Sequence analysis revealed heterogeneity similar to what is found world-wide. The data suggest that the previous discrepancy in prevalences might be related to a lower serum concentration of virus in developed countries. The high prevalence adds evidence to the benign nature of the virus.

journal_name

J Med Virol

authors

Huang LY,Oystein Jonassen T,Hungnes O,Grinde B

doi

10.1002/jmv.1062

keywords:

subject

Has Abstract

pub_date

2001-07-01 00:00:00

pages

381-6

issue

3

eissn

0146-6615

issn

1096-9071

pii

10.1002/jmv.1062

journal_volume

64

pub_type

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