Use of recombinant glycoprotein antigens gB and gH for diagnosis of primary human cytomegalovirus infection during pregnancy.

abstract：:Seventeen out of 30 patients with chronic hepatitis type B with hepatitis B e antigen (HBeAg) in serum remained persistently positive for e antigen, while 13 seroconverted to antibody (anti-HBe) when followed over a period of one to five years. Initial levels of serum hepatitis B virus (HBV) markers, such as the hepat...

journal_title：Journal of medical virology

authors： Alberti A,Pontisso P,Realdi G

更新日期：1982-01-01 00:00:00

abstract：:GII.b norovirus is an obligatory recombinant with an open reading frame (ORF) 1 comprising the GII.b genotype and the ORF 2 region corresponding to one of a number of other norovirus genotypes. GII.b is the second most common genotype after GII.4 associated with gastroenteritis outbreaks in Victoria, Australia. The st...

journal_title：Journal of medical virology

authors： Bruggink LD,Marshall JA

更新日期：2013-08-01 00:00:00

abstract：:Hepatitis C virus (HCV) exposure in blood donors is determined serologically by the detection of anti-HCV antibodies in serum or plasma. However, a "window" period of 30-70 days after exposure exists where specific antibodies to HCV antigens are not detected. The use of nucleic acid testing for the detection of HCV RN...

journal_title：Journal of medical virology

authors： Leary TP,Gutierrez RA,Muerhoff AS,Birkenmeyer LG,Desai SM,Dawson GJ

更新日期：2006-11-01 00:00:00

abstract：:The objective of this study was to determine the use of immune-complex dissociated (ICD) p24 antigen detection for the diagnosis and prognosis of HIV-1 infection in Ugandan children. Plasma collected prospectively from children born to HIV-1 infected Ugandan women was stored and later analyzed for the presence of neut...

journal_title：Journal of medical virology

authors： Guay LA,Hom DL,Kabengera SR,Piwowar-Manning EM,Kataaha P,Ndugwa C,Marum LH,Kalyesubula I,Jackson JB

更新日期：2000-12-01 00:00:00

abstract：:Enzyme immunoassay (EIA) for parainfluenza virus type 1, 2, and 3 antibodies was compared with the complement fixation test (CF) as a diagnostic method in 180 patients with respiratory symptoms. The CF test detected rises in parainfluenza virus antibodies in 30 cases, whereas EIA detected 47 rises. Patients with antib...

journal_title：Journal of medical virology

authors： Julkunen I

更新日期：1984-01-01 00:00:00

abstract：:A hybrid cell line producing monoclonal antibodies recognizing an epitope encoded by the pre-(S)2 region of hepatitis B virus (HBV) genome was obtained by fusion of mouse myeloma cells with lymphocytes from mice immunized with HBV. The monoclonal antibody Mo-F124 secreted from the hybrid line reacted with the pre-S(2)...

journal_title：Journal of medical virology

authors： Budkowska A,Riottot MM,Dubreuil P,Lazizi Y,Brechot C,Sobczak E,Petit MA,Pillot J

更新日期：1986-10-01 00:00:00

abstract：:Physicochemical studies of hepatitis B e antigen (HBeAg) revealed a clear cut difference between e1 and e2 antigen. The e1 antigen was found to have a MW of Ca 150,000 and a pI of 6.4-7.2, whereas both the MW and pI of the e2 antigen were heterogeneous depending upon the source of serum. Sera obtained from asymptomati...

journal_title：Journal of medical virology

authors： Yamada E,Ohori H,Ishida N

更新日期：1979-01-01 00:00:00

abstract：:HIV-1 infections due to non-B subtypes are increasing rapidly in number and spreading across Europe. The genetic nature of HIV-1 non-B variants containing subtype G sequences at the protease (PR)-coding region are described from 48 unrelated subjects living in Spain. Phylogenetic analyses of the HIV-1 reverse transcri...

journal_title：Journal of medical virology

authors： Holguín A,Alvarez A,Soriano V

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:Although the effectiveness of direct-acting antivirals (DAAs) for the treatment of chronic hepatitis C virus (HCV) has been reported in real-world settings, predictive factors of treatment failure are lacking. Therefore, we sought to explore the baseline predictors of treatment response to DAAs. METHODS:T...

journal_title：Journal of medical virology

authors： Ridruejo E,Piñero F,Mendizabal M,Cheinquer H,Wolff FH,Anders M,Reggiardo V,Ameigeiras B,Palazzo A,Alonso C,Schinoni MI,Zuain MGV,Tanno F,Figueroa S,Santos L,Peralta M,Soza A,Vistarini C,Adrover R,Fernández N,Perez

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:The data on the seasonality of respiratory viruses helps to ensure the optimal vaccination period and to monitor the possible outbreaks of variant type. OBJECTIVES:This study was designed to describe the molecular epidemiology and seasonality of acute respiratory infection (ARI)-related respiratory viruses ...

journal_title：Journal of medical virology

authors： Jeon JH,Han M,Chang HE,Park SS,Lee JW,Ahn YJ,Hong DJ

更新日期：2019-08-01 00:00:00

abstract：:A procedure is described for the detection of hepatitis C virus (HCV) RNA in blood by means of the polymerase chain reaction (PCR) in which the reverse transcription step and two rounds of amplification are carried out in a single tube. This results in fewer manipulations, reduced risk of contamination, and economy of...

journal_title：Journal of medical virology

authors： Lin HJ,Shi N,Mizokami M,Hollinger FB

更新日期：1992-11-01 00:00:00

abstract：:Guinea pig infection with a highly passaged XJ prototype strain of Junín virus by the intramuscular route (IM) was carried out in order to study viral tropism modification in this host. The neurotropism of this strain was demonstrated by viral isolation, meningitis, and by the presence of Junín antigens as shown by im...

journal_title：Journal of medical virology

authors： Oubiña JR,Carballal G

更新日期：1985-02-01 00:00:00

abstract：:Although there is a low prevalence rate (around 1% of the population) of infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in Chile, little is known about the diversity and molecular characteristics of the circulating viruses. In the present study, 40 HBV and 57 HCV samples from Santiago City, Chile, ...

journal_title：Journal of medical virology

authors： Di Lello FA,Piñeiro Y Leone FG,Muñoz G,Campos RH

更新日期：2009-11-01 00:00:00

abstract：:Human papillomaviruses (HPV) are the causative agents of most cervical carcinomas. A complete understanding of the HPV types that cause cervical carcinoma is needed as vaccines are designed. Fresh tissues are not always available for such studies. We therefore sought to determine the feasibility of HPV studies using f...

journal_title：Journal of medical virology

authors： Bryan JT,Taddeo F,Skulsky D,Jansen KU,Frain BM,Qadadri B,Brown DR

更新日期：2006-01-01 00:00:00

abstract：:Citrullinated histone H3 (H3Cit) is the product of the conversion of peptidylarginine to citrulline in histone H3. We evaluated the H3Cit level in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) tissues and assessed its association with Beclin1 messenger RNA (mRNA) (a key autophagic regulator). The leve...

journal_title：Journal of medical virology

authors： Lu M,Zhang X,Xu Y,He G,Liu Q,Zhu J,Zhang C

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Patients with thalassemia may also have cardiac abnormalities due to congenital problems, anemia, and increased burden of iron in their myocardium. This study was designed to evaluate the effects of direct acting antiviral (DAA) therapy on the cardiac function of hepatitis C virus (HCV)-infected patients wit...

journal_title：Journal of medical virology

authors： Khosravi A,Karimi-Sari H,Abedi-Andani M,Behnava B,Namvar A,Anvar A,Alavian SM

更新日期：2019-03-01 00:00:00

abstract：:No data on antiviral response of HBV genotypes E-H are available so far although these HBV genotypes contribute significantly to the global HBV burden. Of 49 patients with HBV genotypes E-H, 23 received interferon (IFN)-alpha, 12 nucleos(t)ide analogues and 14 patients were untreated. HBV genotype was determined by di...

journal_title：Journal of medical virology

authors： Erhardt A,Göbel T,Ludwig A,Lau GK,Marcellin P,van Bömmel F,Heinzel-Pleines U,Adams O,Häussinger D

更新日期：2009-10-01 00:00:00

abstract：:The aim of the study was to assess whether high-risk pregnant women have a higher prevalence of HEV during the perinatal period. This was a cross-sectional study of 428 patients: Group 1, 127 women with a high-risk pregnancy; Group 2, 97 asymptomatic people with reactivity to HCV or HBV; Group 3, 94 patients with clin...

journal_title：Journal of medical virology

authors： Baptista-González H,Trueba-Gómez R,Rosenfeld-Mann F,Roque-Álvarez E,Méndez-Sánchez N

更新日期：2017-11-01 00:00:00

abstract：:Previous investigations of fomite transmission have focused on the presence of pathogens on inanimate objects in clinical settings. There has been limited investigation of fomite transmission in non-clinical pediatric settings where there is a high prevalence of respiratory virus infections. Over a 5 week period, this...

journal_title：Journal of medical virology

authors： Gralton J,McLaws ML,Rawlinson WD

更新日期：2015-06-01 00:00:00

abstract：:It was reported previously food-borne transmission of hepatitis E virus (HEV) to humans from deer meat. The present study attempted to clarify whether eating uncooked deer meat is a major epidemiological risk factor for HEV infection in Kasai, a city in western Japan. In total, 45 volunteer subjects with experience of...

journal_title：Journal of medical virology

authors： Tei S,Kitajima N,Ohara S,Inoue Y,Miki M,Yamatani T,Yamabe H,Mishiro S,Kinoshita Y

更新日期：2004-09-01 00:00:00

abstract：:The present study compared the efficacy of standard and extended durations of PEG-IFNα-2a monotherapy for treatment of HBeAg-negative Chinese patients with chronic hepatitis B. Patients were randomized to receive standard therapy (n = 38; 48 weeks treatment) or extended therapy (n = 42; 72 weeks treatment). Extended t...

journal_title：Journal of medical virology

authors： Chen X,Chen X,Chen W,Ma X,Huang J,Chen R

更新日期：2014-10-01 00:00:00

abstract：:The efficacy of interferon therapy for hepatitis C virus (HCV) infection improved remarkably. However, virologic relapse occurs in a substantial proportion of patients with virologic response (defined as an HCV RNA level below 50 IU/ml at the end-of-treatment). A highly sensitive RT-nested PCR assay capable of detecti...

journal_title：Journal of medical virology

authors： Kinai E,Hanabusa H,Kato S

更新日期：2007-08-01 00:00:00

abstract：:Replication of HIV-1 inside host cells is dependent on both viral and host factors. MicroRNAs are small noncoding RNAs that regulate protein synthesis. MicroRNAs may control viral replication either by directly targeting the viral genome or indirectly through cellular proteins that are required during the viral lifecy...

journal_title：Journal of medical virology

authors： Dubey RC,Alam NB,Gaur R

更新日期：2020-12-24 00:00:00

abstract：:Previous studies on patients who develop drug resistant HIV-1 variants have shown that continued use of failing regimens might provide clinical benefit. However, the effect of long-term exposure to drug resistant variants may lead to emergence of compensatory mutations that may jeopardize this effect. In this study, w...

journal_title：Journal of medical virology

authors： Machouf N,Thomas R,Nguyen VK,Trottier B,Boulassel MR,Wainberg MA,Routy JP

更新日期：2006-05-01 00:00:00

abstract：:The oncoprotein Tax was characterized genetically from a large cohort of human T-cell lymphotropic virus type 1 (HTLV-1) seropositive individuals from the most endemic region of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and HTLV-1 infection in Argentina, the province of San Salvador de Jujuy....

journal_title：Journal of medical virology

authors： Iñiguez AM,Gastaldello R,Otsuki K,Balangero M,Carvalho Costa F,Remondegui C,Paula Vicente AC,Gallego S

更新日期：2010-08-01 00:00:00

abstract：:Since outbreaks of severe acute hemorrhagic conjunctivitis occur worldwide [Hierholzer and Hatch, 1985] and the majority of the epidemics are caused by enterovirus 70 (EV-70), we developed an EV-70 IgM ELISA to simplify the diagnosis of these outbreaks. The test is based on the capture antibody technique and the use o...

journal_title：Journal of medical virology

authors： Wulff H,Anderson LJ,Pallansch MA,de Souza Carvalho RP

更新日期：1987-04-01 00:00:00

abstract：:Thirty susceptible rhesus monkeys were inoculated with cell-free varicella-zoster virus strain OKA or strain KMcC. Both wild and attenuated strains were used. No clinical signs characteristic of human varicella were seen in any of the animals. Virus was not isolated from throat swabs, blood, or cerebrospinal fluid. An...

journal_title：Journal of medical virology

authors： Asano Y,Albrecht P,Behr DE,Neff BJ,Vickers JH,Rastogi SC

更新日期：1984-01-01 00:00:00

abstract：:Herpes simplex virus (HSV) establishes latency in neurons and recurrent infections in oral mucosa. This prospective study analyzes HSV prevalence in oral mucosal brush samples from men with known human papillomavirus (HPV) status. We hypothesized that HSV-1-infection could facilitate HPV persistence as a cofactor. Thi...

journal_title：Journal of medical virology

authors： Mäki J,Paavilainen H,Kero K,Hukkanen V,Syrjänen S

更新日期：2018-03-01 00:00:00

abstract：:To assess the prevalence of HPV infection in the genital tracts of women with normal PAP smears, a random series of 109 women was reexamined using colposcopy, a further PAP smear, and punch biopsies taken from the cervix (in 33 cases), vagina (212 cases), and anus (20 cases). The biopsy material was examined using rou...

journal_title：Journal of medical virology

authors： Syrjänen S,Saastamoinen J,Chang FJ,Ji HX,Syrjänen K

更新日期：1990-08-01 00:00:00

abstract：:Tumor necrosis factor receptor superfamily member 10 (TNFRSF10) is a death domain-containing receptor for the apoptotic ligand TNFSF10, which involves multiple processes, including hepatocarcinogenesis and immune response against HBV infection. Several single nucleotide polymorphisms (SNPs) were identified as expressi...

journal_title：Journal of medical virology

authors： Wen J,Song C,Liu J,Chen J,Zhai X,Hu Z

更新日期：2016-03-01 00:00:00