Heterogeneous nature of HIV-1 recombinants spreading in Spain.

abstract：:An "in-house" recombinant virus protease inhibitor susceptibility assay was carried out (median of 3 per patient) retrospectively in 26 patients failing HIV protease inhibitor based therapy at regular intervals to the initiation of the first protease inhibitor. Patients were treated with either indinavir (N = 6), rito...

journal_title：Journal of medical virology

authors： Servais J,Plesséria JM,Lambert C,Fontaine E,Robert I,Arendt V,Staub T,Schneider F,Hemmer R,Schmit JC

更新日期：2002-07-01 00:00:00

abstract：:Here, we studied the role of nitric oxide (NO) production during the first steps of the respiratory infection of BALB/c mice with herpes simplex virus type 1 (HSV-1), strain F. Nitric oxide synthase II (NOS-II) mRNA and protein were detected by reverse transcription (RT)-PCR and dot blot, respectively in samples of lu...

journal_title：Journal of medical virology

authors： Gamba G,Cavalieri H,Courreges MC,Massouh EJ,Benencia F

更新日期：2004-06-01 00:00:00

abstract：:Sera from 31 human immunodeficiency virus (HIV)-infected patients, representing different clinical stages of HIV infection, were assayed for antibodies against measles and mumps viruses by various serological tests and compared to 23 healthy controls. Sera from four patients (two primary, one asymptomatic, and one acq...

journal_title：Journal of medical virology

authors： Kövamees J,Sheshberadaran H,Chiodi F,Schwartz S,Orvell C,Fenyö EM,Norrby E

更新日期：1988-09-01 00:00:00

abstract：:Despite prolonged undetectable plasma viral load some HIV-1 infected patients have been reported to develop resistance-associated mutations leading to treatment failure. The mechanisms for this phenomenon and the point of origin for residual viral evolution are still not elucidated. In order to quantify cell-associate...

journal_title：Journal of medical virology

authors： Kupfer B,Matz B,Däumer MP,Roden F,Rockstroh JK,Qurishi N,Spengler U,Kaiser R

更新日期：2007-10-01 00:00:00

abstract：:HIV is among the most generically variable of human pathogens. A comprehensive and detailed description of HIV strains in the pandemic is an important foundation for diagnosis, treatment, and prevention. The current sequence database for HIV includes almost 800 complete genome sequences, documenting HIV-1 groups M, O,...

journal_title：Journal of medical virology

authors： McCutchan FE

更新日期：2006-01-01 00:00:00

abstract：:To determine whether unconventional pathogens causing subacute spongiform encephalopathy may be present in blood products, a newly developed hepatitis B vaccine and a widely used blood product were injected into mice and rats. As only a few aged mice in the test and the control groups showed spongiform encephalopathic...

journal_title：Journal of medical virology

authors： Tateishi J,Tsuji S

更新日期：1985-05-01 00:00:00

abstract：:Recently developed monoclonal antibodies against the 42,000-dalton major inner capsid protein were used in an enzyme immunoassay to subgroup a total of 156 rotavirus specimens obtained from Japanese infants and young children with acute gastroenteritis during the period between December 1981 and April 1983. Only 2 spe...

journal_title：Journal of medical virology

authors： Nakagomi O,Nakagomi T,Oyamada H,Suto T

更新日期：1985-09-01 00:00:00

abstract：:No controlled trial in patients with chronic hepatitis B virus (HBV) infection on long-term entecavir (ETV) treatment, comparing switching to tenofovir disoproxil fumarate (TDF) with continuing the therapy, has been reported. Twenty-seven nucleos(t)ide-naïve patients with chronic HBV who underwent ETV therapy for ≥5 y...

journal_title：Journal of medical virology

authors： Iida-Ueno A,Enomoto M,Kozuka R,Tamori A,Kawada N

更新日期：2019-07-01 00:00:00

abstract：:In order to elucidate the pathogenesis of variant B human herpesvirus 6 (HHV-6) infection in skin tissues, an A431 cell line was inoculated with variant B HHV-6. HHV-6 causes abortive infection in the A431 cells, because neither late antigen (OHV-3 antigen) nor progeny virus is produced. Maximum levels of HHV-6 antige...

journal_title：Journal of medical virology

authors： Yoshikawa T,Goshima F,Akimoto S,Ozaki T,Iwasaki T,Kurata T,Asano Y,Nishiyama Y

更新日期：2003-09-01 00:00:00

abstract：:Stored demographic data and HIV RT and protease sequences of 877 HIV patients attending for the first time the HIV/AIDS outpatient clinics of a reference Infectious Diseases centre in Northern Italy between 1999 and 2006 were stratified by 3-year spanning periods according to date of HIV infection. In the period 1980-...

journal_title：Journal of medical virology

authors： Baldanti F,Paolucci S,Ravasi G,Maccabruni A,Moriggia A,Barbarini G,Maserati R

更新日期：2008-06-01 00:00:00

abstract：:Vaccine effectiveness may wane with increasing time since vaccination. This analysis used the Victorian sentinel general practitioner (GP) network to estimate vaccine effectiveness for trivalent inactivated vaccines in the 2012 season. A test-negative design was used where patients presenting to GPs with influenza-lik...

journal_title：Journal of medical virology

authors： Sullivan SG,Komadina N,Grant K,Jelley L,Papadakis G,Kelly H

更新日期：2014-06-01 00:00:00

abstract：:Most dengue virus (DENV) infections remain asymptomatic. This increases the risk of DENV transfusion transmission (TT-DENV) during outbreaks. We evaluated DENV viremia in 8475 blood donations assembled in minipools for the presence of DENV RNA. The tested samples were obtained between February and May, 2016, during a ...

journal_title：Journal of medical virology

authors： Slavov SN,Santos EV,Hespanhol MR,Rodrigues ES,Haddad R,Ubiali EMA,Covas DT,Kashima S

更新日期：2020-10-22 00:00:00

abstract：:The prevalence study and the characterization of hepatitis C virus (HCV) was carried out in the Philippines and the sequence determination of the 5'-untranslated region (5'-UTR)-Core and the NS5B regions of HCV was carried out in this study. An HCV strain (SE-03-07-1689) collected in Metro Manila, Philippines, belonge...

journal_title：Journal of medical virology

authors： Kageyama S,Agdamag DM,Alesna ET,Leaño PS,Heredia AM,Abellanosa-Tac-An IP,Jereza LD,Tanimoto T,Yamamura J,Ichimura H

更新日期：2006-11-01 00:00:00

abstract：:Screening for high-risk human papillomavirus (HPV) types allows the detection of women at a high risk of cervical squamous carcinomas, thereby defining a subset of patients targeted for more intensive screening and follow-up. Thirty-four cervical biopsy specimens and isolated cells from cervical smears of normal women...

journal_title：Journal of medical virology

authors： Adams V,Moll C,Schmid M,Rodrigues C,Moos R,Briner J

更新日期：1996-02-01 00:00:00

abstract：:Rotavirus is the most common etiological cause of acute viral gastroenteritis in infants and young children worldwide, yet its role in the adult population is less well understood. We have recently identified rotavirus as the causative agent of severe diarrhea in adults, specifically in two gastroenteritis outbreaks i...

journal_title：Journal of medical virology

authors： Feeney SA,Mitchell SJ,Mitchell F,Wyatt DE,Fairley D,McCaughey C,Coyle PV,O'Neill HJ

更新日期：2006-08-01 00:00:00

abstract：:This open, randomized study was conducted in healthy Chinese youngsters, aged between 10 and 19 years to compare the reactogenicity and immunogenicity of two vaccines: the combined vaccine against hepatitis A and B was administered in a two-dose schedule with the profile of the corresponding monovalent vaccines, while...

journal_title：Journal of medical virology

authors： Lee SD,Chan CY,Yu MI,Wang YJ,Chang FY,Lo KJ,Safary A

更新日期：1999-09-01 00:00:00

abstract：:Immunoglobulin class-specific determination by ELISA and a virus neutralization test (NT) were compared for the detection of the serum antibody responses after vaccination of infants with the RIT 4237 rotavirus vaccine (of bovine origin). A capture method was applied for specific IgM determination by ELISA because of ...

journal_title：Journal of medical virology

authors： Delem A,Vesikari T

更新日期：1987-03-01 00:00:00

abstract：:The relationship between cytomegalovirus (CMV) infection and cardiac allograft rejection is controversial, some authors reporting a significant association, others not, on the basis of the results of conventional virological diagnosis by culture or serology. This problem was reinvestigated in 88 patients using a semi-...

journal_title：Journal of medical virology

authors： Fernando S,Booth J,Boriskin Y,Butcher P,Carrington D,Steel H,Tryhorn Y,Corbishley C,Keeling P,Murday A

更新日期：1994-04-01 00:00:00

abstract：:A multiplex polymerase chain reaction (PCR) assay that is capable of detecting and typing six serotypes of respiratory adenovirus (Ad) was developed, using multiple sets of type-specific primers. The detection of each different serotype depended on distinguishing different numbers and sizes of amplification products o...

journal_title：Journal of medical virology

authors： Na BK,Kim JH,Shin GC,Lee JY,Lee JS,Kang C,Kim WJ

更新日期：2002-04-01 00:00:00

abstract：:Exacerbations of chronic hepatitis B have been associated with accumulation of mutations in the HBV core gene, with amino acid (aa) substitutions clustering between aa 50 and 69. This region of the nucleocapsid protein is known as an immunodominant epitope for CD4+ T-lymphocytes, however the impact of these mutations ...

journal_title：Journal of medical virology

authors： Torre F,Cramp M,Owsianka A,Dornan E,Marsden H,Carman W,Williams R,Naoumov NV

更新日期：2004-03-01 00:00:00

abstract：:The natural history of chronic hepatitis B virus (HBV) infection is highly variable, ranging from a benign course to one of shortened life expectancy. Liver histology represents an accurate tool for assessing progressive liver disease, and has been used in five recent Phase III clinical trials of the oral nucleoside a...

journal_title：Journal of medical virology

authors： Leung N

更新日期：2000-07-01 00:00:00

abstract：:Amphotropic murine leukemia virus (MLV) replicates in cells from various mammalian species including humans and is a potential contaminant in MLV vector preparations for human gene transfer studies. In general, MLV replication depends on the expression of viral genes under the control of 75 bp enhancer elements in the...

journal_title：Journal of medical virology

authors： Reuss FU,Berdel B,Heber R,Bantel-Schaal U

更新日期：2002-10-01 00:00:00

abstract：:This is a case study of a child who developed roseola infantum first, then varicella, and was later affected by acute cerebellar syndrome, severe truncal ataxia, and myoclonic dystonia. Human herpesvirus 6 (HHV-6) A and B were detected in the cerebrospinal fluid (CSF) and peripheral blood, respectively, upon ataxia on...

journal_title：Journal of medical virology

authors： Borghi E,Pagani E,Mancuso R,Delbue S,Valli M,Mazziotti R,Giordano L,Micheli R,Ferrante P

更新日期：2005-03-01 00:00:00

abstract：:Chikungunya fever a re-emerging infection with expanding geographical boundaries, can mimic symptoms of other infections like dengue, malaria which makes the definitive diagnosis of the infection important. The present study compares the utility of four laboratory diagnostic methods viz. IgM capture ELISA, an in house...

journal_title：Journal of medical virology

authors： Reddy V,Ravi V,Desai A,Parida M,Powers AM,Johnson BW

更新日期：2012-11-01 00:00:00

abstract：:Human T-cell lymphotropic virus (HTLV) antibody screening is not recommended uniformly before transplantation in Western countries. In the year 2001, the first cases of HTLV-I infection acquired through organ transplantation from one asymptomatic carrier were reported in Europe. All three organ recipients developed a ...

journal_title：Journal of medical virology

authors： Toro C,Benito R,Aguilera A,Bassani S,Rodríguez C,Calderón E,Caballero E,Alvarez P,García J,Rodríguez-Iglesias M,Guelar A,del Romero J,Soriano V,HTLV Spanish Study Group.

更新日期：2005-06-01 00:00:00

abstract：:We report a real-life 3D therapy failure in a patient treated with ombitasvir (OMV)/paritaprevir/ritonavir and dasabuvir without ribavirin (3D-R). He had therapy failure at week 12 after the end of treatment. We detected resistance-associated substitutions (RASs) plus polymorphisms on NS3, NS5A, and NS5B target region...

journal_title：Journal of medical virology

authors： Marascio N,Pavia G,Romeo I,Talarico C,Di Salvo S,Reale M,Marano V,Barreca GS,Fabiani F,Perrotti N,De Siena M,Giancotti F,Gravina T,Alcaro S,Artese A,Torti C,Liberto MC,Focà A

更新日期：2018-07-01 00:00:00

abstract：:The reliability of the polymerase chain reaction (PCR) for prenatal diagnosis of human cytomegalovirus (HCMV) infection was determined by retrospective testing of 35 amniotic fluids identified previously as positive or negative for HCMV by virus isolation. Amniocentesis was performed in 26 pregnant women with primary ...

journal_title：Journal of medical virology

authors： Revello MG,Baldanti F,Furione M,Sarasini A,Percivalle E,Zavattoni M,Gerna G

更新日期：1995-12-01 00:00:00

abstract：:Therapy failure due to drug resistance development is a common phenomenon in HIV-infected patients. However, when the drug pressure leads to the earliest selection of drug-resistant HIV-1 populations is still unclear. In this study, the extent to which selection of the HIV-1 reverse transcriptase M184I/V mutations occ...

journal_title：Journal of medical virology

authors： Bergroth T,Ekici H,Gisslén M,Loes SK,Goh LE,Freedman A,Lampe F,Johnson MA,Sönnerborg A

更新日期：2009-01-01 00:00:00

abstract：:A panel of deoxyoligonucleotide probes for studying the genetic variability and genotyping of Tick-borne encephalitis virus (TBEV) strains by molecular hybridization of nucleic acids (MHNA) was created. This panel allows to estimate the genetic structure of individual TBEV strains, as the targets for probes are both v...

journal_title：Journal of medical virology

authors： Demina TV,Dzhioev YP,Verkhozina MM,Kozlova IV,Tkachev SE,Plyusnin A,Doroshchenko EK,Lisak OV,Zlobin VI

更新日期：2010-05-01 00:00:00

abstract：:The effect of HHV-6 strain A infection on the expression of Epstein-Barr virus- (EBV-) encoded growth transformation-associated genes in two EBV-positive Burkitt lymphoma cell lines, Akata and P3HR-3, was investigated. The results indicate that HHV-6A upregulates the expression of the latent membrane protein LMP-1 in ...

journal_title：Journal of medical virology

authors： Cuomo L,Trivedi P,de Grazia U,Calogero A,D'Onofrio M,Yang W,Frati L,Faggioni A,Rymo L,Ragona G

更新日期：1998-07-01 00:00:00