Human papillomavirus genotypes distribution in cervical samples from Uruguayan women.

Abstract:

:Persistent infection with high-risk human papillomavirus (HPV) causes cervical preneoplasic lesions and invasive cervical cancer. This study evaluated the prevalence and distribution of HPV genotypes in cervical exfoliated cells from Uruguayan women. Five hundred sixty-eight cervical specimens were examined by PCR using MY09/11 primer set, and were genotyped by restriction enzyme digestion (RFLP). Some of the samples which remained undetermined were reanalyzed by PGMY PCR combined with reverse line blot hybridization. Overall, about 42% of samples were positive for HPV; 96% in high-grade squamous intraepithelial lesion, 66% in low-grade squamous intraepithelial lesion, 15% in atypical squamous cells of undetermined significance, and 19% in samples negative for intraepithelial lesion or malignancy. HPV 16 was the most commonly found genotype, followed by HPV 68 and 58. Within low risk-HPV genotypes 6, 61, and 11 were the most frequent. This is the first cross-sectional study, accounting for prevalence and genotype distribution of HPV in Uruguayan women.

journal_name

J Med Virol

authors

Ramas V,Mirazo S,Bonilla S,Mendoza L,Lago O,Basiletti J,González J,Picconi MA,Arbiza J

doi

10.1002/jmv.23479

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

845-51

issue

5

eissn

0146-6615

issn

1096-9071

journal_volume

85

pub_type

杂志文章
  • HBeAg-negative chronic hepatitis patients should be monitored more strictly: a cross-sectional retrospective study on antiviral treatment-naïve patients.

    abstract:AIM:To investigate the prevalence and characteristics of hepatitis B e antigen (HBeAg) negative/treatment naïve subjects with low hepatitis B virus (HBV) DNA levels (<10(4)  copies/ml) and low alanine aminotransferase (ALT) levels (<2 × upper limit of normal) in patients with HBV-related hepatocellular carcinoma (HCC)....

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24217

    authors: Zeng DW,Dong J,Zhang JM,Zhu YY,Jiang JJ,Liu YR

    更新日期:2015-10-01 00:00:00

  • Lack of effect of a booster dose of influenza vaccine in hemodialysis patients.

    abstract::To assess whether the administration of a booster dose of influenza vaccine may enhance immune response in hemodialysis patients, 58 subjects were given two doses of the 2003/2004 season influenza vaccine, 1 month apart. "European Agency for the Evaluation of Medicinal Products" (EMEA) criteria were fully met in terms...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20936

    authors: Tanzi E,Amendola A,Pariani E,Zappa A,Colzani D,Logias F,Perego A,Zanetti AR

    更新日期:2007-08-01 00:00:00

  • Genetic characterization of measles viruses that circulated in Thailand from 1998 to 2008.

    abstract::During the period between 1998 and 2008, 48 representative measles viruses (MeVs) circulating in Thailand were subjected to genetic characterization. Three genotypes, G2, D5, and D9 were detected. The results suggested that measles genotype D5, which has been circulating since at least 1998, is the endemic genotype in...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23249

    authors: Pattamadilok S,Incomserb P,Primsirikunawut A,Lukebua A,Rota PA,Sawanpanyalert P

    更新日期:2012-05-01 00:00:00

  • Human papillomavirus type 11 neutralization in the athymic mouse xenograft system: correlation with virus-like particle IgG concentration.

    abstract::Neutralization of virus is likely to be necessary for development of an effective prophylactic vaccine against genital human papillomavirus (HPV) infection. Two New Zealand white rabbits were immunized with purified HPV type 11 (HPV 11) virions in Freund's adjuvant. An enzyme linked immunoassay (ELISA) was used to det...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199711)53:3<185::aid-jmv1>

    authors: Bryan JT,Jansen KU,Lowe RS,Fife KH,McClowry T,Glass D,Brown DR

    更新日期:1997-11-01 00:00:00

  • Molecular characterization of group A rotavirus found in elderly patients in Ireland; predominance of G1P[8], continued presence of G9P[8], and emergence of G2P[4].

    abstract::Rotavirus is a major cause of gastroenteritis in young children worldwide. There have been several recent reports concerning rotavirus isolation from adults, particularly in the elderly, presenting with gastroenteritis. In this study, the authors report on rotavirus outbreaks in five separate elderly care facilities b...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23416

    authors: Gunn L,Feeney SA,Cashman O,Collins PJ,Coyle PV,O'Shea H

    更新日期:2012-12-01 00:00:00

  • Comprehensive investigation of the presence of JC virus in AIDS patients with and without progressive multifocal leukoencephalopathy.

    abstract::Progressive multifocal leukoencephalopathy (PML), a viral-induced demyelinating disease, is becoming relatively common, while many diagnostic and pathogenetic aspects remain to be clarified. A study was therefore undertaken in 64 AIDS patients suffering from various neurological disorders, including PML (12 subjects),...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199707)52:3<235::aid-jmv1>

    authors: Ferrante P,Caldarelli-Stefano R,Omodeo-Zorini E,Cagni AE,Cocchi L,Suter F,Maserati R

    更新日期:1997-07-01 00:00:00

  • Importance of endothelial dysfunction biomarkers in patients with Crimean-Congo hemorrhagic fever.

    abstract::The pathogenesis of the Crimean-Congo hemorrhagic fever (CCHF) and the cause of the hemorrhage are not yet fully understood. However, the endothelium plays a key role in the pathogenesis. The purpose of this study was to investigate endothelial dysfunction markers (asymmetrical dimethyl arginine [ADMA], endothelin 1[E...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24881

    authors: Arslan M,Yilmaz G,Mentese A,Yilmaz H,Karahan SC,Koksal I

    更新日期:2017-12-01 00:00:00

  • Incidence and prognosis of cytomegalovirus infections following allogenic bone marrow transplantation.

    abstract::The incidence and the outcome of cytomegalovirus (CMV) infections were evaluated in 83 adult recipients of allogenic bone marrow transplantation. Virological and serological surveillance was performed weekly for 3 months posttransplant, and then every other week or every month until 1 year. CMV infection occurred in 4...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890230412

    authors: Guyotat D,Gibert R,Chomel J,Archimbaud E,Bossard S,Maupas J,Fiere D,Aymard M

    更新日期:1987-12-01 00:00:00

  • Lineage analysis of human papillomavirus type 18 based on E6 region in cervical samples of Iranian women.

    abstract::Distinct human papillomavirus (HPV) 18 variants are thought to differ in oncogenic potential and geographic distribution. As such, understanding the regional variants of HPV 18 would be of great importance for evolutionary, epidemiological, and biological analysis. In this regard, the sequence variations of E6 gene we...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26283

    authors: Salavatiha Z,Shoja Z,Heydari N,Marashi SM,Younesi S,Nozarian Z,Jalilvand S

    更新日期:2020-07-09 00:00:00

  • Prevalence of human papillomaviruses in patients with head and neck squamous cell carcinoma in Lithuania and Belarus.

    abstract::Overall, head and neck sqamous cell carcinoma accounts for more than 550,000 cases annually worldwide. It is well known that human papillomavirus (HPV) is the main risk factor for cervical cancer development. As the incidence and the mortality of cervical cancer are closely related to the HPV prevalence, we hypothesiz...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23750

    authors: Gudleviciene Z,Didziapetriene J,Mackeviciene I,Cicenas S,Smolyakova R,Zhukavetc A

    更新日期:2014-03-01 00:00:00

  • Combinations of 1,8-cineol and oseltamivir for the treatment of influenza virus A (H3N2) infection in mice.

    abstract::It is need for development of new means against influenza virus due to the lack of efficacy of available therapeutic strategies. In previous research, 1,8-cineol exert its inhibition of nuclear factor (NF)-κB, the main regulator of cytokine and chemokine production in influenza, and anti-inflammatory activity. These f...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24755

    authors: Lai YN,Li Y,Fu LC,Zhao F,Liu N,Zhang FX,Xu PP

    更新日期:2017-07-01 00:00:00

  • Dysregulation of the immune response affects the outcome of critical COVID-19 patients.

    abstract::Critical cases of coronavirus disease 2019 (COVID-19) are associated with a high risk of mortality. It remains unclear why patients with the same critical condition have different outcomes. We aimed to explore relevant factors that may affect the prognosis of critical COVID-19 patients. Six critical COVID-19 inpatient...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26181

    authors: Wei LL,Wang WJ,Chen DX,Xu B

    更新日期:2020-11-01 00:00:00

  • HBeAg and anti-HBe detection by radioimmunoassay: correlation with vertical transmission of hepatitis B virus in Taiwan.

    abstract::A sensitive radioimmunoassay technique was used to detect hepatitis B e antigen (HBeAg). A strong correlation was found between HBeAg positivity of the serum of hepatitis B surface antigen (HBsAg) carrier women in Taiwan and the subsequent development of surface antigenemia in their babies. All babies who became chron...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890030310

    authors: Stevens CE,Neurath RA,Beasley RP,Szmuness W

    更新日期:1979-01-01 00:00:00

  • Low-level plasma HIVs in patients on prolonged suppressive highly active antiretroviral therapy are produced mostly by cells other than CD4 T-cells.

    abstract::The cellular source(s) and the clinical significance of persistent low-level viremia, below 50 HIV RNA copies per ml of plasma, achieved in many patients with high adherence to highly active antiretroviral therapy (HAART) remain unclear. Also, it is not clear if residual plasma HIVs during HAART can become predominant...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21366

    authors: Sahu GK,Paar D,Frost SD,Smith MM,Weaver S,Cloyd MW

    更新日期:2009-01-01 00:00:00

  • Analyzing situational awareness through public opinion to predict adoption of social distancing amid pandemic COVID-19.

    abstract::COVID-19 pandemic has affected over 100 countries in a matter of weeks. People's response toward social distancing in the emerging pandemic is uncertain. In this study, we evaluated the influence of information (formal and informal) sources on situational awareness of the public for adopting health-protective behavior...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25840

    authors: Qazi A,Qazi J,Naseer K,Zeeshan M,Hardaker G,Maitama JZ,Haruna K

    更新日期:2020-07-01 00:00:00

  • Adenoviruses in faeces of children with acute gastroenteritis in Rio de Janeiro, Brazil.

    abstract::Faeces from 746 children less than 5 years old with acute gastroenteritis were screened for the presence of adenovirus particles or antigens by immunoelectron microscopy (IEM) and enzyme immunoassay (EIA). Thirty-five samples were positive by both IEM and EIA, two only by IEM, and two only by EIA, giving a total of 39...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890150213

    authors: Leite JP,Pereira HG,Azeredo RS,Schatzmayr HG

    更新日期:1985-02-01 00:00:00

  • Amino acid substitutions in the hepatitis C virus core region of genotype 1b are the important predictor of severe insulin resistance in patients without cirrhosis and diabetes mellitus.

    abstract::Previous studies provided a direct experimental evidence for the contribution of HCV core protein in the development of insulin resistance (IR), but the clinical impact of HCV core region on IR is still not clear. The present study evaluated the impact of Amino acid (aa) substitutions of HCV-1b core region on IR in 12...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21473

    authors: Akuta N,Suzuki F,Hirakawa M,Kawamura Y,Yatsuji H,Sezaki H,Suzuki Y,Hosaka T,Kobayashi M,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Kumada H

    更新日期:2009-06-01 00:00:00

  • Detection of integrated hepatitis B virus DNA in hepatocellular carcinoma cell lines by nonradioactive in situ hybridization.

    abstract::A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890300407

    authors: Tay N,Chan SH,Ren EC

    更新日期:1990-04-01 00:00:00

  • Diagnosis of enterovirus 70 infection by demonstration of IgM antibodies.

    abstract::Since outbreaks of severe acute hemorrhagic conjunctivitis occur worldwide [Hierholzer and Hatch, 1985] and the majority of the epidemics are caused by enterovirus 70 (EV-70), we developed an EV-70 IgM ELISA to simplify the diagnosis of these outbreaks. The test is based on the capture antibody technique and the use o...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890210404

    authors: Wulff H,Anderson LJ,Pallansch MA,de Souza Carvalho RP

    更新日期:1987-04-01 00:00:00

  • Changes in circulation of B and non-B HIV strains: spotlight on a reference centre for infectious diseases in Northern Italy.

    abstract::Stored demographic data and HIV RT and protease sequences of 877 HIV patients attending for the first time the HIV/AIDS outpatient clinics of a reference Infectious Diseases centre in Northern Italy between 1999 and 2006 were stratified by 3-year spanning periods according to date of HIV infection. In the period 1980-...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21163

    authors: Baldanti F,Paolucci S,Ravasi G,Maccabruni A,Moriggia A,Barbarini G,Maserati R

    更新日期:2008-06-01 00:00:00

  • Genomic and antigenic variation among rotavirus strains circulating in a large city of Argentina.

    abstract::Knowledge of the antigenic diversity of rotaviruses circulating in a region should be acquired before introducing a rotavirus vaccine. In a collection of 151 rotavirus-positive samples from Mendoza, Argentina, strain diversity was evaluated utilizing G-typing monoclonal antibodies (MAbs), reverse-transcriptase-polymer...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Espul C,Cuello H,Martinez N,Centorbi O,O'Ryan M,Jackson L,Campos F,Matson DO

    更新日期:2000-08-01 00:00:00

  • Extended peginterferon alfa-2a (Pegasys) therapy in Chinese patients with HBeAg-negative chronic hepatitis B.

    abstract::The present study compared the efficacy of standard and extended durations of PEG-IFNα-2a monotherapy for treatment of HBeAg-negative Chinese patients with chronic hepatitis B. Patients were randomized to receive standard therapy (n = 38; 48 weeks treatment) or extended therapy (n = 42; 72 weeks treatment). Extended t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/jmv.24013

    authors: Chen X,Chen X,Chen W,Ma X,Huang J,Chen R

    更新日期:2014-10-01 00:00:00

  • Use of recombinant glycoprotein antigens gB and gH for diagnosis of primary human cytomegalovirus infection during pregnancy.

    abstract::The major risk factor for intrauterine transmission of human cytomegalovirus (HCMV) is a primary infection during pregnancy. The neutralizing antibody response appeared after an average of 13 weeks after seroconversion and therefore the absence of neutralizing titers in HCMV IgG positive pregnant women is a reliable m...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Eggers M,Radsak K,Enders G,Reschke M

    更新日期:2001-02-01 00:00:00

  • Serological and molecular prevalence of hepatitis E virus among blood donors from Uruguay.

    abstract::Hepatitis E virus (HEV) infection is considered a neglected disease of major concern in developed countries. Clinically, HEV occurs as an acute and self-limited disease, though chronic cases mostly associated to HEV-3 are now being commonly reported in immunocompromised individuals and solid organ transplant recipient...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26231

    authors: Bangueses F,Abin-Carriquiry JA,Cancela F,Curbelo J,Mirazo S

    更新日期:2020-06-27 00:00:00

  • Carcinogenic ability quantification of human papilloma virus subtypes in eastern China.

    abstract::Human papilloma virus (HPV) infection is a precursor of cervical cancer. This study aimed to introduce a method to quantify the risk of cervical cancer resulting from infection by different HPV subtypes, to help guide patient treatment. Nucleic acid molecule flow-through hybridization and gene chip technology were use...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24280

    authors: Zhu X,Liu H,Wu H,Liu W,Yin L,Sun X

    更新日期:2015-12-01 00:00:00

  • Norovirus infections and seroprevalence of genotype GII.4-specific antibodies in a Spanish population.

    abstract::Genotype II.4 noroviruses (NoVs) are a leading cause of epidemic acute gastroenteritis in children and adults worldwide. The prevalence of different NoV genotypes causing outbreaks and sporadic cases of acute gastroenteritis in the region of Valencia, Spain, during a 4-year period (2008-11) was investigated. NoVs were...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24112

    authors: Carmona-Vicente N,Fernández-Jiménez M,Ribes JM,Téllez-Castillo CJ,Khodayar-Pardo P,Rodríguez-Diaz J,Buesa J

    更新日期:2015-04-01 00:00:00

  • Emergence and genetic evolution of HIV-1 variants with mutations conferring resistance to multiple reverse transcriptase and protease inhibitors.

    abstract::The emergence of genotypic resistance in protease and reverse transcriptase (RT) gene regions was longitudinally evaluated in plasma samples from a group of 12 HIV-1-infected patients treated with different combination of antiretroviral therapies and selected on the basis of their clinical failure. Complex mutational ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199912)59:4<480::aid-jmv10

    authors: Cabana M,Clotet B,Martínez MA

    更新日期:1999-12-01 00:00:00

  • Serum concentrations of ribavirin and pegylated interferon and viral responses in patients infected with HIV and HCV.

    abstract::The hepatitis C virus (HCV) infects a substantial proportion of patients infected with human immunodeficiency virus (HIV). Patients infected with both HCV and HIV respond poorly to anti-HCV treatment with pegylated interferon alpha and ribavirin. But few data are available on the influence of ribavirin and interferon ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21227

    authors: Nicot F,Legrand-Abravanel F,Lafont T,Dubois M,Sauné K,Pasquier C,Chatelut E,Izopet J

    更新日期:2008-09-01 00:00:00

  • Detection and typing of human papillomavirus in biopsy and cytological specimens by polymerase chain reaction and restriction enzyme analysis: a method suitable for semiautomation.

    abstract::Screening for high-risk human papillomavirus (HPV) types allows the detection of women at a high risk of cervical squamous carcinomas, thereby defining a subset of patients targeted for more intensive screening and follow-up. Thirty-four cervical biopsy specimens and isolated cells from cervical smears of normal women...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9071(199602)48:2<161::AID-JMV8>

    authors: Adams V,Moll C,Schmid M,Rodrigues C,Moos R,Briner J

    更新日期:1996-02-01 00:00:00

  • Detection of a human rotavirus strain different from types 1 and 2--a new subgroup? Epidemiology of subgroups in a Swedish and an Ethiopian community.

    abstract::A possible new subgroup of human rotavirus was found by crossed immunoelectrophoresis and enzyme-linked immunosorbent assay. The epidemiology of the established subgroups 1 and 2 and this new variant was studied in two different communities. Of 398 rotavirus isolates from Malmö, Sweden, 26.8% were of type 1, 71.7% of ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890120205

    authors: Tufvesson B

    更新日期:1983-01-01 00:00:00