9-Nitrocamptothecin inhibits HIV-1 replication in human peripheral blood lymphocytes: a potential alternative for HIV-infection/AIDS therapy.

abstract：:Rotavirus-specific subclass antibody responses and cytokines, tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-8 (IL-8), and IL-10, were measured in children 7-24 months of age with rotavirus diarrhoea (n = 29); the responses were compared with children with watery diarrhoea from who...

journal_title：Journal of medical virology

authors： Azim T,Zaki MH,Podder G,Sultana N,Salam MA,Rahman SM,Sefat-e-Khuda,Sack DA

更新日期：2003-02-01 00:00:00

abstract：:Hepatitis C virus (HCV), exhibits considerable genetic diversity, but presents a relatively well conserved 5' noncoding region (5' NCR) among all genotypes. In this study, the structural features and translational efficiency of the HCV 5' NCR sequences were analyzed using the programs RNAfold, RNAshapes and RNApdist a...

journal_title：Journal of medical virology

authors： Araújo FM,Machado-Lima A,Durham AM,Teixeira R,Oliveira G

更新日期：2009-07-01 00:00:00

abstract：:Oral DAA have demonstrated high efficacy as treatment of hepatitis C. However, the presence of resistance-associated substitutions (RAS) at baseline has occasionally been associated with impaired treatment response. Herein, we examined the impact of baseline RAS at the HCV NS5A gene region on treatment response in a r...

journal_title：Journal of medical virology

authors： Carrasco I,Arias A,Benítez-Gutiérrez L,Lledó G,Requena S,Cuesta M,Cuervas-Mons V,de Mendoza C

更新日期：2018-03-01 00:00:00

abstract：:Incarcerated persons have high rates of infectious diseases. Few data on the prevalence of sexually transmitted diseases in prisoners are available. This multi-center cross-sectional study enrolled 973 inmates from eight Italian prisons. Demographic and behavioral data were collected using an anonymous standardized qu...

journal_title：Journal of medical virology

authors： Sarmati L,Babudieri S,Longo B,Starnini G,Carbonara S,Monarca R,Buonomini AR,Dori L,Rezza G,Andreoni M,Gruppo di Lavoro Infettivologi Penitenziari (GLIP).

更新日期：2007-02-01 00:00:00

abstract：:Infection with oncogenic human papillomavirus (HPV) genotypes is necessary for the development of cervical cancer. Testing for HPV DNA from liquid based cervical samples can be used as an adjunct to traditional cytological screening. In addition there are ongoing viral load, genotyping, and prevalence studies. Therefo...

journal_title：Journal of medical virology

authors： Brestovac B,Wong ME,Costantino PS,Groth D

更新日期：2014-04-01 00:00:00

abstract：:Lymphocytic choriomeningitis virus (LCMV), which is one of several arenaviruses that are pathogenic for humans, causes encephalitis and meningitis in man. In this study, single-stage and nested reverse transcription-polymerase chain reaction (RT-PCR) assays were developed that targeted the GPC and N genes of LCMV. Bot...

journal_title：Journal of medical virology

authors： Park JY,Peters CJ,Rollin PE,Ksiazek TG,Gray B,Waites KB,Stephensen CB

更新日期：1997-02-01 00:00:00

abstract：:Genetically different subpopulations were identified and purified from Japanese Encephalitis virus (JEV). Those with small plaques (SPs; <2 mm in diameter), derived from strains of T1P1, CJN, and CC27, were more competent than those with large plaques (LPs; >5 mm in diameter) when passaged in Neuro-2a cells. Differenc...

journal_title：Journal of medical virology

authors： Chiou SS,Liu H,Chuang CK,Lin CC,Chen WJ

更新日期：2005-08-01 00:00:00

abstract：:Anal cancer is a rare disease. Nevertheless, it may be a reason for concern among groups in which its incidence is increasing: those who engage in anoreceptive intercourse, promiscuous persons, and those with sexually transmitted infections (HPV and HIV). The aim of this study was to evaluate the prevalence of abnorma...

journal_title：Journal of medical virology

authors： Chaves EB,Folgierini H,Capp E,von Eye Corleta H

更新日期：2012-09-01 00:00:00

abstract：:The discovery of acyclovir marked the beginning of an exciting era in antiviral research. Early studies on the novel mode of action explained the selectivity of the compound and the remarkably narrow spectrum of activity against a subset of the herpesviruses. Throughout the past decade many clinical trials have demons...

journal_title：Journal of medical virology

authors： Darby G

更新日期：1993-01-01 00:00:00

abstract：:In October 1977 an outbreak of acute infectious diarrhea occurred in an infant home in the city of Sapporo, Japan. Of 34 residents aged two to 20 months, 26 (77%) suffered from diarrhea. In ten of these patients the diarrhea was accompanied by vomiting. Electron microscopic examinations revealed typical calicivirus pa...

journal_title：Journal of medical virology

authors： Chiba S,Sakuma Y,Kogasaka R,Akihara M,Horino K,Nakao T,Fukui S

更新日期：1979-01-01 00:00:00

abstract：:The reliability of the polymerase chain reaction (PCR) for prenatal diagnosis of human cytomegalovirus (HCMV) infection was determined by retrospective testing of 35 amniotic fluids identified previously as positive or negative for HCMV by virus isolation. Amniocentesis was performed in 26 pregnant women with primary ...

journal_title：Journal of medical virology

authors： Revello MG,Baldanti F,Furione M,Sarasini A,Percivalle E,Zavattoni M,Gerna G

更新日期：1995-12-01 00:00:00

abstract：:Herpes simplex virus can be quantitatively recovered from vaginal tampons suspended in tissue culture medium and stored over a wide range of temperatures. Because herpes simplex virus is stable for several days with refrigeration or after freezing, this method of culture of cervicovaginal virus lends itself to epidemi...

journal_title：Journal of medical virology

authors： Myers MG,Ekwo EE,Pitts AK

更新日期：1979-01-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) of peripheral blood mononuclear cells (PBMCs) collected from Human immunodeficiency virus 1 (HIV-1)-infected patients and healthy controls were measured longitudinally using real-time polymerase chain reaction to evaluate the effects of antiretroviral agents on mtDNA synthesis in vivo and to ...

journal_title：Journal of medical virology

authors： Miura T,Goto M,Hosoya N,Odawara T,Kitamura Y,Nakamura T,Iwamoto A

更新日期：2003-08-01 00:00:00

abstract：:In this meta-analysis, we evaluated the diagnostic role of Epstein-Barr virus deoxyribonucleic acid detection and quantitation in the serum of pediatric and young adult patients with infectious mononucleosis. The primary outcome of this meta-analysis was the sensitivity and specificity of Epstein-Barr virus (EBV) deox...

journal_title：Journal of medical virology

authors： Jiang SY,Yang JW,Shao JB,Liao XL,Lu ZH,Jiang H

更新日期：2016-05-01 00:00:00

abstract：:Despite prolonged undetectable plasma viral load some HIV-1 infected patients have been reported to develop resistance-associated mutations leading to treatment failure. The mechanisms for this phenomenon and the point of origin for residual viral evolution are still not elucidated. In order to quantify cell-associate...

journal_title：Journal of medical virology

authors： Kupfer B,Matz B,Däumer MP,Roden F,Rockstroh JK,Qurishi N,Spengler U,Kaiser R

更新日期：2007-10-01 00:00:00

abstract：:Latency associated peptide (LAP) is a protein expressed on the membrane of some regulatory T cells (Treg). LAP+ Treg have a greater immunomodulatory effect than that of their negative counterparts. In this study, we presented the data on the proportion of LAP+ Treg out of CD4+ cells in mice with viral myocarditis, whi...

journal_title：Journal of medical virology

authors： Wang X,Ge J,Chen R

更新日期：2019-05-01 00:00:00

abstract：:Overall, head and neck sqamous cell carcinoma accounts for more than 550,000 cases annually worldwide. It is well known that human papillomavirus (HPV) is the main risk factor for cervical cancer development. As the incidence and the mortality of cervical cancer are closely related to the HPV prevalence, we hypothesiz...

journal_title：Journal of medical virology

authors： Gudleviciene Z,Didziapetriene J,Mackeviciene I,Cicenas S,Smolyakova R,Zhukavetc A

更新日期：2014-03-01 00:00:00

abstract：:Although many reports have already shown RSV outbreaks among hemato-oncology patients, genomic studies detecting similar RSV strains prior to an outbreak in the hospital are rare. In 2014, the University of the Ryukyus hospital hemato-oncology unit experienced, and successfully managed, a respiratory syncytial virus (...

journal_title：Journal of medical virology

authors： Nabeya D,Kinjo T,Parrott GL,Uehara A,Motooka D,Nakamura S,Nahar S,Nakachi S,Nakamatsu M,Maeshiro S,Haranaga S,Tateyama M,Tomoyose T,Masuzaki H,Horii T,Fujita J

更新日期：2017-08-01 00:00:00

abstract：:Ideally, long-term lamivudine therapy should not induce tyrosine-methionine-aspartate-aspartate (YMDD) mutants (reverse transcription [rt]; rt M204I/V) in patients with chronic hepatitis B. There is little or no information on the clinical features of patients who do not develop such mutants. We analyzed 368 patients ...

journal_title：Journal of medical virology

authors： Hashimoto Y,Suzuki F,Hirakawa M,Kawamura Y,Yatsuji H,Sezaki H,Hosaka T,Akuta N,Kobayashi M,Saito S,Suzuki Y,Kobayashi M,Arase Y,Ikeda K,Kumada H

更新日期：2010-04-01 00:00:00

abstract：:This study aimed to examine the baseline prevalence of genital human papillomavirus (HPV) infection among human immunodeficiency virus (HIV)-seropositive men who have sex with men in Taiwan and to determine the association of age and CD4+ T cell counts with HPV infection. In 2010, 305 men who have sex with men infecte...

journal_title：Journal of medical virology

authors： Cheng SH,Chu FY,Lin YS,Hsueh YM

更新日期：2012-12-01 00:00:00

abstract：:Therapy failure due to drug resistance development is a common phenomenon in HIV-infected patients. However, when the drug pressure leads to the earliest selection of drug-resistant HIV-1 populations is still unclear. In this study, the extent to which selection of the HIV-1 reverse transcriptase M184I/V mutations occ...

journal_title：Journal of medical virology

authors： Bergroth T,Ekici H,Gisslén M,Loes SK,Goh LE,Freedman A,Lampe F,Johnson MA,Sönnerborg A

更新日期：2009-01-01 00:00:00

abstract：:Little information about immunity to respiratory syncytial virus (RSV) and disease pathogenesis in elderly persons exists. Humoral immunity to RSV was assessed in 41 young, 56 healthy elderly, and 49 frail elderly adults by measuring baseline RSV specific IgG by enzyme immunoassay (EIA) and microneutralization assay (...

journal_title：Journal of medical virology

authors： Falsey AR,Walsh EE,Looney RJ,Kolassa JE,Formica MA,Criddle MC,Hall WJ

更新日期：1999-10-01 00:00:00

abstract：:The performance of French virology laboratories belonging to the ANRS network has been assessed annually for 3 years. The performance of these laboratories was compared between the years 2002 and 2003. Ten and 7 coded samples were sent to 38 virology laboratories in 2002 and 45 virology laboratories in 2003, respectiv...

journal_title：Journal of medical virology

authors： Descamps D,Delaugerre C,Masquelier B,Ruffault A,Marcelin AG,Izopet J,Chaix ML,Calvez V,Brun-Vézinet F,Costagliola D

更新日期：2006-02-01 00:00:00

abstract：:Many of the small round human fecal viruses implicated in outbreaks of nonbacterial gastroenteritis have been collected together and examined under the electron microscope. Negatively stained preparations without the addition of antibody were used so that the surface morphology of the virus particles remained clearly ...

journal_title：Journal of medical virology

authors： Caul EO,Appleton H

更新日期：1982-01-01 00:00:00

abstract：:The infection of enterovirus 71 (EV71) resulted in hand, foot, and mouth disease and may lead to severe nervous system damage and even fatalities. There are no effective drugs to treat the EV71 virus and it is crucial to find novel drugs against it. Polysaccharide isolated from Durvillaea antarctica green algae has an...

journal_title：Journal of medical virology

authors： Xu T,Li Y,Wu HL,Chen H,Wu H,Guo M,Zhao M,Wang C,Lin T,Lin Z,Chen D,Xiang W,Zhu B

更新日期：2020-11-24 00:00:00

abstract：:Virological studies were carried out on 3 to 36-month-old patients admitted to the Children's Hospital of the University of Modena with febrile syndrome from September 1990 to February 1991. Virological tests were carried out for human herpesvirus-6 (HHV-6), Epstein-Barr virus (EBV), cytomegalovirus (CMV), herpes simp...

journal_title：Journal of medical virology

authors： Portolani M,Cermelli C,Moroni A,Bertolani MF,Di Luca D,Cassai E,Sabbatini AM

更新日期：1993-02-01 00:00:00

abstract：:Palatine tonsils have been observed to harbor several distinct respiratory and herpesviruses in separate studies. In this study, the presence of these viruses in palatine tonsils was comprehensively studied in both children and adults. A cross-sectional analysis of 181 patients (median age 22 years; range, 2.6-66) ope...

journal_title：Journal of medical virology

authors： Silvoniemi A,Mikola E,Ivaska L,Jeskanen M,Löyttyniemi E,Puhakka T,Vuorinen T,Jartti T

更新日期：2020-06-30 00:00:00

abstract：:Fifty-three (96%) of 55 patients with coronary artery stenosis were positive for serum anti-HHV-6 IgG, and 50 (91%) of these patients had anti-HHV-7 IgG. The number of cases sero-positive for HHV-6 and -7 in the 54 age matched control volunteers was 52 (96%) and 53 (98%), respectively. No statistical difference in the...

journal_title：Journal of medical virology

authors： Ihira M,Yoshikawa T,Ishii J,Nomura M,Hishida H,Ohashi M,Enomoto Y,Suga S,Iida K,Saito Y,Nishiyama Y,Asano Y

更新日期：2002-08-01 00:00:00

abstract：:Persistent infection with high-risk human papillomavirus (HPV) causes cervical preneoplasic lesions and invasive cervical cancer. This study evaluated the prevalence and distribution of HPV genotypes in cervical exfoliated cells from Uruguayan women. Five hundred sixty-eight cervical specimens were examined by PCR usi...

journal_title：Journal of medical virology

authors： Ramas V,Mirazo S,Bonilla S,Mendoza L,Lago O,Basiletti J,González J,Picconi MA,Arbiza J

更新日期：2013-05-01 00:00:00

abstract：:Virus fragments homologous to TTV were detected previously from an enterically transmitted outbreak of non-A-E hepatitis [Luo et al., 1999]. To test the susceptibility of the Rhesus monkey to this virus and to establish its transmission routes, 6 Rhesus monkeys were inoculated, 3 orally and another 3 intravenously. Th...

journal_title：Journal of medical virology

authors： Luo K,Liang W,He H,Yang S,Wang Y,Xiao H,Liu D,Zhang L

更新日期：2000-05-01 00:00:00